LOCUS       NZ_CP004860.1          21380 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP004860.1 Bacillus thuringiensis serovar kurstaki str. YBT-1520
            plasmid pBMB422, complete sequence.
ACCESSION   NZ_CP004860
VERSION     NZ_CP004860.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:00:48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 102901
            Orig. end    :: 124281
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21380
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11380]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11380
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21380
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21380
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="2"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             1026..1658
                     /locus_tag="ctg1_69"
                     /transl_table=11
                     /translation="MIIDHISNNVVKKLEQTVRYEKKQVQVLRVSKSSSNMHAYMIFPE
                     FSEVKISNTELDEYIENLSTSLKYVIDRKLSLQEIEKQNHSFIMTCAVEEDGVIDDETI
                     HFNTTYVKPPTLASKVFKLVCGLGNRLNSLKELHITVLNNNINRIEIEFYNENETYVAV
                     EKEEIANAIMGAYTKANIYYSADLRYVAEGNEIKLKSIKPKLAGDVL"
     CDS             1655..2290
                     /locus_tag="ctg1_70"
                     /transl_table=11
                     /translation="MKREKGMIGVLCTYVFMILVLIPLHTAHASVKMDFNELKGNDVSS
                     SFNEGLNNRTKTTEKDDSFGSSIIQKVEGMYAPAFKVGVNIFSISFILGVIVMVMGLIT
                     KNGQWMKWATGSMIFSFVSMMAMRLSVYFLFSSDVFSFMNIFTDFLDLFKATALIFTPF
                     MLIAGIRLRRIHESTKQPEYYRWSNRVITGSCLLCMLAVLAPWLFANM"
     CDS             2587..2970
                     /locus_tag="ctg1_71"
                     /transl_table=11
                     /translation="MKRNPEYTALRNSILIGWLLTIIVMGLSIYFSSIIYLLIGCFILS
                     LKYGLMGTIKNVEKRLPTWANFGVIEKTVNRRVTRPFQFRGGLIVSLALGFIEMVIKGL
                     CISYYILGLETHVYRLMRRNTRM"
     CDS             2987..3625
                     /locus_tag="ctg1_72"
                     /transl_table=11
                     /translation="MKVLIFELILIVLLIPINIMVKKHAPKWKGRAGEKMVKRIVRKLD
                     HERYWVLHDVAVHTEYGDTTQIDHIVIAETGIFVIETKNYEGWIYGSEKAARWTQGIFR
                     KKHSFQNPFRQNYKHMKTIEWVMEQQLPCISIAAFHPKCSLKRVNVHSKDKHVLYYNDL
                     KKCIESYIDVKLTKDEVEHIYQTILQANITDKDTENKHVKYLQNKFAKQ"
     CDS             3644..3757
                     /locus_tag="ctg1_73"
                     /transl_table=11
                     /translation="MLYIIGFLVIIVVVIRLNVKYYQLKGNPKDFVMKKKD"
     CDS             3917..4660
                     /locus_tag="ctg1_74"
                     /transl_table=11
                     /translation="MKEVLDVETYLKKMKNQKINYDKVLRKMINDWEARNERPKVLLHS
                     CCAPCSTASLEFLAEHADITVFFSNSNIHPKSEYMRRSNEQKIFVEKFNDRTGHTVGFL
                     EDDYRSNVFFKMVKEEGLAEEPEGGLRCSACFDMRLDRSAEVAQEKGFDYFGSAITLSK
                     NKNSQLINELGIGVQKNYDSRYLPSDFKKSNGYQRSIEMCNEYDVFRQCYCGCSFAAEK
                     QGIDLRSVNKDAIHYLKENNLSLKK"
     CDS             complement(4818..4976)
                     /locus_tag="ctg1_75"
                     /transl_table=11
                     /translation="MQDRKKSIKSPGSVMKPDFAETDAQKVKQEIQNDVRAGQGAMTSR
                     EAGAMRD"
     CDS             complement(5436..6833)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 268.8; E-value: 1.9e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_76"
                     /sec_met_domain="Peptidase_S8 (E-value: 5.7e-43, bitscore:
                     141.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIKFLLLINLISGTFIPITTVHAENKSQYYTIMLKNYENNQK
                     LASKFQKYDMQVVYSVPEIGVIQVKATEKAMNIVHSDPNIDSYNKSLQSFNSREVATNV
                     SSPLPLNEIWENQWDMQQVTHNGDSYRLYPGTKNVTVGIIDSGIDINHPDLKDNISPGS
                     KNLVPKGGFREQESQETGELNRLIDLRGHGTFTAGQVAANGFMKGVAPGIGIKMYRVFG
                     NGAGEAIWVIKAIVEAAKDNVDVINLSLGEYLINGIVSSSDGESSEELSEIKAYRKAIK
                     YAKSKGSIIVAAAGNDALDVTNKQEMNDFFRKKNENTGITFTGEVLDVPAELPNIVTVS
                     SVGPSKLLSLFSNYGESFIDIAAPGGDNRLFQQYGLEQWVKNKLMLKELILTTAPGGGY
                     ALSIGVSLAAPKVSGALALIIDKNNFKKNPDKAVRYLYKNGVSNDTPTNKSFFGNGLLD
                     VYKAISQ"
     CDS             complement(7054..7701)
                     /locus_tag="ctg1_77"
                     /transl_table=11
                     /translation="MLINLVMKDFLLVKKYFLILLVFAAIAPIYLSSQLQLNDGGLVSF
                     LLTVILMEYILFGTVSKFEDQYKGAALLCATPYTRSAFVKAKYLFLFVIFICAAIIRII
                     ISVVAPSGIESLSASALGITFLTLSILFGVLLPVQFKFGYDKTKIISLLTAFLIPFVAP
                     TLIRGLQSSDIDFKSIFPFSPTVLTWMPCFISIIIGFISMIISLKVYAKKDL"
     CDS             complement(7691..8557)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 148.9; E-value:
                     3.1e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_78"
                     /transl_table=11
                     /translation="MNVVLEVNNLNKSYGNFSLKDVTFSLNTDCITGFIGTNGSGKTTT
                     IKAILGLILKDSGKINFLGKDMDKHERKSKNKIGIVLDEGYFYDELTVKEMKNVIAPSY
                     TEWDETVFQNYIKKFNLNLEQKISTLSKGMRMKFAVALALSHHADLLIMDEPTSGLDPL
                     VRSELMDILLDFMKEPGKSVFFSTHITSDLDKIADMIILIDDGKVLVNDEKDVLIDTHA
                     LVKGDNRLINKQTRPLFLNLHQTHYGFEGITNKKDDVRRLMPDVLIERPTIEEIMLSYI
                     GGNIHVN"
     CDS             complement(8554..8937)
                     /gene_functions="regulatory (smcogs) SMCOG1136:GntR family
                     transcriptional regulator (Score: 71.9; E-value: 1e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_79"
                     /transl_table=11
                     /translation="MKIVLSNVSSLPLYQQIKEQIKESIFNNELKEGEQLPSIRSLAND
                     LHVSVLTTKRVYAELETEGFIITKVGKGTYVAPTNLELLMESKRRMVEVKLTEVCQMAR
                     SIGIHADDLHSILDLILEEENEK"
     CDS             complement(8937..9062)
                     /gene="allorf_111838_111963"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_111838_111963"
                     /protein_id="allorf_111838_111963"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKSYLIAVYLVKLLFIIYNVNCVWCVWCALHNITLIDREVV"
     CDS_motif       complement(9033..9062)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKSYLIAVYL"
                     /locus_tag="allorf_111838_111963_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(8937..9032)
                     /prepeptide="core"
                     /locus_tag="allorf_111838_111963_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="28.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="VKLLFIIYNVNCVWCVWCALHNITLIDREVV"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKSYLIAVYL"
                     /leader_location="[9032:9062](-)"
     CDS             9486..9608
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_80"
                     /transl_table=11
                     /translation="METPVVQPRDWTCWSCLVCAACSVELLNLVTAATGASTAS"
     CDS_motif       9486..9515
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: METPVVQPRD"
                     /locus_tag="ctg1_80_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       9516..9608
                     /prepeptide="core"
                     /locus_tag="ctg1_80_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="28.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="WTCWSCLVCAACSVELLNLVTAATGASTAS"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="METPVVQPRD"
                     /leader_location="[9485:9515](+)"
     CDS             9714..9836
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_81"
                     /transl_table=11
                     /translation="METPVVQPRDWTCWSCLVCAACSVELLNLVTAATGASTAS"
     CDS_motif       9714..9743
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: METPVVQPRD"
                     /locus_tag="ctg1_81_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       9744..9836
                     /prepeptide="core"
                     /locus_tag="ctg1_81_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="28.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="WTCWSCLVCAACSVELLNLVTAATGASTAS"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="METPVVQPRD"
                     /leader_location="[9713:9743](+)"
     CDS             9889..9999
                     /locus_tag="ctg1_82"
                     /transl_table=11
                     /translation="MTNSYVKNKSYIFIENEYGIFVIHKLKTNLNFIGDD"
     CDS             10001..11380
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_83"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 1.3e-34,
                     bitscore: 112.7, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-08, bitscore: 29.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-07, bitscore:
                     26.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="subtilosin (E-value: 2.9e-46, bitscore:
                     152.2, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4e-21, bitscore: 70.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.3e-09, bitscore:
                     32.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.7e-08, bitscore: 28.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGYLFWKEKLEIRKFTSNYESMLVVHKNPNESAPTLKNENTFTI
                     NKTATEIIELIDGTKTYGQVVSFLSLKYSEDPISIEKKLNAFLNNVSKVYNMNIGTQEE
                     PINVPVNLIEEQTIYPKVASIEITNRCNVRCRHCYGDFGAVKPKVMSLDQIKSLLDDLN
                     NIGVKLIELTGGDITVHPNLKEILLYALNLDFSQITLLTNGIALSEKVMDIIIKNKSKT
                     FVQIDMHSLDDNYLTWFFKVPNTLHKIKNNIMKLAENDVRLRIATIVTHLNVHEVEDIA
                     EWVHNLGIDSIGVSPVIPMGRALGCSDLYLNEEDVKTYGEALLKINKKYPKFVSLYEGA
                     RAEIRNCGAITSHIVIAPDGEIKMCTMHSLDDLKNSIGNVFEQNIKDIYDEKFKYINAF
                     FNLQAPQMDSEECKECENKRFCSTCFLRSFIKAQEIGDKCKWFKNHVPEIIKEPLMVGQ
                     N"
     CDS             11545..13254
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 174.8; E-value:
                     4.8e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_84"
                     /transl_table=11
                     /translation="MNKKINKQDEIQISYKELLFLYPYLKNTKTLLALGLIGMVIASLI
                     IAPIPYIIGYIIDKVILLNKSYDQLLKTTLILLLIYCINYLISIGYEYLFTRVQQNVVN
                     EIRLSMISNIIDAPLSYINQKEKGYILSRIAESGNVSALFSPNLLRVFSGIFDFFFALF
                     IMFNLSVKLTGIIVIIIPIYFIISKHSSKMISKSTTNVYESSAVLNAEMYETLNGIEDI
                     KLLNGKNIQTNKIKSKLNNVIKSALKQSLHFIFFMQNLIVTNNFVTVIVLLVSGILILQ
                     NQLTIGVYTSFSIYMAKLLATTQALGSLDITLKPVCISIKRIKEFFNLDVENTLGTNIM
                     KEPINSIEFKDVCFKYNGNSDLIFDHLNVQIEKGDKLLIDGINGSGKSTFIKLLTGLYQ
                     PESGKILINNIDYNLIHKESVRDRIGIVSQNIFLFKGTILDNILYGQTNKTKEDVVKLM
                     KRYHLTSHLNRFENGLDTIIVQDGSSVSGGQAQFIAFLRAILTKRDIIILDEAASNLHI
                     DTRNLMYEILQNYNLCNILIMISHQQDGLYFLNKTLELTHGNKRIALNGSML"
     CDS             13289..13576
                     /locus_tag="ctg1_85"
                     /transl_table=11
                     /translation="MSKMKLINFDTYRNSIVLFENNGEIISVSAHFQFFEGSESYIQGF
                     IDNEEVIHFKSNNPGPNISIYRFAPKNITKLIISSENRTHGMVTLYTSEI"
     CDS             complement(13942..14727)
                     /NRPS_PKS="Domain: PKS_KR (8-120). E-value: 2e-10. Score:
                     32.7. Matches aSDomain: nrpspksdomains_ctg1_86_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     225; E-value: 1.7e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_86"
                     /sec_met_domain="adh_short (E-value: 1.7e-35, bitscore:
                     117.2, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDLKGKVVVITGASTGLGRAMAIRFGEEQAKVVINYYSNESEA
                     NEVVQVVKQAGGEAIAVKGDVTVESDVINLVKSAVEEFGTLDVMINNAGIENSVPSHEM
                     PLSDWNKVIATNLTGAFLGSREAIKYFVEHDIKGSVINMSSVHEQIPWPLFVHYAASKG
                     GVKLMTETLALEYAPKGIRVNNIGPGAMNTPINAEKFADPEKRADVESMVPMGYIGEPK
                     EIAAVAAWLASSQASYVTGITLFADGGMSLYPSFQAGRG"
     aSDomain        complement(14368..14703)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_86_PKS_KR.1"
                     /evalue="2.00E-10"
                     /label="ctg1_86_PKS_KR.1"
                     /locus_tag="ctg1_86"
                     /protein_end="120"
                     /protein_start="8"
                     /score="32.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVVITGASTGLGRAMAIRFGEEQAKVVINYYSNESEANEVVQVVK
                     QAGGEAIAVKGDVTVESDVINLVKSAVEEFGTLDVMINNAGIENSVPSHEMPLSDWNKV
                     IATNLTGA"
     CDS_motif       complement(14629..14700)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_86_0001"
                     /evalue="5.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_86"
                     /protein_end="33"
                     /protein_start="9"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VVITGASTGLGRAMAIRFGEEQAK"
     CDS             complement(14744..15601)
                     /locus_tag="ctg1_87"
                     /transl_table=11
                     /translation="MDILLAILPALFWGSIVLFNVKLGGGPYSQILGTTLGALVFSIGV
                     YIFIKPVLTPVVIIIGIISGLFWALGQANQLKSIDLIGVSKTMPISTGMQLVSTTLFGV
                     IVFHEWSTTTSVVLGVLALLCIIIGIVLTSLQSKEEKNDEQKGNFKKGIVMLLISTLGY
                     LVYVVIIRLFGIDGWSALLPQAIGMVLGGILLTFKHQPFNKYAIHNIIPGLIWAAGNMF
                     LFISQPRVGVATSFSLSQMGIVISTLGGIFILGEKKTKRQFIAIVIGIIFIIAAGIMLG
                     IAKG"
     CDS             15797..15913
                     /locus_tag="ctg1_88"
                     /transl_table=11
                     /translation="MTNTISSFENRNNGEKLDAKLRYVIQKQRIMFIHEKKK"
     CDS             16390..16986
                     /locus_tag="ctg1_89"
                     /transl_table=11
                     /translation="MTACSNSTQTKNDSRPAQAVQNGIQQHVKGKGIVDIPGNYKGKLK
                     DLETVKGKVLHIKDGDTIDVNVKGQKQMVRLLLLDTPESVSQKIPPQKMGKEPSSFLKK
                     QLEGKSVTFVYDRGPKEDKYGRKLAYVFCDGIHINELMVKSGYGIIAYISRPNTTILSE
                     MKEAENEAKESKVGVWSIKGFVDEKNQHYNRKDAA"
     CDS             17038..17241
                     /locus_tag="ctg1_90"
                     /transl_table=11
                     /translation="MNENKRNMLLSFIISILFIFASLLPFSNNEYVYVISKIGAAAGVI
                     NIVMMSVFLYFQSKKTGHLLNW"
     CDS             17314..17526
                     /locus_tag="ctg1_91"
                     /transl_table=11
                     /translation="MSQVPGFLKFVLAKERRYVYLVVGEKKNKKVLTHMVYRFGSLEKA
                     LETMYEMRGDFENLFPLELKERGYD"
     CDS             17796..18095
                     /locus_tag="ctg1_92"
                     /transl_table=11
                     /translation="MGVGIYRKDSHVSTYAFPFACIGLMLSVYQITIQAFPNSEMQICS
                     VGVSCTKDYLNLFGFISIPMLSFVGFLAIIILLYIKSERDKRINNTAIMNNMLE"
     CDS             18155..18448
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 77.5; E-value: 9.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_93"
                     /transl_table=11
                     /translation="MTTMQVSNEMYKIPEADIELLKIMAHPVRLQIVKELEHHKICNVT
                     QLTELLDVPQSTVSQHLSKMRGKILRSERRGLEMYYHIVNSKACQIVGVLGI"
     CDS             18995..19408
                     /locus_tag="ctg1_94"
                     /transl_table=11
                     /translation="MREIAKKVKMIRLQEEHSGLKADAEQYSSKRCKIEREGINLEKNR
                     VKKRTQKFQTSEEKWDIKCKKAVQLFNQGEEYPTIAKNLRCNVSSLYRELKKRGTLQTP
                     KQVAVSKSLKSPITSTRTKKTNFERYKEYYMYK"
     CDS             20321..20719
                     /locus_tag="ctg1_95"
                     /transl_table=11
                     /translation="MKLDSNNHSVFLLYYHLVLVVKYRRNVFDDDMSDYAKDMFVRLSE
                     NYNITLVEWNHDVDHVHILFKAHPNTEMTKFINAYKSASSRLIKRDFPQVKKKLWKEMF
                     WSRSFCLLTTGGSPIDVVKTYIENQSEK"
ORIGIN
        1 tattagggag tgcaaatgaa gaactgcgat ataaatcatg tgatggtagt ttatacaggg
       61 gaaaaggaag aactaagtga tatgaatact tggagcttcc ttttttattg caattagaaa
      121 tctggtagat gattatgcat ataaaaatga tttggcggaa aaattttatt taatttcaat
      181 acatagaaga aaaagaaaaa aacaaattcg taaagggcta gtttaagtac gattcatttg
      241 aataattgag aggggaaatg tattggtgaa acgtcttgtt tcttgctgac caagggaatg
      301 caggatgatt agtaaggcgt aagagcgtat tactactctc acaaaggaaa ttacattaga
      361 aaagggtctg tcagtgttta caatttattt gttacatcgg tctaaaagaa tttggatgga
      421 gaagtaaatg ctaagtgaga acatgaatga catttctata acttgaacaa ttgtgctttt
      481 tgttaatagt gaaaatcaga agtagaagag gcacaagcgt taaagtggac tgcaaaagtg
      541 acagaaagag aacaaggatt aacattattt ataaagatat ctaataagaa gtgctatcgg
      601 atttatacag aaggagggat aataccagaa aatatatgaa tgtatataaa atttgaggtg
      661 aatccaccta ttttctatac attagttgaa tcaaacaata gatgactagg gagtgtataa
      721 catccatttc ccagttaaat tttcttagat aaatagcatg aaatacagta tgttctcact
      781 catttgtata aggataaaat agccttttat ttttatgcaa atgagtgaaa cagaacgatt
      841 caccatataa gaatattcga ctataatgaa acactgtacg tcattgtaat attaagatgt
      901 tttaagatta aagtgattat tagtcataaa atatgagttt cgagacctca gcaaaatatt
      961 gcaatgcttt atatacatga gattgtaaaa attattttat taaaattact ggaggctgat
     1021 gaaatatgat aatagatcat ataagcaaca atgtagtaaa aaaattggaa caaacggtgc
     1081 gctatgaaaa gaaacaggta caggtattac gtgtaagtaa aagtagttct aatatgcacg
     1141 cttacatgat tttcccagaa ttctcagagg ttaaaatttc aaatactgaa ctggatgaat
     1201 atatagaaaa tctatcaaca agtctgaaat atgtcattga tcgcaagtta agtctacaag
     1261 aaattgaaaa acaaaatcat tctttcatta tgacatgcgc agtcgaggaa gatggtgtta
     1321 tagatgatga aacgattcat tttaatacga cgtatgttaa gccacctaca cttgcgagta
     1381 aggtatttaa gctagtgtgt ggtttaggaa atcgtttgaa tagcttaaaa gagttacata
     1441 taacagtatt aaataataat attaatcgaa ttgaaataga gttttataat gaaaatgaaa
     1501 catatgtagc agtagaaaaa gaagaaattg caaatgcgat tatgggggca tatacaaaag
     1561 ccaatatcta ttattccgca gatctccgtt atgttgcaga aggaaatgaa atcaaattaa
     1621 agagcattaa gccaaaatta gcgggtgatg tgttgtgaag cgagaaaaag ggatgattgg
     1681 agttttatgt acatatgttt ttatgatcct agtactcata cctttacata cagctcatgc
     1741 atctgtaaaa atggatttta atgaattgaa aggaaatgat gtttcttcat cttttaacga
     1801 aggattaaac aatcgaacaa aaacgacaga gaaagacgat tcatttgggt catcaattat
     1861 acaaaaagtt gagggtatgt atgcaccagc ttttaaagta ggggtaaata tcttttctat
     1921 ctctttcata ttaggtgtta ttgtcatggt tatggggtta attacaaaga atggtcaatg
     1981 gatgaaatgg gcaacaggga gtatgatttt ctcgttcgtt agtatgatgg caatgagatt
     2041 aagtgtatat ttcttattta gttcggatgt attttcgttt atgaacattt ttacggattt
     2101 tttagacctg tttaaagcaa cagcacttat ttttacaccc tttatgttaa ttgcaggaat
     2161 tcgtttacga agaattcatg agagtacaaa acaacctgag tattatcgtt ggtctaatcg
     2221 cgttataacg ggatcttgtt tactatgtat gttagccgta ctggctccat ggttatttgc
     2281 gaatatgtaa agaaatatat atagatgcaa aaggtactga atgttcattc agtacctttt
     2341 atctacccat ctgatttttc ctttcatatt ctgcaaatat ctcctctgat ataggggata
     2401 atttgttcga tttttaattg tttttcgttg taaattattt ccatttgtag aatgaatact
     2461 cctcgtagta gagctggtat gcctacaaaa cagacgagga agatagaaac taaaataata
     2521 tttaaattag aaattcatac ctcgtattta ataataactt aatttatttt gataggagtg
     2581 cttgttttga aaagaaatcc agaatatacc gctttacgta attctatctt gataggttgg
     2641 ctgctcacaa ttattgttat gggcttatct atctattttt cttctattat atatttacta
     2701 attggatgtt ttattttgtc attgaaatat ggattaatgg gcactataaa gaatgtagaa
     2761 aagcgtttgc caacctgggc taattttgga gtgattgaaa aaacagtgaa tcggagggtg
     2821 acaagaccgt ttcaatttcg gggcggactc attgtttcat tagcattagg attcatagag
     2881 atggtgataa aaggtttatg tatctcatat tatattttag gattagaaac ccatgtatat
     2941 cgtttaatgc gtagaaacac aagaatgtga aaaggggact taaattatga aagtattaat
     3001 atttgaatta attctaattg tgcttctgat accgataaac attatggtaa aaaaacatgc
     3061 tccaaaatgg aaaggaagag ctggagaaaa gatggtaaaa cgtatagtaa gaaaattaga
     3121 tcacgaaagg tattgggtgt tacatgatgt ggcggttcat acagagtatg gtgatacaac
     3181 tcaaattgac catattgtta ttgcagaaac aggtatattt gttatagaga cgaagaacta
     3241 cgagggctgg atttatggaa gtgagaaggc agcaagatgg acacaaggta tttttagaaa
     3301 gaaacactct tttcagaatc catttagaca aaattataag cacatgaaaa caattgaatg
     3361 ggtgatggaa caacagctgc cgtgtatttc tattgcagcg tttcatccaa aatgcagcct
     3421 aaaaagagta aatgttcatt ctaaagataa acatgtccta tattataacg atctaaaaaa
     3481 atgtatcgaa tcctatattg atgtgaaatt aacaaaagac gaggtcgagc atatttacca
     3541 gactattttg caagcaaata ttactgataa ggatactgaa aataaacatg tgaagtattt
     3601 acagaataag ttcgctaaac aataagaaac ggagcaagga acaatgttat atataatagg
     3661 atttttggta atcatcgtag tagttattcg tcttaacgtg aagtattacc agttaaaagg
     3721 taatccaaaa gattttgtga tgaaaaagaa ggattaagga tttattttag aaatagaggt
     3781 aatagaatac atatattatt ttagccatca ccaaaggtca taagaaccgt tttacgatcg
     3841 ataaatacat acattactat attttattaa tgaatttaag tgatataata aataaaaata
     3901 aacaggaggt ttagttgtga aagaagtgtt agatgtagaa acgtatttaa agaaaatgaa
     3961 gaatcagaaa ataaattatg ataaagtatt aagaaaaatg attaatgatt gggaagcaag
     4021 gaacgaaaga ccaaaagtgt tacttcattc atgctgtgct ccttgtagta ctgcttcatt
     4081 ggaatttctt gcagaacatg cagatattac ggtttttttc tcgaattcga atattcatcc
     4141 gaaaagtgag tacatgcgac gctctaatga acaaaagatc tttgtagaaa agttcaatga
     4201 tcgtactggg cacacagtag gatttcttga ggatgactac cgttcaaatg tattttttaa
     4261 aatggtaaaa gaagaaggtt tggcagaaga gccagaaggc gggcttcgtt gttcagcttg
     4321 ttttgatatg agattggatc gttcagctga ggtagcacaa gaaaaaggtt ttgattactt
     4381 tgggagtgcc attactcttt ctaaaaataa aaatagtcaa ttaataaatg aacttggaat
     4441 cggtgtacaa aaaaattatg attcgcgtta tttaccaagt gatttcaaaa aaagtaatgg
     4501 atatcaacgt tcaattgaaa tgtgtaatga atatgatgtt ttccgtcagt gttattgtgg
     4561 atgttcattt gcagcagaga aacaaggtat agatttaaga tcggtgaaca aagatgcaat
     4621 acattatctg aaagaaaata atcttagttt aaaaaaatag atttaatgga gagaaattcg
     4681 atgtaagatt aacctatgat ttacaaacga aacgcattat gtttctaaag gaaaaacgta
     4741 aaaagctaaa atagttcggg aataactcct tactggttaa agttctagag aagaaaaaac
     4801 caataaggag tgttttctta atctcgcatt gcccctgcct ctcgggaagt cattgctcct
     4861 tgtcctgctc ttacatcatt ttgaatttct tgtttcactt tttgtgcatc tgtttcagca
     4921 aaatctggtt tcataacaga accaggactt tttatagatt ttttacgatc ttgcatacaa
     4981 cccctcctcg atttaacatt taacaatctt attatttaca aaaatacact cggtatactc
     5041 cgagtagtat aatgtttatt gaagaaaaaa ttgattacta taaggtgata gaggaacata
     5101 gggaataaca atcttgcatt aacatctctc tcaaaagttt agagaaatat ctgccagaaa
     5161 aacgcctttc tctctgtaga aatataaagg aagaatagtg tttttttatt ttggatacaa
     5221 tagtctaatt atgcaaataa ccacttgtta aggttattag taaaagtggg atccaagaat
     5281 gactaaatag ggaatctaat agatggatat ggaaaaattt aattcaatat aataaaaaac
     5341 ctttatttaa ggcgattaga cttgctttaa ataaaggttc catcaaaaaa tcactatcaa
     5401 ttgttagttt aaaaccaaat tgaagtgtat atattttatt gggaaatcgc tttatagaca
     5461 tcaagcaaac cattaccaaa aaaactttta ttagtagggg tatcattgct aactccattt
     5521 ttataaagat atctcacggc cttatctgga ttttttttaa aattattttt atcaataatt
     5581 aatgctaaag cacctgacac ttttggagcg gcaagtgaaa cccctataga gagagcatag
     5641 ccaccaccag gggcggtagt taatattagt tcttttaaca ttaacttatt ttttacccac
     5701 tgttctaaac catattgctg aaataatcta ttatctcctc caggtgcagc aatatctata
     5761 aaactttcac cataatttga aaataaggag agtaatttag atggaccaac agatgaaact
     5821 gttactatat ttggcaactc agcaggaaca tctaatactt ctccagtaaa tgttatccca
     5881 gtattttcat ttttttttct aaaaaaatca ttcatttcct gcttgttagt aacatcaaga
     5941 gcatcattac cagccgcagc aactatgata cttccctttg atttagcata tttaatggct
     6001 tttctataag ctttaatttc ggataattcc tcactagatt caccgtctga agaagatact
     6061 ataccattga tgaggtattc gcctaaactt aaattgataa catcaacatt atctttcgca
     6121 gcttcaacta tggctttaat aacccaaata gcctcacctg ctccattacc aaacactcta
     6181 tacattttaa ttccaatacc aggagcaacc cctttcataa aaccattagc tgcaacctgt
     6241 ccagcagtaa aagttccatg tcctcttaga tctattaggc gatttaattc acctgtttct
     6301 tgagattctt gctctctaaa tccaccttta ggtactaaat ttttagatcc aggtgaaatg
     6361 ttatctttta aatcaggatg atttatatca atgcctgaat caatgatacc aacagttaca
     6421 tttttagttc ctggatatag tctatagcta tcaccattat gggttacttg ttgcatatcc
     6481 cattgattct cccatatttc atttaagggt aggggggaag agacattggt tgctacttct
     6541 cttgaattaa acgattgtaa tgacttatta tatgaatcta tattaggatc cgaatgaaca
     6601 atattcattg ctttttcggt agctttcact tgtataacac caatctctgg gacactatag
     6661 actacttgca tatcatattt ttgaaactta ctagctagtt tttggttatt ttcatagttc
     6721 ttcaacatta tagtataata ttgtgattta ttttcagcat gaactgtagt aataggtatg
     6781 aaagttccgg aaatcaagtt aattaacaaa aggaatttaa ttattttttt cataaaatca
     6841 cctcttgata tattatgtat aatccttagt ttactaaatc gttaatgaaa agagatgtta
     6901 agggaattag tgatttgaaa aatttattca ctttgatatc gataaaatgt attttaggaa
     6961 taagttcatt agagaagaga attaaataaa agggaatgag taattaaata tataaagtat
     7021 ttaattactc attcctatga tttcaaattt aaattataaa tctttttttg catatacttt
     7081 cagagatatt atcattgata taaaaccaat aataattgag atgaaacaag gcatccatgt
     7141 taggacagtt ggtgagaatg gaaaaatact tttgaaatca atatcacttg attgtagtcc
     7201 ccttataaga gtaggagcaa caaaaggtat taaaaaagca gttaaaagtg atatgatttt
     7261 ggttttgtca taaccaaatt taaactgaac aggaagtagt acaccaaata aaatacttag
     7321 agttaaaaaa gttattccaa gagcgctagc gctcaggctt tctatacccg atggtgcgac
     7381 aactgaaatg attatacgga taatagctgc acaaataaaa attacaaaaa gaaaaaggta
     7441 cttcgctttt acaaatgcgc ttcgtgtgta tggggtagca caaagtaaag ccgctccctt
     7501 gtactgatcc tcaaatttgg ataccgttcc gaacaaaata tattccatca aaataacggt
     7561 taaaagaaag ctaacaagac cgccatcgtt taattgtaat tgtgaagaaa gataaatagg
     7621 agctatagca gcaaaaacga gtaagattag aaaatatttt ttgactaaca aaaagtcttt
     7681 catcactagg ttaattaaca tggatgttcc ccccaatata tgaaagcata atctcctcaa
     7741 tagttggtct ttctattaat acatcaggca tgagtcgacg tacatcatct tttttattag
     7801 taatcccttc aaatccatag tgagtttgat gtaaatttaa aaaaagaggt cttgtttgtt
     7861 tattaattaa gcggttgtcg ccctttacca atgcatgtgt atctattaaa acatcttttt
     7921 catcatttac taaaactttt ccatcatcaa ttaaaataat catatcagca attttatcta
     7981 aatcagatgt aatatgagtg gaaaaaaata cgcttttccc cggctctttc atgaaatcaa
     8041 ggagaatatc cattaattca ctccgtacta atggatccaa gccacttgtt ggttcatcca
     8101 ttattaatag atctgcatga tgggataggg ctaatgcaac tgcaaatttc attcgcattc
     8161 ctttggatag agtagagatt ttttgttcta gatttaagtt aaacttttta atataatttt
     8221 ggaaaactgt ttcatcccat tcagtgtagg atggagcaat aacatttttc atttccttta
     8281 ctgttaattc atcataaaaa tagccctcgt ctagcacaat accaattttg tttttagact
     8341 ttctttcatg cttatccata tcttttccta gaaaattaat tttcccagaa tcttttaaaa
     8401 taagacccaa aatcgcttta attgtagtgg tctttccaga accatttgta ccgataaatc
     8461 ctgttataca gtctgtatta agtgaaaagg taacatcttt taacgaaaaa tttccgtaag
     8521 atttatttaa attatttact tctaacacaa cattcatttt tcattctcct cctctaaaat
     8581 taaatctaaa attgaatgga gatcatctgc atgaatacct atactacgag ccatttgaca
     8641 aacttcagta agtttaactt ctaccatccg gcgtttggac tccattaaca actctaaatt
     8701 tgtaggagct acataggtcc cttttccaac ctttgtaata ataaagcctt ctgtttctaa
     8761 ttctgcataa actctttttg tagtaagtac acttacatgt aagtcgttag caagtgagcg
     8821 gattgatggt aattgttcac cctcttttaa ttcattgtta aatatggatt ccttaatttg
     8881 ctcctttatc tgttgatata aaggcagact tgatacatta cttaagacta ttttcattaa
     8941 acaacctctc tatcgataag tgttatgtta tgtaatgcac accatacaca ccatacacag
     9001 ttaacattat aaattataaa aagcagttta acaagatata ctgcgattaa ataacttttc
     9061 ataaataaaa tttttagtat cagttaataa agatatttgt tattttaaat aaaccaaaaa
     9121 gaaagttttg taaatatatg tcacaaaata ttaaagaaac acacacaaaa tgtttaaaat
     9181 tttttgattg tttttagaaa acatagggag ttatacttta gtcgcaccac acaatacaga
     9241 aaagggggta ggtcaaatgg aaacaccagt agtacaacca agggactgga cttgttggag
     9301 ttgtttagta tgtgcagcat gttctgtgga attattaaat ttagttactg cggcaacagg
     9361 ggctagtact gcaagctaat atcctttcag aagttttttg gttaaaagca ctaagagaat
     9421 gagcactttt ggtcaaatta gactttctag gagaaaaata aataatcaaa aaggagatgt
     9481 tctaaatgga aacaccagta gtacaaccaa gggattggac ttgttggagt tgcttagtat
     9541 gtgcagcatg ttctgtggaa ttattaaatt tagttactgc ggcaacaggg gctagtactg
     9601 caagctaata tccttttaga agttttttgg ttaaaggtac taagagaatg agcacttttg
     9661 gtcaaatgaa ttttctagaa gaaaaataaa taaccaaaaa ggagatgttc taaatggaaa
     9721 caccagtagt acaaccaagg gattggactt gttggagttg cttagtatgt gcagcatgtt
     9781 ctgtagagtt attaaatcta gttactgcgg caaccggagc tagtactgca agttaaaatt
     9841 ttaaaatgtg agagtgttta tggtgaaatt aaattaggac ttattctaat gacaaacagt
     9901 tatgttaaga ataagtccta tatatttatc gaaaacgagt atgggatttt tgtaatacat
     9961 aaactaaaaa caaatttaaa ttttatagga gatgattaaa gtgaatggct atttattttg
    10021 gaaagaaaag ctagaaataa gaaaattcac atcaaattat gaatctatgt tggtagttca
    10081 taaaaaccca aacgaaagcg ctcctacgct taaaaacgaa aatacattta cgataaataa
    10141 aaccgccact gaaattattg agttaattga tggtactaaa acatatggac aagttgtatc
    10201 tttcttgtct ttaaaataca gtgaagatcc aataagtatt gaaaagaaat taaatgcatt
    10261 tttaaataat gtatccaaag tttacaatat gaacattggt acgcaagaag aacctataaa
    10321 tgtaccagtt aatttaattg aagaacagac tatatatcca aaagtggctt caattgaaat
    10381 cacaaacaga tgtaatgtaa gatgtcgtca ttgctatgga gattttggag cagtaaagcc
    10441 aaaagtaatg agcttagatc aaataaaatc cttattagat gacttaaata atataggagt
    10501 gaaattaatt gaacttacgg gcggtgatat aacagtacat ccaaatctaa aagagatatt
    10561 gttatatgca cttaacttgg atttttctca aataacactg ttgaccaatg gtatagctct
    10621 ttctgagaaa gttatggaca taataataaa aaataagtcg aaaacatttg tgcaaattga
    10681 tatgcatagc ttagatgata attatttgac ttggttcttt aaagttccta atacacttca
    10741 taaaattaaa aataacataa tgaaattagc cgaaaatgat gttcgtttgc ggatcgccac
    10801 aatagttaca catttgaatg tgcacgaggt agaagatata gctgaatggg tacataattt
    10861 agggattgat agtattgggg tatctccagt aataccaatg ggaagagcct taggatgtag
    10921 tgatctttat ttaaatgaag aggatgttaa aacatatggt gaagcattgt tgaaaataaa
    10981 taaaaaatat cctaaatttg tttcattata tgaaggtgcg cgcgctgaga ttaggaattg
    11041 tggtgcaata acatcacata ttgtgattgc gcctgatggt gaaattaaaa tgtgtactat
    11101 gcatagttta gatgatttga aaaacagtat aggtaatgtt tttgaacaga atattaaaga
    11161 tatttatgac gaaaaattca aatacattaa tgcatttttt aacttgcaag cacctcaaat
    11221 ggactctgag gaatgtaaag agtgtgaaaa taaacgtttt tgtagtacat gcttcttaag
    11281 aagctttata aaagcacaag aaattggcga taaatgtaaa tggtttaaaa atcatgtccc
    11341 tgaaataatt aaggagccat taatggtagg gcaaaattag tatgattgga tgagatgaat
    11401 attgttaagt ttctgaggat aaaccaatat aattccatag acaatgcgtc gggataaggt
    11461 ctcaagatat ctatggaatt atataaacct cattatattg attcgtaaat taatataata
    11521 aatagacaaa ggaggagaaa gagggtgaat aagaagataa ataaacaaga tgaaattcaa
    11581 atttcttata aagagttatt atttttatat ccgtatttga aaaatacaaa aactttgtta
    11641 gctcttggtt taattgggat ggttatagct tctttgatta tcgcaccgat accatatatt
    11701 attggctaca ttattgataa agttatacta ttaaacaaaa gctacgatca attattaaaa
    11761 acaactctta tactcttatt aatttattgt attaactatt taatatcgat aggttatgag
    11821 tatttattta ctcgtgtaca acaaaatgta gttaatgaaa ttcgattatc tatgataagt
    11881 aatattatag atgcgcctct ttcttatatt aatcagaagg agaaaggtta cattcttagc
    11941 agaattgctg aatctggtaa tgtaagtgca ttattttctc caaatttatt aagggttttt
    12001 tcaggtatat tcgatttttt ctttgcttta tttataatgt ttaatttaag tgttaaactt
    12061 acaggtatca tagtaattat tatcccaata tattttataa tatccaaaca ttcttctaaa
    12121 atgatatcaa aaagtaccac aaacgtatac gagtcatcgg cagtattaaa cgcagaaatg
    12181 tatgaaacct taaatggaat agaggatata aaattattaa acggtaaaaa tatacaaacc
    12241 aataagatta agagtaaatt aaataatgta attaaaagtg cgctaaaaca aagtttacat
    12301 tttattttct ttatgcaaaa tttaatagta acaaataact ttgttacagt aatagtatta
    12361 ctggtatcag gtattttaat tttacaaaac cagcttacta taggggtgta tacttcattt
    12421 tcaatttata tggctaaact ccttgcgact acccaagctt taggcagctt agatataact
    12481 ctaaaacccg tgtgtattag tattaagaga attaaggagt tcttcaattt agatgttgaa
    12541 aatacactag gtacaaatat aatgaaagaa ccaattaatt caatagaatt taaagatgtt
    12601 tgttttaaat ataatggaaa tagtgatttg atatttgatc atttaaacgt gcaaattgaa
    12661 aagggtgaca agttattaat tgatggtata aatggatcag gaaaatctac ctttataaaa
    12721 ttattaacag gtttatatca acctgaaagt ggaaagatat tgataaataa tattgactat
    12781 aacttaatac ataaagaaag tgttagagat agaataggta tagtttcaca aaatatattt
    12841 ttgtttaaag gaactatatt agataacata ttatatggac aaacaaataa aacgaaagaa
    12901 gatgtagtta agttaatgaa aaggtatcat ttaacatcac atctcaacag atttgagaat
    12961 ggattagata ctataattgt acaagatggt tccagtgttt caggaggtca agcacaattt
    13021 atagcctttt taagggctat cctcacaaaa agggatataa taatattaga tgaagcagca
    13081 tctaatttac atattgatac aagaaatctt atgtatgaga tacttcaaaa ttacaatctt
    13141 tgtaatatat taattatgat ttcacatcag caagatggct tgtattttct caataaaaca
    13201 ttagaactta cacatggtaa taaaagaatt gctttaaatg gtagtatgct ttaatcatca
    13261 tgctttcata gaagggagca tcctaattat gtcaaaaatg aaacttatta attttgatac
    13321 atatagaaat tcaatagttt tatttgagaa caatggcgag attatatcag tgtcagctca
    13381 ttttcaattt tttgaaggaa gtgaaagcta tattcaaggt tttattgata atgaagaagt
    13441 tattcacttt aaatctaata atcctggtcc gaatatttct atatatcgat ttgcgcctaa
    13501 gaatattacc aaattaatta tatcaagtga aaatagaaca catggaatgg tcacattgta
    13561 tacttcagaa atatagctaa catctaaatt ttttaatagt taatacgatg aagtcttgga
    13621 ttaagatcgc ttgtataaca ttatttgttt ttaaatagca gctatataat caaaaaaaag
    13681 gaatccttta ttataaggta ttcttttttt tgattataat attaaattta ttatagggtt
    13741 tctttaccca tcggcattta actaaagcga aattgtaaac ctaaaataaa ataactttat
    13801 cctttcctat aattctacag aaagaaaagt gtattttttg caaaatgcat gtgatgtcac
    13861 gaataattaa aaggttattc aataaaaagc ttactgccgc atttaaactt attgaaagta
    13921 actaatttag ttatatatca atcaaccacg tccagcttgg aaagatggat atagcgacat
    13981 accaccatca gcaaacagtg taatacctgt tacatagctc gcttgtgaag aagcaagcca
    14041 tgctgctacc gctgcaattt ctttcggttc tccgatatat cccataggaa ccatactttc
    14101 aacatcggca cgtttttctg gatccgcaaa tttttcagca ttaatcggcg tattcatagc
    14161 accaggccca atattattta cacggattcc ttttggtgca tattctagtg ctaatgtttc
    14221 tgtcattagc ttaacgccac ctttacttgc tgcatagtgt acaaataatg gccatggaat
    14281 ttgctcgtga acgcttgaca tattaataac actaccttta atatcatgct caacaaaata
    14341 tttaattgct tcccggctcc ctaagaaagc ccctgttaaa ttcgtagcaa ttaccttatt
    14401 ccaatcactt aatggcattt catgtgaagg tactgaattt tcaatacccg cattattaat
    14461 catgacatcc agtgtaccaa attcttccac agcagattta acgagattga taacatctga
    14521 ttcaactgtt acatctcctt ttaccgcaat cgcttctcca cctgcttgtt taactacttg
    14581 tactacctca tttgcttctg attcgtttga ataataatta attacaactt tggcttgttc
    14641 ttctccaaaa cgaattgcca tcgctcttcc taatcctgtg gatgcacctg taataacaac
    14701 aactttccct tttaaatctg tatacataat tttttcctcc tttttatcct ttagcaattc
    14761 ctaacataat gccagctgca ataatgaaga taattccaat gacaatcgca ataaattgtc
    14821 gttttgtttt cttttcacct aatataaaaa ttccacctaa agttgagatc acgatcccca
    14881 tttgggaaag ggaaaaactt gttgccaccc ctacacgcgg ctgggaaata aataaaaaca
    14941 tatttcctgc tgcccaaatt aaaccaggaa taatattgtg aatcgcatat ttattaaatg
    15001 gttgatgctt aaaggttagt agaattccac ctaacaccat accaatggct tgtggtaata
    15061 acgctgacca tccgtctata ccgaataggc ggataattac cacatatact aagtaaccaa
    15121 gagttgaaat taataacatc acaatccctt ttttgaaatt tcctttttgt tcatcgtttt
    15181 tctcctcttt gctttggagg gatgtgagaa cgattccgat tatgatacaa agaagtgcca
    15241 gaacacctaa tacaacagat gttgttgttg accattcatg aaatacaatg accccaaata
    15301 aagtagtcga aactaattgc atccctgttg aaataggcat tgttttagaa accccaatta
    15361 aatcaatact tttcaattga ttggcttgtc ctaatgccca aaataggcca gatataatcc
    15421 cgataattat caccacgggc gtcaaaacgg gttttataaa aatataaaca ccgatagaaa
    15481 aaactagagc gccaagggta gttccaagta tttgactgta aggaccgcct cctagtttaa
    15541 cgttgaagag tacaatactt ccccaaaata aggctggtaa aatcgctaat aaaatatcca
    15601 tttttctaac cttcctaaaa catatttatt aagttgaatg cttgtacgag atagtatctt
    15661 tgtgtcgagg gaattatttt agaataagag aagtttttct acccgtaata tttgtttacc
    15721 caaaataaaa gataaataac atcatgttga aaaagaaaat aactagcacg aaataaaaaa
    15781 ggttattaga aagaatatga ccaatacaat ttcaagtttt gaaaatagga ataatggaga
    15841 aaaacttgat gcaaaattaa ggtatgttat acaaaaacaa cgcattatgt ttatacatga
    15901 gaaaaagaaa taatatcgta aaatctttaa tttcatatat aaatttaata agaagtatga
    15961 tatgatgaaa gtaacaaaat acatctaaaa ctatcttgca aaaggacaca cctacgcata
    16021 catatgcgat aggtgtgtcc ttttttattt gtttttaaga tttcaagact gaaaaggggg
    16081 atgtatattg tgtaccagta atatagcatc tactaatgtt tcttttgaaa aattgaaaag
    16141 tcaggaagag aatgaaaaaa acatagtgtc aatatgcccg aattgtaaga aacgctcatt
    16201 tagagtactt tataatgatt atccaaaatg gatacagtat tgcctatgtt gtaattatcg
    16261 agaagtaaat acaatagaga gtccgtttgt ttattagatg tagctattta cgtattttga
    16321 ttaggaggaa gaatttccga tatgaaaata tgaattaagg ctatttgtat aacatcattt
    16381 gtatttcaaa tgacagcatg tagcaattcg acgcaaacaa aaaatgattc gagacctgcc
    16441 caagcagtac aaaacggaat acaacagcac gtaaaaggga aaggtattgt tgatattcca
    16501 gggaattata aggggaaatt aaaagactta gagaccgtta aagggaaggt attacatata
    16561 aaagacggag atacaataga cgtaaacgta aaggggcaga aacagatggt aaggttactg
    16621 ttattagata cccctgagtc tgtatctcaa aaaattccac cacaaaagat gggaaaagaa
    16681 ccatcttcct ttttaaagaa acagctagaa gggaaaagtg taacatttgt ttatgatcgg
    16741 ggaccaaaag aagacaaata cggtagaaaa ttggcttatg tattttgcga tggaatacac
    16801 atcaacgaat taatggtcaa gtcgggttat gggattatag cctatatttc tagacctaat
    16861 actacaattc tatctgaaat gaaagaagca gaaaatgaag caaaagaatc aaaggttggc
    16921 gtatggagca ttaaaggctt tgtagatgaa aagaaccagc attataaccg taaagatgca
    16981 gcttaacacc ctaacccatt gcaatacaaa tatttgtgca aaatggaggt tttttgaatg
    17041 aatgaaaaca aaagaaatat gctcttatcc tttattattt caattttatt tattttcgcg
    17101 agtctattgc catttagtaa taatgaatat gtgtatgtta tctccaaaat tggtgctgca
    17161 gcaggtgtaa taaatattgt gatgatgagc gttttcttgt attttcaaag caaaaaaacg
    17221 ggacatttat taaattggta attaaagcta aatagttttc cttactcata tccttttaag
    17281 tttggtaagg aaagccgaaa aggagtgtga aaggtgagtc aagtacctgg atttttaaag
    17341 tttgttttag cgaaagaaag acggtatgta tatttagttg taggagaaaa gaaaaacaaa
    17401 aaagtactta cacacatggt atatagattt ggttcgctag aaaaagcatt agaaaccatg
    17461 tacgaaatgc gtggtgattt tgaaaatctt ttccctctag aattaaaaga gaggggatac
    17521 gactgagaag atatcaatga ttggatactt tctattgaaa cagggtactc gaaacacgga
    17581 aataaactag tcatatacta gcaaatgttt tgtattttaa aaaataggtg aggcgaaaat
    17641 aagatgttga tcattcaaaa gtatcacatt gtaattgctt ggacgatagc tactagtgca
    17701 atgttaatta gtttgttttt tagtgaatgg atgaagctgc cgccatgtga tttttgctgg
    17761 taccaaagaa tggccatgta tccattagta ttaatatggg ggtagggata tatagaaaag
    17821 attcgcacgt aagcacgtat gcatttccat ttgcgtgtat cggtttaatg ttatctgtat
    17881 atcaaattac aattcaagcg tttcctaata gtgagatgca gatttgttca gtaggagttt
    17941 cttgcacaaa agattactta aatttattcg gtttcatctc gatacctatg ctatcttttg
    18001 ttggattttt agctatcata atacttctat atattaaatc tgagagagac aaaagaataa
    18061 acaatacagc gattatgaac aatatgctcg aataaacaaa aaatacctat aaatagataa
    18121 aaatataaag aaattaaaaa aggagaaata aaaaatgaca acaatgcaag taagtaatga
    18181 aatgtacaaa attccagagg cagatataga actattaaaa atcatggccc atccagttag
    18241 attacaaatt gtgaaggagc tagaacacca caaaatttgt aatgtaacac agttaacaga
    18301 gctattagat gttcctcaat ctaccgtatc tcagcattta tctaaaatgc gtggaaaaat
    18361 tcttcgctca gaaagaagag gattagagat gtattatcat attgtgaatt ccaaggcatg
    18421 tcagattgtc ggagtattag gtatttaatt ctaaatcgaa ataggatgat agaaagagtg
    18481 ttgttaaata tagctgcaaa agatgatgta ctgcagaatg ataaattcac aagcttaaag
    18541 tttagtcctt ctaataatgg aggagctgac tgtggtgaaa aattgatata gaggttacta
    18601 aaaaagagtg cagtacatgt ctgcattctt tttctttgtg ccatagctat aatagataaa
    18661 gtattttgtt ttgtatgact ctgaataggg gatacagtgt tttgctatgc gaaaacgata
    18721 ttttcgactt tttaagcaaa ggggataatt agtttattga tgtgtatagt atgaattaag
    18781 gtttagaata ttctgtgtca atattatcaa tttactatag tttccaatta tgtaaaaata
    18841 gaattgatta taattttccg taaatattag attgaaaact attataaggg gaatgtgagt
    18901 atttatagct gtttataaac gatgattggg gatacagaca atagggtgat caagtactgg
    18961 tagaatttat caaacaaaat gaggtgactt taacttgaga gaaattgcaa aaaaagtaaa
    19021 aatgatacgt ttacaggagg agcattccgg gcttaaggca gacgcagaac agtattcttc
    19081 caagcgatgt aaaatagaaa gagagggtat taatttagaa aaaaatagag ttaaaaaacg
    19141 aactcaaaaa tttcaaacgt cagaagaaaa atgggacata aaatgtaaaa aagcagtaca
    19201 attatttaat caaggagagg aatatccaac tattgcaaaa aatctgaggt gcaatgtgag
    19261 tagtttgtat agagaactta agaaacgggg cacattacaa acaccaaagc aggtagcagt
    19321 atctaaatca ttaaaatcac ccataacatc aacacgaaca aaaaaaacaa actttgagag
    19381 atataaagaa tattatatgt acaaatagaa gaattcatgg ctataaatct atacttaatt
    19441 ctttagtgtt aaaaagctca gattataaaa ggtacaatga aaaaatgcat gtttagcagc
    19501 aaatcttctt acagtattga tagagcatct ttttattttt taggatattt ttaaatctaa
    19561 caaatattga aggctattac ctgttgctta gatcaaaaaa atattcttaa aactaaatcc
    19621 ttacttatat ttgttgagta gttggttaag aagaggtttt tttgcaaatg ctaaaataag
    19681 gatactttgt ccaaagcaaa agaatcccca tgtcataaag gattctttta ggagagttag
    19741 agagatgttg tcacttgact catattgatt ttacgataaa aagaaagaat attcaaattt
    19801 attatatatt tctcaatata tttcttttat ttttatatta taattaattc tttttattga
    19861 tgtatatctt tctgtggtga atccttttaa taaggattcc ttttttagtg gctcatatat
    19921 taataatgag ccactagagt ttaagatagt ttatacaaca actattgaaa ttgcttgatt
    19981 ataggggaat tgttgatttc tattgctggg gatcagccct gaaaatttat ctacagtaat
    20041 aatgattaca ggtattctaa cttcgttgat tagaaaattt gttattactc tttttaaata
    20101 ttttaatctt tttaagtttc tcttatagat gtaaaaggtt tggtgtaatt ataatgtttt
    20161 taacgaattt ccggaaagaa ttctccttcc tcaagcgtgt gaagggcgta gcccaacggt
    20221 aggtgggaga tgaatttcgg tttggcgtag ccaaaaggtt ttccttttta ttttgcctct
    20281 gatataatca gtcttataaa ttataagggc tggtatataa atgaaattag atagtaataa
    20341 ccattcagta ttcttgttat attatcacct tgtgttggtc gtgaaataca gaagaaatgt
    20401 gtttgatgat gatatgtcag actatgcaaa agatatgttt gttcgactat ctgaaaacta
    20461 taacatcacg ttagttgaat ggaatcatga tgtagaccac gttcatattt tgttcaaggc
    20521 acaccctaat acagaaatga caaaattcat caatgcttat aaaagtgcaa gttctcgact
    20581 tattaaaaga gactttccac aagtgaaaaa gaaactttgg aaagagatgt tttggtcaag
    20641 aagtttttgc ttgctaacta ctggtggttc gccaatagac gtagtaaaaa catatattga
    20701 aaatcaaagt gaaaagtgag gtgaaatgat atgacaaagc agaataaagc atataaattc
    20761 cgtttgtatc caacagaaga ccaagcacat cttatgcgta aaactttcgg ttgtgtacgt
    20821 ttcgtgtata acagaatgtt agctgaacgg aaagaagcgt atgaaaaaca taaagatgat
    20881 aaggatcaac taaagaaaca aaagcttccc actcctgcga aatacaaagc agaatttgag
    20941 tggttaaaag aagtggattc attagccttg gcaaatgctc aactaaactt gcaaactgcc
    21001 tataaaaatt tctttcgtgg tcaaaatgac ttcccaacat tcaaaagcaa aaaagacaga
    21061 aagtcttata caacgaatgt agtgaacgga aatattatgt tgcttaacgg tcatatcaaa
    21121 ttgccaaaac tgaaaatggt acgtatcaaa cagcatagag aaataccaca agaccatata
    21181 attaagtcat gtacgatttc tatgacacct actggtaaat actatgtgtc cattttgact
    21241 gaatacgaaa aagagatcgt acaaaaagaa gtagaaacag ttgttggatt agactttgcg
    21301 atggaacaat tatacgtcag ttctgaggat gagagagcca attatcctaa gttctatcgt
    21361 gaaatgttag accgattagc
//
