LOCUS       NZ_CP009778.1          15271 bp    DNA              UNK 01-JAN-1980
DEFINITION  NZ_CP009778.1 Klebsiella pneumoniae subsp. pneumoniae strain KPNIH32
            plasmid pKPN-c8b, complete sequence.
ACCESSION   NZ_CP009778
VERSION     NZ_CP009778.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 19:02:06
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(35..3040)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
     protocluster    1338..13023
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6337:8023]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6338..8023
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1338..13023
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1338..13023
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             3202..3759
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             3942..4547
                     /gene_functions="resistance (resist) AAC6-Ib (Score: 433;
                     E-value: 5.6e-133)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     62.9; E-value: 6.5e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRS
                     HIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGW
                     WEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAI
                     RCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"
     CDS             4629..4886
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDID
                     LLVTVTVRLDETTRRALINDLLETALLQIVGGDKLIIPFC"
     CDS             4898..5602
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
     CDS             6338..8023
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6"
                     /sec_met_domain="Cloacin (E-value: 2.1e-113, bitscore:
                     367.1, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
     CDS             8033..8290
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
     CDS             9165..9293
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MEKRHLRGLAVLPHMLVPCLFTESVGNFACVRSARRSLTAGA"
     CDS             10005..11969
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
     CDS             11969..12700
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
     CDS             12707..13237
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
     CDS             complement(13265..13444)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
     CDS             13513..13890
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
     CDS             complement(13952..14251)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
     CDS             complement(14241..14504)
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
     CDS             complement(14810..15229)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
ORIGIN
        1 aggggtctga cgctcagtgg aacgaaaact cacgttaagc aacgttttct gcctctgacg
       61 cctcttttaa tggtctcaga tgacctttgg tcaccagttc tgccagcgtg aaggaataat
      121 ggccgagcat attgatatgt ccgtggcaaa gcggggagag gcgtgcgata tcttcatcat
      181 tcagtgtttc accctgcgcc cggagatgat ccagagctgc ctgcatataa atagtgttcc
      241 ataacacgac ggcgttagtg accagcccca gagctcccaa ctgatcttcc tgaccgtcgg
      301 tatatcgttt tcttatctca cctttttgac cgtgacagat ggctctggca actgcatgac
      361 ggctttctcc ccgattaagc tgggtcagaa tgcgccggcg gtaatcttca tcatcaatat
      421 aattaagcag atacagcgtt ttgttgatgc gccccacttc aatgattgcc tgagtcagtc
      481 cggagggacg ttcacttttc agcaatgaac ggaccagcac tgaggcctgt actttgccca
      541 gcttcaggga gcctgcggtc cggatcattt cgtcccactg aaggactatt tttcggggat
      601 ctgattgccc tctggcaata tcattcagca cgccatagtc ggcatcatgg tccattcgcc
      661 agaaaaccga agcaccggca tcagccaggc gtggagaaaa ctggtatccc agcagccaga
      721 aaaggccaaa gacaagatcg ctggcacctg ccgtatcggt cataatttcg gttggattca
      781 gcccggtctc ctgttccaga aggccttcca gcacaaagat agagtccctc agcgtccccg
      841 gtataacgat gccatgaaag ccggaatact gatcggacac aaagttgtac caggtgatcc
      901 ctctgttatt accaaagtat ttgcggttcg gtccggcatt gattgttctg actggcgtaa
      961 caaagcgcat tccatctgca gatgccactt ctcctccacc ccatatctgt gccagtggca
     1021 gcgttgcctg aaaatcaacc agtctggcat tagcgctggt gatagtttca gcccgcagat
     1081 agttcgcttt tgtccagttc agccggtgtc gggtcagtgc aggaacattt gatctgatca
     1141 gtggttccag accgatattg caggcttcag ccatcagcac ggcgctgatg ctgacgggca
     1201 gatcatcaac tctggcactg gcttcactgg catggaaaaa ctcatcagca aatccggtat
     1261 gggcgttaat ttcgagcagc aactccgtta aatccaccgg agggagcaga tcactgatca
     1321 ttttgctcag tcgtttcaga ctgtccggct catcaagact ggcgagggga gaaattgtca
     1381 accggggctt cgggccagaa acatcgagtt cgacagcctc attttcgcca agacgtgcag
     1441 caacctgtct gtaacgacta tcaagctgat ggcccagaga ttttattgct tcctgcgggt
     1501 ctgtcgggtg ccccaaagaa cgataaacct taatccgatt tgcctgccag tcagcaccct
     1561 gtagtaatct tgcacgagga tctccccacc ggttactgcc ggtaacgtag acatccctcc
     1621 gtctcagact atcctgcagt ttactgagaa agcagagcgt gtatcccctt cgggtgatat
     1681 gtttttcctt gttaatcacc agccgtttcc atgactgact gatgatttcc gttggtgcgt
     1741 cgtcaaaaaa ctgccgccgt gagctgaact cccggctgag gtagtcacag gcattcagag
     1801 tggtaacccc ggcaggtgcg gatgaaaatt taacggtatt cagcagatgg ggcaggaaac
     1861 gacgaacgcg cccgtactgc tccaccattt cgtcatgaaa attatcgtct gagggccggg
     1921 caatttcacg gacaagcgtg atgatttcag ccagcttttg cctagggatg tagctgaaca
     1981 cctcagcacg aatcgattcg tccggtgttt cttctttcag caagtacgaa catgcgctgg
     2041 cgagcgccaa tgcagattta tccagatcct tcagcgagcg gagccgtttt ttctgcccaa
     2101 tctttctggc gtcacggatg ataacggcca gcatggcgtc cagaacgtcc agtgcatcat
     2161 ccagcgccag cgtttcccat gcaaggacaa aggcaaccag aaccgccatc cttttctgcg
     2221 gtgacatcct ggcaatattg aacaccgaag tcataccagc ataacgtgcg agatttttca
     2281 ggcgcacagc cgggagtgta ctcaggtttt cagcatgcag gccaaaatcg ttcagagttt
     2341 tccagcgttc aattgcttca ttaaacgccg gaccactgat ggtcacaggg ccttttttca
     2401 gtgattccag taaagacagg cggctgcaat cagttggccc cagcagcatc tccagctgtg
     2461 aacgctgttc ggctgacggt atcagtgcca gtttgttcca caggcgcaac gtcgcctttt
     2521 cccttacctc tgaaatcaac cgggtcagcg tggtggctcc ggggagaata atacgatgtt
     2581 gcataagcca ccctgtcgcc aggtcgaaaa gcaggccagg acgttcgttg cttatccagc
     2641 tccgggtata taaaagacgg gtaaggcgaa atgtccaggg ccaggcaaat tcacgatact
     2701 gatagtgctg acgtatcagc gctgcatgct cacggcgggt attttccctc tgaccgtatt
     2761 ctgcaagaac ggtgatatca cgaatcccga gctgtctggc ggtaaaatgc cggacgccgg
     2821 aaggaatatg attcatgtca gtaagaaaag tgcccagaaa acgcacacac ccgatttgca
     2881 gggcaatacc aagtcgattg tgatcacccc ggcttttccc gataaattct ttatccgctt
     2941 catcaagatg aaaataacgc gccagctgaa gttcatcggg ttcgccagtg aacctgccat
     3001 aactctcaac ctgctcagtg gtcaaaaaat caacgggcat atcggcctcc ctgcctgacg
     3061 gcttttttaa cacaactgca accgttcgaa atattataaa ttatcagaca tagtaaaacg
     3121 gcttcgtttg agtgtccatt aaatcgtcat tttggcataa tagacacatc gtgtctgata
     3181 ttcgatttaa ggtacatttt tatgcgaatt tttggttatg cgcgggtctc aaccagccag
     3241 cagtccctcg atattcagat cagagcgctc aaagatgcag gggtaaaagc taaccgcatc
     3301 tttaccgaca aggcatccgg cagttcaaca gatcgggaag ggctggattt gctgaggatg
     3361 aaggtggagg aaggtgatgt cattctggtg aagaagctcg accgtcttgg ccgcgacacc
     3421 gccgacatga tccaactgat aaaagagttt gatgctcagg gtgtagcggt tcggtttatt
     3481 gacgacggga tcagtaccga cggtgatatg gggcaaatgg tggtcaccat cctgtcggct
     3541 gtggcacagg ctgaacgccg gaggatccta gagcgcacga atgagggccg acaggaagca
     3601 aagctgaaag gaatcaaatt tggccgcagg cgtaccgtgg acaggaacgt cgtgctgacg
     3661 cttcatcaga agggcactgg tgcaacggaa attgctcatc agctcagtat tgcccgctcc
     3721 acggtttata aaattcttga agacgaaagg gcctcgtgat acgcctattt ttataggtta
     3781 atgtcatgat aataatggtt tcttagacgt caggtggcac ttttcgggga aaagtgcgcg
     3841 gaacccctat ttgtttattt ttctaaatac attcaaatat gtatccgctc atgagacaat
     3901 aaccctgata aatgcttcaa taatattgaa aaaggaagag tatgagtatt caacatttcc
     3961 aaacaaagtt aggcatcaca aagtacagca tcgtgaccaa cagcaacgat tccgtcacac
     4021 tgcgcctcat gactgagcat gaccttgcga tgctctatga gtggctaaat cgatctcata
     4081 tcgtcgagtg gtggggcgga gaagaagcac gcccgacact tgctgacgta caggaacagt
     4141 acttgccaag cgttttagcg caagagtccg tcactccata cattgcaatg ctgaatggag
     4201 agccgattgg gtatgcccag tcgtacgttg ctcttggaag cggggacgga tggtgggaag
     4261 aagaaaccga tccaggagta cgcggaatag accagttact ggcgaatgca tcacaactgg
     4321 gcaaaggctt gggaaccaag ctggttcgag ctctggttga gttgctgttc aatgatcccg
     4381 aggtcaccaa gatccaaacg gacccgtcgc cgagcaactt gcgagcgatc cgatgctacg
     4441 agaaagcggg gtttgagagg caaggtaccg taaccacccc agatggtcca gccgtgtaca
     4501 tggttcaaac acgccaggca ttcgagcgaa cacgcagtgt tgcctaaccc ttccatcgag
     4561 ggggacgtcc aagggctggc gcccttggcc gcccctcatg tcaaacgtta aacatcatga
     4621 gggaagcggt gatcgccgaa gtatcgactc aactatcaga ggtagttggc gtcatcgagc
     4681 gccatctcga accgacgttg ctggccgtac atttgtacgg ctccgcagtg gatggcggcc
     4741 tgaagccaca cagtgatatt gatttgctgg ttacggtgac cgtaaggctt gatgaaacaa
     4801 cgcggcgagc tttgatcaac gaccttttgg aaacggcact gttgcaaata gtcggtggtg
     4861 ataaacttat catccccttt tgctgatgga gctgcacatg aacccattca aaggccggca
     4921 ttttcagcgt gacatcattc tgtgggccgt acgctggtac tgcaaatacg gcatcagtta
     4981 ccgtgagctg caggagatgc tggctgaacg cggagtgaat gtcgatcact ccacgattta
     5041 ccgctgggtt cagcgttatg cgcctgaaat ggaaaaacgg ctgcgctggt actggcgtaa
     5101 cccttccgat ctttgcccgt ggcacatgga tgaaacctac gtgaaggtca atggccgctg
     5161 ggcgtatctg taccgggccg tcgacagccg gggccgcact gtcgattttt atctctcctc
     5221 ccgtcgtaac agcaaagctg cataccggtt tctgggtaaa atcctcaaca acgtgaagaa
     5281 gtggcagatc ccgcgattca tcaacacgga taaagcgccc gcctatggtc gcgcgcttgc
     5341 tctgctcaaa cgcgaaggcc ggtgcccgtc tgacgttgaa caccgacaga ttaagtaccg
     5401 gaacaacgtg attgaatgcg atcatggcaa actgaaacgg ataatcggcg ccacgctggg
     5461 atttaaatcc atgaagacgg cttacgccac catcaaaggt attgaggtga tgcgtgcact
     5521 acgcaaaggc caggcctcag cattttatta tggtgatccc ctgggcgaaa tgcgcctggt
     5581 aagcagagtt tttgaaatgt aaggcctttg aataagacaa aaggctgcct catcgctaac
     5641 tttgcaacag tgccctgata aatctggagc cggtgagcgt gggtctcgcg gtatcattgc
     5701 agcactgggg ccagatggta agccctcccg tatcgtagtt atctacacga cggggagtca
     5761 ggcaactatg gatgaacgaa atagacagat cgctgagata ggtgcctcac tgattaagca
     5821 ttggtaactg tcagaccaag tttactcata tatactttag attgatttaa aacttcattt
     5881 ttaatttaaa aggatctagg tgaagatcct ttttgataat ctcatgacca aaatccctta
     5941 acgtgagttt tcgttccact gagcgtcaga ccccttatat atccgcaggc tatcttatca
     6001 tcagtttctg accgtgttca gtgaccgaac aacccgaacc agacccccgt ttcttttcct
     6061 gtcccggagg gggctttctg gtatctcata taatgatttc agtaaaacat actgaggccg
     6121 gagaacggcg ccgtttgtgc tggtttttgt tgcatctgga ggggattgcg catggtgtga
     6181 gtggctgttt ttttgatcat tttcacaaaa acgcaaattt acagacttga catgaaaaac
     6241 aaggcagcgt aatttttata ctgtatataa aaccagtggt tatatgtaca gtattttatt
     6301 ttagtttatt gttttaaaag tcaaagagga aaagtatatg agtggcggag acggacgagg
     6361 tccgggtaat tcaggtctgg gacacaatgg tggtcaggcc agtgggaatg tgaacggtac
     6421 atcaggtaaa ggtggccctt catcaggtgg tggtacggat ccaaacagcg ggccgggctg
     6481 gggtacgacg catacaccta acggggatat tcataactat aacccggggg agtttggtaa
     6541 cggcgggagt aaacccggtg gtaatggcgg taacagcggc aatcatagcg ggagctctgg
     6601 tggcggacag tcttcggcca ccgcgatggc cttcggtctg cctgccttgg ccactccggg
     6661 ggctgaagga ctggctttat ccgtttccgg cgatgcgttg tcggccgctg ttgctgatgt
     6721 gctggctgcc ctgaaaggtc cgtttaagtt tggtctgtgg gggattgcga tttacggagt
     6781 gctgccttct gagatagcaa aagatgatcc gaaaatgatg tcaaaaatcg tgacgtcatt
     6841 gccggcagac acggtaacgg agacgccggt cagctccctg ccgctggacc aggcgacggt
     6901 cagcgtcact aaacgtgtgg cggatattgt gaaggacgag cggcagcata ttgcggttgt
     6961 caccggccgg ccaatgagtg ttcctgtggt ggatgcgaaa ccgacaaaac gtccgggggt
     7021 attcagtgtg tcgattccgg gtctcccgtc tctgcaggtg agcgtaccta aaggtgttcc
     7081 ggccgcgaaa gccccgccaa aaggcattat tgctgaaaaa ggtgattcac gtccggctgg
     7141 ttttacggcc ggtggtaact cccgtgaagc cgttattcgt ttcccgaaag agagcggaca
     7201 gaaaccggtc tatgtgtcgg tgacggatgt tcttactccg gcacaggtaa aacagcgtct
     7261 ggaggaagaa aagcgtcgcc agcaggcatg ggacgctgct cacccggaag aggggctgaa
     7321 aagagagtat gataaagcga aagctgagct ggatgctgaa gataaaaata ttgcgacctt
     7381 aaacagtcgc attgcatcga cagagaaggc gatccccggt gcaagggctg ctgttcagga
     7441 agccgataaa aaggtaaaag aggcagaggc aaataaagat gattttgtga cttataaccc
     7501 gcctcatgaa tatggctccg ggtggcagga tcaggttcgc tatcttgata aggatattca
     7561 gaatcagaat gagaaattaa aagctgccca gacatcttta aacgaaatga atgaatcctt
     7621 atccagggat aaggctgcgc tttccggggc gatggagagc cggaaacaaa aggagaaaaa
     7681 agcgaaggat gcagaaaata aattaaatga ggaaaagaaa aaacctcgta agggaactaa
     7741 agattacggc catgattatt ttcctgatcc caagactgaa gatattaagg ggttgggaga
     7801 gttgaaagag ggtaaaccta aaacccctaa acaaggtggt ggtggtaagc gggcccgatg
     7861 gtatggtgat aaaaagcgta aaatttatga atgggattcc cagcacggtg agcttgaagg
     7921 gtaccgcgcc agtgatggcg aacacctcgg ggcattcgat ccaaaaacgg gtaagcaggt
     7981 taaagggccg gatccaaaac gaaacattaa aaaatatctt taagaggtaa atatggggct
     8041 taaattacat attcattggt ttgataagaa aaccgaagag tttaaaggtg gtgaatactc
     8101 aaaagacttc ggtgatgatg gttctgtcat tgaaagtctg gggatgcctt taaaggataa
     8161 tattaataat ggttggtttg atgttgaaaa atcatgggtt tcgatattac agccacactt
     8221 taaaaatgta atcgatatta gtaaatttga ttactttgta tcctttgttt accgggatgg
     8281 taactggtaa gcaaaagtta tcaaggatga tttgaaatac agacttccgg tgttcaggga
     8341 tgaataccgg ggtttttaaa tacagggaag gtatatgaaa aaggtaaagg ttgtttttct
     8401 ttttatattg attttttcag gctttcttct ggtcgcatgt caggcaaact atatccggga
     8461 tgttcagggt ggaacggtgg caccatcgtc ctcctctgaa ctgacgggga tcgcggttca
     8521 gtagaaaaga tcaaaggatc ttcttgagat cctttttttc tgcgcgtaat cttttgccct
     8581 gtaaacgaaa aaaccacctg gggaggtggt ttgatcgaag gttaagtcag ttggggaact
     8641 gcttaaccgt ggtaactggc tttcgcagag cacagcaacc aaatctgtcc ttccagtgta
     8701 gccggacttt ggcgcacact tcaagagcaa ccgcgtgttt agctaaacaa atcctctgcg
     8761 aactcccagt taccaatggc tgctgccagt ggcgttttgc gtgcttttcc gggttggact
     8821 caagtgaaca gttaccggat aaggcgcagc agtcgggctg aacggggggt tcttgcttac
     8881 agcccagctt ggagcgaacg acctacaccg agccgagata ccagagtgtg agctatgaga
     8941 aagcgccaca cttcccgcaa gggagaaagg cggaacaggt atccgggaaa cggcagggtt
     9001 ggaacaggag agcgcaagag ggagcgattc atcggaaacg gtgatgatct ttaagtcctg
     9061 tcgggtttcg ccactcctga ctgattcatg gttgagccac cggctcccac agatgcaccg
     9121 aaaaagcgtc tgtttatgtg aactcagtca ggagggcgga gcctatggaa aaacgccacc
     9181 tgcgtggcct tgccgttttg cctcacatgt tagtcccctg cttattcacg gaatctgtgg
     9241 gtaactttgc atgtgtccgc agcgcccgcc gcagtctcac ggccggagcg tagcgaccga
     9301 gtgagcgagg aggcgcaatt tccccggcac ctacaagacg gacaccggac gcgctgatgt
     9361 ggcatattgt cccctgatta agtctttata ttccctgata ataaattacc aggataggtg
     9421 aatcatatcg gtttttcgct gaacatttta cgttaaccta tctctgttgc ttttttctcc
     9481 ttacggagaa atacaggtca tccccgcgag ggcgtggctg acctcagggg gatatcccct
     9541 gcttacgctg gctggacgcc accgacgcac ggtctctccc cctctttctg gctccgtccg
     9601 gctggacgcc ggccacgcca gaaattcacc cggcccccgt caggctcacg cctgaccacc
     9661 cacaaaaatc cacggtgctg gacgcacctg gcgaagcagc aaagctgctc ctgattttgc
     9721 gggtggtcag ccgctcgcta tggcgaactc tgacgggggc cggaacaccg gaaaagaccg
     9781 cactggggtg ccgccttttc ctctcacacg ctggggcgtg ctcgttgttc ctccggggct
     9841 gcgccttttc cgcatggggc ggaaagaggc tggcctccgt ggtgaaagct gaacgcaatc
     9901 accacggacg tgaccgccgc cgccatgcct tggggcatgt ccgcggcttg tgcagcgggg
     9961 gctgcacatc acgccggcaa accatcgtct gaaggagaga gaacatgttt aatacggatt
    10021 cgcttgcctg gaagtggcac attccggagc tggcccggca gatttatccg tgggtcagct
    10081 ggctgtacca ggagtattac ggtctggccg gggctttcct agttatcggc ctgtttttcg
    10141 gtctggctga actttgggcc ggacggatgc gttttgtggg gctgagtcat aaggagcgac
    10201 gggagtatgc cgatcgctat aagcgcgata ataaacggcc agcgccattt tcggtgctgg
    10261 cctcgctgga ttcgcccggg cggatggtca gggcacgtcg acatgtctgg aactacgcgt
    10321 actggctgac cggcgcggcc ggtctggccc ttctgggggg gctggttgtc gccgtgttta
    10381 tcgagagctg gggagaaacc gtcctgcgtc cggacctcta cgcaaacgca gattattacc
    10441 tgctgcagcc ggctaacctg ttcgggattg cctggtgcgc gggcgggctg gctgtcggga
    10501 ttgtgttggc gcggctgctg gcgttcctgc tgcttgacgg tcattttgcg gctgctgacg
    10561 aggcggtgaa cgcgaaactg aatcaggaga gccggcgcag cagccagcgg acaggagaga
    10621 tgaccgacgt gcgccacctg catttcgggg agccggtacc ggttaatgcg ctggccgatt
    10681 tttcctcgga gcaggcccgg caggagcagg cggtgtttct gggtaaggat gagcagggca
    10741 agccggtgct ggttccgcgt gatacctggc gcaagaccaa cattcagatc ctcggcctgc
    10801 ccgggagcgg caagagcgtg atggccacca acgcgctcat tcgctgcgta cgcgatttcg
    10861 gggacgcggt ggtgtacttc gaccccaaag gggacgcatg ggcgccgcac gtcttccggg
    10921 cgcactgtcc ggacttcacc ctgctggatc tgcggccggg gaaaccggcg cagctgaatc
    10981 tgttccgcga tctcgaccag tacgcgctga aaaacctgct gattgccggg cttaacctgg
    11041 gcgagaccgg cgacgtggcg gaccactacc gcatcagcga gcagaaagcg gcgaagctga
    11101 ttgcggagca gtttccgcag ggggcaaaca ttcagcaggt gctggcggcg gcgtacgcgc
    11161 tgccggaggc cctgaaaaag gacgtgaagg ggttgatcac taggctggaa aacgtcgctg
    11221 acctgagcgt cctgcagacg gacagtggca tcgatgtggc ggggattatc aacggcggcg
    11281 gctgcctgta cgttatcggc tcgatggacg acgaggcggt gatccgtgtg caaaaaatgc
    11341 tgtttgcccg ctgcgcgcaa atcatcattg cgcgggacga gttccgggag tggccacacg
    11401 tcagcgtgat gctcgatgaa attaaatatc tgctgtcgaa gtatgtactg aacgcactgg
    11461 ggacgctgcg cagccgggac tgcaatctgt tgctcgcgca ccagtcgctg ggcgatttcg
    11521 ggcagtgcgg gcaggatctg cccgctgaat ttgtgaaaac cacggtactg gataacacgc
    11581 cgatccgctg gttttaccgg gcggccagcc tggagtccgc gcagtgggcg gcggggcaga
    11641 ccggggaaat cagggtggac gtggagcgcc gccgtgccag ccgggaggcg gggaacgtgg
    11701 agcatatcag cggggacagc ttcatccaga aggaggcgcg gccgctgttt gacgtgaaca
    11761 ccctgcaaca cctgccggac gggttcgcgg tcatgaccgg gctgggtgtg gcccggatgg
    11821 cgttcagcag tccgctgcgg gttgagcgcc gggaaatccc gttgcagcgt ttcccggtgc
    11881 tggcgaaaac cgatcccctg gcggagttcc ggcccccggc cgacggcggc gggccgaaag
    11941 cggatgatga ttttgcgggg atttactgat ggcgctggag ctgtacaacg tcagccacgc
    12001 gaaacgacag gcgcggaacg cggagaaaac ccggctgacc ctgcgctggt tgcgggaaga
    12061 gctgtgttcc acggcggagc tggttgcgcg gcggctgggg attgcggcgg tgcagccggt
    12121 ctaccgcttc ctcgacagcc tggtggcgaa agggctgctg gtccggacca aatatccggt
    12181 ggacggccgt caggtcagcg tgtgggggct gacgccgcat ggcgtggcgt tctcgttcga
    12241 cgaggacgaa ccgctggcgg atgttattcc gtttcagccg tcaagggtgt cggcagcaca
    12301 tctgccgcac cggctggccg tgcaatccct gcgccttgat atggaagcca gaggggccac
    12361 cggctggcgc attctgcacc gtctgagtct taaaggcatg aaagtgccgg acgccctggc
    12421 ggagctggac ggtaaaacgg tggcgtttga ggtggagcgc accgtcaaga gccgtcgccg
    12481 gtatcaggaa gtggtgtccg ggtatctgtt caaccgcaaa gctaacggca tcgatgaaat
    12541 ctggtacatc tgcccggacc gggcgacgca ggtcagggtg cagcgggcaa tcctgtcggt
    12601 ggatgaaatc gtgaacccac agaccggcga ggcccgcaaa acggcagagc tggatcgtga
    12661 acggttgttt gcgtgcttta aatttatgac aacggagtga gggattatgg cgctgtacat
    12721 ggtatttatt gaagacgcgg aggaccggaa cggcgagcgc tgcatcatgc cgaccagcga
    12781 gcatctggaa gatatggtgg tgctcgcctg gcagaccggg gcgtatgttt tctgttttgt
    12841 cgaccgggcc cagcatctgg cgatgatgaa atccatcggg atgtatgacg agcggctcaa
    12901 cagcgacgaa aaagccacgt actttttcac tggtaaaaat ccgcaatggg aacggaacaa
    12961 acccacagga atgaagctgt gtgattacct ctatcgcaag gtggagcggt tcgccatcga
    13021 gaacggtgtg caggtggttg atgccgggaa gtgctcaccg gagcagatta acgcgatgat
    13081 tgacgtggtg agtgagcggc acggggaaag cgcggtgaac gagaagctga aagcggagct
    13141 gatgcgggaa tataacagcc gctattttaa cgtgccggta cctgaactgc cggaggacaa
    13201 acctgcccgc cggtggtggc cgttcggcaa aaaataaatg ccagcaccgg ccatgccggt
    13261 gctgttattc ctccccgagc ttatcccgca tcacctgcca gagtgtttcc gcatcctcgt
    13321 gtagccgctc gcacatgtcg gccggggtat ccatatccag ctcattcagt ttatcgagca
    13381 atagcagcga ctgctcctta ataaatttag ccatattgag ggctgttttt tcctgttttg
    13441 tcatgattct ttccttccgg gcatggtgtg cgcctgtcag gtatactgtc tcaaaaatag
    13501 cggggtgaga caatggcgtg ggtgacggtg agacaggcga cggaactgac gggtaaagcc
    13561 cgaagttccc tgtatcggga tatggcgaaa ggccgcgtat cataccgtac ggaagctgat
    13621 ggcggccggg tggtggatac cagcgagctt atccgggtgt acggtgagtt aagacaggat
    13681 gagactcacg agcgggacga gttgagactg tcgggtgaga ctgaaaaaat ggcctccgac
    13741 gcgttgatcg cggagataaa agcactcagg gaggaggtgg ccgggctacg gcaggaaatg
    13801 cagtccatga gactgctgga acacaaaccg gagacagcag agaccccggc cggaacaccg
    13861 cgccggtggt ggccgtgggg aaaacgctga cgcgctgtgc ttgtccaacc ggcgacggcc
    13921 acgcaatgaa ttgcgtcccc gtcaccggtt attagagaac aatatgggga ttctggcgct
    13981 ggccgaccac ggccagaacc cggacttttc tggtctggtc atcaacatca tagaggacat
    14041 gctgtcccat cagactgatc cggcgaacgt cctcgccata gcgtgagtcc acttcataga
    14101 gtcgcgggaa gtcggccagt ttgtccgccg cagcgagaac ccggtcggta acgttctgcg
    14161 catcccacag ggatgaattt tccgcgatat agtcaaacag cgtcgttaca tcctcgatgg
    14221 ctccctgctt ccattccacg tcatacggca tcgcgcagtt cctgataacg gccatgcagg
    14281 cgctggcgga gttgttccgt ggtcataccc ggacgcgtgt cagcacgggc ggcggtcact
    14341 ttggcgcgaa cctgatcttc atactctgcc tgggccagtt cttcgttagc cagtcgctgc
    14401 aacagcgcag ctttgtccgg gccaccttcc ggcagtatgc ggggcaggct ttcagccagt
    14461 tcccgaagaa agttggcgtt ttcgtagtgt gtagtgttgc tcattgcgga gcctcccggg
    14521 ttaatgcggc aatatgaagg aagtttagca gggggcggtc tgaaagaata tggtcgtgtc
    14581 agtcaggctg atgaagcaga aagtcggtaa aaaagggctt acggcatcca ttttacgtca
    14641 aaacatatgc catgcagttg cgtgcatagg catgcattag gataaaattt atcgggcgcg
    14701 tttccggcag ttttccgggg gggttgttgc ctgttttatc ccgtagccgc cggaaacgcc
    14761 ctgagcccgt ctgagcggtg cgcgtaatga cgcgttatgg taaatccact tactgtctgc
    14821 cttcatagcc atcgagataa acagctgaaa tggtgtcagc cagtagcctt gattttttcg
    14881 gtgtgaggtc tttgctgcgg taatcggtac ccgcaaattg tgttgtgcct tggagtgagt
    14941 ttaaaaattc ctgactgtga aactgctgaa tgcgttgctg cacatcactc cgtgattttc
    15001 cggtcgcttt atcctttgcg cccatatccc agaactgccg gaaaaaaggc accatcattc
    15061 gtgttgtgtc agctttctgg gtggaaaaat tgggatcaaa accgtcatct gaagcatata
    15121 cgtaatgccg ggtatgctgt tccacgctgc cctttggagc acaggcagtg agagttgctg
    15181 tcgctgttat catggcgata agacacagtt tgctgccgga acgtctcatg agcgtctcct
    15241 tacctttaat tcttttttct cattgagtta t
//
