LOCUS       NC_005004.1            12227 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_005004.1 Staphylococcus epidermidis ATCC 12228 plasmid
            pSE-12228-05, complete sequence.
ACCESSION   NC_005004
VERSION     NC_005004.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 17:22:38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12227
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12227
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[508:2227]"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      509..2227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..12227
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12227
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(195..449)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MIRKLNKKDQEILKTLGSIWLNSNIATHNFINEEYWVNNYDNVIE
                     SFKTAEIIVYEKNTEIIGFCGLIDNYIAGMFIKKSSRNQ"
     CDS             509..2227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     39.1; E-value: 3.8e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="Pkinase (E-value: 1.6e-12, bitscore: 38.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.7e-47, bitscore:
                     151.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKANYPAKIYDSFSAWEHKFIVEEYIEGDSLSIWMVNKYPFSSES
                     NNENYVKSSINILNQLIKAIKELHNLNIGFGDLQPANIIVSKEEKIRLIDFETAGSIND
                     SLSSVMTPGFIGSPKMNKGQGDWFAVLRIAKQMFIPIGSVQDISHNLDSVHNSWIKSTF
                     GQEALHIIKKIENICKYQNSRPMKEFITSQNKTVRNFNLLSVKEKLINCIKNDLRDEEL
                     LMHGDIRQYEMNSGKWNVLTGGFGVIMAVKRSGEWDEKFDKWIKSIDYSNLGYLENGLY
                     TGKIGIANVLIESGYIKEAATIIKTINIEDSNQDISLASGLSGLGLGFLSIYYELKENI
                     YLDESKKIGEMLENNFQDNTPVYTFDYDIVDKGFLTGWSGASLFMSCLYRATNNEKWLH
                     LSRKMLNKELEKTLFDDTGLFQVDDDFRILPYLSSGGAGLAIPMIAYESIVNESIWRKE
                     LEGISKIAKSKTFFNGGLFQGTTGIVAISNLLDNYLNKEDLTKSSLFTLNLHLIETENC
                     IYLPGDSCFRVSSDLMSGTAGLLTVVDDIINNSYFSWLPLLNIDKLINLDKITRR"
     CDS             2237..2362
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MKNVLDLQQMRSKAGKKKPTRKQSSTSWGCAPSSNTSWFFC"
     CDS             2401..2520
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MNKVLSLQQETVSKEVQLKAKSSKSQNCKNSSHSSWFIC"
     CDS             2578..4305
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 261.8; E-value:
                     2.2e-79)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MELFNLNVYNILKIAIDNKSKKIYLAVIIIISLIFTLASLYFPLI
                     IKNIITELEKNKVSVFIICYLILFLILRSVMESINEYLIAKLGNIVIKDLQQNIYDRIV
                     NYPISFFDEYNSGDLSSRLVNDTEVIKDLITFHIPKVINGLVMIVGAVCLIVLLDWKLT
                     VLILLISPVIFGIIFPLMKKLENTGEIQQNEISNFISKTQETFKNIRMVKASTAEQSES
                     KSISRYINNLFKVNLYESKVMSLVSPLVNLLLIFGLLIIAGYGAYRIQNDTLTLSTLIA
                     FIIYSFQLMSPISSISSFIGEYHKSNGAFKSLTVILSKDIENAKNTYKYNFKLEDKLIF
                     DNVSLEFKEKKILDNISFKLNKGESLTIIGPSGSGKTTLLNVIEKFYYINSGSITIDGI
                     DINDINTQNLRYNIGLVSQDIPIISGTIKDNLLYGLNNVSITNFEIKDILKSTMLKDLV
                     INQIDGINSYVGESGNRLSGGEKQRINIGRVLLKNPNIILLDEATSNLDNESKSEIINS
                     ISEITQDKTVLKITHNMHELKEDEQILFIENGKIIFKGKHGELLKNNERYKKFIKNEA"
     CDS             4385..4708
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MNIQFKKGALELLVLLIVKQEDQYGYSLSQIITNRIAISEGTIYP
                     LLRKLVREEYLESYYTPSKEGPSRKYYSITSKGNVRLNLLLREWNNFTEAINMFVKESG
                     LHE"
     CDS             4701..5270
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MNKEEYLRIIKKGIKKVDAKEKEDILNEYESHFISGYKDNKDDTE
                     IIKELGNPIKVAKEINAVNSIYKIEKEKSVKSIFSAAFSIMGLSIFNLFLIIISFFIFL
                     LLLPFVLAYFIAVPIMIFSPIILLVMGCINGFDTINTGDIFEVIKGVVLGIILAFIGYF
                     IAKYFLKLLVLYLNWNIDVYKKEKLK"
     CDS             5267..5878
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MKYIYIYLLLIFSIILVSCSNSIDNNNSKENSEDKIVEKPLPKKI
                     FDKNKDGQYITENEIRKSIKLYLDKNEELSEASEYYEDKIDSEESLSQNEIKKLKKLNN
                     LNQKNDENFKSYIKSNKLPKSYRKDTERISKYISHSNKYSQNLEKKIDKIIDKGINQKK
                     VSIKDIGKIENDSTIVNGREQSKIEKFLNEKNIKTKAFKK"
     CDS             complement(6442..6921)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MIIGYARVSSIDQNLERQLENLKTFGAEKIFTEKQYGKSIENRPV
                     LQEALNFVRMGDRFIVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGHLLLYSPNAKNP"
     CDS             complement(7261..8106)
                     /gene_functions="resistance (resist) PC1 (Score: 603.1;
                     E-value: 3.9e-184)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MKKLIFLIVIALVLSACNSNSSHTQELNDLEKKYNAHIGVYALDT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKIHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQHLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
     CDS             8309..9970
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MLNYKVWYLTLLAGLIPFIPIKFSFFKFNNVNNQAPTVESKSHDL
                     NHNINTTKPIQEFTTDIHKFNWDSIDNICTVIWIVLVIILSFKFLKALLYLKYLKKQSL
                     YLNENEKNKIDTILFNHQYKKNIVIRKAETIQSPITFWYGKYIILIPSSYFKSVIDKRL
                     KYIILHEYAHAKNRDTLHLIIFNIFSIIMSYNPLVHIVKRKIIHDNEVEADRFVLNNIN
                     KNEFKTYAESIMDSVLNVPFFNKNILSHSFNGKESLLKRRLINIKEANLKKQSKLILIF
                     ICIFTFLLMVIQSQFLMGQSITDYNYKKPLHNGYQILDKSKIFGSNSGSFVMYSMKKDK
                     YYIYNEKESRKRYSPNSTYKIYLAMFGLDRHIINDENSRMSWDHKHYPFDAWNKEQNLN
                     TAMQNSVNWYFERISDQIPKNYTATQLKQLNYGNKNLGSYKSYWMEDSLKISNLEQVIV
                     FKNMMEQNNHFSKKAKNQLSSSLLIKKNEKYELYGKTGTGIVNGKYNNGWFVGYVITNH
                     DKYYFATHLSDGKPSGKNAELISEKILKEMGVLNGQ"
     CDS             9960..10340
                     /gene_functions="resistance (resist) blaI (Score: 275.2;
                     E-value: 3.8e-85)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MANKQVEISMAEWDVMNIIWGKKSVSANEIVVEIQKYKEVSDKTI
                     RTLITRLYKKEIIKRYKSENIYFYSSNIKEDDIKMKTAKTFLNKLYGGDMKSLVLNFAK
                     NEELNNKEIEELRDILNDISKK"
     CDS             10604..11197
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTHGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNKLEDKEDEKQGEVSN"
ORIGIN
        1 agctgaacta gaagaaatac atacgttgaa tatgcgccgt caaaatatgc cgaaatacaa
       61 tatatttaat gaataattca aataatctga taacaacaaa gagaattcat cggttaaatc
      121 atcaaaaaaa tagaagtttt gtaatatgtt aagtgtgttt atctttgggg ttttacctat
      181 atttgttttg attgctattg gtttcttgaa ctctttttaa taaacattcc tgcgatatag
      241 ttatcgatta aaccacaaaa tcctataatt tctgtgtttt tttcgtatac gataatttct
      301 gccgttttga aagattctat aacattatcg taattattaa cccaatattc ttcgttaata
      361 aaattatggg ttgctatatt agaatttagc cagatacttc ctaaagtttt taaaatttct
      421 tggtcttttt tatttaattt acgtatcatt ttttatcacc ttgattttga aacgagttga
      481 aaacgaaggg aaagtattga agaagcttat gaaagcaaat tatccagcca aaatatatga
      541 ttctttttca gcttgggagc ataaatttat tgtagaagaa tatatcgaag gagattcttt
      601 gtcgatttgg atggttaaca aatatccatt ttcatcagaa tctaataatg aaaattatgt
      661 aaaatcttca attaatatct taaatcaatt aattaaagct ataaaagaac tccacaattt
      721 aaatataggt tttggagatc ttcaaccagc taatattata gtaagtaagg aagaaaaaat
      781 aagattaata gattttgaaa ctgcaggttc tattaatgat tcattatcca gtgtaatgac
      841 tcctggcttt ataggtagtc ccaaaatgaa caaaggccaa ggagactggt ttgctgtact
      901 aagaattgct aagcaaatgt ttattcctat aggaagcgtc caagatattt ctcataattt
      961 ggacagtgtt cataatagtt ggattaaatc aacttttgga caagaagctt tacatattat
     1021 aaaaaaaata gaaaatatat gcaaatatca aaattctaga ccaatgaaag aatttatcac
     1081 ttctcaaaat aaaacagtca gaaattttaa tttactatct gttaaagaaa aacttataaa
     1141 ttgtataaag aatgatctaa gagatgaaga attgcttatg catggagata taagacagta
     1201 tgaaatgaat tctggtaagt ggaatgtttt gactggtgga tttggtgtga ttatggcggt
     1261 taaaagatct ggagaatggg atgaaaaatt tgataaatgg attaagagta tagattactc
     1321 caatttgggg tatttagaaa atgggttata tactgggaaa ataggtatag caaatgtact
     1381 aatagaatct ggatatataa aagaagcagc aacaataatt aaaactatta atattgaaga
     1441 tagcaaccaa gatatttcat tggcatcagg tttaagcggt ttaggtttag gttttttaag
     1501 tatatattat gagcttaaag aaaatattta tttagatgaa agtaaaaaaa taggtgaaat
     1561 gcttgagaat aacttccaag ataatacacc tgtgtatact tttgattatg atatagttga
     1621 taaaggattc ctaactggtt ggtcaggtgc ttctttattt atgtcatgtt tatatagagc
     1681 aactaataac gaaaaatggt tacatctttc tcgtaaaatg ttgaacaaag agttagaaaa
     1741 gacattattt gatgatactg gattatttca agtagatgac gattttcgta tactgcctta
     1801 tctatctagt ggtggcgctg gtttagcaat acctatgatt gcatatgaaa gtatagtaaa
     1861 tgaatcgata tggagaaaag agttagaagg tatatcaaaa atagctaaaa gtaaaacatt
     1921 tttcaatgga ggattatttc aaggtactac cggtatagta gctataagta atttattaga
     1981 taactattta aataaagaag atttgactaa gtcttcttta tttacattaa atttacattt
     2041 aattgaaaca gaaaattgta tttatttacc aggagattca tgttttaggg tttcatctga
     2101 ccttatgtca ggaactgcag gattgttaac agttgttgac gatattatta ataatagtta
     2161 tttttcatgg ttacctttac ttaatataga caagcttata aatttagata aaattacaag
     2221 gaggtgaagt tggtatatga aaaatgtatt ggatttacag caaatgagaa gcaaagctgg
     2281 taaaaagaag ccaacaagaa aacaatctag tactagttgg ggatgtgctc cttctagtaa
     2341 cactagttgg tttttctgtt aattttgtgt gatattcctg attaaggagg tgagttaact
     2401 atgaacaaag tattatcttt gcaacaagaa acagtttcaa aagaagtaca attaaaagct
     2461 aaatcttcaa aaagtcaaaa ctgtaagaat agtagtcatt ctagctggtt tatttgctag
     2521 aaattaaaag aggcaataag atcgtattaa aaatactatc ttattgtctc aatttttatg
     2581 gagttgttta atttgaacgt atacaatatt ttaaaaatag ctattgataa taaaagcaag
     2641 aaaatttatt tggcagttat aattatcatt tctttaattt tcacattagc ttctttatat
     2701 ttccctttaa taataaaaaa tattataaca gaacttgaaa aaaataaagt gagtgttttt
     2761 attatttgct atttaatttt gtttttaata ttaaggtcag ttatggaatc tataaatgag
     2821 tatttaatag ctaaacttgg aaatatagtt ataaaagact tacaacaaaa tatttatgat
     2881 cgaatagtaa actatccaat atcatttttc gatgaatata atagtggaga cttatcaagt
     2941 agactagtaa acgatacaga agtaattaaa gatttaataa catttcatat tcctaaagtt
     3001 attaatggat tagttatgat tgttggggct gtttgtttaa tagtgttatt agactggaaa
     3061 ttgacagtac taattttact tatatctcct gtaatatttg gaattatatt tccattaatg
     3121 aaaaaattag aaaatacagg agagatacaa caaaatgaaa tctccaattt tatatcaaaa
     3181 actcaagaaa catttaaaaa tattaggatg gtaaaagctt ctactgcaga acaatctgag
     3241 agtaaaagca tttctagata cataaataat ttatttaaag taaatttata tgaaagtaag
     3301 gttatgtctt tagtatctcc tttagtgaac cttttactta tttttggctt actaattata
     3361 gctggatatg gcgcatatcg aattcaaaat gatactttaa ctttaagtac tcttattgca
     3421 tttataattt actcattcca gttaatgagt cctataagtt caataagtag ttttatagga
     3481 gaatatcata aatctaatgg agcttttaaa agcttaactg ttatccttag taaggatatt
     3541 gaaaatgcta aaaatacata taaatataat tttaagttag aggataaatt aatatttgat
     3601 aatgtaagtt tagaatttaa agaaaaaaaa atccttgata atatctcttt taaattaaat
     3661 aaaggggagt ctcttacaat tataggtcct tcaggatctg gaaaaacaac attattaaat
     3721 gtaatagaaa aattttatta tataaacagt ggaagtataa ctatagatgg tatagacatt
     3781 aatgatatca acactcaaaa tttaagatac aatataggat tagttagcca agatatacct
     3841 attataagtg gtacaataaa agataattta ctatatggat tgaataatgt aagtattacc
     3901 aattttgaaa ttaaagatat tttaaaatct actatgctaa aggatcttgt tattaatcaa
     3961 attgatggta ttaatagtta tgttggagaa agtggtaatc gtctttcagg cggcgaaaaa
     4021 caaagaatta atatagggag agtactttta aaaaatccta atattatttt attagatgaa
     4081 gcaacttcaa atctagataa tgaatccaaa tctgaaatta ttaactctat atctgaaata
     4141 acacaagata aaactgtttt aaaaataaca cacaatatgc atgagttaaa agaagacgaa
     4201 caaatattat ttatagaaaa tgggaaaatt atttttaaag gaaaacatgg tgagttgctg
     4261 aaaaacaatg aaagatataa aaaattcatt aaaaatgagg cttagtactt tacctatagt
     4321 ttaaaataag gtattatact atatacagta gttagtataa cttatatgag aggggcatta
     4381 tttaatgaat attcaattta aaaaaggcgc cttggaatta ttagttttat taattgtaaa
     4441 acaggaagat caatatgggt actcattaag tcaaattata actaatagga tagctatatc
     4501 tgagggtact atatatcctt tgctacgtaa gcttgtaaga gaagaatatt tggaaagtta
     4561 ctataccccc tctaaagagg ggccttcgag aaaatattat agtataacta gtaaaggtaa
     4621 tgtacgttta aatttactac tcagagaatg gaacaacttt actgaagcaa taaatatgtt
     4681 tgtgaaagag agtggtcttc atgaataaag aagagtattt aagaataatt aaaaaaggaa
     4741 ttaagaaagt agatgctaag gaaaaagaag atattttaaa tgaatatgaa tcgcatttta
     4801 ttagtggata taaagataat aaggatgata cggaaattat taaagagtta ggtaatccta
     4861 taaaggtagc taaagagata aatgctgtaa attcaatata taaaatagaa aaggaaaaaa
     4921 gtgttaaaag catattttct gcagcatttt ctattatggg acttagtatc ttcaacttat
     4981 ttttaataat aattagtttt tttatttttt tattactctt accttttgta ctagcttact
     5041 ttattgcagt tccaataatg attttttcac caataatatt attagtaatg ggttgtataa
     5101 atggctttga cactattaat acaggagaca ttttcgaagt tattaaaggg gtagttttag
     5161 gaattatatt agcctttatt ggttatttta ttgctaaata tttcttgaaa cttttggttc
     5221 tttatttgaa ttggaatata gatgtatata aaaaggagaa attaaagtga aatatatata
     5281 tatatattta ttattgattt tttcaattat tttagtgagt tgctctaatt ctatagataa
     5341 taataattct aaggaaaata gcgaagataa aatagtagaa aaaccattac ctaaaaaaat
     5401 atttgataag aataaagatg gacaatatat aacagaaaat gaaattagaa aatcaataaa
     5461 actgtattta gataaaaatg aagaattatc tgaagctagt gaatactatg aagataaaat
     5521 agattctgaa gaatcgctga gtcaaaatga aattaaaaaa cttaagaagt taaataattt
     5581 aaatcaaaaa aatgatgaaa attttaaaag ctatataaaa agcaacaaat tacctaaaag
     5641 ttacagaaaa gacacagaaa gaataagtaa atacatttct cattctaata aatattccca
     5701 aaatttggaa aagaaaattg ataaaataat agacaaaggt ataaatcaaa aaaaagtatc
     5761 aattaaagat attggaaaaa tcgaaaatga tagtacaata gtgaatggaa gagagcaatc
     5821 taaaatagaa aaattcttaa atgaaaaaaa tattaaaact aaagccttta aaaagtaatt
     5881 acttattcat caacttttta tttttacagt tagaatcaca ataatttaaa tcacaaacca
     5941 cccgtgtgaa cgggtggttt gttctacgtt tataaacctc ttttattggc cagcccaaaa
     6001 ggacactgac aggtcagtca actgcactac tttcccatca caccccctaa aagggtacta
     6061 tttttttcgt ctttttttaa tttcttctcc tgtaaatgga cctatgtatt cttctattga
     6121 aatttgatct gcaacgatat tctcttgtaa ttgattacga atgtaatttt caattacctt
     6181 tttattgcta cctactgtat ctacataaaa tcttttacac caaaactatc tatttccata
     6241 tctatatttt aaattgactt gtctatcaaa aattattaaa atactttcac cttttaaata
     6301 tccaacaaat aatgatgctc ttcatttagg tggaatactc actaacatat gaatatgatt
     6361 tttacatgct tctccttata ttatttctat gccttttcct tcttctaaca tttctgcaac
     6421 tcgataatag ataatacgtt tttatggatt tttagcgtta ggagaataca ataaaaggtg
     6481 ccctttatat acaccttttt ctttcgcaac ttgaatacct tgtgcttgtc tacgtttact
     6541 ttcatttcgt tcttgttctg aaaccattgc tagtatttga atgattaggt ctttcataaa
     6601 tttatctaat aatggattac cgatcacttc attcatcata ggtaagctag taatcatcaa
     6661 ttgaacttct ttatctttta aataattaac tgtgttaatc acctcatcat aattacgacc
     6721 taaacgatca atggattcta ctataaatcg atcccccatt ctcacaaagt taagtgcttc
     6781 ttgaagtacc ggtctatttt caatagattt cccatactgt ttttctgtaa atattttttc
     6841 agcaccaaac gtctttaaat tttcaagttg cctttctaaa ttttgatcga ttgatgacac
     6901 tctcgcataa ccaataatca ttgatttcac ctcataatta atatacaccc taatcatacg
     6961 tttaagttac ttgtcacttt gcttgatata tgagaattat ttaaccttat aaatgagaaa
     7021 aaagcaacgc actttaaata agatacgttg ctttttcgat tgatgaacac ctataattaa
     7081 actattcatc tattatttat gattttttgt atatacaata tttctagttt gttaaagaga
     7141 attaagaaaa taaatctcga aaataataga gggaaaatca gtttttgata taaaaattat
     7201 acatgtcaac aataatacaa actataagat gatatcagta tttattatgc atttagaata
     7261 ttaaaattcc ttcattacac tcttggcggt ttcacttatc aacttatcat ttggcttatc
     7321 acttttattg tctttattcg taaaaatgac taaaacaata ggttcagatt ggcccttagg
     7381 ataaacaaaa gcaacatcat ttctagaagc atatgttatt gcttgaccac ttttatcagc
     7441 aaccttatag tcttttggaa caccatcttt aattaaagtg tctccgtttt tattattaaa
     7501 cattaaatca agtaagaaat ttttattttt tttgcttaat tttccatttg cgataagttt
     7561 atttaaagtc ttgccgaaag cagcaggcgt tgaagtatct tttttgctct ttggtgaata
     7621 gtaatttaat tctatctcat atctaactgg atttgttact ttatctccta gttcttttag
     7681 atgttgttta acttttttga ttccaccgat ttcttttata attttattgt ttgctgtatt
     7741 atcactatat gtcattgaag cctcaataag ttcttttaaa gtgatatctt ttcctacata
     7801 tttttctaaa ataggagaat aagcaactat atcatctttg ttaatatgta tttttttatt
     7861 taacttatta taaggtactt gttctaacaa aatagcacta tttatcgctt ttgaagtcga
     7921 agcataggca aatctcttat ctgaattaaa ttttacttcc ttaccacttt tagtatctaa
     7981 agcataaaca ccaatatgag cattatattt tttttctaaa tcatttaact cttgggtatg
     8041 tgaactgttt gaattacatg cacttaaaac taaagcaatt acaattaaaa atattaactt
     8101 tttcaaaata aaccctccga tattacagtt gtaattttta taaatcaata atattacaat
     8161 tgtaatatcg gtgtcaatag tttattataa atatttgaaa gaaggtgttg aaatggctaa
     8221 gttattaata atgagcatag taagcttttg ttttatattt ctattgttat tattttttag
     8281 gtacatatta aaacgctatt ttaattatat gttaaattat aaagtttggt atctaactct
     8341 tcttgcagga ttaattcctt tcattcctat taaattctct ttttttaaat ttaataatgt
     8401 gaataatcaa gcgcccacag ttgaaagtaa gtcacacgac ttgaaccata acataaatac
     8461 caccaaacct attcaagagt tcacaacaga tatccataag tttaattggg attcaattga
     8521 taatatctgc acagttattt ggatagtttt agttattatt ttaagtttta aatttttgaa
     8581 agccttatta tatcttaaat atttaaagaa acagtcactt tatctaaacg aaaatgaaaa
     8641 aaataaaata gatacgatac ttttcaacca tcaatataaa aaaaatattg tgattcgaaa
     8701 agcagagact attcaatctc caataacttt ttggtatggg aaatatatta ttttgattcc
     8761 tagttcatat tttaaaagtg taattgacaa aagactaaaa tatataatat tgcatgaata
     8821 tgctcatgct aaaaatagag atactttaca tttaattatc tttaatatct tctctattat
     8881 tatgagttac aatccattag tacatattgt aaaaagaaag ataattcatg acaatgaagt
     8941 agaagccgat agatttgtcc ttaataatat taacaaaaat gaatttaaaa cttatgcgga
     9001 atctattatg gactccgtat taaatgttcc attttttaat aaaaatatat taagccattc
     9061 atttaatggt aaagagtcat tactcaaaag aagattaatt aatataaaag aagccaatct
     9121 gaaaaaacag tccaaattaa ttctaatttt tatttgtatt tttacttttt tgctcatggt
     9181 aattcaaagc cagtttttga tggggcaatc cataactgat tataattata aaaagccctt
     9241 acacaacggt taccaaattt tagataaaag taaaattttt ggttcaaata gtggatcttt
     9301 cgtcatgtac agcatgaaga aagacaaata ctatatttat aacgaaaaag aaagtagaaa
     9361 aaggtattct cctaattcaa cttataaaat ttatttagct atgtttggac ttgaccgaca
     9421 tattataaat gatgaaaatt cacgtatgtc atgggatcat aagcattacc cttttgatgc
     9481 ttggaataag gaacaaaatt taaatacagc aatgcaaaat tcagttaatt ggtacttcga
     9541 acgtattagc gatcaaatac caaagaacta tactgcgact caactcaagc aattaaatta
     9601 tggtaataaa aatttgggaa gttataaaag ctattggatg gaagatagtt tgaaaatatc
     9661 taatcttgaa caagtaatag tttttaaaaa tatgatggaa caaaataacc attttagtaa
     9721 aaaagcaaag aatcaattat cttcttcatt attgattaag aaaaatgaaa agtatgaact
     9781 gtatgggaaa acaggtacag gtatagtaaa cgggaagtat aataatgggt ggtttgtagg
     9841 ttacgtaatt acaaatcatg ataagtatta ttttgctaca catttatcag atggaaagcc
     9901 atctgggaaa aatgctgaat taatcagtga aaaaatatta aaagaaatgg gtgttttaaa
     9961 tggccaataa gcaagttgaa atatctatgg ctgaatggga tgttatgaat ataatatggg
    10021 gtaaaaaatc agtatcagct aatgaaattg tagttgaaat tcaaaaatat aaagaagtta
    10081 gcgataaaac gattagaaca ttaatcacaa gactatataa aaaagagatt ataaaacgat
    10141 acaaatcaga gaatatttat ttttactcat caaatattaa agaagacgat attaaaatga
    10201 aaactgctaa aacttttctt aataaactgt atggagggga catgaaaagt ttagtgctga
    10261 attttgcgaa aaatgaagaa ttaaataaca aagaaattga agaattgcga gacattttaa
    10321 atgatattag taaaaagtaa ttagagatat gtttcaaaca taatacatat gtaaactatg
    10381 cttgactctt attaaattag ttttgttaat aacatttaaa atatattatt aaagatgaga
    10441 gtgtacagaa aataaccatt ttctgtacac tcgtttttta tgtctaaata agtatgtatt
    10501 acatagaatt atgtgttcaa aaacccaaca aaaaatctat gttcacaaaa gaccttgtga
    10561 ttaagttatg gtacactgaa ggtgtatata ggaggtttgt attttgaaaa taggttatgc
    10621 aagagtttca actggattac aaaatttaaa tttacaggaa gatcgattaa atacacatgg
    10681 ttgtgaaaag atatttaatg accatatgag tggttcaaaa agtaaaagac ctggtttaga
    10741 taaagcaatt gaatttgcga ggtcaggaga taccattgtt gtttggagac tagatagact
    10801 aggacgtaac atggaggatt taatcacatt agttaatgaa cttaacgaac gaggcgtgag
    10861 ttttcatagt ttagaagaaa atataacgat ggataaatca agttctacag gacaattatt
    10921 atttcattta ttcgcagcat ttgcagaatt tgaacgtaat ttaattttag aacgttcttc
    10981 agctggccga attgcggcac gtgcaagagg aagatatgga gggaggcctg aaaaattaaa
    11041 taaacaagat ttgaatttac ttaagacgct ttatgataat ggcacaccca ttaaaacaat
    11101 agcagaacaa tggaaagttt cacgtacaac tatttatcgt tacctcaata aattggagga
    11161 caaggaagat gaaaaacaag gagaagtatc taactaattt ttctgaagcc aaacgtaaag
    11221 aagctactca aaagtacaat ataataaaac cttttatctt gggaaatcaa tctttatcaa
    11281 gtatttctaa aaataaggac attgcattaa gtacacttta taggtggaat aaattatata
    11341 aggaagaagg gcttactggt ctaattcata atacaagagt tgataaaggt gatcataaat
    11401 tagaacaaaa cataattgac gagattaaac gcctttcact caagaataaa agaaatagta
    11461 ttgctacaat tcataggaaa atcgttaatt attgtataga aaataatttt gataaaccaa
    11521 gctacaaaca agtttatagt attattaaag caatgcctaa gtctgttatt gatttctctc
    11581 accaaggtga aaaatactat caaaataagt acgatttaat acaaataaga gaatcctcaa
    11641 gacccaatga aatatggcaa gccgaccata ctttgctaga tatttatata ttagatcaaa
    11701 caggtaatat taatagaccc tggctaacca ttattatgga tgactatagt cgcgcaattg
    11761 caggatactt tataagtttt gaagctccta atgctcaaaa tacagcatta acactacacc
    11821 aagcaatatg gaataagaat aataccaatt ggccagtatg tggtataccc gaaaaattct
    11881 acacagatca cgggagtgac tttacctcgc atcacatgga acaagtcgct attgatttga
    11941 aaattaactt gatgttttca aaagttggtg tccctcgtgg tcgcgggaaa atagaacgtt
    12001 tttttcagac agttaaccaa actttcttag agcaacttcc tggatatata aacaataatg
    12061 atactcctag cgatttaata gattttcaaa atttcgaaga aaaattacga tactttttaa
    12121 ttgaagatta taatcaaaaa gagcatagtg ctatccagag cactcctatc aatcggtgga
    12181 acagtaatca ttttttccct aatatgccaa gcagtttaga acaactt
//
