LOCUS       NZ_CP010090.1          21380 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP010090.1 Bacillus thuringiensis serovar galleriae strain 4G5
            plasmid pBMB426, complete sequence.
ACCESSION   NZ_CP010090
VERSION     NZ_CP010090.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 23:27:33
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 92813
            Orig. end    :: 114193
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21380
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11380]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11380
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21380
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21380
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="2"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             860..1492
                     /locus_tag="ctg1_52"
                     /transl_table=11
                     /translation="MIIDHISNNVVKKLEQTVRYEKKQVQVLRVSKSSSNMHAYMIFPE
                     FSEVKIFNTDLDEYIEDLSTSLKYVIDRKLSLQEIEKQNHSFIMTCAVEEDGVIDDETI
                     HFNTTYVKPPTLASKVFKLVCGLGNRLNSLKELHITVLNNNINRIEIGFYNENETYVAV
                     EKEEIANAIMGAYTKANIYYSADLRYVAEGNEIKLKSVKPKLAGDVL"
     CDS             1507..2124
                     /locus_tag="ctg1_53"
                     /transl_table=11
                     /translation="MIGVLCIFVFMIVVLIPLHTAHASVKVDFNELKGNDVSSSFKEGL
                     NNRKKATGKDDSFGSSIIQKIEGMYAPAFKVGVNIFSISFILGVIVMVMALITKNGQWM
                     KWATGSMIFSFVSMMAMRLSVYFLFSSDVFSFMNIFTDFLNLFKSTALIFTPFMLIAGI
                     RLRKIHESTKQPEYYRWSNRVITGSCFLCMLAVLAPWLFANM"
     CDS             2434..2970
                     /locus_tag="ctg1_54"
                     /transl_table=11
                     /translation="MIAICRMNRTCSRAGMPAKQTRKIETKIIFKLEIHTSYLIITQFI
                     LIGVLVLKRNREYTALRNSILIGWLLTIIVMGLSIYFSSIIYLLIGCFILSLKYGLMGT
                     IKNVEKRLPTWANFGVIEKPVNRRVTRPFQFRGGLIVSLALGFIEMVIKGLCISYYILG
                     LETHVYRLMHRNTRM"
     CDS             2987..3625
                     /locus_tag="ctg1_55"
                     /transl_table=11
                     /translation="MKVLIFELILIVLLIPINIMVKKHAPKWKGRAGEKMVKRILRKLD
                     HERYWVLHDVTVHTEYGDTTQIDHIVIAETGIFVIETKNYEGWIYGSEKAARWTQGIFR
                     KKHSFQNPFRQNYKHMKTIEWVMEQQLPCISIAAFHPKCSLKRVNVHSKDKYVLYYNDL
                     KKCIESYIDVKLTKDEVEHIYQTILQANITDKDTENKHVKYLQNKFAKQ"
     CDS             3644..3757
                     /locus_tag="ctg1_56"
                     /transl_table=11
                     /translation="MLYIIGFLVIIVVVIRLNVKYYQLKGNPKDFVMKKKD"
     CDS             3917..4660
                     /locus_tag="ctg1_57"
                     /transl_table=11
                     /translation="MKEVLDVETYLKKMKNQKINYDKVLRKMINDWEARNERPKVLLHS
                     CCAPCSTASLEFLAEHADITVFFSNSNIHPKSEYMRRSNEQKIFVEKFNDRTGHTVGFL
                     EDDYRSNVFFKMVKEEGLAEEPEGGLRCSACFDMRLDRSAEVAQEKGFDYFGSAITLSK
                     NKNSQLINELGIGVQKNYDSRYLPSDFKKSNGYQRSIEMCNEYDVFRQCYCGCSFAAEK
                     QGIDLRSVNKDAIHYLKENNLSLKK"
     CDS             complement(4818..4976)
                     /locus_tag="ctg1_58"
                     /transl_table=11
                     /translation="MQDRKKAIKSTGSVMKPDFAETDAQKVKQEIQNDVRAGQGAMTSR
                     EAGAMRD"
     CDS             complement(5324..5506)
                     /locus_tag="ctg1_59"
                     /transl_table=11
                     /translation="MIPLLIKVFLVMVCLMSIKRFPNKIYTLQFGFKLTIDSDFLMEPL
                     FKASLIALNKGFLLY"
     CDS             complement(5556..6833)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 252.8; E-value: 1.4e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_60"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.9e-42, bitscore:
                     139.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIKFLLLINLISGTFIPITTVHAENKSQYYTIMLKNYENNQK
                     LASKFQKYDMQVVYSVPEIGVIQVKATEKAMNIVHSDPNIDSYNKSLQSFNSREVATNV
                     SSPLPLNEIWENQWDMQQVTHNGDSYRLYPGTKNVTVGIIDSGIDINHPDLKDNISPGS
                     KNLVPKGGFREQESQETGELNRLIDLRGHGTFTAGQVAANGFMKGVAPGIGIKMYRVFG
                     NGAGEAIWVIKAIVEAAKDNVDVINLSLGEYLINGIVSSSDGESSEELSEIKAYRKAIK
                     YAKSKGSIIVAAAGNDALDVTNKQEMNDFFRKKNENTGVTFTGEVLDVPAELPNIVTVS
                     SVGPSKLLSLFSNYGESFIDIAAPGGDNRLFQQYGLEQWVKNKLMLKELILTTAPGGGY
                     ALSIGVSLAAPKVSGALALIIDKNNF"
     CDS             complement(7054..7701)
                     /locus_tag="ctg1_61"
                     /transl_table=11
                     /translation="MLINLVMKDFLLVKKYFLILLVFAAIAPIYLSSQLQLNDGGLVSF
                     LLTVILMEYILFGTVSKFEDQYKGAALLCATPYTRSAFVKAKYLFLFVIFICAAIIRII
                     ISVVAPSGIESLSASALGITFLTLSILFGVLLPVQFKFGYDKTKIISLLTAFLIPFVAP
                     TLIRGLQSSDIDFKSIFPFSPTVLTWMPCFISIIIGFISMIISLKVYAKKDL"
     CDS             complement(7691..8557)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 147.6; E-value:
                     7.9e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_62"
                     /transl_table=11
                     /translation="MNVVLEVNNLNKSYGNFSLKDVTFSLNTDCITGFIGTNGSGKTTT
                     IKAILGLILKDTGKINFLGKDMDKHERKSKNKIGIVLDEGYFYDELTVKEMKNVIAPSY
                     TEWDETVFQNYIKKFNLNLEQKISTLSKGMRMKFAVALALSHHADLLIMDEPTSGLDPL
                     VRSELMDILLDFMKEPGKSVFFSTHITSDLDKIADMIILIDDGKVLVNDEKDVLIDTHA
                     LVKGDNRLINKQTRPLFLNLHQTHYGFEGITNKKDDVRRLMPDVLIERPTIEEIMLSYI
                     GGNIHVN"
     CDS             complement(8554..8937)
                     /gene_functions="regulatory (smcogs) SMCOG1136:GntR family
                     transcriptional regulator (Score: 71.9; E-value: 1e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_63"
                     /transl_table=11
                     /translation="MKIVLSNVSSLPLYQQIKEQIKESIFNNELKEGEQLPSIRSLAND
                     LHVSVLTTKRVYAELETEGFIITKVGKGTYVAPTNLELLMESKRRMVEVKLTEVCQMAR
                     SIGIHADDLHSILDLILEEENEK"
     CDS             9486..9608
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_64"
                     /transl_table=11
                     /translation="METPVVQPRDWTCWSCLVCAACSVELLNLVTAATGASTAS"
     CDS_motif       9486..9515
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: METPVVQPRD"
                     /locus_tag="ctg1_64_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       9516..9608
                     /prepeptide="core"
                     /locus_tag="ctg1_64_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="28.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="WTCWSCLVCAACSVELLNLVTAATGASTAS"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="METPVVQPRD"
                     /leader_location="[9485:9515](+)"
     CDS             9714..9836
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_65"
                     /transl_table=11
                     /translation="METPVVQPRDWTCWSCLVCAACSVELLNLVTAATGASTAS"
     CDS_motif       9714..9743
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: METPVVQPRD"
                     /locus_tag="ctg1_65_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       9744..9836
                     /prepeptide="core"
                     /locus_tag="ctg1_65_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="28.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="WTCWSCLVCAACSVELLNLVTAATGASTAS"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="METPVVQPRD"
                     /leader_location="[9713:9743](+)"
     CDS             9889..9999
                     /locus_tag="ctg1_66"
                     /transl_table=11
                     /translation="MTNSYVKNKSYIFIENEYGIFVIHKLKTNLNFIGDD"
     CDS             10001..11380
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_67"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 1.3e-34,
                     bitscore: 112.7, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-08, bitscore: 29.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-07, bitscore:
                     26.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="subtilosin (E-value: 2.9e-46, bitscore:
                     152.2, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.1e-21, bitscore: 70.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.3e-09, bitscore:
                     32.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.8e-08, bitscore: 28.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGYLFWKEKLEIRKFTSNYESMLVVHKNPNESAPTLKNENTFTI
                     NKTATEIIELIDGTKTYGQVVSFLSLKYSEDPISIEKKLNAFLNNVSKVYNMNIGTQEE
                     PINVPVNLIEEQTIYPKVASIEITNRCNVRCRHCYGDFGAVKPKVMSLDQIKSLLDDLN
                     NIGVKLIELTGGDITVHPNLKEILLYALNLDFSQITLLTNGIALSEKVMDIIIKNKSKT
                     FVQIDMHSLDDNYLTWFFKVPNTLHKIKNNIMKLAENDVRLRIATIVTHLNVHEVEDIA
                     EWVHNLGIDSIGVSPVIPMGRALGCSDLYLNEEDVKTYGEALLKINKKYPKFVSLYEGA
                     RAEIRNCGAITSHIVIAPDGEIKMCTMHSLDDLKNSIGNVFEQNIKDIYDEKFKYINAF
                     FNLQAPQMDSEECKECENKRFCSTCFLRSFIKAQEIGDKCKWFKNHVPEIIKEPLMVGQ
                     N"
     CDS             11584..13293
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 174.8; E-value:
                     5.1e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_68"
                     /transl_table=11
                     /translation="MNKKINKQDEIQISYKELLFLYPYLKNTKTLLAFGLIGMVIASLI
                     IAPIPYIIGYIIDKVILLNKSYDQLLKTTLILLLIYCINYLISIGYEYLFTRVQQNVVN
                     EIRLSMISNIIDAPLSYINQKEKGYILSRIAESGNVSALFSPNLLRVFSGIFDFFFALF
                     IMFNLSVKLTGIIVIIIPIYFIISKHSSKMISKSTTNVYESSAVLNAEMYETLNGIEDI
                     KLLNGKNIQTNKIKSKLNNVIKSALKQNLHFIFFMQNLIVTNNFVTVIVLLVSGILILQ
                     NQLTIGVYTSFSIYMAKLLATTQALGSLDITLKPVCISIKRIKEFFNLDVENTLGTNIM
                     KEPINSIEFKDVCFKYNGNSDLIFDHLNVQIEKGDKLLIDGINGSGKSTFIKLLTGLYQ
                     PESGKILINNIDYNLIHKESVRDRIGIVSQNIFLFKGTILDNILYGQTNKTKEDVVKLM
                     KRYHLTSHLNRFENGLDTIIVQDGSSVSGGQAQFIAFLRAILTKRDIIILDEAASNLHI
                     DTRNLMYEILQNYNLCNILIMISHQQDGLYFLNKTLELTHGNKRIALNGSML"
     CDS             13328..13615
                     /locus_tag="ctg1_69"
                     /transl_table=11
                     /translation="MSKMKLINFDTYRNSIVLFENNGEIISVSAHFQFFEGSESYIQGF
                     IDNEEVIHFKSNNPGPNISIYRFAPKNITKLIISSENRTNGMVTLYTSEI"
     CDS             complement(13770..14621)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 205.5; E-value: 1.5e-62)"
                     /gene_kind="other"
                     /locus_tag="ctg1_70"
                     /transl_table=11
                     /translation="MVSHLCKVAGVSRSGYYNYFSVSSQEQRKQKSDRDEILKETILKA
                     LRFRNRNKGARQIKMTLAGQFQVVYNLKRIRRIMKKYEIICPVRKANPYKRMLKATKEH
                     RIVPNQLNREFKQNTPGKTLLTDITYLVYGKNQRAYLSTILDGSTNEILAYHVSEQMTL
                     ELVTTTLHKLKRNPRIRLTEGAYIHSDQGSHYTSPTYQKLVKKLNLGQSMSRRGNCWDN
                     APQESFFGHLKDEAHIKPCVSFNELKQEIKKYMTYYNHYRYQWNLKKMTPVGYRNHLLD
                     VA"
     CDS             complement(14687..15103)
                     /locus_tag="ctg1_71"
                     /transl_table=11
                     /translation="MTKKLFTEREIQILSNNLYVKSVSQKGITYTEEFKHIFIEENEKG
                     KLPRNIFEECGFDIDMIGMKRVMSSGSRWRAAYRKNGVLGLRDTRIENAGRTLERELTL
                     EEKYARLEAERNLLKAENELLKKIKLMEGRMRRK"
     CDS             complement(15453..16238)
                     /NRPS_PKS="Domain: PKS_KR (8-120). E-value: 2.9e-10. Score:
                     32.2. Matches aSDomain: nrpspksdomains_ctg1_72_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     224.1; E-value: 3.3e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_72"
                     /sec_met_domain="adh_short (E-value: 1.3e-35, bitscore:
                     117.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDLKGKVVVITGASTGLGRAMAIRFGEEQAKVVINYYSNESEA
                     NEVVQVVKQAGGEAIAVKGDVTVESDVINLVKSAVKEFGTLDVMINNAGIENSVPSHEM
                     PLSDWNKVIATNLTGAFLGSREAIKYFVEHDIKGSVINMSSVHEQIPWPLFVHYAASKG
                     GVKLMTETLALEYAPKGIRVNNIGPGAMNTPINAEKFADPEKRADVESMVPMGYIGEPK
                     EIAAVAAWLASSQASYVTGITLFADGGMSLYPSFQAGRG"
     aSDomain        complement(15879..16214)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_72_PKS_KR.1"
                     /evalue="2.90E-10"
                     /label="ctg1_72_PKS_KR.1"
                     /locus_tag="ctg1_72"
                     /protein_end="120"
                     /protein_start="8"
                     /score="32.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVVITGASTGLGRAMAIRFGEEQAKVVINYYSNESEANEVVQVVK
                     QAGGEAIAVKGDVTVESDVINLVKSAVKEFGTLDVMINNAGIENSVPSHEMPLSDWNKV
                     IATNLTGA"
     CDS_motif       complement(16140..16211)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_72_0001"
                     /evalue="5.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_72"
                     /protein_end="33"
                     /protein_start="9"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VVITGASTGLGRAMAIRFGEEQAK"
     CDS             complement(16255..17112)
                     /locus_tag="ctg1_73"
                     /transl_table=11
                     /translation="MDILLAILPALFWGSIVLFNVKLGGGPYSQILGTTLGALVFSIGV
                     YIFIKPVLTPVMIIVGIISGLFWALGQANQLKSIDLIGVSKTMPISTGMQLVSTTLFGV
                     IVFHEWSTTTSVVLGVLALLCIIIGIVLTSLQSKEEKNDEQKGNFKKGIVMLLISTLGY
                     LVYVVIIRLFGIDGWSALLPQAIGMVLGGILLTFKHQPFNKYAIHNIIPGLIWAAGNMF
                     LFISQPRVGVATSFSLSQMGIVISTLGGIFILGEKKTKRQFIAIVIGIIFIIAAGIMLG
                     IAKG"
     CDS             17315..17431
                     /locus_tag="ctg1_74"
                     /transl_table=11
                     /translation="MTNTISSFENRNNGEKLDAKLSYVIQKQRIMFIHEKKK"
     CDS             17908..18504
                     /locus_tag="ctg1_75"
                     /transl_table=11
                     /translation="MPACSNSTQTKNDSRPAQAVQNGIQQHVEGKGIVDIPGDYKGKLK
                     DLETVKGKVLYIKDGDTIDVNVKGQKQMVRLLLLDPPESVSQKIPPQKMGKEPSSFLKK
                     QLEGKSVTFVYDRGPKEDKYGRKLAYVFCVGIHINELMVKSGYGIIAYISRPNTTFLSE
                     MKEAENEAKESKVGVWSIKGFVDEKNQHYNRKDAT"
     CDS             18556..18759
                     /locus_tag="ctg1_76"
                     /transl_table=11
                     /translation="MNENKRNMLLSFINSILFIFASLLPFSNNEYVYVISKIGAAAGVI
                     NIVMMSVFLYFQSKKTGHLLNW"
     CDS             18832..19044
                     /locus_tag="ctg1_77"
                     /transl_table=11
                     /translation="MSQVPGFLKFVLAKERRYVYLVVAEKKNKKVHTHMVYRFGSLEKA
                     LETMYEMRGDFENLFPLELKERGYD"
     CDS             19265..19597
                     /locus_tag="ctg1_78"
                     /transl_table=11
                     /translation="MICAGTKEWPCMGVGIYRKDSHVSTYAFPFACIGLMLSVYQITIQ
                     AFPNSEMQICSVGVSCTKDYLNLFGFISIPMLSFVGFLAIIILLYIKSERDKRINNTAI
                     MNNMLE"
     CDS             19657..19950
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 77.5; E-value: 9.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_79"
                     /transl_table=11
                     /translation="MTTMQVSNEMYKIPEADIELLKIMAHPVRLQIVKELEHHKICNVT
                     QLTELLDVPQSTVSQHLSKMRGKILRSERRGLEMYYHIVNSKACQIVGVLGI"
     CDS             20497..20910
                     /locus_tag="ctg1_80"
                     /transl_table=11
                     /translation="MREIAKKVKMIRLQEEHSGLKADAEQYSSKRCKIERESINLEKNR
                     VKKRTQKFQTSEEKWDIKCKKAVQLFNQGEEYPTIAKKLRCNVSSLYRELKKRGTLQTP
                     KQVAVSKSLKSPITSTRAKKTNFERYKEYYMYK"
ORIGIN
        1 aagttgcagg tgggatcatt tatgattcat aacatgaaaa acgaaaaaaa taatgtttga
       61 atagtattag ttgaaccaaa agagtattct aaagagccgg atgatatatt gattaatata
      121 gataagttat tagagagtac gaatgaagaa atacgatgta aattatgtga tggtagttta
      181 tacaggggaa aaggaagaac taagtgatat gaatacttgg atcttccttt tttattgcaa
      241 ttagaaatct ggtaagaaaa attatgcgta tagaaaatag tttagggaca gaactttatt
      301 caaaattaac aagtagaaga aaaatgaaaa aatagattca aagatgaata gtttgagtac
      361 agttaattta cagaatagag agtaaaaatc atgtttacaa tggtatttat tggtctgttt
      421 tgatatgtac ttctgatagt ttgtaattct aaaaaaaaaa ggagaaatgc atgaatatat
      481 ttagaatttg aagggaattt gcttaatttt tatacattat ttgaatggaa tcatagataa
      541 ctagtgcgta tataaaatct atttcctagt tttattttct tagataaata gcgtgaaata
      601 cagtatgtct cactcatttg tataaggata aaatatcttt ttatctttat acaaatgagt
      661 gaaacagaac gattcaccat ataagaatat tcgactataa tgaaaaattg tacgtcattg
      721 taatattaag atgttttaag attaaagtga ttattaatca taaaatatga gtttcgagac
      781 ctcagcaaat attgcaatgc tttatataca tgagattgta aaaaattatt ttattaaaat
      841 tactggaggt tgatgaaata tgataataga tcatataagc aacaatgtag taaaaaaatt
      901 ggaacagacg gtgcgctatg aaaagaaaca ggtacaggta ttacgtgtaa gtaaaagtag
      961 ttctaacatg cacgcttaca tgattttccc agaattctca gaggttaaaa tttttaatac
     1021 tgatttagat gaatatatag aagatctatc aacaagtctg aaatatgtca ttgatcgcaa
     1081 gttaagtcta caagaaattg aaaaacaaaa tcattctttc attatgacat gcgcagtcga
     1141 ggaagatggt gttatagatg atgaaactat tcattttaat acgacatatg ttaagccacc
     1201 aacacttgcg agcaaagtat ttaagctagt ttgtggttta ggaaatcgtt tgaatagctt
     1261 aaaagagtta catataacag tattaaataa taatattaat cgaattgaaa ttgggtttta
     1321 caatgaaaat gaaacatatg tagcagtgga aaaagaagaa attgcaaatg cgattatggg
     1381 agcatataca aaagcgaata tttattattc agcagatctg cgttacgttg cggaaggaaa
     1441 tgaaatcaaa ttaaagagcg ttaagcctaa attagcgggt gatgtgttgt gaagcgagaa
     1501 aaaaggatga ttggtgtttt atgtatattt gtttttatga tcgtagtact gataccttta
     1561 catacagctc atgcatctgt aaaagtggat tttaatgaat taaaaggaaa tgatgtttcg
     1621 tcatctttta aagaaggatt aaataatcga aaaaaagcga caggaaaaga cgattcattt
     1681 gggtcatcaa ttatacaaaa aattgagggt atgtatgcac cagcttttaa agtaggagta
     1741 aatatttttt ctatctcatt catattaggt gttatcgtta tggttatggc gttaattaca
     1801 aagaatggtc aatggatgaa gtgggcaact gggagtatga ttttctcttt cgttagcatg
     1861 atggcgatga gattaagtgt atacttctta tttagttcgg atgtattttc gtttatgaac
     1921 atttttacgg attttttaaa tctgtttaaa tcaacagcac ttattttcac accctttatg
     1981 ttaattgcag gtattcgttt aagaaaaatt catgagagta cgaaacagcc agagtattac
     2041 cgttggtcca atcgagtcat aacgggatct tgtttcctgt gtatgttagc cgtactcgct
     2101 ccatggctat ttgcgaatat gtaaagaagt atatatagat ataaaaggta ctgaatgttc
     2161 attcagtacc ttttaactac ccatctcatt ttttctttcg tattctgcaa atatttcata
     2221 tggtataggg ggtaatatgc tacttaagta cactgttata tataattttg tttatctttg
     2281 gtttaaatag taagggtttc atgctcctca ttattgagga taatttattc gatttttaat
     2341 tgttttttgt tgcaaatata ttgctttatt tgatagagat tatgtatcgg taatctttcg
     2401 atatacagac aactacgctt taacagatag aaaatgattg ccatttgtag aatgaacaga
     2461 acttgtagta gagctggtat gcctgcaaaa cagacgagga agatagaaac taaaataata
     2521 tttaaattag aaattcatac ctcatattta ataataactc aatttatttt gataggagtg
     2581 cttgttttga aaagaaatcg agaatatacc gctttacgta attctatctt gataggttgg
     2641 ctgctcacaa ttattgttat gggcttatct atctattttt cttctattat atatttacta
     2701 attggatgtt tcattttgtc attgaaatat ggattaatgg gcactataaa gaatgtagaa
     2761 aagcgtttgc caacctgggc taattttgga gtgattgaaa agccagtgaa tcggagggtg
     2821 acaagaccgt ttcaatttcg gggcggactc attgtttcat tagcattagg attcatagag
     2881 atggtgataa aaggtttatg tatctcatat tatattttag gattagaaac ccatgtatat
     2941 cgtttaatgc atagaaacac aagaatgtga aaaggggact tatattatga aagtattaat
     3001 atttgaatta attctaattg tgcttctgat accgataaac attatggtaa aaaaacatgc
     3061 tccaaaatgg aaaggaagag ctggagaaaa gatggtaaaa cgtatattaa gaaaattaga
     3121 tcacgaaagg tattgggtgt tacatgatgt gacggttcat acagagtatg gtgatacaac
     3181 tcaaattgac catattgtta tcgcagaaac aggtatattt gttatagaaa cgaagaacta
     3241 cgagggctgg atttatggaa gtgagaaggc agcaagatgg acacaaggta tttttagaaa
     3301 gaagcactct tttcagaatc catttagaca aaactataag cacatgaaaa caattgaatg
     3361 ggtgatggaa caacagctgc cgtgtatttc tattgcagcg tttcatccaa aatgcagcct
     3421 aaaaagagta aatgttcatt ctaaagataa atatgtccta tattataacg atctaaaaaa
     3481 atgtatcgaa tcctatattg atgtgaaatt aacaaaagac gaggtcgagc atatttacca
     3541 gactattttg caagcaaata ttactgataa ggatactgaa aataaacatg tgaagtattt
     3601 acagaataag ttcgctaaac aataagaaac ggagcaagga acaatgttat atataatagg
     3661 atttttggta atcattgtag tagttattcg tcttaacgtg aagtattacc agttaaaagg
     3721 taatccaaaa gattttgtga tgaaaaagaa ggattaagga tttattttag aaatagaggt
     3781 aatagaatac atatattatt ttagccatca ccaaaggtca taagaaccgt tttacgatcg
     3841 ataaatacat acattactat attttattaa ttaatttaag tgatataata aataaaaata
     3901 aacaggaggt ttagttgtga aagaagtgtt agatgtagaa acgtatttaa agaaaatgaa
     3961 gaatcagaaa ataaattatg ataaagtatt aagaaaaatg attaatgatt gggaagcaag
     4021 gaacgaaaga ccaaaagtgt tacttcattc atgctgtgct ccttgtagta ctgcttcatt
     4081 ggaattcctt gcagaacatg cagatattac ggtttttttc tcgaattcga atattcatcc
     4141 gaaaagtgag tacatgcgac gctctaatga acaaaagatt tttgtagaaa agttcaatga
     4201 tcgtactggg cacacagtag gatttcttga ggatgactac cgttcaaatg tattttttaa
     4261 aatggtaaaa gaagaaggtt tggcagaaga gccagaaggc gggcttcgtt gttcagcttg
     4321 ttttgatatg agattggatc gttcagctga ggtagcacaa gaaaaaggtt ttgattactt
     4381 tgggagtgcc attactcttt ctaaaaataa aaatagtcaa ttaataaatg aacttggaat
     4441 cggtgtgcaa aaaaattatg attcgcgtta tttaccaagt gatttcaaaa aaagtaatgg
     4501 atatcaacgt tcaattgaaa tgtgtaatga atatgatgtt ttccgtcaat gttattgtgg
     4561 atgttcattt gcagcagaga aacaaggtat agatttaaga tcggtgaaca aagatgcaat
     4621 acattatctg aaagaaaata atcttagttt aaaaaaatag atttaatgga gagaaattcg
     4681 atgtaagatt aacctatgat ttacaaacga aacgcattat gtttctaaag gaaaaacgta
     4741 aaaagctaaa atagttcggg aataactcct tactggttaa agttctagag aagaaaaaac
     4801 caataaggag tgttttctta atctcgcatt gcccctgcct ctcgggaagt cattgctcct
     4861 tgtcctgctc ttacatcatt ttgaatttct tgtttcactt tttgtgcatc tgtttcagca
     4921 aaatctggtt tcataacaga accagtactt tttatagctt ttttacgatc ttgcatacaa
     4981 accctcctcg atttaacatt taacaatttt agtatttaca aaaatacact cggtatactc
     5041 cgagtagtat attgtttatt gaagaaaaaa ttgattacta taaagtggta gaggaacata
     5101 gggaataaca atcttccata aatatctctc tcaaaagttt agagaaatat ctgcgggaaa
     5161 aacgcctttc tctctgtgga aatataaagg aagaatagtg ttttttaatt ttggatacaa
     5221 tagtctaatt atgcaaataa ccacttgtta aggttattag taaaagtggg atccaagaat
     5281 gactaaatag ggaatctaat agatggatat ggaaaaattt aattcaatat aataaaaaac
     5341 ctttatttaa ggcaattaga cttgctttaa ataaaggttc catcaaaaaa tcactatcaa
     5401 ttgttagttt aaaaccaaat tgaagtgtat atattttatt gggaaatcgc tttatagaca
     5461 tcaagcaaac cattaccaaa aaaactttta ttagtagggg tatcattgct aactccattt
     5521 ttataaagat atctcacggc cttatctgga tttttttaaa aattattttt atcaataatt
     5581 aatgctaaag cacctgacac ttttggagcg gcaagtgaaa cccctataga gagagcatag
     5641 ccaccaccag gggcggtagt taatattagt tcttttaaca ttaacttatt ttttacccac
     5701 tgttctaaac catattgctg aaataatcta ttatctcctc caggtgcagc aatatctata
     5761 aaactttcac cataatttga aaataaggag agtaatttag atggaccaac agatgaaact
     5821 gttactatat ttggcaattc agcaggaaca tctaatactt ctccagtaaa tgttacccca
     5881 gtattttcat ttttttttct aaaaaaatca ttcatttcct gcttgttagt aacatcaaga
     5941 gcatcattac cagccgcagc aactataata cttccctttg atttagcata tttaatggct
     6001 tttctataag ctttaatttc ggataattcc tcactagatt caccgtctga agaagatact
     6061 ataccattga tgaggtattc gcctaaactt aaattgataa catcaacatt atctttcgca
     6121 gcttcaacta tggctttaat aacccaaata gcctcacctg ctccattacc aaacactcta
     6181 tacattttaa ttccaatacc aggagcaacc cctttcataa aaccattagc tgcaacctgt
     6241 ccagcagtaa aagttccatg tcctcttaga tctattaggc gatttaattc acctgtttct
     6301 tgagattctt gctctctaaa tccaccttta ggtactaaat ttttagatcc aggtgaaatg
     6361 ttatctttta aatcaggatg atttatatca atgcctgaat caatgatacc aacagttaca
     6421 tttttagttc ctggatatag tctatagcta tcaccattat gggttacttg ttgcatatcc
     6481 cattgattct cccatatttc atttaagggc aggggggaag agacattggt tgctacttct
     6541 cttgaattaa acgattgtaa tgacttatta tatgaatcta tattaggatc cgaatgaaca
     6601 atattcattg ctttttcggt agctttcact tgtataacac caatctctgg gacactatag
     6661 actacttgca tatcatattt ttgaaactta ctagctagtt tttggttatt ttcataattc
     6721 ttcaacatta tagtataata ttgtgattta ttttcagcat gaactgtagt aataggtatg
     6781 aaagttccgg aaatcaagtt aattaacaga aggaatttaa ttattttttt cataaaatca
     6841 cctcttgata tattatgtat aatccttagt ttactaaatc gttaatgaaa agagatgtta
     6901 agagaattag tgatttgaaa aatttattca ctttgatatc gataaaatgt attttaggaa
     6961 taagttcatt agagaagaga attaaataaa agggaatgag taattaaata tataaagtat
     7021 ttaattactc attcctatga tttcaaattt aaattataaa tctttttttg catatacttt
     7081 cagagatatt atcattgata taaaaccaat aataattgag atgaaacaag gcatccatgt
     7141 taggacagtt ggtgagaatg gaaaaatact tttgaaatca atatcacttg attgtagtcc
     7201 ccttataaga gtaggagcaa caaaaggtat taaaaaagca gttaaaagtg atatgatttt
     7261 ggttttgtca taaccaaatt taaactgaac aggaagtagt acaccaaata aaatacttag
     7321 agttaaaaaa gttattccaa gagcgctagc gctcaagctt tctatacccg atggtgcgac
     7381 aactgaaatg attatacgga taatagctgc acaaataaaa attacaaaaa gaaaaaggta
     7441 cttcgctttt acaaatgcgc ttcgtgtgta tggggtagca caaagtaaag ccgctccctt
     7501 gtactgatcc tcaaatttgg ataccgttcc gaacaaaata tattccatca aaataacggt
     7561 taaaagaaag ctaacaagac cgccatcgtt taattgtaat tgtgaagaaa gataaatagg
     7621 agctatagca gcaaaaacga gtaagattag aaaatatttt ttgactaaca aaaagtcttt
     7681 catcactagg ttaattaaca tggatgttcc ccccaatata tgaaagcata atctcctcaa
     7741 tagttggtct ttctattaat acatcaggca tgagtcgacg tacatcatct tttttattag
     7801 taatcccttc aaatccatag tgagtttgat gtaaatttaa aaaaagaggt cttgtttgtt
     7861 tattaattaa gcggttgtcg ccctttacca atgcatgtgt gtctattaaa acatcttttt
     7921 catcatttac taaaactttt ccatcatcaa ttaaaataat catatcagca attttatcta
     7981 aatcagatgt aatatgagtg gaaaaaaata cgcttttccc cggctctttc atgaaatcaa
     8041 ggagaatatc cattaattca ctccgtacta atggatccaa gccacttgtt ggttcatcca
     8101 ttattaatag atctgcatga tgggataggg ctaatgcaac tgcaaatttc attcgcattc
     8161 ctttggatag agtagagatt ttttgttcta gatttaagtt aaacttttta atataatttt
     8221 ggaaaactgt ttcatcccat tcagtgtagg atggagcaat aacatttttc atttccttta
     8281 ctgttaattc atcataaaaa tagccctcgt ctagcacaat accaattttg tttttagact
     8341 ttctttcatg cttatccata tcttttccta gaaaattaat tttcccagta tcttttaaaa
     8401 taagacccaa aatcgcttta attgtagtgg tctttccaga accatttgta ccgataaatc
     8461 ctgttataca gtctgtatta agtgaaaagg taacatcttt taacgaaaaa tttccgtaag
     8521 atttatttaa attatttact tctaacacaa cattcatttt tcattctcct cctctaaaat
     8581 taaatctaaa attgaatgga gatcatctgc atgaatacct atactacgag ccatttgaca
     8641 aacttcagta agtttaactt ctaccatccg gcgtttggac tccattaaca actctaaatt
     8701 tgtaggagct acataggtcc cttttccaac ctttgtaata ataaagcctt ctgtttctaa
     8761 ttctgcataa actctttttg tagtaagtac acttacatgt aagtcgttag caagtgagcg
     8821 gattgatggt aattgttcac cctcttttaa ttcattgtta aatatggatt ccttaatttg
     8881 ctcctttatc tgttgatata aaggcagact tgatacatta cttaagacta ttttcattaa
     8941 acaacctctc tatcgataag tgttatgtta tgtaatgcac accatacaca ctatacacag
     9001 ttaacattat aaattataaa aagcagttta acaagatata ctgcgattaa ataacttttc
     9061 ataaataaaa tttttagtat cagttaataa agatatttgt tattttaaat aaaccaaaaa
     9121 gaaagttttg taaatatatg tcacaaaata ttaaagaaac acacacaaaa tgtttaaaat
     9181 tttttgattg tttttagaaa acatagggag ttatacttta gtcgcaccac acaatacaga
     9241 aaagggggta ggtcaaatgg aaacaccagt agtacaacca agggactgga cttgttggag
     9301 ttgtttagta tgtgcagcat gttctgtgga attattaaat ttagttactg cggcaacagg
     9361 ggctagtact gcaagctaat atcctttcag aagttttttg gttaaaagca ctaagagaat
     9421 gagcactttt ggtcaaatta gactttctag gagaaaaata aataatcaaa aaggagatgt
     9481 tctaaatgga aacaccagta gtacaaccaa gggattggac ttgttggagt tgcttagtat
     9541 gtgcagcatg ttctgtggaa ttattaaatt tagttactgc ggcaacaggg gctagtactg
     9601 caagctaata tccttttaga agttttttgg ttaaaggtac taagagaatg agcacttttg
     9661 gtcaaatgaa ttttctagaa gaaaaataaa taaccaaaaa ggagatgttc taaatggaaa
     9721 caccagtagt acaaccaagg gattggactt gttggagttg cttagtatgt gcagcatgtt
     9781 ctgtagagtt attaaatcta gttactgcgg caaccggagc tagtactgca agttaaaatt
     9841 ttaaaatgtg agagtgttta tggtgaaatt aaattagggc ttattctaat gacaaacagt
     9901 tatgttaaga ataagtccta tatatttatc gaaaacgagt atgggatttt tgtaatacat
     9961 aaactaaaaa caaatttaaa ttttatagga gatgattaaa gtgaatggct atttattttg
    10021 gaaagaaaag ctagaaataa gaaaattcac atcaaattat gaatctatgt tggtagttca
    10081 taaaaaccca aacgaaagcg ctcctacgct taaaaacgaa aatacattta cgataaataa
    10141 aaccgccact gaaattattg agttaattga tggtactaaa acatatggac aagttgtatc
    10201 tttcttgtct ttaaaataca gtgaagatcc aataagtatt gaaaagaaat taaatgcatt
    10261 tttaaataat gtatccaaag tttacaatat gaacattggt acgcaagaag aacctataaa
    10321 tgtaccagtt aatttaattg aagaacagac tatatatcca aaagtggctt caattgaaat
    10381 cacaaacaga tgtaatgtaa gatgtcgtca ttgctatgga gattttggag cagtaaagcc
    10441 aaaagtaatg agcttagatc aaataaaatc cttattagat gacttaaata atataggagt
    10501 gaaattaatt gaacttacgg gcggtgatat aacagtacat ccaaatctaa aagagatatt
    10561 gttatatgca cttaacttgg atttttctca aataacactg ttgaccaatg gtatagctct
    10621 ttctgagaaa gttatggaca taataataaa aaataagtcg aaaacatttg tgcaaattga
    10681 tatgcatagc ttagatgata attatttgac ttggttcttt aaagttccta atacacttca
    10741 taaaattaaa aataacataa tgaaattagc cgaaaatgat gttcgtttgc ggatcgccac
    10801 aatagttaca catttgaatg tgcacgaggt agaagatata gctgaatggg tacataattt
    10861 agggattgat agtattgggg tatctccagt aataccaatg ggaagagcct taggatgtag
    10921 tgatctttat ttaaatgaag aggatgttaa aacatatggt gaagcattgt tgaaaataaa
    10981 taaaaaatat cctaaatttg tttcattata tgaaggtgcg cgcgctgaga ttaggaattg
    11041 tggtgcaata acatcacata ttgtgattgc gcctgatggt gaaattaaaa tgtgtactat
    11101 gcatagttta gatgatttga aaaacagtat aggtaatgtt tttgaacaga atattaaaga
    11161 tatttatgac gaaaaattca aatacattaa tgcatttttt aacttgcaag cacctcaaat
    11221 ggactctgag gaatgtaaag agtgtgaaaa taaacgtttt tgtagtacat gcttcttaag
    11281 aagctttata aaagcacaag aaattggcga taaatgtaaa tggtttaaaa atcatgtccc
    11341 tgaaataatt aaggagccat taatggtagg gcaaaattag tatgattgaa ggagccatta
    11401 atggtaaggg caaaattagt atgattggat gagatgaata ttgttaagtt tctgaggata
    11461 aaccaatata attccataga taatgcgtcg ggataaggtc tcaagatatc tatggaatta
    11521 tataaacctc attatattga ttcgtaaatt aatataataa atagacaaag gaggagaaag
    11581 agggtgaata agaagataaa taaacaagat gaaattcaaa tttcttataa agagttatta
    11641 tttttatatc cgtatttgaa aaatacaaaa actttgttag cttttggttt aattgggatg
    11701 gttatagctt ctttgattat cgcaccgata ccatatatta ttgggtacat tattgataaa
    11761 gttatactat taaacaaaag ctacgatcaa ttattaaaaa caactcttat actcttatta
    11821 atttattgta ttaactattt aatatcgata ggttatgagt atttatttac tcgtgtacaa
    11881 caaaatgtag ttaatgaaat tcgattatct atgataagta atattataga tgcgcctctt
    11941 tcttatatta atcagaagga gaaaggttac attcttagca gaattgctga atctggtaat
    12001 gtaagtgcat tattttctcc aaatttatta agggtttttt caggtatatt cgattttttc
    12061 tttgctttat ttataatgtt taatttaagt gttaaactta caggtatcat agtaattatt
    12121 atcccaatat attttataat atccaaacat tcttctaaaa tgatatcgaa aagtaccaca
    12181 aacgtatacg agtcatcggc agtattaaac gcagaaatgt atgaaacctt aaatggaata
    12241 gaggatataa aattattaaa cggtaaaaat atacaaacca ataagattaa gagtaaatta
    12301 aataatgtaa ttaaaagtgc gctaaaacaa aatttacatt ttattttctt tatgcaaaat
    12361 ttaatagtaa caaataactt tgttacagta atagtattac tggtatcagg tattttaatt
    12421 ttacaaaacc agcttactat aggggtgtat acttcatttt caatttatat ggctaaactc
    12481 cttgcgacta cccaagcttt aggcagctta gatataactc taaaacccgt gtgtattagt
    12541 attaagagaa ttaaggagtt cttcaattta gatgttgaaa atacactagg tacaaatata
    12601 atgaaagaac caattaattc aatagaattt aaagatgttt gttttaaata taatggaaat
    12661 agtgatttga tatttgatca tttaaacgtg caaattgaaa agggtgacaa gttattaatt
    12721 gatggtataa atggatcagg aaaatctacc tttataaaat tattaacagg tttatatcaa
    12781 cctgaaagtg gaaagatatt gataaataat attgactata acttaataca taaagaaagt
    12841 gttagagata gaataggtat agtttcacaa aatatatttt tgtttaaagg aactatatta
    12901 gataacatat tatatggaca aacaaataaa acgaaagaag atgtagttaa gttaatgaaa
    12961 aggtatcatt taacatcaca tctcaacaga tttgagaatg gattagatac tataattgta
    13021 caagatggtt ccagtgtttc aggaggtcaa gcacaattta tagccttttt aagggctatc
    13081 ctcacaaaaa gggatataat aatattagat gaagcagcat ctaatttaca tattgataca
    13141 agaaatctta tgtatgagat acttcaaaat tacaatcttt gtaatatatt aattatgatt
    13201 tcacatcagc aagatggctt gtattttctc aataaaacat tagaacttac acatggtaat
    13261 aaaagaattg ctttaaatgg tagtatgctt taatcatcat gctttcatag aagggagcat
    13321 cctaattatg tcaaaaatga aacttattaa ttttgataca tatagaaatt caatagtttt
    13381 atttgagaac aatggcgaga ttatatcagt gtcagctcat tttcaatttt ttgaaggaag
    13441 tgaaagctat attcaaggtt ttattgataa tgaagaagtt attcacttta aatctaataa
    13501 tcctggtcca aatatttcta tatatcgatt tgcgcctaag aatattacca aattaattat
    13561 atcaagtgaa aatagaacaa atggaatggt cacattgtat acttcagaaa tatagctaac
    13621 atctaaattt tttaatagtt aatacgatga agtcttggat taagatcgct tgtataacat
    13681 tatttgtttt taaatagcag ctatataatc aaaaaaaagg aatcctttat tataatctgt
    13741 accctttgta aaggacattt tgaaaaaagt taggcaacat caagaagatg atttctgtat
    13801 ccaacaggag tcatcttttt taaattccat tgatatctat aatgattata atacgtcata
    13861 tatttcttaa tctcttgttt caattcatta aaggacacgc aaggttttat atgagcttca
    13921 tctttcagat gaccaaaaaa tgattcttgt ggggcgttat cccaacagtt tcctcttctt
    13981 gacatggatt gtcctaggtt tagcttttta actagctttt gataggtagg gcttgtgtag
    14041 tgggatcctt gatctgaatg aatataagca ccttcagtca atcgaatccg cggattcctt
    14101 tttagtttat ggagagttgt cgttacgagc tctaatgtca tctgttctga aacatggtaa
    14161 gctaaaattt cattagttga gccgtctaaa attgtagata aataggccct ttgattctta
    14221 ccgtaaacta aataggtgat atctgtaaga agtgttttcc ctggggtatt ttgtttaaat
    14281 tcccgattta attgatttgg tactattcga tgttcttttg tagctttaag cattctttta
    14341 taaggattcg ctttgcgaac cggacagata atctcgtatt tcttcataat tctacggata
    14401 cgctttaaat tgtagacaac ttgaaactga cccgccaatg tcatctttat ctgacgagcc
    14461 cctttgtttc tatttctaaa tcgaagtgct tttaatatgg tttccttcaa gatttcatct
    14521 cgatcactct tttgtttccg ttgttcttga gatgaaactg aaaagtaatt atagtatccc
    14581 gaacgggata caccagctac tttacacaaa tgactgacca tattccttaa gttgtatttc
    14641 atgatgacag aacgaatcaa gatgaatttc tgactaggtg gtagtgttat ttccttctca
    14701 tcctcccttc cataagtttg atttttttta gcaattcgtt ttccgccttt agtaagtttc
    14761 gttcggcttc taaacgggca tacttttctt ctaacgtaag ctctctctca agagttcttc
    14821 cagcgttttc gatacgtgta tcccttaaac ccaatacacc attttttcta taagcagcac
    14881 gccatctact tcccgatgac ataactcgtt tcattccaat catatctata tcaaaaccac
    14941 attcttcaaa aatatttcga ggtagctttc ctttttcatt ttcctcaata aaaatatgct
    15001 taaattcctc tgtataagtg atacctttct gacttacaga ttttacgtat aggttatttg
    15061 atagaatttg aatttctctt tctgtaaata gtttttttgt cattttcaac attctccgat
    15121 cccaattttc cttttattat acaagaaata ccctatagaa tagacttttt tcaagtgtct
    15181 attctatagg gtacatttta ttataaggta ttcctttttt ttgattataa tattaaattt
    15241 attatagggt ttctttaccc atcggcattt aactaaagcg aaattgtaaa cctaaaataa
    15301 aataacttta tcctttccta taattctaca gaaagaaaag tgtatttttt gcaaaatgca
    15361 tgtgatgtca cgaataatta aaaggttatt caataaaaag cttactgccg catttaaact
    15421 tattgaaagt aactaattta gttatatatc aatcaaccac gtccagcttg gaaagatgga
    15481 tatagcgaca taccaccatc agcaaacagt gtaatacctg ttacatagct cgcttgtgaa
    15541 gaagcaagcc atgctgctac cgctgcaatt tctttcggtt ctccgatata tcccatagga
    15601 accatacttt caacatcggc acgtttttct ggatccgcaa atttttcagc attaatcggc
    15661 gtattcatag caccaggccc aatattattt acacggattc cttttggtgc atattctagt
    15721 gctaatgttt ctgtcattag cttaacgcca cctttacttg ctgcatagtg tacaaataat
    15781 ggccatggaa tttgctcgtg aacgcttgac atattaataa cactaccttt aatatcatgc
    15841 tcaacaaaat atttaattgc ttcccggctc cctaagaaag cccctgttaa attcgtagca
    15901 attaccttat tccaatcact taatggcatt tcatgtgaag gtactgaatt ttcaataccc
    15961 gcattattaa tcatgacatc cagtgtacca aattctttca cagcagattt aacgagattg
    16021 ataacatctg attcaactgt tacatctcct tttaccgcaa tcgcttctcc acctgcttgt
    16081 ttaactactt gtactacctc atttgcttct gattcgtttg aataataatt aattacaact
    16141 ttggcttgtt cttctccaaa acgaattgcc atcgctcttc ctaatcctgt ggatgcacct
    16201 gtaataacaa caactttccc ttttaaatct gtatacataa ttttttcctc ctttttatcc
    16261 tttagcaatt cctaacataa tgccagctgc aataatgaag ataattccaa tgacaatcgc
    16321 aataaattgt cgttttgttt tcttttcacc taatataaaa attccaccta aagttgagat
    16381 cacgatcccc atttgggaaa gggaaaaact tgttgccacc cctacacgcg gctgggaaat
    16441 aaataaaaac atatttcctg ctgcccaaat taaaccagga ataatattgt gaatcgcata
    16501 tttattaaat ggttgatgct taaaggttag tagaattcca cctaacacca taccaatggc
    16561 ttgtggtaat aacgctgacc atccgtctat accgaatagg cggataatta ccacatatac
    16621 taagtaacca agagttgaaa ttaataacat cacaatccct tttttgaaat ttcctttttg
    16681 ttcatcgttt ttctcctctt tgctttggag tgatgttaga acgattccga ttatgataca
    16741 aagaagtgcc agaacaccta atacaacaga tgttgttgtt gaccattcat gaaatacaat
    16801 gaccccaaat aaagtagtcg aaactaattg catccctgtt gaaataggca ttgttttaga
    16861 aaccccaatt aaatcaatac ttttcaattg attggcttgt cctaatgccc aaaataggcc
    16921 agatataatc ccgacaatta tcatcacggg cgtcaaaacg ggttttataa aaatataaac
    16981 accgatagaa aaaactagag cgccaagggt agttccaagt atttgactgt aaggaccgcc
    17041 tcctagttta acgttgaaga gtacaatact tccccaaaat aatgctggta aaatcgctaa
    17101 taaaatatcc attttttcta accttcctaa aacatattta ttaagttgaa tgcttgtacg
    17161 agatagtatc tttgtgtcga gggaattatt ttagaataag agaaattttt cgtttttcta
    17221 cccgtaatat ttgtttaccc aaaataaaag aaaaataaca tcatgttgaa aaagaaaata
    17281 actagcacga aataaaaaag ttattagaaa gaatatgacc aatacaattt caagttttga
    17341 aaataggaat aatggagaaa aacttgatgc aaaattaagc tatgttatac aaaaacaacg
    17401 cattatgttt atacatgaga aaaagaaata atatcgtaaa atctttaatt tcatatataa
    17461 aattaataag aagtatgata tgatgaaagt aacaaaatac ttctaaaact atcttgcaaa
    17521 aggacacacc tacgcataca tatgcgatag gtgtgtcctt ttttatttgt ttttaagatt
    17581 tcaagactga aaagggggat gtatattgtg taccagtaat atagcatcta ctaatgtttc
    17641 ttttgaaaaa ttgaaaagtc aggaagagaa tgaaaaaaac atagtgtcaa tatgcccgaa
    17701 ttgtaagaaa ctctcattta gagcacttta taatgattat ccaaaatgga tacagtattg
    17761 cctatattgt aattatcgag aagtaaatac aatagagagt ccgtttgttt attagatgta
    17821 gctatttacg tattttgatt aggaggaaga atttccgata tgaaaatatg aattaaggct
    17881 atttgtataa catcatttgt atttcaaatg ccagcatgta gcaattcgac gcaaacaaaa
    17941 aatgattcga gacctgccca agcagtacaa aacggaatac aacagcacgt agaagggaaa
    18001 ggtattgttg atattccagg ggattataag gggaaattaa aagacttaga gaccgttaaa
    18061 gggaaggtat tatatataaa agacggagat acaatagacg taaacgtaaa ggggcagaaa
    18121 cagatggtaa ggttactgtt attagatccc cctgagtctg tatctcaaaa aattccacca
    18181 caaaagatgg gaaaagaacc atcttccttt ttaaagaaac agctagaagg gaaaagtgta
    18241 acatttgttt atgatcgggg accaaaagaa gacaaatacg gtagaaaatt ggcttatgta
    18301 ttttgcgttg gaatacacat caacgaatta atggtcaagt cgggttatgg gattatagcc
    18361 tatatttcta gacctaatac tacatttcta tctgaaatga aagaagcaga aaatgaagca
    18421 aaagaatcaa aggttggcgt atggagcatt aaaggctttg tagatgaaaa gaaccagcat
    18481 tataaccgta aagatgcaac ttaacaccct aacccattgc aatacaaata tttgtgcaaa
    18541 atggaggttt tttgaatgaa tgaaaacaaa agaaatatgc tcttatcctt tatcaattca
    18601 attttattta ttttcgcgag tctattgcca tttagtaata atgaatatgt gtatgttatc
    18661 tccaaaattg gtgctgcagc tggtgtaata aatattgtga tgatgagcgt tttcttgtat
    18721 tttcaaagca aaaaaacggg acatttatta aattggtaat taaagctaaa tagttttcct
    18781 tactcatatt cttttaagtt tggtaaggaa agccgaaaag gagtgtgaaa ggtgagtcaa
    18841 gtacctggat ttttaaagtt tgttttagcg aaagaaagac ggtatgtata tttagttgta
    18901 gcagaaaaga aaaacaaaaa agtacataca cacatggtat atagatttgg ttcgctagaa
    18961 aaagcattag aaaccatgta cgaaatgcgt ggtgattttg aaaatctttt ccctctagaa
    19021 ttaaaagaga ggggatacga ctgagaagat atcaatgatt ggatactttc tattgaaaca
    19081 gggtattcga aacacggaaa taaactagtc atatactagc aaatgttttg tattttaaaa
    19141 aataggtgaa gcgaaaataa gatgttgatc attcaaaagt atcacattgt aattgcttgg
    19201 acgatagcta ctagtgcaat gttaattagt ttgtttttta gtgaatggat aaagctgccg
    19261 ccatgtgatt tgtgctggta ccaaagaatg gccatgtatg ggggtaggga tatatagaaa
    19321 agattcgcac gtaagcacgt atgcatttcc atttgcgtgt atcggtttaa tgttatctgt
    19381 atatcaaatt acaattcaag cgtttcctaa tagtgagatg cagatttgtt cagtaggagt
    19441 ttcttgcaca aaagattact taaatttatt cggtttcatt tcgataccta tgctatcttt
    19501 tgttggattt ttagctatca taatacttct atatattaaa tctgagagag acaaaagaat
    19561 aaacaataca gcgattatga acaatatgct cgaataaaca aaaaatacct ataaatagat
    19621 aaaaatataa agaaattaaa aaaggagaaa taaaaaatga caacaatgca agtaagtaat
    19681 gaaatgtaca aaattccaga ggcggatata gaactattaa aaatcatggc ccatccagtt
    19741 agattacaaa ttgtgaagga gctagaacac cacaaaattt gtaatgtaac acagttaaca
    19801 gagctattag atgttcctca atctaccgta tctcagcatt tatctaaaat gcgtggaaaa
    19861 attcttcgct cagaaagaag aggattagag atgtattatc atattgtgaa ttccaaggca
    19921 tgtcagattg tcggagtatt aggtatttaa ttctaaatcg aaataggatg atagaaagag
    19981 tgttgttaaa tatagctgca aaagatgatg tactgcagaa tgataaattc acaagcttaa
    20041 agtttagtcc ttctaataat ggaggagctg actgtggtga aaaattgata tagaggttac
    20101 taaaaaagag tgcagtacat gtctgcattc tttttctttg tgccatagct ataatagata
    20161 aagtattttg ttttatatga ctctgaatag gggataccgt gttttgctat gcgaaaacga
    20221 tattttcgac tttttaagca aaggggataa ttagtgtatt gatgtgtata gtatgaatta
    20281 aggtttagaa tattctgtgt caatattatc aatttactat agtttccaat tatgtaaaaa
    20341 tagaattgat tataattttc cgtaaatatt agattgaaaa ctattataag gggaatgtga
    20401 gtatttatag ctgtttataa acgatgattg gggatacaga caatagggtg atcaagtact
    20461 ggtagaattt atcaaacaaa atgaggtgac tttaacttga gagaaattgc aaagaaagta
    20521 aaaatgatac gtttacagga ggagcattcc gggcttaagg cagatgcaga acagtattct
    20581 tccaagagat gtaaaataga aagagagagt attaatttag aaaaaaatag agttaaaaaa
    20641 cgaactcaaa aatttcaaac gtcagaagaa aaatgggaca taaaatgtaa aaaagcagta
    20701 caattattta atcaaggaga ggaatatcca actattgcaa aaaaactgag gtgcaatgtg
    20761 agtagtttgt atagagaact taagaaacgg ggcacattac aaacaccaaa gcaggtagca
    20821 gtatctaaat cattaaaatc acccataaca tcaacacgag caaaaaaaac aaattttgag
    20881 agatataaag aatattatat gtacaaatag aagaattcat ggctataaat ctatacttaa
    20941 ttctttagtg ttaaaaagct cagattataa agggtacaat gaaaaaatgc atgtttagca
    21001 gcaaatcttc ttacagtatt gatagagcat cttttgggtt tttttatata tttttacatc
    21061 taacaaatat tgaaggctat tacctgttgc ttagatcata aaaatattca taaaactaaa
    21121 tccttactta tatttgttga gtagttggtt aagaagagtt tttttgcaaa tgttaaaata
    21181 agaataattt gtctaaagca aaagaatcct catgtcataa aggattcttt tagaagagtt
    21241 agagagatgt tgtcacttga ctcatattga ttttacgata aaaagaaaga atattcaatt
    21301 ttattatata tttctcaata tattcctttt atttttatat tataattaat tctttttatt
    21361 gatgtatatc tttctgtggt
//
