LOCUS       NZ_CP018829.1          10375 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP018829.1 Enterococcus faecium strain ISMMS_VRE_12 plasmid
            p3_ISMMS_VRE12, complete sequence.
ACCESSION   NZ_CP018829
VERSION     NZ_CP018829.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:24:41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2760
            Orig. end    :: 13135
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10375
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5375]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5375
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10375
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10375
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             284..601
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MTISKVIKQKRIEKQLTQEDLAEMLLVSKKTISNWENGRTIPDTE
                     NLIQFAKLFDLSLDNILLGEEKIMVKNYGKKSYKNTNTIISFCNFFKFSFHLNSVRILL
                     F"
     CDS             891..2072
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKIT
                     KELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVLTG
                     AKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIATLPI
                     GILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISDTGRD
                     FLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNIHVPVR
                     ESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVAMIFFHV
                     FENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQK"
     CDS             complement(2301..3449)
                     /gene_functions="other (smcogs) SMCOG1192:transposase
                     (Score: 399.5; E-value: 2.4e-121)"
                     /gene_kind="other"
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYEE
                     VKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRFKS
                     KKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKY
                     YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLS
                     RRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKD
                     GKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     CDS             complement(3466..3870)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     CDS             complement(4407..4868)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.7; E-value: 3.7e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPDI
                     ETLKKICEFYSTNINSILNEDNLKNKQNNLLVLTAIIFNIFVTILGLFELIQMNFFSFT
                     HGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTIFFPLVILIILLS"
     CDS             5001..5375
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_9"
                     /sec_met_domain="Lactococcin_972 (E-value: 1.9e-09,
                     bitscore: 28.1, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFLCLSALMGVLLTSGGIVSATEALNLDVPEDHTAIYGGGMEA
                     TEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKAGV
                     RAYATCNATLTGNTGWWNVY"
     CDS             5429..7555
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQY
                     KDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKYG
                     TPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFDTI
                     KDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTLSIY
                     HLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINIHNEAENNSLKYWERTT
                     NLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQENNKEFFI
                     GQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTTYILVPKKY
                     KEYAKMIEKNYLEDIQFRLEDSPPQAPYKTPNLKNLKIKLIFVNNNQKYFSFNTLYGKA
                     KDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQINPYIKEFNL
                     ENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIFVSFTINSKKIA
                     LKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFMIFLINLITSIII
                     YKKNSFKYFKENIL"
     CDS             7552..8172
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 136.7; E-value:
                     1.7e-41)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTLL
                     NNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAKKF
                     NSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEPTGN
                     LDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     CDS             8286..8423
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESYC
                     "
     CDS             8383..8544
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MKLNQLKNGRVIARFLVEVTKSGHIIIMTRRKSDKKLAKNIAECL
                     IKLSVLAK"
     CDS             8865..9245
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEALQ
                     MSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASGDA
                     QRLSENLKIMQKELQKIWQQLR"
     CDS             9227..10141
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIRM
                     LYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHNHI
                     VINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKLKEK
                     NEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKKKVRS
                     NRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTPEQPEI
                     RPARRNHEQHVERGTDHQQELSL"
ORIGIN
        1 atactcaaat aaaacaaatg caaaagttac tcgaccagca acaacaactc accttgcagg
       61 caaatcaaca gatcgaaaaa ctgcaagaac agttacaatt agcttatacg gaagaacctg
      121 aagaagagga attaacttct gtcaataaag aaaacaacaa tgcaataaca acagaaaaaa
      181 agtggtggaa attttggtaa caattaccaa ctttccataa agaagaaatc aatttctata
      241 gactctatct ttctaagaat aaaaaatatg tttaggtgat caaatgacta taagtaaagt
      301 aatcaaacaa aaaagaatag aaaaacaact aactcaagaa gatttagctg aaatgctttt
      361 agtatctaaa aaaaccattt ctaattggga aaatggtcga acaataccag atacagaaaa
      421 tttaattcag tttgctaagt tatttgattt atcactagac aatattttgt taggagaaga
      481 aaaaattatg gtaaaaaatt atggtaaaaa atcatacaaa aacactaata ctattatttc
      541 attttgtaat ttttttaagt ttagttttca ccttaattca gtccggattc ttttatttta
      601 gccattcaat tgccacttgg ttattaatat tttttctaag tttactatta ataattaata
      661 cattaataat taatacttta attattatct ttaataaaca tagaaactta tttcttcaca
      721 gcatatttcc aattgtttta ttaatttttc tatactttat ataaaaagat agaactattt
      781 agtaagataa aaaagtagct aattgtaatt ttcgtctaaa actcaaaact agtaaaaata
      841 actttattgt gttattttta tttataaatt atgaaaaagg acctttcgaa atgaaaaata
      901 atagaatcta caaaaatcag ttgaattatg ggcttttatt gccagttttt ctgctatgta
      961 tcattggatt actttcttta tatgttgctt tatatcacga ctcttacact aattcaaaaa
     1021 tcacaaaaga attaattaaa caagtattgt ggtatagtat tgggttcact tcagcaataa
     1081 ctatttattt ttttaatcct aaaattttgt ggaaattaac tcctatattt tacggattat
     1141 gcatcataat gttattactt ctcttgaaat tctataatcc acaattagca gtcttaactg
     1201 gagcaaaaaa ttggttttat attgctggtt tttcgtttca acctactgag ttagtcaaaa
     1261 taggatacac ccttatgcta gctaaaataa ccgtcaatta tcagcaaaaa tctattacta
     1321 gtaatacgaa agatgattgg atttatttac ttaaaacttt tattgctact cttccaatag
     1381 gaatattatt attttttcag aacgatctag gaacaatgtt agtcttcatt gttatttata
     1441 tttttatttt gtttacgtct aacataaata taaaaataat tgccccaata atcgccattg
     1501 gtgttgtttt atccttaata tttttatatt tggttatatc agatacagga agagatttct
     1561 tattaaaaat aggatttcac gactatcagt ttaaaagaat agactcatgg ttgaatccat
     1621 ttttagatcc aaatggatct agctatcagt tagcaaatag tttaattgct attggctctg
     1681 gcggactttt aggtactggt tttaatgtat caaacattca cgttcctgtt agagaatccg
     1741 atatgatatt ttctgtaatt ggagaaaatt ttggctttat aggaagttgt cttgtaatat
     1801 tcctatactt ttatttaatt tatcaaatgt ataaaacatg ttttaaaagc aataacttat
     1861 ttttcaccta tatcggtata ggcattgttg caatgatttt ttttcatgtt tttgaaaata
     1921 taggtgcaag tatcggatta ctacctctaa ctggtattcc actcccctat attagtcaag
     1981 gtggttctgc cattcttagt aattttttgg ggttgggatt tatgttgtgt tgtagtagat
     2041 atactaacga aaaaaaagga acacaaaaat gaattcaaaa taacacttta tgaatagaat
     2101 gtctatttca ataaaaatta tgatacctta aagttaatca gtgaactact caccacttag
     2161 ctaaacctga cggttcttaa cgcttgaagt gggagcttct tgggaataga gcatacttga
     2221 tagcgtattt ctttactaac agcggtgtct cttatttacc aagctatccc cgtagttcct
     2281 acggttcttg atgattggat ctaagccaat cccatagaat gtagtcttag accttcggtc
     2341 agaatattga tactagcatt gatatcacga tcatgatgag tatgacaaac aggacaagtc
     2401 cattctcgaa tttcaagaga tttcttgcca tctttatgtc cgcactctga acaaatctga
     2461 ctagacggaa accatttatc tactttgatg atttttcgtc cataccagtc agccttgtat
     2521 tgtaatttag tcacaaactt tgaccaagaa acatcagaaa tacttttagc taatttatga
     2581 tttcgcaaca taccttttgt gtttaagtct tcaatacaga taatatcgtg atttttgatc
     2641 atttctgtac tcaacttatt cagaaaatca gtacgttgat tcattacttt ttcatgcaat
     2701 ctagctactt tgcgtttttg tttttgataa tttttagctt caaatagatt ggtaccttta
     2761 tttttagcca ataaagcacg cctagacaat ttgcgttgtt cacgctttag tttcttttcc
     2821 attttggacg tgaatttatt attatcaatt ttttgtccat cagaaagaat cgcaaagtcc
     2881 ataataccta agtcaatacc aattgtggaa ttagttttag gtaattcgat aatttcttct
     2941 ttacacaaca aagaaatata gtatttaccg ctagaatgac gtgatattgt agcggatttg
     3001 ataatccctt ttggttgtct atgaagctta attcttacta atgacttcaa tttaggaact
     3061 ttgatgaatt tactatcaat caaagcaact gtaccatttt gattattcgt tgtataactc
     3121 tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc ccgaaaaaaa
     3181 ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct atcaatttct
     3241 ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat ttttttagaa
     3301 gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag attgtagacc
     3361 ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt tggatagatt
     3421 ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt tatgattgtt
     3481 tccttgattt tggatatact tcttaatcac atcaattggt gcgccaccag ttgtcagaag
     3541 acaaaaactt ttagaccaga acatttcttt ccaaagaaat tgtttgactc ttggaaagtc
     3601 acgttttatc aatcttgagc tggcactttt ataggcattg atgaattttg tcaattctgt
     3661 tttaggttga gctttgaaca taatatgaac gtggtcttta tcatgattcc actccactaa
     3721 agtaatgtga tacgattctg aaattctttc aaaagtagtt ttggcataat cagatatttc
     3781 atcatcaatc acttgtctac gatatttcgt tactaaaaca aggtggtaat aaagaagaaa
     3841 tactgaatga ttatttgtat ctaattccat gttatatcaa ctcatttctt gtatagactg
     3901 attgtaacat ggaacaaaat aaaaaggcaa tacgccttag ttgtcggtct tcgagttacc
     3961 aacggtaacc ctcataccga acggcattca tcacccacct atagaggatg ggcgacttct
     4021 gcctaattct gttaaattca aattattaca acagtcctaa cgaagaattg tttgtaaaac
     4081 aaacggataa ataataaaaa agactgctct ttcgagcagc cagttaaaaa ataatgagtg
     4141 tttattcttg aaaaagcaac gcgcttatga agcgctacca aaaatttatc atattttatg
     4201 aaaaataaca ccccagtaaa aaatgactgg taaaaattca caaagaaacg gaaagaagca
     4261 actgcagaaa atcaagcctt aaaaagagct tttgacctag accaatgaaa aatcacaaag
     4321 tgagcccctg tatcccttgg tagagaggct acttggcata gtcgacatta tgtcaactat
     4381 gcaattaaat aactaactac ttcatattag cttaataaaa taatcaaaat cactagggga
     4441 aaaaatattg tataaaaaaa tttttcattt tttaaataag aatagtaaat ataaaaataa
     4501 tttaagatat ctattactat taatccagat agagcaaacc aagtaaatat tccgtgtgta
     4561 aagctaaaaa aattcatttg aatcaattca aataaaccta atatagtaac aaatatatta
     4621 aaaataatag ctgtcaatac cagtaaatta ttttgtttat tttttaaatt atcttcattt
     4681 aaaatagaat ttatgttagt actataaaat tcacaaattt tttttagtgt ctctatatct
     4741 ggtgttgttt tgttattttc ccactttgaa atagtttgac gtgtaacatt aaattttctt
     4801 gccacatatt cttgagtata cccttttttc actcttaatt ctcttagctt agatcctaaa
     4861 tcctccattt tttctcctat gtaaacgatt atttacataa aattttatca taaaaatact
     4921 aacgcgccaa aaaagttctt tattttataa aacacactaa aataaaataa ttctagtaaa
     4981 aaagatagga gaaataagtt atgaaaaaat ttttatgtct ttctgcttta atgggtgtct
     5041 tattaactag tggaggaata gttagtgcta cagaagcttt aaatctagat gtacccgaag
     5101 accataccgc catttacgga ggaggaatgg aagctacaga agaaggattt tcttctagta
     5161 aattgagata tgctgctggc ggcggagatt tcaactgtgg ggttaatgga tttaaagttt
     5221 atgcaaatta ctaccatgct agagctaaac atagtgcaac agctaaaaat ggacgaggcg
     5281 gtcaagtacg atcagttcag aaagctggag taagagctta tgcaacatgc aatgccacac
     5341 ttactggaaa tactggttgg tggaatgttt attaaaaaag agagtttaaa ctctcttttt
     5401 tatttacatt tgaaaggaaa ttcaaaatat gttaaaaaaa ataaacgctg ttttatcact
     5461 ttttgtctgc attacaatac tattcttttc tactaatgtt ataaatggta taaagacttc
     5521 tgaagcgcta tataaaaata ccgctgaaat tcatatgcaa tataaagatg atatggactt
     5581 taacagttat ataaacgctt tgtatgaaat atctacacaa gaaaatatta atatttctca
     5641 atatagtttt actgctgtta accaactaac tattcttgct acaaacccta acgctaacaa
     5701 acactggaaa ttttctaaaa aaaatatatt agcaagaaac gattctaaag tccattatac
     5761 taataacaaa aattctaagt accaattaaa acttccaaat aattttttaa atataaatat
     5821 ttatcctttt tctcatgtgg aaaatattgg attaagtgaa atattatatg tacaaggaaa
     5881 ctcaaacaaa ttaattcctg tactgaaaaa atatggaaca cctactattt ccaatatcaa
     5941 tcaatcagat acttttcaaa ttaatactaa tattgttctt gttatctgct atcttagtat
     6001 atttattgta attactacaa ttatatttgc tttttcaaaa atgaaagaaa tcactctaaa
     6061 aaaaatgtta ggctataact cttttgatac tataaaagat tctattaaag agttaaacct
     6121 cttattttgt tctttgatta taactttcat tttatctatt tttttgagca tatattacag
     6181 taacgaaaat tttttcctat catttcttct atgtagtatt tttcatttta taattagttt
     6241 tttatttatc atagttactc taagtatcta tcatttatct agtataaaaa attatctaaa
     6301 aaattcacga ccacttaagt taaatctttg tatattaaat atctgtctat tcttaagcat
     6361 gatccttctg ttaatagctt ctacaaaagt aataaatatc cataatgaag ccgaaaataa
     6421 ttctcttaaa tattgggaaa gaactactaa tttatataaa acaaatatta ctaatcaatt
     6481 aaatagaaac aacaccgtag aagaaaataa ctacttgaaa aaagctagta aatttgttta
     6541 taaaatacag aagaattata aaacttttat tatcgcgcca tacaattacg caactatcca
     6601 agaaaataat aaagaatttt ttattggaca aaaagtttat ccaaattttg aagactatgt
     6661 tagtcaacct gctggtgcag gaatatgtgt tgatttaaac tatctaaaat attacaatcc
     6721 tatttctttt gaagaatcta ctgacttaaa tttaataaac tctgatccac taactactta
     6781 cattctagta cctaaaaaat ataaagaata tgcaaaaatg attgaaaaaa attatttaga
     6841 agacatacag tttagacttg aagactctcc tcctcaagct ccttataaaa ctcctaattt
     6901 gaaaaattta aaaataaaac taatatttgt taataataac caaaagtatt ttagttttaa
     6961 taccttatat ggaaaggcaa aagataacta tacaataact gatcccatag ttagagttat
     7021 taatccagaa ataacagaat cattattttg gggaaatata ttgactagtg atggtggatt
     7081 attttttgat cagaaacata cttcaaacca aaactttttt aatcaaatta atccgtatat
     7141 aaaagaattt aacctagaaa atatcataaa tttttcttat tctgtttttc aagaaactgg
     7201 tgaattatta tctcaaaaaa aagtaaataa attaaatgca tatctacaat atcttttaat
     7261 attaggatta tttataataa ttaattttca aatgattttt gttagtttta ctataaattc
     7321 aaaaaaaata gctttaaaaa aaatatttgg atattcacca ataagtcaag ttttagattt
     7381 atgtttactc ccttttacaa tagagttatt tgctactatg tgttttcaat tgatattttc
     7441 aaaaaacact tacttgtatt ttataatttt tatgatcttt ttaataaatc taattacttc
     7501 tattattatt tataaaaaaa atagttttaa atattttaag gagaatattt tatgatatta
     7561 tcagttgaga atttcaccct gtcaattaat aaaaaaaaga tcaaacaaaa ttggaacttt
     7621 tcaatatcag aaaaagattt tattatagta acaggaaaaa gtggtagtgg aaaaactact
     7681 ctgttaaata atttaagcct aatagataaa caatataccg gtaacttatt ctattttgaa
     7741 aagaaagttt ctaaacatga tatacaacgt ctacgaagaa atcatattag ctatttattt
     7801 caaaactatg ctcttcttga aaatcaaaca gtacaataca atttcgaatt agcaaaaaag
     7861 tttaacagta atatttccaa tgatcatatt tataatttat taacagattt ttctttgcca
     7921 aaagatatct taaaagaaaa aatctttctc ttaagcggtg gagaacaaca aagaatagca
     7981 ttaattagaa atatgttaaa accatttgat atattatttg cagatgaacc tacaggaaat
     8041 ttagataaag aaaactcaac ttttataatg aactttctga aaaatttaac agaaaaagaa
     8101 aaaaaagccg ttgtactagt aacacatgac ttaaatgttc taaactatgg aactaatatt
     8161 atagaattat aatttttacc cgtgatgcta gctgatttaa aactagcacc acgggtattt
     8221 attttatatt ccatctctcc tatcccaaaa tttaaataat cacttaataa aaaggaggca
     8281 cccaagtgat tttattgaaa aaagagtatg aaaaatttta tgatagactt atttattctt
     8341 tgcaattgcc aaaaaaatta aaccgtcaat tacaaaagac ttatgaaact aaatcaactg
     8401 aagaatggga gagttattgc tagatttttg gtagaagtaa caaaaagtgg acatattatc
     8461 ataatgactc gccgaaagtc tgataaaaaa ttggctaaaa atattgctga atgtttaata
     8521 aaactatcag ttttagctaa atagttagta gtttacacaa aaaagcattt atgttttttg
     8581 ttgcaaagca acaatttcat cttcggtgaa ataagcgaaa ctttacaaaa agtggctagc
     8641 atttgctagc tttttttgta ttgtggagcg tggcttttga gggggattca agggggagct
     8701 tgcgcccctt tgacaagcgg ttatttgcac caaatacgga ggtatttggc tagcaaatat
     8761 agagcttgcc aaaccctttt agtgagcttt actcattgta cctttttagg tacaatggta
     8821 ttgcgaacga tacgtccgta ggacgtactg aaagggtggg acttatgagc gaacaaaatc
     8881 aaaatttggc tagcaattct tctaaaaaat atacctatcg atccgagcca aaacaaatca
     8941 gttttcgagt gagcgaatcc gaatttgcaa agctgaagca atcggctgaa gctttgcaaa
     9001 tgagtgtgcc ggctttcgtg aaagccaagg cacaaaacgc gcgtctggtg acaccgaaag
     9061 tggcgccaga cattgcccag gcaatcgcgc gcgatttagc caaagctgga gggaatatca
     9121 atcaaattgc taagtggtgc aatacacacc aacatgacgt tgcttctggt gacgctcaac
     9181 gtttatccga aaacctaaaa atcatgcaaa aggagctaca aaagatatgg caacaattaa
     9241 ggtaagccga accacttctt gtagtcgtgc aattaattac gcagaaccac gagcaaccat
     9301 taaaacagga ataaactgtg acgtcgatta tgccaaaagt gaaatgaaac aaattcgcat
     9361 gctgtatgga aaagacgacc gtgtacaggc acacttattg attcaatctt ttcgaccagg
     9421 agaaattacc gctgaaaaag ctaatcaact aggggcagag tatgcaaaaa aaatagcccc
     9481 cgatcaccaa atagctattt acacacatac agacaaagac catattcata atcacattgt
     9541 cattaactcc gttaatctgg agactggaaa aaaatttcaa gctcatggtc aagcatttct
     9601 aaacaaatgt tatgacctaa atgacgagat ttgtcttgca cataacttac caatcactga
     9661 gcgaggaaag aaaccagaaa aacgaaccat gtctgaaata aaattaaaag aaaaaaatga
     9721 acctgtttgg aaagacgaaa ttcggattgc gatcgatcaa acaatgaaaa acaaaaaaac
     9781 cagaacctat gaccaatttt gtaattccct caaaacattg gggattcatt gcttcaatcg
     9841 cgggaaaaat ttcacttacg aattgatcca caaaaagaaa aaagtacgat ccaacagact
     9901 aggaaaggac tacgaaaagg agacgatttt acatgagctg gacagacgag aacgaaccta
     9961 taaccaacag cgaaccaacg agctacgaag agctcgagct agcattcgcg aaactgcaga
    10021 agaagtacga agagaacaac gaactcttac gcctgaacaa ccggaaatta gaccggctcg
    10081 aagaaaccat gaacaacacg ttgaaagagg aacagaccac caacaagaat tatcgctcta
    10141 aaacgttaaa agacatagaa aacgaaataa agaaacaacg tgcttttctc gttccttata
    10201 cgcaagaaag gatacaaact acgattgatt tacaagttaa aaaactccat caagagctat
    10261 tagaccagcg aaataaggaa cagaaaaagg tgcttattca acgatcattg gattttcttg
    10321 cccccttatg ttgcttagtc ctgacactgt tcgcattttg gttagtatgg ggagg
//
