LOCUS       LR962290.1             13465 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  LR962290.1 Enterococcus faecalis isolate 28157_4#3 genome assembly,
            plasmid: 3.
ACCESSION   LR962290
VERSION     LR962290.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 20:44:42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 15470
            Orig. end    :: 28935
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13465
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:8465]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8465
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13465
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13465
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(105..1013)
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVRF
                     TFDQLKDLSNYKATANNRFIDDLEQTYKKILSLRSDRRSESGLTREFFVMFTEFKINGD
                     VEEPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSSYSKTMFRLLKQFRTKGFAYFS
                     KEDFHELLDIPKSYRESNIDQYVLKPIKQELTAIFKGLTIKKKYGKGRGKPVIGYQFTF
                     KPEIKKADDFNKHAPTKEEQKHALTQANEQTSYEETPNTLNERIKQKQRELELLQQIQE
                     LEKEKEGFCCKVLNLLSNKVE"
     CDS             complement(1928..2878)
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MSMLIARMQKINRGTLTIIENHNKRKFKSPLPKEIDTTLTCLNYD
                     LVLDSSISYRKAIIGYITQNKASDRALRKDAILVVEWLISSDSAFFISLSTEEIRRFFQ
                     TALEFFQKRYGINNVAYAQIHLDEPIPHMHLGVVPLREGRLTAKTVFTREELRNIQAEL
                     PDYLTHAGFDISRGQKKKARNPLKLEEEWEQLAQEKEALALERQTFQAYLQAIDSETKQ
                     FQEKLNSWVTFPRFSKTAKLSHEHYQELCDLLEQAKKAMNISKITKEVNKDLLLENKNL
                     KYNNQELINISKRVASENEQLREKIANLKRSSTSN"
     CDS             complement(3616..5013)
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MGYLRKDREFMDQKDWLNHSSIYSQQHHTFYRWVLYPVILFLCLT
                     GIFLAFAKKEVVIRTPAQLIAPKTEVLQVPVEAKIKTNTLKENQIVKKGETLVTFDTTS
                     LQNEKKRLEQENTLIEQQKNAAQTFINSLKNEQNLFETEDSFGYSNQLKSFFAEKEATI
                     YNSKQIEETIQKEQDIYNKSKELLEKQLTTRQKELQEWEQVRTAWINEQNIQGFSPEIT
                     SKYQLWQTQLSDVTEEQKKQTKSTILATIDEQIVQQKKEIEQLQAEKAKLVPPNTSKNE
                     INSQKEKEKQNKELSLATTKQKITELTDTQQKNELALKTINEQITQSTLKAPITGTVHL
                     NETIKNQLEIPKGTTLAEIYPKPKNSFLTFTALIPANESMRIKSGMTVHFKLDKKGVAT
                     KIIDGTLNEISENSTTTEQGTFYTIKGLLNSPEDFTSRYGLTGELSLVIGKKTYWQQLK
                     DILFNQE"
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 293.1; E-value:
                     7.4e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_20"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.7e-49, bitscore:
                     156.6, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 1.9e-262, bitscore:
                     864.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIYQQDEKDCGVACIAMILKHYKTEIPIHKLRELSGTDLTGT
                     SAFGLKKTFEKLGFHSPAIQADNDVWKEKDLPLPLIAHVLIDNKYMHYVVVYEIKGDTL
                     LIADPNPTKGKIKKTSEEFSKEWTGILLLPTPTKSYTPSKENVAGLSTFFPIIWSQKGI
                     VFHIILASLFITLFGIGSSYYFQGILDYFIPNQARSTLNIVSIGLIVVYLFRVLFEYSR
                     SYLLVILGQRMSIAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDANKIIDALASATLS
                     VFLDIGMVLLVGITLAIQNGTLFLITLASLPFYLVTILAFVKSYEKANQEEMAAGATLN
                     SSIIESLKGIETIKAYSGEEKVYERVDQEFIQLMKKSFQTATLDNIQQGIKHAIQLINS
                     ALILWLGSFYVMEGTISLGQLITYNALLVFFTDPLQNIINLQVKMQTAQVANKRLNEIF
                     AIEPEQAITSSEHEISNKIFQQEISLENVSFSYNMKAPILKNISCTIAPKSKVALVGVS
                     GSGKSTLAKLLVNFYAPSEGKICYGKINHLDIPFQQLREHITYVPQESFFFSGTIIENL
                     TFGLQKTPSFERIIEVCEAVQLTTFIEQQPLRYDMVLEEGGTNLSGGQRQRLAIARALL
                     KDADILILDEATSGLDTLLEHDILEYLLKLENKTVLFIAHHLPIAKACEQILVLHNGNL
                     VEQGTHEELRYNQGVYQQLWDI"
     CDS             7322..7522
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MKKYKVLTEKEIKQTVGGGWADFLGGLLGGLAPTRTAEQLNGSDY
                     ARFKARNCGPYGQGGTPNSCN"
     CDS             7544..7867
                     /locus_tag="ctg1_22"
                     /transl_table=11
                     /translation="MKTLYKKKIAEVWEISKTNKQPEWVKQAFAKNYLRWSSDNKLIIL
                     MSALEPSVTTNIKFGMVGSVGGGFAGYAMYSVGDIGDYLDVTNHKLVSKKSFNKHYLIQ
                     NQD"
     CDS             complement(7971..8132)
                     /locus_tag="ctg1_23"
                     /transl_table=11
                     /translation="MTEYAPNSKNPQKRLVYQTVVKQLKQGDTVAEIATENGLSRPTVY
                     KIKKANNL"
     CDS             8292..8465
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Antimicrobial17"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_24"
                     /sec_met_domain="Antimicrobial17 (E-value: 6.7e-42,
                     bitscore: 133.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYKVLTEKEMKRTIGGGSVFSKIGNTLGPAAYWLLKGLGNMSD
                     VNQADRINRKKH"
     CDS             8517..8669
                     /locus_tag="ctg1_25"
                     /transl_table=11
                     /translation="MKIIRDNELKKIIGGGPGKLLPWIQPVYDFVTGLTNGIRKEGNRN
                     KWKNV"
     CDS             8737..9060
                     /locus_tag="ctg1_26"
                     /transl_table=11
                     /translation="MNMLMNMLIFFNFVTFLYILIGVDINYKHAKNVYIFFFSVFILMI
                     CTIIVPMNLTWLTNLLGLLSIIAIICLYVILKKKSDFTKTNQGMFLLFFVTQSLYILLD
                     LFS"
     CDS             complement(10014..10514)
                     /locus_tag="ctg1_27"
                     /transl_table=11
                     /translation="MADKTIKELAEELGVSKTAINKKVSDENRKLWFAKIGNKFVINEV
                     GQKAIKSMFLAENENLNRQPVCEKTKTENHKNANQVSDLELLPFLKKQLDQKDIQLQEK
                     DTQIKQIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTAETSENEESQNDTPPTNKKKWW
                     QFW"
     CDS             complement(10524..11030)
                     /locus_tag="ctg1_28"
                     /transl_table=11
                     /translation="MFRLLKQYRTKGFAYFSKEDFHELLDIPKTYKQGNVDQKVLEPIR
                     QELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEEQKRALTQAN
                     KQTNYEEMPNTLNERIKQKKRELELLQQIQELEKEKEALEAQTESKLSEKEKKSLLSDL
                     DNLFN"
     CDS             11109..11798
                     /locus_tag="ctg1_29"
                     /transl_table=11
                     /translation="MTMNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIK
                     VLLGIPA"
     CDS             11871..13193
                     /locus_tag="ctg1_30"
                     /transl_table=11
                     /translation="MYTRQPGTTFKNTNGNIAVDHYNRYKEDVALMAEMGLKAYRFSIA
                     WTRIYPNGRNEVNEEGLKFYENLIDELIANNIQPIITLYHWDLPQHLQDLYGGWESREI
                     IHDFNEYCVTLFKRFGNKVKHWVSLNEQNIFVTLGYVTAMHPPAVKDQKRMLEANHIAN
                     LANATVIESFKKYVPDGMIGPSFAFGPVYPFSCDPKDVLSAENAEDLNCNWWLDVYCKG
                     KYPVFAFKYYERLGIAPTIEDGDLELLERVKPDFIGINYYQTSTVAFNPLDGVGQSEGI
                     NNTGKKGTAKESGLPGVYKNAKNPHLETTNWDWAIDPTGLRIGLRRLTSKYNLPILITE
                     NGLGEFDKLEEDDTVNDAHRIDYLSAHIKACKEAITDGVDLLGYCTWSFTDLLSWLNGY
                     QKRYGFVYVDRDENDQKDLRRIKKNSFYWYKNVIRTNGEEL"
ORIGIN
        1 aggttataac gaagatagta gcccacggct acaataatca catcctgctg aaattgcttt
       61 cctttaaaat gattcatcgt cattcctcct gctatctttt tctattattc taccttattt
      121 gatagtagat ttaaaacttt gcaacagaac ccttctttct ctttttctag ttcctgaatt
      181 tgttgtagta gttctaattc acgttgtttt tgttttatac gttcattaag agtattaggc
      241 gtttcttcat agcttgtttg ctcatttgct tgagttaaag catgtttttg ttcttctttg
      301 gttggcgcat gcttgttaaa atcgtccgct tttttaattt caggtttaaa tgtgaattgg
      361 taaccaataa ccggctttcc ccgacctttt ccgtatttct ttttgattgt tagccctttg
      421 aaaattgcgg ttagttcttg tttgataggt tttagaacat attgatcgat attactttct
      481 cgataacttt ttggaatatc taacaattca tgaaaatctt ctttggaaaa ataagcaaaa
      541 cctttagttc taaattgttt tagtagccta aacatggttt tagagtaact gctttgtagt
      601 tcgttgaatt gctgtaaaga gtagcgtacc cattcgtcta aattatttaa caagggtaga
      661 gctttttcgt aaattcgtat atctacataa ggctcttcta cgtcgccatt aattttaaat
      721 tccgtaaaca taacaaaaaa ttctctagtt agtccagatt cacttctacg atcagatcgc
      781 aaagagagga tttttttata agtttgttct aaatcgtcaa taaaacgatt attagctgtt
      841 gctttgtaat tacttaaatc tttcaattgg tcaaatgtaa agcgaacagt tttatcgcct
      901 ttttcacgca ttctggacac aatagagaag aatagattca tttcaactgg agtaaattta
      961 cgtaaaggaa tcgtatttaa ttcatgatga tattttacaa tttcatttga cataagagca
     1021 cctcacattt tataggcatg ttttaaaaag tataacatgc ctataaaatc atgtcaaaac
     1081 agacaattcc atgcctataa acagacaatt ccatgcctaa aagactctgt atcccttggg
     1141 agagtaagga cacagccgac ggtaaagagg tttaaaaaga gatttaaaaa gagggagggg
     1201 caaaatttcc cgcctaaaaa ccactccttt tttcctcaaa caggttcgcg aaatttttta
     1261 aactgcaaat cttgctccct acggtcgctt aaaaaggtgt gttcgcttcg ctctcacatt
     1321 gtactgcgca gtcgcctaaa ggctcctttg ctaaaaccgt tgttcaaaga ggtctttgtg
     1381 aggctctgag agcttgttta atccgtttta aaacagtttt agtataaagc ctttattctt
     1441 gtttataggt gccttacagg cggtcagggc aagccctaac aaccctaaag caattatgct
     1501 atactcaata cggacaactt gtccccaaag ggggtgctgt cttgttagaa caaattttta
     1561 cgttggttat cgcacctctt tttgtaggcc tagtcattga actagtttct cattggttag
     1621 acaagaaaga cgataactga aacaagttgt ccctaaccca caacgctaga cgtcgcaact
     1681 agcgaaaaaa agccagtcct attcgcagta ggactggctt ttgtgctgtc ttgtaacaaa
     1741 ttcttacgtt tcgcaagttc aatataacaa attagacgaa aaaaagcaaa atatacattt
     1801 cgactcaaat atatttaaac gcctctaatt ttcgatttaa gcaactttaa ctttaaatag
     1861 atatttttac ctaatccaat ttaaaacttc ttagaattgg aattagcgct gtttaaattg
     1921 attttaatta attgctggta gaagatcttt tcaaattggc aatcttctct cttagttgtt
     1981 cattttccga agctacccgt ttggaaatat tgattaattc ttgattgttg tactttaaat
     2041 ttttgttttc tagcaacaag tctttattga cttcttttgt tatttttgaa atattcatgg
     2101 ctttctttgc ttgttccaac aggtcacata gctcttgata gtgttcgtga gataacttgg
     2161 ctgttttaga aaatcgggga aaggttaccc agctgtttag tttttcttga aactgttttg
     2221 tctcagaatc aatggcttga agataggctt gaaacgtttg tcgttctaac gctaaagctt
     2281 ctttttcttg cgcgagttgt tcccattctt cctccagttt gagtgggttg cgcgcttttt
     2341 tcttttggcc acgtgaaata tcaaatccag catgtgttaa atagtcgggc aattcggctt
     2401 gaatgtttcg caattcttct cgggtaaaaa ccgtttttgc tgttaatcgt ccctcacgta
     2461 acgggacaac gcctaaatgc atatggggga tgggttcgtc taaatggatt tgcgcataag
     2521 caacgttgtt tatgccgtat cgtttttgaa aaaattctag tgctgtttgg aaaaatcggc
     2581 gaatttcttc tgtagataac gagataaaaa aagcagagtc actactaatc aaccattcca
     2641 ctacaagaat ggcgtctttt cttagcgcac gatcacttgc tttgttttga gtgatatatc
     2701 cgataattgc ttttctatag ctgatacttg aatctaacac gaggtcataa tttaagcagg
     2761 taagtgtggt atcgatttct ttgggcaggg gagatttgaa ctttcttttg ttgtgatttt
     2821 cgataatggt taacgttcct cggttaattt tttgcatacg cgcaataagc atagacatgg
     2881 gacaacctcc tttgtttttt tgagggaatt tttttcacaa gttttttgta agagcataag
     2941 gggaacctga tatcaaaatt gatataaacc gcagtgcggt ttggttctag catgatatca
     3001 ctttttttgt gaaaatcggc taaaaagcgg tttctgccgg ctggcgaaaa ccttgatatt
     3061 atgcggtttt tgaattttta acggtaaaaa ccgtcttttt accgactgaa aaactaattt
     3121 gtataaagta taattaatag actttatctt gtaaacaaac caattgtttt ttcgagtaaa
     3181 aacggaaatt ttagccaact ttctaggaaa atacccatta aatttttaag aaatacctca
     3241 cttaattgtt gagaaaaccg ttttttataa aataacaaaa acacctaaat ttttaggtgc
     3301 tataaatgtg ctaggttcat acgacatacc tgctataaat gtattatgac aatgtataaa
     3361 atcgcattaa atcaagctta aaacacatgt tagaaacctg ctatatacct actatgaatg
     3421 tgctatgagc gggtaaattt gtaccccacc ggaaagcctt gcactgcaag gcgggacacc
     3481 ttgtgtgact cccatttccc cttatgctct tcagaatatt cattgaaaaa atcgcacgat
     3541 gatattaaat aacaactatc cgagtgaagt cgaatagttg ttaaaatgta tttgtgataa
     3601 acaatttaaa tatatttatt cttgattgaa tagaatatct ttgagttgtt gccaataggt
     3661 tttcttgccg ataactagag ataattctcc cgtaagacca tatctactag taaagtcttc
     3721 aggtgaattt agtagtcctt ttattgtgta aaatgtccct tgttctgttg ttgtactatt
     3781 ttctgatatt tcatttaaag tgccgtcaat tatttttgta gctactccct ttttgtctaa
     3841 tttgaaatgc accgtcattc ctgacttaat tcgcatactt tcattagctg gaataagtgc
     3901 tgtaaacgta agaaatgagt ttttaggttt tggataaatt tctgctaacg tagtgccttt
     3961 tggaatttct aattggtttt tgatagtttc attcagatga accgttccag tgatgggggc
     4021 tttcaatgtg ctttgtgtaa tttgttcgtt gattgtttta agtgctaatt catttttttg
     4081 ttgtgtatcg gttaattctg ttattttttg tttggttgtt gctaaagata attctttgtt
     4141 ttgcttctct ttttcttttt gactatttat ttcgttttta gacgtatttg gagggaccaa
     4201 tttagccttt tctgcttgca attgctctat ttcttttttt tgttgaacaa tttgttcatc
     4261 gattgtagcc aagattgttg atttggtttg ttttttttgt tcttctgtta catcagacaa
     4321 ttgtgtttgc cataattgat atttggaagt gatttcaggt gaaaatcctt gtatgttttg
     4381 ttcgttaatc catgccgtac gtacttgttc ccattcttgt aattcttttt ggcgtgtagt
     4441 cagttgtttt tctagtagct cttttgattt attatagata tcttgttctt tttgtatagt
     4501 ttcttcaatc tgttttgaat tgtaaatagt cgcttctttt tcagcaaaga agcttttaag
     4561 ttgattacta taaccaaagg agtcttcagt ttcgaataaa ttttgttcat tttttaaact
     4621 attgataaag gtttgagcag cattcttttg ttgctcaata agtgtatttt cttgttctaa
     4681 tcgttttttt tcattttgta aagaggttgt atcaaatgtg actaatgttt cccctttttt
     4741 tactatttgg ttttctttta gagtattggt ttttatcttt gcttctaccg gtacttgtag
     4801 tacttctgtt ttgggtgcaa ttaattgagc aggcgttcga ataacaactt ctttttttgc
     4861 aaaagctaaa aaaatacctg ttaaacataa aaaaagaata actggataca agacccaacg
     4921 ataaaaggta tggtgttgtt gactataaat acttgaatga tttaaccaat ccttttggtc
     4981 cataaattct ctgtcctttc ttaaatatcc cataattgtt gatatacgcc ttgattgtaa
     5041 cgaagttctt catgtgtacc ttgttcaacc agatttccat tatgaaggac taaaatctgt
     5101 tcacacgctt tagcaatagg taaatgatgc gcaataaaaa gtactgtttt attttctaat
     5161 tttagtaaat attcaagaat atcatgttct aataaagtgt ctaaaccact tgttgcttcg
     5221 tctaaaatta gaatatcagc gtctttcaaa agcgcacgtg caatggctaa tcgttgacgt
     5281 tgcccgccag aaagattagt ccctccttct tctaatacca tatcgtagcg caatggctgt
     5341 tgttcaataa aagtggttag ttgcactgct tcgcacactt cgataattcg ttcaaaacta
     5401 ggtgttttct gtagtccaaa agtcaaattt tctataattg ttccactgaa gaaaaaggat
     5461 tcttgaggaa cataggtaat atgctcacgt aattgttgaa acggaatatc taagtgattg
     5521 atttttccat aacaaatttt tccttctgaa ggagcataaa aattgaccaa taatttagct
     5581 aaggttgatt ttcctgagcc acttacacca actaaagcca ctttgctttt tggtgcaatg
     5641 gtacaagaaa tattctttaa aatgggtgct ttcatgttgt aagaaaagga aacattttct
     5701 aaggatattt cttgctggaa gattttgttt gaaatttcat gttcggaaga agttattgct
     5761 tgttctggtt ctatagcgaa aatctcgttt aatcgtttgt ttgctacttg cgctgtttgc
     5821 attttaactt gcaaattaat gatattttgt aaaggatcag taaaaaagac caacaatgca
     5881 ttgtaagtaa ttaattgccc aagactaatg gttccttcca tcacataaaa tgatcctaac
     5941 cataaaatca gagcactatt aattaattga atagcgtgtt tgattccttg ttgtatgttg
     6001 tctaaagtag ccgtctgaaa agactttttc attaattgaa taaattcttg atcgactcgt
     6061 tcataaactt tttcttcccc actataggct ttaatggttt caatcccttt taaactttca
     6121 ataatacttg aatttaaggt agcacctgca gccatttctt cttgattggc tttttcataa
     6181 cttttaacaa aggctaaaat ggtaacaaga taaaacggga gcgaagctag agtaattaag
     6241 aataatgttc cgttttgaat agctaaagta attcctacta gtaataccat tccaatgtct
     6301 aaaaagacag ataaagtagc gctagctaag gcatcaataa ttttgtttgc atctaaaaaa
     6361 cgagagataa tctctcctga tttacgagta gcaaaaaaat tcataggtaa agtgaggaca
     6421 tgcttgaagt attgaagcat tatagctata ctcatgcgtt gtcctagaat aaccaagaga
     6481 taacttcggc tatattcaaa taaaacacgg aatagataaa caacaattaa tccgatagaa
     6541 acaatattta atgtggatcg tgcttgattt ggaataaaat aatctaaaat tccttgaaaa
     6601 taataagagc taccaatacc aaataaagta atgaaaagag aagctaaaat aatgtgaaaa
     6661 actattcctt tttgactcca aatgattggg aaaaaggtac tcaaaccagc tacattttct
     6721 ttactaggag tataagattt agttggagta ggtaacaata aaataccagt ccattctttg
     6781 gaaaattctt cacttgtttt ttttattttt ccttttgttg gatttggatc ggctattaat
     6841 aacgtatcgc cttttatttc atacacaaca acatagtgca tgtatttatt atcgattaac
     6901 acatgagcaa ttaaaggtaa tggtaaatct ttttctttcc atacgtcatt atctgcttga
     6961 atagcaggag aatgaaagcc cagtttttca aaagtttttt ttaatccaaa agcagaagtt
     7021 cctgttaaat ctgttcctga tagttcacgt aatttatgta taggaatttc agttttgtag
     7081 tgttttagaa tcatagcaat acaagcaaca ccacaatctt tttcgtcttg ttggtagata
     7141 atctttttca tattttcctc tcatttattt tgtatttatt ttcttattta gtttactata
     7201 ttgagataat tttgagaatt tttttcataa aaaatattga cagaatattt agactttggt
     7261 ttaataaaag tgagaagaaa acgttttctt aaaaagtttg aatagctagg agggactttt
     7321 tatgaaaaaa tataaagtgt taactgaaaa agaaataaaa caaactgttg gtgggggttg
     7381 ggctgatttt ttaggaggtc ttttaggtgg attagctcca acacgtactg ctgagcaatt
     7441 gaatggttca gattatgcaa gattcaaagc gcgtaactgt ggaccttatg gtcaaggcgg
     7501 gacccctaat tcatgtaatt gatagaaagt agatggttat tgtatgaaaa ctttatataa
     7561 gaaaaaaata gctgaagttt gggaaattag taagacgaac aaacagccag aatgggttaa
     7621 acaagctttt gctaaaaatt atttaagatg gtcttctgat aacaaattaa tcattttaat
     7681 gagtgcgtta gagccttcgg taactactaa tataaagttt ggaatggttg gttccgttgg
     7741 tggagggttt gctggatatg caatgtattc tgtaggtgat ataggtgatt atttagacgt
     7801 tactaatcac aaattagttt ctaaaaaaag ttttaacaaa cattatttaa tacaaaatca
     7861 agactagtct tattatataa gatttcatca ataataaacg tgtattacgg ggtacatgga
     7921 acatagaaac gaaaatgcac ggtagaaaag cgaataactg tagataaaat ctacaaatta
     7981 ttcgcttttt ttattttgta tacggttggc cgagaaagtc cattttctgt tgcgatttct
     8041 gctactgtat ctccttgttt taattgcttg actactgttt ggtaaacaag acgtttttga
     8101 gggtttttag aatttggcgc atactctgtc atttattttg tatttatttt tcttatttag
     8161 tttactatat tgagataatt ttgataactt ttttcataaa aaaatattga cagaatattt
     8221 agactttggt ttaataaaag tgaaaagaaa acgttttctt aaaaagtttg aatagctagg
     8281 agggactttt tatgaaaaaa tataaagtgt taactgaaaa agaaatgaaa cgaactattg
     8341 gtgggggatc ggtttttagt aagataggta atactttagg tccagcagct tattggcttt
     8401 taaaagggtt aggtaatatg agcgatgtaa atcaagctga cagaatcaat agaaaaaaac
     8461 attaatatct cagagagaag gtatatgtta tgaaaaatat taataattca aaaaatatga
     8521 aaataattag agataatgaa ttgaaaaaaa tcattggtgg tggtccagga aagttgttac
     8581 catggataca acctgtatat gattttgtta caggtcttac aaatgggatt agaaaagaag
     8641 gtaataggaa taaatggaag aatgtatagt aaatgtgtat aataaaagtg tattgaggta
     8701 gtccaataca cttttattat tttaaggaga taagctatga atatgttgat gaacatgcta
     8761 atttttttta attttgtaac ttttttgtat attttaatag gagtagatat taattataaa
     8821 catgctaaaa atgtgtatat tttctttttt agtgtattta ttctgatgat ttgtacaata
     8881 atagtgccga tgaatttaac atggttaact aatttattag gcttattaag tataattgct
     8941 attatttgtt tatatgtaat tttaaaaaag aaatccgatt tcacaaaaac aaaccaagga
     9001 atgtttttat tattttttgt tacacaaagt ttgtatatct tattggattt atttagttag
     9061 taaaaaatgg aacatgaaag tatttgttat gattattgaa aagttgtaaa ataatttttt
     9121 ggagaaatta ttatgaagaa gaaaagtaaa tttcgctttt tgattagttg tgttttaggc
     9181 atacttttat tgcttatagg tggaacgatc aatcaaaagt ctattgatga aaaatacaaa
     9241 ttgtgagtga taacttctgt ttttatgtta tttaaccgtc tagttaacat aatgaccact
     9301 aaacaaagta gcctctgtat caacgattac agaggctact ttgtgatttt ggattgatct
     9361 acctcttttg actttctaaa agcgcaaaaa gaccctcatt tttgtggttg gttttttgtg
     9421 aaaattgatt ggacaaagaa ggcattcttt gttattttat cgtaaaaaat aaggaacgaa
     9481 ttcgttctcg gagacacgaa ttcgttgaga tagtagtaaa taatttgtta ggaaattcta
     9541 tgtttaccaa cctaaattga gtataaaaat ttttttagga aaaatcaacc gttggtttct
     9601 aaaaaataat tgaaaaagca aaaaaagtta tgttaaaatt ttggtataaa ctcgttcatt
     9661 tttagcagaa agaactaggg aattgccatg cgcgaatcac gaatagaata aaacgaatgt
     9721 ttttaactcc tttagaccta gttctttcta caaaaaatga aacaaccact cacaaacgac
     9781 taaataattt attacacgaa aaagcactag gtcgaatgga ttaaaaacct agtgcttttt
     9841 tgtgcattta tttttatgcg ttttttgggt aaattaagta taacataagg tgcttttttt
     9901 ctgtcaagaa aaggaaaaag ttacctgtgg caagcatagc aaggtaggta caccttgcga
     9961 gaaaatctta cttgaataaa tagccgttta ggcttgtctt tttcttttta actctaccaa
    10021 aactgccacc actttttctt gttagttggt ggtgtatcgt tttgtgattc ttcgttttct
    10081 gacgtttctg cagtgtaagt taattgtagc tgttcttgta gcttctcgat ttgttggttt
    10141 gcttggagag tgagttgttg ttgctggtcg agtagttttt gtatttgttt tatttgagta
    10201 tctttttctt gtagctgtat atctttttga tccaactgtt tttttagaaa aggaaggagt
    10261 tccaaatcgg aaacttggtt ggcgttttta tggttttcgg ttttcgtttt ttcgcaaact
    10321 ggttggcgat ttaagttttc gttttcagcc aaaaacattg atttaatagc tttttgacca
    10381 acttcgttaa tcacaaactt gtttccgatt ttcgcaaacc aaagttttcg attttcatca
    10441 gaaacttttt tattaatagc tgttttacta actcctaatt cttcagcaag ttctttgatt
    10501 gttttatctg ccatacgtca ccttcagtta aacaaattat ctaaatcgga taataagctt
    10561 tttttctctt tttccgaaag ctttgattct gtttgtgctt caagagcttc tttctctttt
    10621 tctagttcct gaatttgttg tagtagttct aattcacgtt ttttttgttt tatacgttca
    10681 ttaagagtat taggcatttc ttcatagttt gtttgtttat ttgcttgagt taaagcacgt
    10741 ttttgttctt ctttggttgg tgcatgttta ttaaagtcgt ctgctttttt tatttctggt
    10801 ttaaatgtaa attgatagcc aatgacaggt tttccacgac cttttccata tttctttttg
    10861 attgttaaac ctttgaagat tgcggttaat tcttgacgga taggctcaag aaccttttga
    10921 tctacattac cttgcttgta ggttttaggt atatctagta attcatgaaa atcctcttta
    10981 gagaaatatg cgaaaccttt ggttctatat tgttttaaca agcgaaacat ggttttagag
    11041 ggttctgttg caaagtttta aatctactat caaataaggt agaataatag aaaaagatag
    11101 caggaggaat gacgatgaat cattttaaag gaaagcaatt tcagcaggat gtgattattg
    11161 tagccgtggg ctactatctt cgttataacc ttagctatcg tgaagttcaa gaaatcttat
    11221 atgatcgtgg cattaacgtt tctcatacga cgatttatcg ttgggtgcaa gaatatggca
    11281 aactactcta tcaaatttgg aaaaagaaaa ataaaaaatc cttttattca tggaaaatgg
    11341 atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc atcgatgcag
    11401 atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca gcctatgctt
    11461 ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca gataaagccc
    11521 cctctattac aagtgccttt aagaaactaa aagaatacgg cggcttttat caagggacag
    11581 aacatcgtac cattaaatac ctgaataatt tgattgaaca agaccatcgt ccagtaaaga
    11641 gacgcaataa attctatcga agtttacgca ctgcctctac cacgattaaa ggcatggaag
    11701 ccattcgagg attatataag aaaacccgaa aagaaggaac tctcttcggg ttttcggtct
    11761 gtactgaaat caaggtatta ttgggaatcc cagcttaaat catagatacc gtaagggatt
    11821 ttattcttta tttaaaactt tgcaacagaa ccggggaaag tgtatgggat gtgtacaccc
    11881 gccaaccggg gacaacattt aagaatacaa acgggaatat cgcggtcgac cattacaata
    11941 gatacaaaga agacgtagct ttaatggctg aaatgggatt gaaagcttat agattctcaa
    12001 ttgcatggac acgtatttat cccaatggaa gaaatgaagt aaatgaagaa ggcttaaaat
    12061 tttatgaaaa cttgatagat gaacttatcg cgaacaatat ccaaccaatc attacgttgt
    12121 accattggga tttacctcaa catcttcaag atttgtacgg cggatgggaa tcaagagaaa
    12181 tcattcatga ttttaatgaa tactgtgtaa cgttattcaa gagatttggg aataaagtta
    12241 agcactgggt atcattgaat gaacaaaata tatttgtaac actaggttac gtaaccgcta
    12301 tgcacccgcc agctgttaaa gatcaaaaga gaatgcttga ggcgaatcat atagcgaact
    12361 tagctaatgc taccgtaatt gaatccttca aaaaatatgt tccagacggt atgattggac
    12421 caagctttgc atttggacca gtttatccat tcagttgcga tccaaaagat gttttatccg
    12481 cagaaaatgc agaggattta aattgcaatt ggtggctcga tgtttattgc aaaggtaaat
    12541 atccagtgtt cgcttttaaa tattacgaaa gacttggaat cgcacccact attgaagatg
    12601 gagatcttga attgttggaa agagtaaaac cagattttat cggaataaat tattaccaaa
    12661 caagcacagt tgcattcaat ccgcttgatg gagtagggca atcggaaggt atcaataaca
    12721 caggtaaaaa aggcaccgct aaagaaagcg gattacccgg agtttataaa aatgcaaaaa
    12781 atccacatct ggaaacaaca aattgggact gggcaattga tcctactggt ttaagaattg
    12841 gactaagaag attgaccagc aaatataatc ttccaatact tattacagaa aacgggcttg
    12901 gagaattcga caagcttgaa gaagacgaca ctgtcaatga tgctcacaga atcgattact
    12961 tgagcgcaca tatcaaggct tgtaaagaag caataacaga tggtgttgat cttctaggct
    13021 actgcacgtg gtcatttaca gatttgttaa gctggttgaa tggttatcaa aaacgctatg
    13081 gatttgtgta tgtggacaga gatgaaaatg atcaaaaaga tttgagaaga atcaaaaaga
    13141 acagcttcta ttggtacaaa aatgttattc gcaccaatgg agaagagtta taagaatcgt
    13201 tcacaatcaa tgaatatgaa aaaacaagga gagatagacc atgaaaaaaa ttttactagt
    13261 atgttcagca ggaatgtcca caagtttgct tgtgaccaaa atgagaaact ccgcaaagga
    13321 aaaaggaatt gaagtagaaa tagatgctct tccagttgca gaggcaagta cggccgttga
    13381 taatgtcgat atcgttcttt taggaccaca agtgcgtttc cagaaagaga ccgttgaaaa
    13441 acttgtaaaa ggcagaattc ccgta
//
