LOCUS       NZ_CP010127.1          22688 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP010127.1 Escherichia coli strain C8 plasmid B, complete
            sequence.
ACCESSION   NZ_CP010127
VERSION     NZ_CP010127.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 14:37:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 12281
            Orig. end    :: 34969
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22688
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12688]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12688
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..22688
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22688
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     CDS             447..854
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MSLTLPLMYFQTGADLSKITHHEVHYQDGFVQQAWLQPEIQLFVV
                     CIARKKGSRREIKGGMAVLTSIPASNGAELAKALDNVMRQSDELRPLAGKDENVFIPAR
                     IGISGEEPPTEQELLSVFYQQCLKHGSWGSA"
     CDS             1011..1397
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MYCWKNILRAPQHERPRVIAVDTEENVFIAESSNEYDGAKCWVVD
                     DDDSHRTRYSELQQAFDFYNQRLFDGELPECLITFQRVTLELFQGKFALSWFDRFPVQV
                     EQQKEMAAVIDQWRETTCSSTSKC"
     CDS             2098..3150
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_17"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 1.7e-20,
                     bitscore: 64.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 8.8e-48, bitscore: 154.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYILGRYVKIARYGSGGLVGGGGKEQYVEDLALWENIIKTAYCF
                     ITPSSYTAALETVNIPEKDFSNCFRFLKENFFIIPSEYNNSTENNRYSRNFLHYQSYGA
                     NPVLVQDKLKDAKVVILGCGGIGNHVSVILATSGIGEIILIDNDQIENTNLTRQVLFSE
                     NDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKVPEADIWVVSADHPFNLINW
                     VNKYCVRANQPYINAGYVNDIAVFGPLYVPGKTGCYECQKVVADLYGSEKENIDHKIKL
                     INSRFKPATFAPVNNVAAALCAADVIKFIGKYSEPLSLNKRIGIWSDEIKIHSQNMGRS
                     PVCSVCGNRM"
     CDS             3147..4361
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MNTANILSVNYGAYNAIRMLIGVYHAAFLISTGVTISQLAVLQII
                     FSVTVLILDFPLSVIADRFYRKQVVVSGVFFTILFYPLCIQSPDMLALVFSEIFYAIGI
                     CCISGAIEGWVLSALDGRNEKFTLCAHLCERVSSFGSVITGAVGILVVYFYDSYKSGYI
                     VSFFLMFVVFIVFLCVKTNGSGGEKEARDSIIKQAKESIGLITGSYNGTYFLSITCMFT
                     LGIQVIYHFWQPIMLSGESIGSLSKRELITLLMCHIGAFSMQYIANYLMPKIDVRCKLY
                     ILVCTLCSFLSSIACILLFILITDNNVVLGVAIFSIIHGMISTIPVGAQNIFISRLNDN
                     YKNIISGALGIVSLSCRVASISVLGVISVLPGNMPVTTYIFISAIACVLCGCLFLMWSF
                     KKEMV"
     CDS             4358..5161
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 60.7; E-value:
                     2.4e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MTIKHAEELTEEVILNMNYPDFVALMQQDNTPPGAEYTIDYWIKH
                     GCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKY
                     YVADACDLPFEDNSFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKIS
                     DKLINDVYNAINFRPNPLWTLEYWHQFFSERFTLVSEENHEMESQSEDELKADIYDYIF
                     NRNEFTKGLNGSLQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK"
     CDS             5146..6915
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 132.8;
                     E-value: 1.8e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_20"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 3.3e-21, bitscore:
                     67.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQKITPSKIVKHARELIIKGIESGDNSFVIFDVDGALERLEHYR
                     CQLKSFFPNSSIAYSYKSNNLAQWCQIISGKGLYAEVCSVDEMNLAKRDGFNRIVFDGP
                     LKKTSELLKAIEIGALIEVDNIDECKRLNELCKLHKLTCRIHLRLSHYYDDNLSRFGLS
                     ESEAINLLEMLISKSEYLILDGFHLHVGSNLPNAEKICKAIIQYHELILRYMPDDGTLN
                     LGSGIPADSFSASSDNPTPCPEVFFSSIYDTIKNCFGTVCDKWNYIFEPGRHLVEDFGY
                     FIGKVISTKNRYGVKVAQTNIGINWIPSIRNWDHSFTLFHNHNHISDDKSDEYIIAGFN
                     CFECDCLFPSVILPSNLSEYLFSVRGCGAYDMQTGNQWTRNLYAVYTITNDVVNISRIH
                     RRELDFRKYDVSLTPSGIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVN
                     NISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQ
                     GKGIVTNAINKLIQEYGDSDVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNG
                     VSYDQNIYSKVIG"
     CDS             complement(6972..8006)
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MMIQSHPLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQR
                     KGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDY
                     DAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKIL
                     TRKQSGIYTYTLPEKWSDESINWNENKILRPKKLYKNNCAFYGSGKVEGRVIGGNLNTL
                     TGIWGSEWMPEIRNGDILFIEDSRKSIATVERLFSMLKLNRVFDKVSAIILGKHELFDC
                     AGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNISITEQYL
                     STEK"
     CDS             complement(9958..10053)
                     /locus_tag="ctg1_22"
                     /transl_table=11
                     /translation="MCLSILWGLVHLYLSMADILKEEICHFVYQQ"
     CDS             complement(10001..10177)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: micJ25"
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_23"
                     /sec_met_domain="micJ25 (E-value: 9.7e-27, bitscore: 84.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKHFHFNKLSSGKKNNVPSPAKGVIQIKKQASQLTKGGAGHVPE
                     YFVGIGTPISFYG"
     CDS_motif       complement(10067..10177)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MIKHFHFNKLSSGKKNNVPSPAKGVIQIKKQASQLTK"
                     /locus_tag="ctg1_23_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(10001..10066)
                     /prepeptide="core"
                     /locus_tag="ctg1_23_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="4.10"
                     /molecular_weight="2107.3"
                     /monoisotopic_mass="2106.0"
                     /core_sequence="GGAGHVPEYFVGIGTPISFYG"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MIKHFHFNKLSSGKKNNVPSPAKGVIQIKKQASQLTK"
                     /leader_location="[10066:10177](-)"
     CDS             10518..11144
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_24"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 1.7e-14,
                     bitscore: 45.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 4.7e-24, bitscore: 76.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRYCLTSYREDLVILDIINDSFSIVPDAGSLLKERDKLLKEFPQ
                     LSYFFDSEYHIGSVSRNSDTSFLEERWFLPEPDKTLYKCSLFKRFILLLKVFYYSWNIE
                     KKGMAWIFISNKKENRLYSLNEEHLIRKEISNLSIIFHLNIFKSDCLTYSYALKRILNS
                     RNIDAHLVIGVRTQPFYSHSWVEVGGQVINDAPNMRDKLSVIAEI"
     CDS             11147..12688
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: mcjC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_25"
                     /sec_met_domain="mcjC (E-value: 0.0, bitscore: 1216.2,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.7e-07, bitscore:
                     22.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIFNVKLNDTSIRIIFCKTLSAFRTENTIVMLKGKAVSNGKPVS
                     TEEIARVVEEKGVSEVIENLDGVFCILIYHFNDLLIGKSIQSGPALFYCKKNMDIFVSD
                     KISDIKFLNPDMTFSLNIKMAEHYLSGNRIATQESLITGIYKVNNGEFIKFNNQLKPVL
                     LRDEFSITKKNNSTIDSIIDNIEMMRDNRKIALLFSGGLDSALIFHTLKESGNKFCAYH
                     FFSDESDDSEKCFAKEYCSKYGVDFISVNKNINFNEKLYFNLNPNSPDEIPLIFEQTDE
                     EGEGQPPIDDDLLYLCGHGGDHIFGQNPSELFGIDAYRSHGLMFMHKKIVEFSNLKGKR
                     YKDIIFSNISAFINTSNGCSPAKQEHVSDMKLASAQFFATDYTGKINKLTPFLHKNIIQ
                     HYAGLPVFSLFNQHFDRYPVRYEAFQRFGSDIFWKKTKRSSSQLIFRILSGKKDELVNT
                     IKQSGLIEILGINHIELESILYENTTTRLTMELPYILNLYRLAKFIQLQSIDYKG"
     CDS             12691..14433
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 187.1; E-value:
                     9.3e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_26"
                     /transl_table=11
                     /translation="MERKQKNSLFNYIYSLMDARGKFLFFSMLFITSLSSIIISISPLI
                     LAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLK
                     YLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLS
                     TKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKN
                     NALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVV
                     SIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNME
                     RKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYF
                     GDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEMFKVLKLA
                     NLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINES
                     EILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLA
                     SVTE"
     CDS             complement(14758..15402)
                     /locus_tag="ctg1_27"
                     /transl_table=11
                     /translation="MTSNAPTSFVRAYLRASTAEQDASRAQETIEAFARERGLIICSYY
                     IENESGSRLDRPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNKLKKMIRQKDIRVMA
                     VNVPTTWINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKY
                     KGRKPNQARYDAINRLIESGSSWSQVQKVLGCSRGTISSAIKRKSGLKSSS"
     CDS             15698..16318
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 60.6; E-value: 2.8e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_28"
                     /transl_table=11
                     /translation="MKVISFLNPKGGSGKTTAVINIATALSRSGYNIAVVDTDPQMSLT
                     NWSKAGKAAFDVFTAASEKDVYGIRKDLADYDFAIVDGAGSLSVITSAAVMVSDLVIIP
                     VTPSPLDFSAAGSVVTVLEAQAYSRKVEARFLITRKIEMATMLNVLKESIKDTGVKSFR
                     TAITQRQVYVKSILDGDSVFESSDGAAKGEIEILTKEIVSTFE"
     CDS             16370..16600
                     /locus_tag="ctg1_29"
                     /transl_table=11
                     /translation="MSLEKAHTAVKKMTFGENRDLERVVTAPVSSGKIKRVNVNFDEEK
                     HTRFKAACAKKGTSITDVVNQLVDEWLKENE"
     CDS             16616..16927
                     /locus_tag="ctg1_30"
                     /transl_table=11
                     /translation="MDKNVVDALKTLLEALREEVVTEVTSKLNPSASHIPEENSKQMTA
                     KARLLNFRLTEAYEEILEAEAIRTGQSKTTVLKAALAAFDSLDENRKNHWLLESAKLG"
     CDS             17114..17338
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) darobactin_precursor"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_31"
                     /sec_met_domain="darobactin_precursor (E-value: 1.0,
                     bitscore: 7.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIFIVLAGLLLGCCNLFDNYRSYKKGVYKEHRKMAPPVYYYRGD
                     HTFVIRIVIDSLLSLVIIGFVVWLWFKTA"
     CDS             17362..17661
                     /locus_tag="ctg1_32"
                     /transl_table=11
                     /translation="MASDNRYSINFTLSVLEKTEASKLIKEHEKQEHIEPYGYILLIKK
                     AALLVLSFAALFDFIILFGLIALAPKDPDYVERAKFLSIITFTLIAISIGLLYI"
     CDS             17974..18834
                     /locus_tag="ctg1_33"
                     /transl_table=11
                     /translation="MINIENTIKFMMKDIDKYLDDITLNAITVDSKTILKLEDMSSKNI
                     SPYLKKILGTLIKIEVEHIPDFDFSKIQSLENSKSFKHLPAKSKNPSCYRDLYSWGKEM
                     PHTEKLKAEDESDWKKNIQHIEKEEFLRNRPIEITYYTWLDRYFVSNSGGSHHAALVVW
                     QSVRDKLEYKREANITKLSIDKDSIKKLNSDYWSFILKFRYQTNINTLFNLFNSLVSKH
                     TDMLEPSHYHGNYRLFFVPKSQLKMNKYAFEYWYRNSVKNKKIIALPEYLENPLQFHTG
                     GILIQ"
     CDS             complement(18856..19212)
                     /locus_tag="ctg1_34"
                     /transl_table=11
                     /translation="MKYQVKEFITDKYAKAVNILKDNVKEHYHVFYGIRLSEILFPASE
                     YGSEQFFSDFEKINSISLPVLVFDLKTGVPVIVISLDDISYCDVLERTDIDFVKYDSLA
                     ELLTSEKLDALFKD"
     CDS             complement(19349..19795)
                     /locus_tag="ctg1_35"
                     /transl_table=11
                     /translation="MAKIYQFPQGEERAKFRKEIARERKKRFAVKTGSTFVKWLDWGWF
                     YLRLLAASILHFIFVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWILGLLAEPLMELLNKTMPWHKLLVPEPADESTENSSEVSQK"
     CDS             complement(19835..20671)
                     /locus_tag="ctg1_36"
                     /transl_table=11
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGAEELQASVIRIPRNQLLTAQGNQISGH
                     TKKRGKLPSDAVRLMNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIVERVARRASKLRFSYKIDKESEGLDIRIPYGFRG"
     CDS             complement(21681..21812)
                     /locus_tag="ctg1_37"
                     /transl_table=11
                     /translation="MALSDIALKRSVTRSERFSRFVVVGYGLTVFNAAQRFLVALLL"
     CDS             21904..22155
                     /locus_tag="ctg1_38"
                     /transl_table=11
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVVDERMKNPEIVKVNLDDL"
     CDS             22145..22426
                     /locus_tag="ctg1_39"
                     /transl_table=11
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPSARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADLR"
ORIGIN
        1 tatttgctcg tgaggttgat tttgagcagt tgctcgaaat gcaggaaaag ctcaaagctg
       61 ttattgaaga acgtcgtgaa gatgctgaac gtgaagcggc tgaacgggct gagcgtgaac
      121 ggaaacgtca ggaactgctt cagttaattg ccggagaggg tttctcaccg gaagaactgc
      181 ttggtctgtc cgaagaagca ccaaaatcac gtaaaaaaac gttaccaaaa gcgccaccca
      241 agtatcagtt tgaagaaaat ggtgaaacga aatactggtc tggtcgtggg cgtgcgccaa
      301 aaccgatagc tgaagcactg gcaggcggtc gctctcttga tgagtttatc atcaaaaaag
      361 atgcttccag ctctgctggc gacgaacagt aatataatag gcttctggtt tacgcaggag
      421 acttttttga taaacaggag gatgttttga gtctgacatt accattaatg tatttccaga
      481 caggtgcaga tctcagcaaa atcacacatc atgaagtgca ctatcaggac ggctttgttc
      541 agcaggcatg gttgcaacct gaaatacagc tatttgttgt gtgtatcgcc aggaaaaaag
      601 gctcccgtcg cgagattaaa ggtggaatgg ccgttctgac cagtattccg gccagcaatg
      661 gagcggagtt ggcaaaagcg ttggataacg ttatgcgcca gtctgatgag ttgcggccac
      721 tggcagggaa agacgaaaac gtatttatcc cagccagaat tggaatttct ggcgaagaac
      781 cgccaacaga gcaagagctt ctaagtgtct tttaccagca atgtctgaaa catggctcat
      841 ggggcagtgc ctgatttctg gtacataaag cagggatacc ccctgcttac ctttcttgcc
      901 agcaatatta cgcgctcgat gctcttcctg ggcttgatat tgccagggta tagcgtcagc
      961 acaacccgga gcacgcagat tcgggtgtga ttctgattta ggacgggaag gtgtattgct
     1021 ggaaaaatat tctccgcgcc cctcagcatg agcgccccag agtgatagcg gtagatactg
     1081 aagagaacgt gtttattgca gaaagtagca atgaatatga cggcgcgaaa tgctgggttg
     1141 tcgatgatga cgatagccac agaacgcgct acagcgagct acaacaggcg tttgatttct
     1201 ataaccagcg cctttttgac ggtgaactcc ccgagtgtct gattacgttc cagcgcgtca
     1261 cactggaact gtttcagggt aaatttgctt tgagctggtt tgatcgcttc cctgtccagg
     1321 ttgaacaaca aaaagagatg gccgccgtca tcgatcaatg gcgggaaact acttgctcaa
     1381 gcacatcaaa atgctgaacc gggattgata ttgaagccgg tgctgtcagt gtcaccgtag
     1441 aacgggagca atgataacga tctgtttgtt gcggcttttg aggacaagcc aaaaaggaac
     1501 aaagtcaaat atcagtgtcg gggtgtggtg ctgctgtctg gggaagtccg gagtgaatat
     1561 tgaatgcggt gattgcgagc tgcctttcat cgaaaattaa tctccatttt cgtggcattt
     1621 cctgattctt tctcataaat tctcgtgtcc aatccgaccc gaaaaacctc agatttcacg
     1681 tagcgcacca ccgctcattg agtggcttct caacgtgact ggtaatcagg attattggtt
     1741 tctaatgtaa tgaacgatgg atgtatcaaa tttttattac aaaatggttt aaacgtagat
     1801 gattatattc tgtatggttg tttatgtcta aatatataaa ttaataaatt ttagaataaa
     1861 aatgtataac cgcaaataat atgattgtgc tgttcttttt ttgtgaaatg aatctatgtt
     1921 tgtatatttt catgaggaat attgtttttt atagtgataa aaacacttgt gaattaatca
     1981 cagtaatagg aggcgtagaa tgcgtactgg taatgcaaac taatggcaaa atataaatgt
     2041 ccattaaatg ccaccctgta cagggtggca tacaaaattt atctgcgagg tttatttatg
     2101 gattatatat tgggtcgcta tgtcaaaatt gctcgatacg ggagcggtgg attagttggt
     2161 ggaggcggaa aggagcaata tgttgaggat ttagcgctct gggaaaatat tataaaaacc
     2221 gcatattgtt tcataacccc atcgagttat actgcagcgt tggaaactgt caatatacct
     2281 gaaaaagatt tctctaattg ctttaggttc cttaaggaaa atttctttat tatacctagt
     2341 gagtataata actctactga gaataatcgt tactctcgta actttttaca ttatcaaagt
     2401 tatggtgcta accctgttct tgtgcaagat aaactaaaag atgctaaggt agtaattctt
     2461 ggttgtgggg gtataggaaa tcatgtatct gttatactcg caacgtctgg tattggcgaa
     2521 attatactaa ttgataatga tcaaatagaa aatacaaatt tgacaaggca ggttttattt
     2581 tcagagaatg atgtcggtaa aaataaaaca gaagttataa aacgcgagtt attaaaaaga
     2641 aactctgaaa tttcggtgtc tgaaatcgct ttgaatataa acgattacac tgatcttcat
     2701 aaggtaccag aagctgatat atgggttgtt tctgcagatc atccatttaa tctgatcaac
     2761 tgggttaata aatattgcgt tagagcaaat cagccctata taaatgctgg gtatgttaat
     2821 gatattgcag tctttggtcc attatatgtt cctggtaaaa caggatgtta tgagtgccaa
     2881 aaagtcgtgg cagatctata tggttcagaa aaggaaaaca ttgatcataa gattaagcta
     2941 atcaatagca gatttaaacc agcaacattt gcacctgtga ataatgttgc cgctgcatta
     3001 tgtgcggcag acgtaattaa gttcattgga aaatactccg agccattatc acttaataaa
     3061 agaataggca tctggtcaga tgaaataaaa atacattccc aaaatatggg ccgttcgcct
     3121 gtttgctctg tgtgtggaaa tagaatgtga atactgcaaa tattttatct gtgaactatg
     3181 gagcttataa tgctatacgt atgttaattg gtgtctacca tgcagcattt cttatatcta
     3241 caggtgtcac tatatctcaa cttgctgttt tacaaatcat tttttctgtg acagtgctga
     3301 ttcttgattt tcctttatct gtcattgcag acagatttta caggaaacag gttgtagtta
     3361 gtggcgtatt ttttactatt ttattttacc ctctttgtat tcagtctcct gatatgctgg
     3421 cattggtttt ttctgaaata ttttatgcca ttggtatttg ttgtatatct ggggctatag
     3481 agggatgggt gttaagtgct ctggatggta gaaatgaaaa atttacctta tgtgctcatt
     3541 tatgcgaaag ggtatcttcc tttgggagtg tgataactgg tgctgttgga atattagttg
     3601 tctacttcta tgattcttat aaatctggct atatagtatc gttcttcttg atgtttgttg
     3661 tctttatcgt ttttttatgt gtaaaaacta acggcagtgg gggtgaaaaa gaagcacgag
     3721 atagtattat taaacaagca aaagagagta ttggattgat aacaggaagt tataatggga
     3781 catatttttt atctataaca tgtatgttta cacttggtat acaggtaatt tatcattttt
     3841 ggcagccaat tatgttatct ggggaaagta ttggctcatt atcaaaaaga gagcttataa
     3901 ctttactgat gtgtcatatt ggtgcatttt caatgcaata tatagcaaac tatcttatgc
     3961 caaagataga tgtaagatgt aaactttata tacttgtttg tacattatgt tcatttctta
     4021 gttcaatcgc ctgtatttta ctatttattt taataacaga taataatgtt gttctcggtg
     4081 tagctatttt ctctataatc catgggatga tttcaacaat acctgttgga gcacagaata
     4141 tattcataag cagacttaat gacaattata agaatattat ttcgggagct cttggtattg
     4201 tttctctttc atgtcgtgtt gcttccattt ctgtgttggg agttatatct gtattaccag
     4261 gtaatatgcc tgtcaccact tatatattta tctctgcaat tgcatgtgta ctgtgtggtt
     4321 gtttgttctt aatgtggtcc tttaaaaagg agatggtatg acgattaaac atgctgaaga
     4381 attgacggaa gaagtcattt taaatatgaa ttaccctgat tttgttgctc tgatgcaaca
     4441 ggataacact cctcctggag cagagtacac catagactac tggattaagc atggatgtat
     4501 taacaaaaag tctcacctat tagatttagc atgttccacg ggttttagtt cacgtgaatg
     4561 cttcaaaaaa gaaggtgcat ctgcagaggg tattgatata tctgaatcag ctgtaatggt
     4621 cgcaaatgaa aaggcaaaaa agcttaaggc taataattta ttgaaatatt atgtagctga
     4681 tgcttgtgat ttaccatttg aagataactc ttttacacat gttctcggtg gatgtaattt
     4741 tgcatttata caaaatcggt taatagcttt gaatgaaact catcgatgtt taaaccacat
     4801 gggaagcatg tgcatttcaa atttttatta caggcgtaaa atatcagata aacttatcaa
     4861 tgatgtatat aatgcaataa atttcagacc caatcctttg tggactttgg aatactggca
     4921 tcagtttttt tctgaaagat ttactctggt ttcagaagaa aatcatgaga tggaatctca
     4981 aagtgaagat gagttaaaag ccgatattta tgattacatt ttcaatagaa atgagtttac
     5041 aaaaggtttg aatggttcac ttcagaatgt attttttgaa agatttttaa aaatacgcag
     5101 accattaaat atccaaagag attatcaggg agttacattg caaatatggc gcaaaaaata
     5161 acaccatcta aaattgttaa acatgcccgg gagttaatta ttaaggggat tgaatcgggc
     5221 gataactcat ttgtcatttt tgatgtagat ggagctctgg agcgtctgga acattacagg
     5281 tgtcaactta agagtttttt ccccaacagc agtatcgcat attcatataa gtcaaataat
     5341 ctggcacaat ggtgccagat tatctcaggt aaaggtttgt atgcagaggt gtgctctgtt
     5401 gatgaaatga acctcgctaa aagagacggt tttaaccgga ttgtttttga tggcccttta
     5461 aaaaaaacga gtgaactatt aaaggcaata gagattgggg cattaattga agttgacaat
     5521 attgatgaat gtaaaagact taatgaacta tgtaaattgc ataagttgac atgtagaatt
     5581 catttgagat tatcgcatta ctatgatgat aatttatcaa gatttggctt atctgaaagt
     5641 gaggctatta atttactgga gatgttgatc agtaagtcag agtatctcat tttagacggg
     5701 ttccatttac atgttggctc taatctaccc aatgcggaaa aaatatgtaa agctattata
     5761 cagtatcatg agttgattct taggtatatg ccagatgatg gcactcttaa tcttggtagt
     5821 gggatacctg cagattcttt ctcagcatcc agtgataacc caactccatg tccggaggta
     5881 tttttctcat cgatatatga tacaataaaa aattgcttcg gtactgtatg tgataaatgg
     5941 aactatattt ttgaaccagg gagacatctg gtcgaagact ttggctactt tatagggaaa
     6001 gttattagta ctaaaaacag gtatggtgtt aaagttgctc aaactaacat tggtataaac
     6061 tggatacctt cgatcagaaa ttgggaccat tcatttacat tgtttcataa tcataaccat
     6121 atttcagatg ataaatctga tgagtatatt attgctggat tcaattgctt tgaatgtgat
     6181 tgcttgtttc cttcagttat tcttcccagt aacttatctg agtatttatt ttctgttcga
     6241 gggtgtggtg cttatgatat gcaaacagga aaccagtgga cgcgtaatct ttatgctgta
     6301 tataccataa caaatgatgt tgttaatata tcaaggattc acagaagaga acttgatttc
     6361 cggaagtatg atgtatctct tacgccatca ggaataaaag taaatgatga gattacattg
     6421 ttgtatccag cgttaaaata cgctgaagag ttatatttgc tcattaatca aaacaaaata
     6481 aatttcatta aaagcatggc atggccagcg tttgttaata acatttctga ttctgtttct
     6541 ttcattgagc aatcaatgat tgataaccag aatgaaaaag cattaatcct ctttattaaa
     6601 tacaaaacta agatagctgg cgttgtatct tttaatatta ttgaccatgc caataaaaca
     6661 gcatatattg gctattggtt aggcgctaac tttcagggaa aggggattgt aaccaatgct
     6721 ataaataaac tgatacagga atatggggat tctgacgtta taaaaagatt tgttataaaa
     6781 tgtattgttg ataataaaaa aagtaatgcc acggcattga ggtgtggctt caccttagaa
     6841 ggtgttctgc aaaaagcaga aatactcaac ggtgtatcat acgatcaaaa tatttattcg
     6901 aaagtaattg gttaatactg tatggcgtag tattctacgc cattttgttt atgtctgtga
     6961 gatgataata tttatttctc ggtagataga tattgttctg ttatagatat atttttgttg
     7021 tcaaagtcaa tggctaattt tacaccaagt ggaagagtta gcattggatg tgtatgtgaa
     7081 caatcaaatc catccagtac aggaatctgt ttcccatcta atacctctgt taatacttca
     7141 tatggtctgc gtttacttcc tgcacaatca aaaagctcat gtttcccgag tattattgca
     7201 ctaactttat caaacacgcg attaagcttt agcatagaga ataatcgttc aactgttgca
     7261 atgcttttcc gactgtcctc aataaacaat atatctccat tccgaatttc aggcatccat
     7321 tcactccccc atatacctgt caaagtattt agatttcctc caattacacg cccctcaact
     7381 tttccggaac cataaaaggc acagttgttt ttatatagtt tcttaggcct taatatcttg
     7441 ttttcattcc agtttatgct ctcatcactc cacttttcag gtaatgtgta ggtatatatt
     7501 cctgattgtt ttcttgttag tattttaata aatgattcat atgttatatc cacaagaggt
     7561 ggatgttcac caaacgaagg aataagagct ggtccataga atgttattaa ccctgttttt
     7621 gcatatattc ctgctaataa agcagttgta tctgagtaac ctatgataat tttggggttt
     7681 gcaatgatag catcatagtc cagaaacggt agtagtgaat tactgttatc tccaccgatc
     7741 gttgacatta tacaggtaat atcaggattg tagactaact cattaaattc ttgagctctt
     7801 tctttaatag tacctgaacg ataaaaatct gttttaccgg taagcttccc tgataccagc
     7861 ttaaatccct ttctctgaag aaactcaact ccccgaaaaa aacgattttt tgcagtaact
     7921 gttgccggag cagatgatga aaagaaacca attgtatctc ctactgccag gggagcggcc
     7981 agtagcggat gagattgtat catcatgagg atttttcctt tccatttagt gtcaaaatga
     8041 acccgttttg agatatgtca gtagcacttt cagtttatgg gctttttttg aaaatcgcag
     8101 tgttctctcg taaattttct cgcccaatcc cccccgaaaa gcctcagagt tcacgtagcg
     8161 caccgccact actgtatcca tcaaaaaaac tgatagcttt tttaatcatc tgttgtgctg
     8221 caacttactg aaaaaaatgg attcatgaaa acaccgataa cggcattgat ctgttggcca
     8281 acgcgatcag cagtattggc cgcaacaaaa aatgaaagaa acatccctca aatgaagggg
     8341 aaaaaacgga agtacagccg aacgacaggc acaaaaaaac ccgactggta atcgggcttt
     8401 tttgtgtttt ccagccctga gttggtggct ctgactggag aaggttactc tacacctaac
     8461 gtttacattt tattcactat ggtgctgtaa agcaactaaa tgtggttaag gaaccacatt
     8521 tagtggtgta acgggtgttt tgtgtagcgt ataatcagtc agttagtcat gtagttgact
     8581 tgcaatcctg ctcttcccgt atctgcgggt atgaacgatt ttaaagtcct ggctggataa
     8641 acaggtggtg ctgtattcgg tgctctggca ggaggaggtc actctacacc taacaatgcg
     8701 agagagccgt tgtgacaggc agtgtatgag taagcaacgg tgatttcctc cagttttact
     8761 ggagaaacgg atgattaatt tgttaatcat cgttctcagg gctgtggtcg ccgttgcaaa
     8821 cgcgctgatt gcaattctgg aactgattcg ccagttcatc gactgatgac agcggaaacg
     8881 taactaaggg caggaagtga accgcttcct gccctttaac gtactgtgac atttttcaaa
     8941 aaaaaatcac caatattctc ctcggcagaa atgacataac ttactgtgaa ataaaaaatt
     9001 atctaaacac tggctttgca tcgagcgcgt tggccaacgc ctttatcagt tgcgaccgca
     9061 ccagataatt tgaacaagat ttcccgcata acctggacat acagattatt ctgtccagat
     9121 tttattagtt acaacataca atgaatttat ttcctttatc tggtgctctg ctccggcata
     9181 cgcgcccata tcctaggtaa ttcaggataa cagccagatt tcgtcctgcc gttcatatcc
     9241 gcctggacaa aaatgcatta tcggaaaaaa tgtccaaaat ttttttggtg atcggaattt
     9301 ttgttgtcgg acgcacctct tcttcaggtc ataattgctg acacatccca aaaaacagga
     9361 gcggagattt aaaaattgag tcacttaccc gccaaaattt tccagatttc acgtagcgta
     9421 ccgtcgatac tgtatccatc aacaaatgac tattttttga atgtgtcatt tcctgtaacc
     9481 tactgaaaaa tatcagtgaa tgacaatatc ggcgacagca tcggagctga tagccagttt
     9541 cctgaatgca tatggccaga acagtaaatt tgaaccaggt tctcacgtca ccaggcgacg
     9601 tgtctgggaa actggtgaac aacaggcaca gaaaagccca actttatggg ggtcagttca
     9661 gtgaggttga gctaagagaa acgaatgatt aacctgttaa tcatcattct cagggatgtg
     9721 gtcgccgttg caaacgcgcg gattgcagtt ctggaactga ttcgccagtt catcgtttga
     9781 tgacagcgga aacgtaactc aggacaggaa gttccaaata gctcccagcc agcatatgta
     9841 attttcaaag gggcagttgt taactctgta ataacgccat gtaaagtatt cctgccccct
     9901 ccatgatcct ccatagtatt tcttgagtta attttcaaaa agcttctgat atgtgattta
     9961 ttgttgatag acaaaatgac agatttcttc tttcagaata tcagccatag aaagatatag
    10021 gtgtaccaat ccccacaaaa tactcaggca catgtcctgc accacctttt gtgagttgcg
    10081 atgcttgttt ttttatttgt ataaccccct ttgcaggaga tggaacatta ttttttttac
    10141 cagaagacag tttattaaaa tgaaaatgct taatcatttt tacgttcctt atttgatgaa
    10201 aatagtatga tgatttttac agaggaacct cacgtccttc tgttagaatt ttattagcac
    10261 aaaatacaat tgagatcaat aatcattacg ttttattaat ttatcaataa aatcatttag
    10321 atacaaacat ccataaacta atcaatctgc aaaagtggtc aaatttagta caacattttg
    10381 gatttttata catttttcta attatttcag aatatttagc catcaattaa gaaaaaaaat
    10441 ttagcttgta gataaattca gaagttttat tattctaatt gagtgtaaag gcataactac
    10501 aggagggagt gtgcaaaatg atccgttact gcttaaccag ttatagagag gatcttgtta
    10561 tcctggatat aattaatgat agtttcagca tagtgcctga cgcaggtagc ttgctaaaag
    10621 aaagagataa attgcttaaa gaattcccac aactatctta cttttttgac agtgaatatc
    10681 atattggaag tgtttctcgt aatagtgaca cttcttttct tgaagaacgc tggtttctac
    10741 cagaacctga caaaacatta tataagtgtt ctctatttaa acgatttata ttattactca
    10801 aagtctttta ctatagctgg aatattgaaa aaaaagggat ggcatggatt ttcataagta
    10861 ataaaaaaga gaataggcta tactccttga atgaagagca tcttatccgg aaagaaatta
    10921 gtaatctttc cattatcttt catcttaata tttttaaatc tgactgtctt acctattcat
    10981 acgcactaaa aagaattctt aattccagaa atattgatgc tcatcttgtt attggtgtaa
    11041 ggacacaacc tttttatagc cactcttggg tggaggttgg gggacaagtt atcaatgatg
    11101 ctcccaatat gcgggataaa ttatctgtta ttgcagagat atagttatgg aaatatttaa
    11161 tgtcaagtta aatgatactt caattagaat tattttctgt aaaacgcttt ctgccttccg
    11221 gacagaaaat accatcgtta tgctcaaagg aaaagcagtt tcaaatggca aacctgtatc
    11281 cacagaggag attgccagag tagtggaaga aaaaggtgtt tcagaagtaa tagaaaattt
    11341 agatggtgtt ttctgtatcc taatttatca ttttaatgat ctccttatag ggaaaagcat
    11401 tcaatcaggc cccgctctat tttattgtaa aaagaatatg gatatttttg tttcggataa
    11461 aatttctgat atcaaatttt tgaatccaga tatgacattc agtctaaata taaaaatggc
    11521 agaacattat ctgtcaggaa atcgaatagc aacccaggaa tcactaatca ctggcattta
    11581 caaagtaaat aatggtgagt ttataaaatt taataatcag ttgaaacctg tgctacttcg
    11641 tgatgagttt agtattacca aaaagaacaa ttcaactatc gacagtatca ttgataatat
    11701 tgagatgatg cgggataata gaaaaatagc cctattattc tccggaggat tggattctgc
    11761 attaattttt cacacactta aagaatcagg taacaaattc tgcgcttatc attttttttc
    11821 tgatgaatct gatgacagtg aaaagtgttt tgctaaggaa tactgttcaa aatatggagt
    11881 tgactttata tctgttaata aaaacatcaa ctttaatgaa aaactttatt tcaatttaaa
    11941 tcctaatagt ccggacgaaa tccctttgat atttgaacag acagatgaag aaggtgaagg
    12001 tcagcccccc atagacgatg atttattata tctatgtggt cacggtggag atcatatttt
    12061 cggacaaaat ccttcagaac tttttggcat tgatgcatat cgaagtcatg gcttgatgtt
    12121 tatgcataaa aaaatagtag aattttccaa tctcaaggga aagagatata aagatatcat
    12181 attttcaaat atttccgcat tcattaatac atccaacgga tgttctccag caaagcaaga
    12241 gcacgtatca gatatgaaac ttgcctctgc tcagtttttt gcaactgatt atacaggaaa
    12301 aattaataaa ctaactccat tcctgcataa aaatattatc cagcattatg ctggcttacc
    12361 agtttttagt ctatttaacc agcactttga tcgttatccc gttcgttatg aagcgtttca
    12421 acgatttggt tcagatattt tctggaaaaa aaccaaacgg tcatcttcac agctaatatt
    12481 cagaattcta tccggtaaaa aggatgaact agtgaataca ataaaacagt caggattaat
    12541 tgaaatatta ggcattaacc atattgaatt agaaagcatt ttgtatgaaa atacgactac
    12601 acgtctgaca atggaactac catatatact taacttatac cgtctggcaa aattcattca
    12661 acttcaatcc attgattata aaggttaatt atggaaagaa aacagaaaaa ctcattattt
    12721 aattatattt attcattaat ggatgcaaga ggtaaatttt tattcttttc catgttattc
    12781 attacatcat tatcatcgat aatcatatct atttcaccat tgattcttgc aaagattaca
    12841 gatttactgt ctggctcatt gtcaaatttt agttatgaat atctggtttt acttgcctgt
    12901 ttatacatgt tttgcgttat atctaataaa gcaagtgttt ttttatttat gatactgcaa
    12961 agtagtctac gtattaacat gcagaaaaaa atgtcgctaa aatatttgag agaattgtat
    13021 aacgaaaata taactaactt gagtaaaaat aatgctggat atacaacgca aagtcttaac
    13081 caagcttcaa atgacattta tattcttgtg agaaatgttt cccaaaatat cctgtcacct
    13141 gttatacaac ttatttctac tattgttgtt gttttatcta cgaaggactg gttttctgcc
    13201 ggtgtgtttt ttctctatat tctggtattt gtaattttta ataccagact gactggcagt
    13261 ttagcgtcac tcagaaaaca cagcatggat atcactctta actcttatag tctgttatct
    13321 gatactgttg ataacatgat agcagctaaa aagaataatg cattaagact tatttctgaa
    13381 cgttatgaag atgctctcac tcaggaaaac aatgctcaga aaaaatactg gttactcagc
    13441 tctaaagttc ttttattgaa ctctttactt gctgtaatat tatttggttc tgtattcata
    13501 tataatattt taggtgtgct gaatggtgta gttagtatcg gccacttcat tatgattaca
    13561 tcatatatca ttcttctttc aacgccagtg gaaaatatag gggcattgct aagtgagatc
    13621 aggcagtcaa tgtctagcct ggcaggtttt attcaacgtc atgccgagaa taaagccaca
    13681 tctccttcaa taccttttct caacatggag cgaaaattaa acctgtccat aagagagctt
    13741 tcatttagct atagtgatga taaaaaaata cttaattcag tcagtcttga cctttttact
    13801 ggaaaaatgt attcattaac cggacccagt ggttcaggaa aatccaccct tgtaaaaata
    13861 atatcaggtt actataaaaa ttactttgga gacatttatc tgaatgatat atccttacgt
    13921 aatatcagtg atgaggattt gaatgatgct atttactacc taacacaaga tgattatatt
    13981 tttatggata cactacgatt taatctccgg ctcgcaaatt acgacgcgtc agaaaatgaa
    14041 atgtttaaag ttcttaaact ggcaaatctt tctgtcgtca acaatgaacc agtgagtctg
    14101 gatacacacc ttataaacag aggcaataac tattcaggag ggcaaaaaca acgaatttcg
    14161 ttagcgcgac tgtttttgag aaaacctgca ataattatta ttgatgaagc cacatcggct
    14221 ctggattata ttaatgaatc agaaatttta tcatcaataa gaactcattt tcctgatgcg
    14281 ctaattataa atattagtca ccgaataaat cttctggagt gttccgattg tgtttatgta
    14341 ttgaatgaag gaaatattgt tgcttctggc catttcaggg atttgatggt cagcaatgaa
    14401 tacatatcgg gactggcttc tgttactgaa taaaatatct gactcctgct ctgtattcag
    14461 aaagggagtc gcttggaaaa cggaattttt cccacgttaa gagaattggg ttgcacgagt
    14521 ggttacatcc cggcaagcta agccccagaa tgtaagggtt gttcgaaatg ctctgaccgt
    14581 ccgttaatcg tttagcttac ttcttccgca catccccttg cgtaaatgta cagaattgta
    14641 cggtttcaga cacaaaaacc gctgtaaccc cgcagttcag gtgccccaaa aacaatttga
    14701 ttaaaaaata atcttaacgg gggttgtttt ccgaacttcc gacatctcct cccttctcta
    14761 actactggat ttcagcccgg atttacgttt tattgcgcta ctgattgtgc cacggctgca
    14821 ccctagcact ttctgaactt gactccagga gcttccgctc tcaatcaacc tgttaattgc
    14881 gtcatatctg gcttgattag gtttacgacc tttatatttg ccgtctttcc ttgctttctc
    14941 tatcccttgt ttctggcgtt cccgtcgttg ttcatagtcc cttctggcaa cagcggccag
    15001 catatccagc agcatatcgt taatggcagc aaacaaccgg ctgtcaaact cactcatgcc
    15061 agaattaatc catgtggtcg gaacgttcac ggccataacc cggatatctt tctgacggat
    15121 cattttcttc agcttattcc agtcttcccc tgacaggcgg gaaagtctgt caacgtcctc
    15181 aatgagcaaa atgtcatttt gctggcaatc tctcagaaga cggaagagtt caggacgatc
    15241 gagacgagaa ccggattcat tttcaatata gtagctacaa atgatcaagc ctctttctct
    15301 ggcaaaagct tcgatggttt cctgggcacg cgaagcatcc tgttcagctg ttgaagctct
    15361 cagataagcg cggacaaagc ttgttggtgc atttgaagtc atattacaga accagttcgc
    15421 ataaggtcac accactatac ccaaaatgca ccagaaagtg gatcgacagg aaaggcacac
    15481 tctaaaagaa ccaaaacaca aataatgagt agatgtgacc ttgtcaccat atactcataa
    15541 actcaaatac tcacacacac aacacaaact caaatgagta aacactcttt aactcatata
    15601 cacatagact catattaacc tttactcatg caaagagtat ggtaaactca aaaactcaca
    15661 ggagtaattg agtagataca caattgaggt tttgagtatg aaagtaatct catttctgaa
    15721 tcctaaaggg ggttcaggca aaacaactgc cgtaatcaac atagccactg cgttgagcag
    15781 gagcggatac aacattgctg tggtagacac agatccacaa atgagcctga cgaactggag
    15841 caaagcaggc aaggcagcat ttgacgtatt tacagcagca tctgaaaaag acgtctatgg
    15901 aatccgaaaa gatctggcgg actatgattt tgctattgtg gacggagcag gttcgctctc
    15961 agtaatcacc tccgcagccg tcatggtaag cgatctggta ataatccctg tcacccccag
    16021 ccccctggat ttctccgcag caggaagcgt cgttactgtt ctggaagcac aggcttacag
    16081 ccgcaaagtt gaagcccgct ttctgatcac ccgtaagata gaaatggcaa ccatgctcaa
    16141 tgtgctgaaa gaaagtatca aagacaccgg tgttaaatcc ttccgtacgg ccattacaca
    16201 acgtcaggtt tacgtgaaat caattctgga tggtgacagc gtgtttgaat ccagtgatgg
    16261 tgcagcaaaa ggtgaaatag aaatccttac aaaagagata gttagcacat ttgagtaatt
    16321 acacatttac tcatataatc aaataagtat aacaaccgga gaaagcttaa tgtcacttga
    16381 aaaagcgcat acggcagtaa aaaaaatgac ctttggtgaa aacagagatc tggaacgagt
    16441 agtaacagca ccagtatcat caggaaaaat caaacgtgtt aacgtcaatt ttgacgaaga
    16501 aaaacacacc cggtttaagg ctgcatgtgc caaaaaaggt acatcgatca ctgatgtggt
    16561 gaaccagctt gtagatgaat ggctcaaaga gaacgaataa tatctgagga atatcatgga
    16621 taaaaacgtc gttgatgcgc tgaaaacgct attagaagcg ttacgggaag aagtggtaac
    16681 agaagtcaca tcaaaactaa atccttcggc aagccatatt cctgaagaaa acagtaaaca
    16741 aatgacagca aaagcaagac tactgaattt ccggctaacc gaagcctatg aagaaatcct
    16801 ggaagctgaa gctatcagga ctggtcagag caaaacaacc gttctcaaag cggcgctggc
    16861 cgctttcgat agcctggacg agaaccggaa aaaccactgg ctgcttgaat ctgcaaagtt
    16921 aggttagcat tatggctaag aatgatagat atgttgttat ggttgggaat aaaaccatat
    16981 acagcggtaa tcagcgattt ttagcctggt tagtatggtt agctcacagg tacaataaag
    17041 ccattgcctg tgacaacggg atatggattg tcgagccatc ttactggttg aggactggaa
    17101 aggaaaaatg ataatgagaa tattcattgt attagctggt cttctcttgg gatgttgtaa
    17161 cttatttgat aactacagat cctataaaaa aggagtttat aaagagcatc gcaagatggc
    17221 tcctcctgtt tattattatc ggggagatca tacttttgtc atacggatag taattgattc
    17281 acttttaagt ctggtgatta ttggctttgt tgtctggtta tggtttaaaa ctgcttaaca
    17341 tcataacatc gaggaagcaa aatggcatca gataatagat acagtattaa cttcacgcta
    17401 tctgttttag aaaaaacaga agcaagcaag ctgataaaag aacatgaaaa acaagagcat
    17461 atagaaccat atggctatat attgcttata aaaaaagcag cgttgttagt tctttcattt
    17521 gctgcattat ttgattttat aatacttttt ggtttgattg ctctcgcccc aaaagaccct
    17581 gattatgtag aaagagcaaa atttctttcc attattacat ttacactaat agctatatcc
    17641 atcggtttgt tatatatata attatttaat gaaaaatgtg atgaggagta actactcatc
    17701 agaaataaga gacccggaac taatattacg tctaaagata aatcgttcat acattgaaca
    17761 aataatgaaa attggtagtt cgagggtttt ctggaataac ataaaaaaga cataccgaaa
    17821 gcaaggattt ctgtttatcc agacaaaaga aaacagatgc atcatcattc cagaaagagt
    17881 ttttaaaaat gaagaagaaa ctgaaaaatt atatagcttt gtaaaagagc aaatagcaca
    17941 gaacactatg gaatgaaaaa ggaatattaa gtaatgataa atatagaaaa cactatcaaa
    18001 tttatgatga aagacattga taaatatctg gatgatatca ctctgaacgc catcacagtg
    18061 gatagcaaaa ctatattgaa acttgaggat atgtccagta aaaacatatc accttacctt
    18121 aaaaagatac tcggaacgct tataaaaatc gaagttgaac acatacctga ctttgatttc
    18181 agtaagatcc agtctcttga aaactccaag agtttcaaac atcttccagc taaaagtaaa
    18241 aaccccagtt gctacagaga cctgtattcg tggggaaagg aaatgcctca cacagaaaaa
    18301 cttaaggcag aagatgagtc cgactggaaa aagaatattc aacatataga aaaagaagaa
    18361 ttccttcgta acaggccaat tgaaataaca tactacacat ggcttgacag gtattttgta
    18421 tcaaatagtg gaggttctca tcacgcagcc cttgttgtct ggcaatcagt tcgggacaaa
    18481 cttgagtaca aaagagaagc caatataact aaactcagca ttgataaaga ctccataaaa
    18541 aaactgaata gtgattactg gtcttttata ctaaaattca gatatcaaac caacataaat
    18601 acattattta atctgttcaa tagcctggtc agcaagcata cagacatgct ggaaccaagc
    18661 cattatcatg gcaattacag attgtttttt gtccctaaaa gccagctaaa gatgaacaag
    18721 tatgcttttg aatactggta cagaaattcg gttaaaaata aaaagataat tgcgctacct
    18781 gagtacttag aaaaccctct tcagttccat accggaggca ttctcatcca gtagacagag
    18841 aagggggcat aagagtcaat ccttaaataa cgcatccagc ttctcgctgg taagcaattc
    18901 tgccagcgaa tcatatttca caaaatcaat atctgttcgt tccagaacgt cacaataact
    18961 gatatcatca aggctaatga caatcacagg aacaccggtt ttgagatcaa acaccaggac
    19021 aggtaatgaa atcgagttta tcttttcaaa atcactaaaa aattgttcag agccatactc
    19081 actggcagga aaaagaatct cacttaatct aataccataa aaaacatggt agtgttcttt
    19141 aacattatct tttaaaatat taacagcctt cgcatattta tcagtaataa attctttcac
    19201 ctgatatttc ataaaacact ccaacaagaa ccgactgtag gtcaccgggc aaacgttgcg
    19261 gaatggcgtc agagacgtca tttagcggcg tttgccctat cctgcatcgc agtgaaaagg
    19321 cagggactgg cataactgct gagtagcatc atttctggct tacctcgcta ctgttctcgg
    19381 tgctttcgtc cgcaggttcg ggaacaagta acttgtgcca gggcatagtt ttgttgagca
    19441 gctccatcag aggctcagcc agcagtccca aaatccaggt tgccgtaatc accggtatag
    19501 tgagattttg tggcgtccat aactggtgat cgagatgata ccaggtgatg acacacaaaa
    19561 taccacccag ccagaacaca gcccatttaa acgcaccaag aatggctaac acaaaaacaa
    19621 agataaaatg taaaatactc gcggcaagaa gacgaagata aaaccatccc cagtcaagcc
    19681 acttaacaaa agtgctccct gttttcactg caaaacgttt cttacgctcc ctggcgattt
    19741 ctttcctgaa tttagcacgt tcttccccct gagggaattg atagatttta gccatgagtt
    19801 acctcatttc gatctcaaaa cgaagtctat gcaattatcc tctgaaaccg tatggtattc
    19861 tgatatctag gccttcactt tctttatcta ttttataaga aaaccttagc tttgatgctc
    19921 ttcttgcgac tctctcaacg attttaactt cgagatgatt aatctctgta tattgattta
    19981 ttttttcaat gtttttttgc agaaaaactt tattaaagtc cttaaaattc tgataaaggt
    20041 aaactttttc gccattatct attctgaata attcaagttc atcctttaat acatctactt
    20101 caatgtcaaa aaatgtcttt ttaccactgc tgtattgttt cctgataaac tgataaagca
    20161 tatttgaatt ttgatcagca agtcttacag acgatatcaa aacctgagta gtgtaagaat
    20221 cctttaacat cgtgatatat ggctcaatga catgtgaaaa agcaatatca atatatcctt
    20281 cactttcaac ataatcacaa aacgcagtca ggttcataag cctgactgca tcagaaggta
    20341 atttacctct cttcttcgta tgtccagaga tttgattgcc ctgagctgtg agaagttgat
    20401 ttcgaggaat gcgaataaca ctggcctgaa gttcttctgc cccctctttc aactgccggt
    20461 aagcacctgt tacatcaata tcagcgataa atgcatattc ccgagccgta atacgaaagg
    20521 ttgccccctc agataactct tcacgtgaat caatctgcgc catagccata aacaaaattc
    20581 ttctggcaga caaaggcaac gatgagaatg tgctgttaat ttcatttctg tggcgaattt
    20641 ttgttttctt tgtaacgctc agtaagttca tacattacct atggttttta agttctaatg
    20701 gtgaaatcat aaccgcaaag gtggaaatgt gtaaagcggt ttatccacct tatgtatttc
    20761 caccaaaaca cggatcacat gaaagagttt ttatcattaa tattcaatat gatagaaatg
    20821 cgcaggtatc caccttttaa cgtcatacgt tagattagag cactataaag aactaaagaa
    20881 atgaagatac aaagatacga atatctgaat aaaaacagaa aaatgcgtac ccatccacct
    20941 ttcagtgcgt acccatccac ctttcagtgc gcagccatcc acctttcatg aaaattacag
    21001 tgcgtaccca tccacctttc agtgcgtacc catccacctt tcattttgag gcgacaaaaa
    21061 acaacagcta tcttaatgaa attattgata aaaaaactgg cacagtgttt gcagaataag
    21121 ttaaagtaag ttaaagatct taaagtagat ctaccgatct acatttaaga tcttaaaaac
    21181 aagaagttta ataagcaaaa aaacacaaaa aatctgtgga taactttgct caaaacaaaa
    21241 aattcacact acctgtggat aactttgcgt aaacccggag gacagatcat tctgaaccaa
    21301 gacaaccaca cataaaaaca acatgctcac tttttaacca ctgcgcgtaa ttgcctgatg
    21361 ttatccctgt gctgttccgc ttcctcgctc actaactcgc tacgctcggt cgttcggctg
    21421 cggcgagcgg tgtctccttt ctcaaaacca gaagagttca gatcatacga tccgttgatt
    21481 gatccttttt ggatctttca ctgagaagcc ctgaatcgct ttctgccgct tcgttcgata
    21541 caaccatggt gaaaccatgc gaaatcgaaa aaatcgctca gaatgcgata cagcgcgttt
    21601 tagagggtat ttacaaaaca gtcgttgcct tgaggaaatt ttgatcaaga ttgaactcct
    21661 atccggatca tggcaacaga tcacagcaac aaggccacta aaaagcgttg agcggcgtta
    21721 aacaccgtca aaccgtagcc gactacaacg aaacgggaaa aacgctcaga acgcgttaca
    21781 gagcgtttta aggcgatgtc ggaaagagcc atatctcacc tgttctgatg tttttctcaa
    21841 catgagcact tttaaaagtg cttttaaaga tgctattatg ccaatgagac aagcggaggg
    21901 cttatgagct atcaaattct gacaaccaca gcggccagta ttactgacct gaaaaaaaat
    21961 cctatgggaa ccgtagctga aggtgaaggg gacgctgttg cgatcctgaa ccgaaacgaa
    22021 ccggcgttct attgcgttcc accaaaactt tacgcctact atcgggaact cgctgaagat
    22081 gctgagttaa acgctgttgt tgatgagcgc atgaaaaacc cggaaattgt gaaggttaac
    22141 ctggatgacc tatgaactgg cttttgaccg tagagcactg aaggaatggc agaaactcgg
    22201 ccacaccatc cgtgaacaat tcaaaaagaa actggcagaa cggctggaaa atccacgcgt
    22261 accctcagcc cggttacatg gtcatgctga tcgctataaa atcaaacttc gtgcatctgg
    22321 ctacagactt gtatatcaag tcattgatga gaaagtcgtt ttactcgtta ttgccgttgg
    22381 aagaagggaa agcagcgaag tctatcagat cgcagatttg cgctaagatt aatcatcaaa
    22441 tgattgactg tttacagtca gagcgagagt attaaaaatt tgcaatacct gcaaatgcag
    22501 gcataataaa acacaagaaa gggaaacagg ttctctttca tccagagccc aaagtgggcg
    22561 ggaggttaaa aatgcaaaac tacgctaaat ctgtagccac agagatttta cgtcaacttg
    22621 gtggtaatcg ttttattgtt atgactggtg ctaaaagttt ttcttacttt gatgaaaacg
    22681 gtgagtgt
//
