LOCUS       CP157138.1             14652 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CP157138.1 Escherichia coli strain UTAK-16 plasmid pUTAK-16-4-pCol,
            complete sequence.
ACCESSION   CP157138
VERSION     CP157138.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 21:34:42
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14652
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14652
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2471:11894]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2472..11894
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14652
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14652
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(3..413)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MIVKFHARGKGGGSGPVDYLLGRERNREGARILRGDPEEVRELID
                     ATPFAKKYTSGVLSFAEQTLPPGERERVMESFERVLMPGFEKNQYSILWVEHQDKGRLE
                     LNFVIPNMELVSGKRLQPYYDRADRPRINAWQT"
     CDS             complement(403..750)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MIPVKRERMLTIRVTDEEHARLLARCEGKQLASWMRKVCLGAPPS
                     KTSGLPTLAPPLLRQFASVGNNLNQIARKINSGHWSGHDRVHVVAALMAIGRELSELRD
                     EVRKQGERDDS"
     CDS             793..984
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MTKQEKTALNMARFIRSQTLILLEKLNELDADDQADICEALHDHA
                     DELYRSCLARFGDDGENL"
     CDS             complement(1996..2142)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MKKKIGVSIILVLVVLCLTACQNNYVRDVQGGTIAPSSSSKLTGV
                     AIQ"
     CDS             complement(2212..2475)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MNKMAIIDLAKSFLASKITAMEFSERICVERRKLYGVKNLSQDVL
                     NCGEELFIAAERFEPDSDRADYEFDDNGLRIEVQSILEKFKL"
     CDS             complement(2472..4565)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6"
                     /sec_met_domain="Cloacin (E-value: 7.2e-95, bitscore:
                     306.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSM
                     PPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAART
                     VLENGLRSGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPVSQLPAAGN
                     NVPVKYRLTDLMQNGTQYIAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNL
                     PDLVLSVGQMNTPVLSNPEIQEEGVIAETGNYVEAGYTMSSNNHDVIVRFPDGSGVSPL
                     YISTVEILDRNGLSQRQEAENKAKDDFRVKKEEAVARAEAEKAKAELFSKAGVKQPPVY
                     TQEMVERANSVMNEQGTLVLNNTASSVQLAMTGTGVWTAAGDIAGNISKFFSNALEKVT
                     IPEVGPLLMRISLGALWFHSEDAGAGSDIVPGRDMEAMFSLNAQMLAGQGMVIEPGATS
                     VNLPVRGQLINSNGQLALDLLKTGNDSIPAAVPVLNAVRDTATGLDKITLPAVVGAPSR
                     TILVNPAPQPSAPTDTGNHQPVPVTPVHTGTEVKPVEMPVTTITPVSDAGGLRDFIYWR
                     PDATGTGVEAVYVMLNDPLDSGRFSRKQLDKKYKHAGDFGISDTKKNRETLTKFRDAIE
                     EHLSDKDTVEKGTYRREKGSKVYFNPNTNNVVILKSNGEFLSGWKINPDADNGRIYLET
                     GEL"
     CDS             4841..5260
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MAWHTLQDALKMTGRSRSQFYRDMRAGLVSYRTGQDGRREFETSE
                     LIRAYGELKQDETAERHSAGQAENPHDQQTERILRELNELKQCLTLMLEDKQAQDTERR
                     RQEAEREQLHKEIEQLRQALEQEKKRGFWARLFSR"
     CDS             5346..5603
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MRRSGGTLYLIALLTAATVLTACTPKGSVEQHTRHYAYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVRA"
     CDS             complement(5895..6116)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MVPERVKNASGRDSGVSFLLLCFASLPDRAHSSASSRDVCVCHQL
                     KRWKKNSVMRFTQAKPALFTWLNSYAYG"
     CDS             complement(6144..7742)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MIVKFHARGKGGGSGPVDYLLGRERNREGARILRGDPEEVRELID
                     ATPFAKKYTSGVLSFAEQTLPPGERERVMESFERVLMPGFEKNQYSILWVEHQDKGRLE
                     LNFVIPNMELVSGKRLQPYYDRADRPRINAWQTLVNHHYGLHDPNAPENRRTLVTPNNL
                     PKAKQEAAEAITRGLEALYHAGALKTRQDVTEALTAAGFEVVRTTRSSISIADPEGGRN
                     LRLKGALYEQSFTNGDRLREETERACRLYREHAEQRVQEARSVCRQGTELKRAENQRRY
                     QRTHSSAERTTGDAEQCRERAVQRHRERTGPAAGRAALEADQRADTVPVADGALRHGRD
                     FSGVMGADSVAGKPDCGEHPGYQGPGRDAGETPGKNMGCDVSRGQEREISGIAVRGEGG
                     KQLDGGEEERSKTGQGVSEYDRAGNALTERLRAIAAGLYAAAERLGERLHGFAAYVRAD
                     TTGERATEGTVRRLESAGAEISRAGGPLESVIYHEQQIRDEQERLARLERERARSWHEE
                     QEREVRVWRGPSMGM"
     CDS             complement(7732..8079)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MIPVKRERMLTIRVTDEEHARLLARCEGKQLASWMRKVCLGAPPS
                     KTSGLPTLAPPLLRQFASVGNNLNQIARKINSGHWSGHDRVHVVAALMAIGRELSELRD
                     EVRKQGERDDS"
     CDS             8122..8313
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MTKQEKTALNMARFIRSQTLILLEKLNELDADDQADICEALHDHA
                     DELYRSCLARFGDDGENL"
     CDS             complement(9325..9471)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MKKKIGVSIILVLVVLCLTACQNNYVRDVQGGTIAPSSSSKLTGV
                     AIQ"
     CDS             complement(9541..9804)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MNKMAIIDLAKSFLASKITAMEFSERICVERRKLYGVKNLSQDVL
                     NCGEELFIAAERFEPDSDRADYEFDDNGLRIEVQSILEKFKL"
     CDS             complement(9801..11894)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_15"
                     /sec_met_domain="Cloacin (E-value: 7.2e-95, bitscore:
                     306.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSM
                     PPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAART
                     VLENGLRSGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPVSQLPAAGN
                     NVPVKYRLTDLMQNGTQYIAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNL
                     PDLVLSVGQMNTPVLSNPEIQEEGVIAETGNYVEAGYTMSSNNHDVIVRFPDGSGVSPL
                     YISTVEILDRNGLSQRQEAENKAKDDFRVKKEEAVARAEAEKAKAELFSKAGVKQPPVY
                     TQEMVERANSVMNEQGTLVLNNTASSVQLAMTGTGVWTAAGDIAGNISKFFSNALEKVT
                     IPEVGPLLMRISLGALWFHSEDAGAGSDIVPGRDMEAMFSLNAQMLAGQGMVIEPGATS
                     VNLPVRGQLINSNGQLALDLLKTGNDSIPAAVPVLNAVRDTATGLDKITLPAVVGAPSR
                     TILVNPAPQPSAPTDTGNHQPVPVTPVHTGTEVKPVEMPVTTITPVSDAGGLRDFIYWR
                     PDATGTGVEAVYVMLNDPLDSGRFSRKQLDKKYKHAGDFGISDTKKNRETLTKFRDAIE
                     EHLSDKDTVEKGTYRREKGSKVYFNPNTNNVVILKSNGEFLSGWKINPDADNGRIYLET
                     GEL"
     CDS             12170..12589
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MAWHTLQDALKMTGRSRSQFYRDMRAGLVSYRTGQDGRREFETSE
                     LIRAYGELKQDETAERHSAGQAENPHDQQTERILRELNELKQCLTLMLEDKQAQDTERR
                     RQEAEREQLHKEIEQLRQALEQEKKRGFWARLFSR"
     CDS             12673..13092
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MRRSGGTLYLIALLTAATVLTACTPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLRGTTQ
                     FAGTDYRSKDLTPKKSRLLAETISAVYLDGYEGRQ"
     CDS             complement(13218..13439)
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MVPERVKNASGRDSGVSFLLLCFASLPDRAHSSASSRDVCVCHQL
                     KRWKKNSVMRFTQAKPALFTWLNSYAYG"
     CDS             complement(13467..14651)
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MNHHYGLHDPNAPENRRTLVTPNNLPKAKQEAAEAITRGLEALYH
                     AGALKTRQDVTEALTAAGFEVVRTTRSSISIADPEGGRNLRLKGALYEQSFTNGDRLRE
                     ETERACRLYREHAEQRVQEARSVCRQGTELKRAENQRRYQRTHSSAERTTGDAEQCRER
                     AVQRHRERTGPAAGRAALEADQRADTVPVADGALRHGRDFSGVMGADSVAGKPDCGEHP
                     GYQGPGRDAGETPGKNMGCDVSRGQEREISGIAVRGEGGKQLDGGEEERSKTGQGVSEY
                     DRAGNALTERLRAIAAGLYAAAERLGERLHGFAAYVRADTTGERATEGTVRRLESAGAE
                     ISRAGGPLESVIYHEQQIRDEQERLARLERERARSWHEEQEREVRVWRGPSMGM"
ORIGIN
        1 agtgtctgcc aggcattgat tcgcggacgg tccgcacggt cgtaataggg ctggagccgt
       61 tttccgctca ccagctccat attcgggatg acaaaattca gctcaagacg ccccttgtcc
      121 tggtgctcca cccacaggat gctgtactga tttttttcaa aaccgggcat cagtacccgc
      181 tcaaagctct ccatcaccct ttcacgctct cccggtggca gtgtctgctc tgcaaaagac
      241 agaacccccg aggtgtattt tttcgcaaac ggcgtggcat cgatgagttc ccgcacctct
      301 tcgggatcac cccgcagaat tctcgcccct tcccggttac gctcccggcc cagcaggtaa
      361 tcaaccggac cactgccacc gccttttccc ctggcatgaa acttaactat catcccgttc
      421 tccctgttta cggacctcat ccctcagctc actcagttca cgtccgatgg ccatcagtgc
      481 agccaccaca tgaacccggt catgccccga ccagtgtccg ctgtttatct tccgggctat
      541 ctgattcagg ttattgccga ccgaagcgaa ctggcgcaac agcggcggtg ccagtgtcgg
      601 aagacctgac gttttcgatg gcggtgcacc caggcagacc ttacgcatcc atgacgcaag
      661 ttgttttccc tcacaacgtg ccagcagccg cgcatgttcc tcatccgtga cccgtatcgt
      721 gagcatcctt tcgcgtttca ccggtatcat taaaaacctc cgacagactc cccacacatg
      781 gagaacagaa ctgtgactaa acaggaaaaa acagccctta acatggcccg ctttatcaga
      841 agccagacgc tgatcctgct ggaaaaactg aatgaactgg acgccgacga ccaggcagac
      901 atctgcgaag cccttcacga ccacgccgac gagctttacc gcagctgcct cgcacgcttc
      961 ggggatgacg gtgaaaacct ctgacacatg cagctcccgg agacggtcac agcttgcctg
     1021 tgagcggatg ccgggagcag acaagcccgt cagggcgcgt cagcgggttt tagcgggtgt
     1081 cggggcgcag ccatgaccca gtcacgtagc gatagcggag tgtatactgg cttaatcgtg
     1141 tggcatcagt gaggattgta tgaaaagtgc accatgtacg gtgtgaaatg ccgcacagat
     1201 gcgtaaggag aacatgcaga tgccgatgct cttccgcttc ctcgctcact gactcgctgt
     1261 gctcggtcgt tcggctgcgg cgagcggtgt ctgctcacac aaaagcggca atactgttat
     1321 ccacagaatc aggggataac gccggaaaga acatgtgagc aacaagacaa agccggggaa
     1381 aaggccgcgc cggtggcgct ttttccatag gctccgcccc cctgacgagc atcacaaaaa
     1441 ccgacgctca agtcagaggt ggcgaaaccc gacaggactt aaagatacca ggcgtttccc
     1501 cccggaagct ccctcgtgcg ctctcctgtt ccgaccctgc cgattaccgg atacctgtcc
     1561 gcctttctcc cttcgggaag cgtggcgctt tctcatagct cacgctgttg gtatctcagt
     1621 tcggtgtagg tcgttcgctc caagctgggc tgtgtgcacg aaccccccgt tcagcccgac
     1681 cgctgcgcct tatccggtaa ctatcgtctt gagtccaacc cggtaagaca cgactttacg
     1741 ccactggcag cagccattgg taactgaaaa gtggatttag atacgcagaa ctcttgaagt
     1801 tgaagcctta tcgcggctac actgaaagga cagcatttgg tatctgtgct ccactaaagc
     1861 cagttacctt cggaaaaaga gttggtagct cttgttccgg caaacaaacc accgttggta
     1921 gcggtggttt ttttgtttgc aagcagcaga ttacgcgcag aaaaaaagga tctcaagaag
     1981 atcctttaat ctttttcact gaatcgctac cccggttagt ttcgaggatg atgatggagc
     2041 aatcgttcct ccctgaacat cccttacata gttattttga caagcagtca gacacaaaac
     2101 aacaagaacg agaataatcg atacccctat cttttttttc ataacatctc cttgtcatga
     2161 gtgagtatct gacatttata attaaattcc agatattaaa atcactcata tttataattt
     2221 aaatttttcc aggatagatt ggacttcaat cctaagtcca ttatcatcga attcataatc
     2281 agccctatca gaatcaggct cgaaacgctc agcagctata aacaactcct ccccacaatt
     2341 caatacatcc tgagacaaat tcttaacacc atacaatttt ctccgctcaa cacaaatccg
     2401 ctctgaaaac tccattgctg ttatttttga agctaaaaat gacttcgcca aatcgattat
     2461 cgccatcttg ttcatagttc acctgtttct aaataaattc gcccattatc cgcatctgga
     2521 tttattttcc acccagataa gaactcacca tttgatttta gtatcaccac attatttgta
     2581 ttaggattaa aataaacttt tgatcctttt tctcgtcggt atgttccttt ctctactgta
     2641 tccttatcgg ataaatgttc ctcaatagca tccctgaatt tagtaagagt ttcacgattc
     2701 tttttagtat cactaatacc aaaatcacca gcatgtttat attttttatc aagctgtttg
     2761 cgtgaaaacc gccctgaatc cagaggatca ttaagcatca catagacagc ttcaacacca
     2821 gtcccggtag catcaggacg ccagtaaata aaatctcgaa gtccaccggc atcagagact
     2881 ggagtaatcg tcgttaccgg catttcaacc ggttttacct ccgtacctgt atgcactggg
     2941 gtaaccggaa cgggttgatg atttcctgta tctgttggtg ccgaaggttg tggggccgga
     3001 tttaccagaa tcgtcctgga aggtgcaccg actactgctg gcagcgtaat tttatccagt
     3061 cctgtagctg tatcacgaac agcattaaga acaggaaccg cagcagggat actatcattc
     3121 cctgtcttca gtaaatccag agcaagttgt ccgttactgt ttatcaattg tccacgaaca
     3181 ggcagattaa cactcgtagc accaggttca atgaccatgc cctgtcctgc caacatctga
     3241 gcattcagcg agaacatagc ctccatatct cgccccggca cgatatcact tcctgctccg
     3301 gcgtcttctg aatggaacca cagagcgcca agagaaatcc gcataagcag gggacccact
     3361 tcgggtatgg ttactttctc cagagcatta ctgaaaaact tgcttatgtt gcctgcaata
     3421 tcaccagcag ccgtccagac accagttccg gtcatcgcca gttgtacaga actggcagtg
     3481 ttattcagaa caagagttcc ctgctcattc attactgaat tagccctttc caccatttcc
     3541 tgtgtatata caggaggctg tttcacacct gctttactaa ataactcggc ttttgctttt
     3601 tcagcttcgg cccgggctac cgcttcttct ttcttgactc tgaaatcatc ctttgcttta
     3661 ttttctgctt cctgacgctg actcagacca ttacggtcaa gaatctccac agttgaaata
     3721 tataacggag aaacaccgct gccgtcagga aaacgaacaa tgacatcatg attattactg
     3781 gacatcgtat aacctgcctc aacataatta cctgtctcag caataacgcc ctcttcctga
     3841 atttcgggat tagacagaac cggagtattc atctgcccca cacttaatac caggtccggt
     3901 agatttggtg atacaggggc actgtaaaca tctttaatat ttgttcccgg acggctccgg
     3961 tccggaaccg gaacggcatc aactaccggc actgtcatcg gaatacctcc gataatagca
     4021 atatattgcg taccgttctg cataaggtcc gtcagacgat atttcaccgg tacattatta
     4081 cccgctgctg gtaactggct gacaggaata tccgttacct gctccagttg ctgtgtaacc
     4141 ataagacgaa taattttttg ctcatttccg gaagcaggct ccagacgggc aaaagaaaca
     4201 gcagccgggc gtgatggttc tggcaaacca ctacgtaaac cattctcaag aactgttcgt
     4261 gcagcagaaa ctttctcgtt tccccaggga ctatgcacac tgacagacca tcccgaccag
     4321 tccccctctt caagttcctt atcaaggata atccggcgaa taattcctgg aaaaagaaca
     4381 ctttgtacaa gtgcgatacc ttgtggactg taatctcccc atcccggagg catggatgga
     4441 gcgagacctg atgaaccacc gggtttcaca tcaccgcccg gaattcgtcc agttgacggc
     4501 cacacaacca ttgtgtcccc gtaatcaata ccttctgtcg ggacactacc ttcattatca
     4561 ctcatagaaa acctctttga cattaaaaac aaatagttaa aagacgcata ctgtatatac
     4621 aaccactggt tttatataca gtttaaaatt acgccgctgc gttttccctg tcaaccctgt
     4681 ggattttcgt ttttgtgaaa acgatcaaaa aaacagccac ccacaccacg tgctattccc
     4741 acccgatgcc acaaaaacca gcacaaacat taccgttctc cggccccagt atgttttact
     4801 gaaaccatga tatgagacac caataggaca ctgtcacttc atggcatggc acacactcca
     4861 ggacgcactg aaaatgacag gcagatcgcg ttcacagttt taccgtgata tgcgcgcagg
     4921 ccttgtcagt taccgtaccg gccaggacgg acgacgggag tttgaaacca gtgaactgat
     4981 ccgggcatac ggcgaattaa agcaggatga gacagcagaa aggcacagtg cgggacaggc
     5041 agaaaatcca catgatcagc agacagaacg cattctccgg gagctgaatg agctgaaaca
     5101 atgcctgaca ctgatgcttg aggacaaaca ggcacaggat acggaacgcc ggcgccagga
     5161 agccgaacgg gaacagctac ataaagagat agagcagctc aggcaggcac tggagcagga
     5221 aaaaaaacgg ggattctggg ccagactgtt cagccggtga gcatcgagct gcaagtgatg
     5281 atgaggtcgt cagcggttaa atatacagtc actgagtaca aagatttaaa ggtaaggaga
     5341 cactcatgag acgttccggc ggcacactgt atcttatcgc cctgctgaca gcggcaacgg
     5401 tcctgacagc ctgcacgcca aagggcagtg tggaacaaca tacccggcat tacgcttatg
     5461 catcagacga tggttttgat cctaactttt ccacccagaa ggccgacaca acacgaatga
     5521 tggtgccttt tttccggcag ttctgggata tgggagcaaa ggataaagcg acaggaaaat
     5581 cacggagtga tgtgcgggcg tgacgcatat cagcagtttc acagccagga atttttaaac
     5641 tcactccggg gcacaactca atttgcgggt actgattacc gcagcaaaga ccttaccccg
     5701 aaaaaatcca ggctgctggc tgagacgatt tctgcggttt atctcgatgg ctacgaggga
     5761 agacagtaag tggatttacc ataatccctt aattgtacgc accgctgaaa tgcgttcagc
     5821 gcgatcacgg ctgctgacag gtaaaaatgg caacaaacca cccgaaaagc tgccgcgatc
     5881 gcacctgata aattttaacc gtatgcatag ctattcagcc atgtgaataa cgctggtttt
     5941 gcctgcgtaa acctcatgac actgtttttt ttccatcttt tcagttgatg acatacgcag
     6001 acatcgcggg atgaggctga ggaatgagcg cgatctggca aagaggcaaa acacagcaac
     6061 aaaaacgaca cgccagaatc gcgcccggat gcatttttaa cgcgttccgg taccatctgg
     6121 caacctcccg gaacaactca ccgtcacatc cccattgacg ggccacgcca tacccgtact
     6181 tcccgttcct gctcttcatg ccaggaccgc gcacgctccc gttccaggcg tgccagcctt
     6241 tcctgttcat cccttatctg ctgttcgtga taaataaccg actcaagcgg tccacctgcc
     6301 cggctaatct ctgcacctgc tgactcaagt cgtcgcactg ttccctcagt tgcccgttct
     6361 cctgtcgtgt cagctcgaac atatgctgca aatccgtgaa ggcgctctcc cagtctttca
     6421 gccgctgcgt atagtcctgc tgcaattgct ctaaggcgtt cagtaagtgc atttccagct
     6481 ctgtcatact cacttactcc ctgaccagtc ttactgcgtt cttcttctcc accgtccagt
     6541 tgttttcccc cttcaccccg gacggcaata ccagaaattt cccgttcctg ccctcgtgat
     6601 acgtcacacc ccatgttttt tcccggagtt tcgccagcgt ctcttcctgg tccctgatag
     6661 ccaggatgtt cgccgcaatc cggctttcct gccactgaat cagcccccat gacgccagaa
     6721 aaatcccgcc cgtgacgcaa agcgccgtca gcgacgggta cagtatccgc cctttgatca
     6781 gcttccagag cagctcttcc tgccgccggg ccagttcgtt ctctgtggcg ctgaactgcg
     6841 cgttcacggc actgttcagc gtctccagtt gttctttcag cgctgctgtg tgtgcgctga
     6901 tagcgtctct gattttctgc ccgtttaagt tcagttccct gtctacagac gcttcgagct
     6961 tcctgaactc gctgttcagc atgttctctg tagagacggc acgctctttc agtttcttct
     7021 cgaagtctgt ccccatttgt aaaagattgc tcatacagcg cccctttcag cctgagatta
     7081 cgcccgccct ccgggtcggc gatactgata ctgctcctgg ttgtcctcac cacctcaaaa
     7141 cctgccgctg taagcgcctc agtgacatcc tgacgcgttt ttagcgctcc ggcatgataa
     7201 agagcctcca gccccctcgt aatcgcttct gcggcctcct gtttcgcttt cggcagatta
     7261 ttcggggtga caagtgtccg cctgttctcc ggtgcgttcg ggtcgtgcag cccgtaatga
     7321 tgattcacca gtgtctgcca ggcattgatt cgcggacggt ccgcacggtc gtaatagggc
     7381 tggagccgtt ttccgctcac cagctccata ttcgggatga caaaattcag ctcaagacgc
     7441 cccttgtcct ggtgctccac ccacaggatg ctgtactgat ttttttcaaa accgggcatc
     7501 agtacccgct caaagctctc catcaccctt tcacgctctc ccggtggcag tgtctgctct
     7561 gcaaaagaca gaacccccga ggtgtatttt ttcgcaaacg gcgtggcatc gatgagttcc
     7621 cgcacctctt cgggatcacc ccgcagaatt ctcgcccctt cccggttacg ctcccggccc
     7681 agcaggtaat caaccggacc actgccaccg ccttttcccc tggcatgaaa cttaactatc
     7741 atcccgttct ccctgtttac ggacctcatc cctcagctca ctcagttcac gtccgatggc
     7801 catcagtgca gccaccacat gaacccggtc atgccccgac cagtgtccgc tgtttatctt
     7861 ccgggctatc tgattcaggt tattgccgac cgaagcgaac tggcgcaaca gcggcggtgc
     7921 cagtgtcgga agacctgacg ttttcgatgg cggtgcaccc aggcagacct tacgcatcca
     7981 tgacgcaagt tgttttccct cacaacgtgc cagcagccgc gcatgttcct catccgtgac
     8041 ccgtatcgtg agcatccttt cgcgtttcac cggtatcatt aaaaacctcc gacagactcc
     8101 ccacacatgg agaacagaac tgtgactaaa caggaaaaaa cagcccttaa catggcccgc
     8161 tttatcagaa gccagacgct gatcctgctg gaaaaactga atgaactgga cgccgacgac
     8221 caggcagaca tctgcgaagc ccttcacgac cacgccgacg agctttaccg cagctgcctc
     8281 gcacgcttcg gggatgacgg tgaaaacctc tgacacatgc agctcccgga gacggtcaca
     8341 gcttgcctgt gagcggatgc cgggagcaga caagcccgtc agggcgcgtc agcgggtttt
     8401 agcgggtgtc ggggcgcagc catgacccag tcacgtagcg atagcggagt gtatactggc
     8461 ttaatcgtgt ggcatcagtg aggattgtat gaaaagtgca ccatgtacgg tgtgaaatgc
     8521 cgcacagatg cgtaaggaga acatgcagat gccgatgctc ttccgcttcc tcgctcactg
     8581 actcgctgtg ctcggtcgtt cggctgcggc gagcggtgtc tgctcacaca aaagcggcaa
     8641 tactgttatc cacagaatca ggggataacg ccggaaagaa catgtgagca acaagacaaa
     8701 gccggggaaa aggccgcgcc ggtggcgctt tttccatagg ctccgccccc ctgacgagca
     8761 tcacaaaaac cgacgctcaa gtcagaggtg gcgaaacccg acaggactta aagataccag
     8821 gcgtttcccc ccggaagctc cctcgtgcgc tctcctgttc cgaccctgcc gattaccgga
     8881 tacctgtccg cctttctccc ttcgggaagc gtggcgcttt ctcatagctc acgctgttgg
     8941 tatctcagtt cggtgtaggt cgttcgctcc aagctgggct gtgtgcacga accccccgtt
     9001 cagcccgacc gctgcgcctt atccggtaac tatcgtcttg agtccaaccc ggtaagacac
     9061 gactttacgc cactggcagc agccattggt aactgaaaag tggatttaga tacgcagaac
     9121 tcttgaagtt gaagccttat cgcggctaca ctgaaaggac agcatttggt atctgtgctc
     9181 cactaaagcc agttaccttc ggaaaaagag ttggtagctc ttgttccggc aaacaaacca
     9241 ccgttggtag cggtggtttt tttgtttgca agcagcagat tacgcgcaga aaaaaaggat
     9301 ctcaagaaga tcctttaatc tttttcactg aatcgctacc ccggttagtt tcgaggatga
     9361 tgatggagca atcgttcctc cctgaacatc ccttacatag ttattttgac aagcagtcag
     9421 acacaaaaca acaagaacga gaataatcga tacccctatc ttttttttca taacatctcc
     9481 ttgtcatgag tgagtatctg acatttataa ttaaattcca gatattaaaa tcactcatat
     9541 ttataattta aatttttcca ggatagattg gacttcaatc ctaagtccat tatcatcgaa
     9601 ttcataatca gccctatcag aatcaggctc gaaacgctca gcagctataa acaactcctc
     9661 cccacaattc aatacatcct gagacaaatt cttaacacca tacaattttc tccgctcaac
     9721 acaaatccgc tctgaaaact ccattgctgt tatttttgaa gctaaaaatg acttcgccaa
     9781 atcgattatc gccatcttgt tcatagttca cctgtttcta aataaattcg cccattatcc
     9841 gcatctggat ttattttcca cccagataag aactcaccat ttgattttag tatcaccaca
     9901 ttatttgtat taggattaaa ataaactttt gatccttttt ctcgtcggta tgttcctttc
     9961 tctactgtat ccttatcgga taaatgttcc tcaatagcat ccctgaattt agtaagagtt
    10021 tcacgattct ttttagtatc actaatacca aaatcaccag catgtttata ttttttatca
    10081 agctgtttgc gtgaaaaccg ccctgaatcc agaggatcat taagcatcac atagacagct
    10141 tcaacaccag tcccggtagc atcaggacgc cagtaaataa aatctcgaag tccaccggca
    10201 tcagagactg gagtaatcgt cgttaccggc atttcaaccg gttttacctc cgtacctgta
    10261 tgcactgggg taaccggaac gggttgatga tttcctgtat ctgttggtgc cgaaggttgt
    10321 ggggccggat ttaccagaat cgtcctggaa ggtgcaccga ctactgctgg cagcgtaatt
    10381 ttatccagtc ctgtagctgt atcacgaaca gcattaagaa caggaaccgc agcagggata
    10441 ctatcattcc ctgtcttcag taaatccaga gcaagttgtc cgttactgtt tatcaattgt
    10501 ccacgaacag gcagattaac actcgtagca ccaggttcaa tgaccatgcc ctgtcctgcc
    10561 aacatctgag cattcagcga gaacatagcc tccatatctc gccccggcac gatatcactt
    10621 cctgctccgg cgtcttctga atggaaccac agagcgccaa gagaaatccg cataagcagg
    10681 ggacccactt cgggtatggt tactttctcc agagcattac tgaaaaactt gcttatgttg
    10741 cctgcaatat caccagcagc cgtccagaca ccagttccgg tcatcgccag ttgtacagaa
    10801 ctggcagtgt tattcagaac aagagttccc tgctcattca ttactgaatt agccctttcc
    10861 accatttcct gtgtatatac aggaggctgt ttcacacctg ctttactaaa taactcggct
    10921 tttgcttttt cagcttcggc ccgggctacc gcttcttctt tcttgactct gaaatcatcc
    10981 tttgctttat tttctgcttc ctgacgctga ctcagaccat tacggtcaag aatctccaca
    11041 gttgaaatat ataacggaga aacaccgctg ccgtcaggaa aacgaacaat gacatcatga
    11101 ttattactgg acatcgtata acctgcctca acataattac ctgtctcagc aataacgccc
    11161 tcttcctgaa tttcgggatt agacagaacc ggagtattca tctgccccac acttaatacc
    11221 aggtccggta gatttggtga tacaggggca ctgtaaacat ctttaatatt tgttcccgga
    11281 cggctccggt ccggaaccgg aacggcatca actaccggca ctgtcatcgg aatacctccg
    11341 ataatagcaa tatattgcgt accgttctgc ataaggtccg tcagacgata tttcaccggt
    11401 acattattac ccgctgctgg taactggctg acaggaatat ccgttacctg ctccagttgc
    11461 tgtgtaacca taagacgaat aattttttgc tcatttccgg aagcaggctc cagacgggca
    11521 aaagaaacag cagccgggcg tgatggttct ggcaaaccac tacgtaaacc attctcaaga
    11581 actgttcgtg cagcagaaac tttctcgttt ccccagggac tatgcacact gacagaccat
    11641 cccgaccagt ccccctcttc aagttcctta tcaaggataa tccggcgaat aattcctgga
    11701 aaaagaacac tttgtacaag tgcgatacct tgtggactgt aatctcccca tcccggaggc
    11761 atggatggag cgagacctga tgaaccaccg ggtttcacat caccgcccgg aattcgtcca
    11821 gttgacggcc acacaaccat tgtgtccccg taatcaatac cttctgtcgg gacactacct
    11881 tcattatcac tcatagaaaa cctctttgac attaaaaaca aatagttaaa agacgcatac
    11941 tgtatataca accactggtt ttatatacag tttaaaatta cgccgctgcg ttttccctgt
    12001 caaccctgtg gattttcgtt tttgtgaaaa cgatcaaaaa aacagccacc cacaccacgt
    12061 gctattccca cccgatgcca caaaaaccag cacaaacatt accgttctcc ggccccagta
    12121 tgttttactg aaaccatgat atgagacacc aataggacac tgtcacttca tggcatggca
    12181 cacactccag gacgcactga aaatgacagg cagatcgcgt tcacagtttt accgtgatat
    12241 gcgcgcaggc cttgtcagtt accgtaccgg ccaggacgga cgacgggagt ttgaaaccag
    12301 tgaactgatc cgggcatacg gcgaattaaa gcaggatgag acagcagaaa ggcacagtgc
    12361 gggacaggca gaaaatccac atgatcagca gacagaacgc attctccggg agctgaatga
    12421 gctgaaacaa tgcctgacac tgatgcttga ggacaaacag gcacaggata cggaacgccg
    12481 gcgccaggaa gccgaacggg aacagctaca taaagagata gagcagctca ggcaggcact
    12541 ggagcaggaa aaaaaacggg gattctgggc cagactgttc agccggtgag catcggctgc
    12601 aagtgatgat aagatagtca gcggttaaat ataagtcact gagtacaaag atttaaaggt
    12661 aaggagacac tcatgagacg ttccggcggc acactgtatc ttatcgccct gctgacagcg
    12721 gcaacggtcc tgacagcctg cacgccaaag ggcagtgtgg aacaacatac ccggcattac
    12781 gtttatgcat cagacgatgg ttttgatcct aacttttcca cccagaaggc cgacacaaca
    12841 cgaatgatgg tgcctttttt ccggcagttc tgggatatgg gagcaaagga taaagcgaca
    12901 ggaaaatcac ggagtgatgt gcagcaacgc attcagcagt ttcacagcca ggaattttta
    12961 aactcactcc ggggcacaac tcaatttgcg ggtactgatt accgcagcaa agaccttacc
    13021 ccgaaaaaat ccaggctgct ggctgagacg atttctgcgg tttatctcga tggctacgag
    13081 ggaagacagt aagtggattt accataatcc cttaattgta cgcaccgctg aaatgcgttc
    13141 agcgcgatca cggctgctga caggtaaaaa tggcaacaaa ccacccgaaa agctgccgcg
    13201 atcgcacctg ataaatttta accgtatgca tagctattca gccatgtgaa taacgctggt
    13261 tttgcctgcg taaacctcat gacactgttt tttttccatc ttttcagttg atgacatacg
    13321 cagacatcgc gggatgaggc tgaggaatga gcgcgatctg gcaaagaggc aaaacacagc
    13381 aacaaaaacg acacgccaga atcgcgcccg gatgcatttt taacgcgttc cggtaccatc
    13441 tggcaacctc ccggaacaac tcaccgtcac atccccattg acgggccacg ccatacccgt
    13501 acttcccgtt cctgctcttc atgccaggac cgcgcacgct cccgttccag gcgtgccagc
    13561 ctttcctgtt catcccttat ctgctgttcg tgataaataa ccgactcaag cggtccacct
    13621 gcccggctaa tctctgcacc tgctgactca agtcgtcgca ctgttccctc agttgcccgt
    13681 tctcctgtcg tgtcagctcg aacatatgct gcaaatccgt gaaggcgctc tcccagtctt
    13741 tcagccgctg cgtatagtcc tgctgcaatt gctctaaggc gttcagtaag tgcatttcca
    13801 gctctgtcat actcacttac tccctgacca gtcttactgc gttcttcttc tccaccgtcc
    13861 agttgttttc ccccttcacc ccggacggca ataccagaaa tttcccgttc ctgccctcgt
    13921 gatacgtcac accccatgtt ttttcccgga gtttcgccag cgtctcttcc tggtccctga
    13981 tagccaggat gttcgccgca atccggcttt cctgccactg aatcagcccc catgacgcca
    14041 gaaaaatccc gcccgtgacg caaagcgccg tcagcgacgg gtacagtatc cgccctttga
    14101 tcagcttcca gagcagctct tcctgccgcc gggccagttc gttctctgtg gcgctgaact
    14161 gcgcgttcac ggcactgttc agcgtctcca gttgttcttt cagcgctgct gtgtgtgcgc
    14221 tgatagcgtc tctgattttc tgcccgttta agttcagttc cctgtctaca gacgcttcga
    14281 gcttcctgaa ctcgctgttc agcatgttct ctgtagagac ggcacgctct ttcagtttct
    14341 tctcgaagtc tgtccccatt tgtaaaagat tgctcataca gcgccccttt cagcctgaga
    14401 ttacgcccgc cctccgggtc ggcgatactg atactgctcc tggttgtcct caccacctca
    14461 aaacctgccg ctgtaagcgc ctcagtgaca tcctgacgcg tttttagcgc tccggcatga
    14521 taaagagcct ccagccccct cgtaatcgct tctgcggcct cctgtttcgc tttcggcaga
    14581 ttattcgggg tgacaagtgt ccgcctgttc tccggtgcgt tcgggtcgtg cagcccgtaa
    14641 tgatgattca cc
//
