LOCUS       CP128735.1             15270 bp    DNA              UNK 01-JAN-1980
DEFINITION  CP128735.1 Klebsiella pneumoniae strain CRE-234 plasmid pCRE-234_6,
            complete sequence.
ACCESSION   CP128735
VERSION     CP128735.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:55:14
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             3..221
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MWDAQNVTDRVLAAADKLADFPRLYEVDSRYGEDVRRISLMGQHV
                     LYDVDDQTRKVRVLAVVGQRQNPHIVL"
     CDS             complement(283..660)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
     CDS             729..908
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
     CDS             complement(936..1466)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
     protocluster    1150..12835
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6149:7835]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6150..7835
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1150..12835
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1150..12835
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1473..2204)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
     CDS             complement(2204..4168)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
     CDS             complement(4880..5008)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MEKRHLRGLAVLPHMLVPCLFTESVGNFACVRSARRSLTAGA"
     CDS             complement(5883..6140)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
     CDS             complement(6150..7835)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_9"
                     /sec_met_domain="Cloacin (E-value: 2.3e-113, bitscore:
                     367.1, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
     CDS             complement(8571..9275)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
     CDS             complement(9287..9544)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDID
                     LLVTVTVRLDETTRRALINDLLETALLQIVGGDKLIIPFC"
     CDS             complement(9626..10231)
                     /gene_functions="resistance (resist) AAC6-Ib (Score: 433;
                     E-value: 5.6e-133)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     62.9; E-value: 6.5e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRS
                     HIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGW
                     WEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAI
                     RCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"
     CDS             complement(10414..10971)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             11133..11789
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKAL"
     CDS             11786..14137
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MTISGPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGM
                     TSVFNIARMSPQKRMAVLVAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRS
                     LKDLDKSALALASACSYLLKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNF
                     HDEMVEQYGRVRRFLPHLLNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEII
                     SQSWKRLVINKEKHITRRGYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQ
                     ANRIKVYRSLGHPTDPQEAIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISP
                     LASLDEPDSLKRLSKMISDLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVS
                     ISAVLMAEACNIGLEPLIRSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPL
                     AQIWGGGEVASADGMRFVTPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPG
                     TLRDSIFVLEGLLEQETGLNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFW
                     RMDHDADYGVLNDIARGQSDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPS
                     GLTQAIIEVGRINKTLYLLNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKR
                     YTDGQEDQLGALGLVTNAVVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINM
                     LGHYSFTLAELVTKGHLRPLKEASEAENVA"
     CDS             14214..14633
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
     CDS             14939..15202
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
     CDS             15192..15269
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENS"
ORIGIN
        1 ccctgtggga tgcgcagaac gttaccgacc gggttctcgc tgcggcggac aaactggccg
       61 acttcccgcg actctatgaa gtggactcac gctatggcga ggacgttcgc cggatcagtc
      121 tgatgggaca gcatgtcctc tatgatgttg atgaccagac cagaaaagtc cgggttctgg
      181 ccgtggtcgg ccagcgccag aatccccata ttgttctcta ataaccggtg acggggacgc
      241 aattcattgc gtggccgtcg ccggttggac aagcacagcg cgtcagcgtt ttccccacgg
      301 ccaccaccgg cgcggtgttc cggccggggt ctctgctgtc tccggtttgt gttccagcag
      361 tctcatggac tgcatttcct gccgtagccc ggccacctcc tccctgagtg cttttatctc
      421 cgcgatcaac gcgtcggagg ccattttttc agtctcaccc gacagtctca actcgtcccg
      481 ctcgtgagtc tcatcctgtc ttaactcacc gtacacccgg ataagctcgc tggtatccac
      541 cacccggccg ccatcagctt ccgtacggta tgatacgcgg cctttcgcca tatcccgata
      601 cagggaactt cgggctttac ccgtcagttc cgtcgcctgt ctcaccgtca cccacgccat
      661 tgtctcaccc cgctattttt gagacagtat acctgacagg cgcacaccat gcccggaagg
      721 aaagaatcat gacaaaacag gaaaaaacag ccctcaatat ggctaaattt attaaggagc
      781 agtcgctgct attgctcgat aaactgaatg agctggatat ggataccccg gccgacatgt
      841 gcgagcggct acacgaggat gcggaaacac tctggcaggt gatgcgggat aagctcgggg
      901 aggaataaca gcaccggcat ggccggtgct ggcatttatt ttttgccgaa cggccaccac
      961 cggcgggcag gtttgtcctc cggcagttca ggtaccggca cgttaaaata gcggctgtta
     1021 tattcccgca tcagctccgc tttcagcttc tcgttcaccg cgctttcccc gtgccgctca
     1081 ctcaccacgt caatcatcgc gttaatctgc tccggtgagc acttcccggc atcaaccacc
     1141 tgcacaccgt tctcgatggc gaaccgctcc accttgcgat agaggtaatc acacagcttc
     1201 attcctgtgg gtttgttccg ttcccattgc ggatttttac cagtgaaaaa gtacgtggct
     1261 ttttcgtcgc tgttgagccg ctcgtcatac atcccgatgg atttcatcat cgccagatgc
     1321 tgggcccggt cgacaaaaca gaaaacatac gccccggtct gccaggcgag caccaccata
     1381 tcttccagat gctcgctggt cggcatgatg cagcgctcgc cgttccggtc ctccgcgtct
     1441 tcaataaata ccatgtacag cgccataatc cctcactccg ttgtcataaa tttaaagcac
     1501 gcaaacaacc gttcacgatc cagctctgcc gttttgcggg cctcgccggt ctgtgggttc
     1561 acgatttcat ccaccgacag gattgcccgc tgcaccctga cctgcgtcgc ccggtccggg
     1621 cagatgtacc agatttcatc gatgccgtta gctttgcggt tgaacagata cccggacacc
     1681 acttcctgat accggcgacg gctcttgacg gtgcgctcca cctcaaacgc caccgtttta
     1741 ccgtccagct ccgccagggc gtccggcact ttcatgcctt taagactcag acggtgcaga
     1801 atgcgccagc cggtggcccc tctggcttcc atatcaaggc gcagggattg cacggccagc
     1861 cggtgcggca gatgtgctgc cgacaccctt gacggctgaa acggaataac atccgccagc
     1921 ggttcgtcct cgtcgaacga gaacgccacg ccatgcggcg tcagccccca cacgctgacc
     1981 tgacggccgt ccaccggata tttggtccgg accagcagcc ctttcgccac caggctgtcg
     2041 aggaagcggt agaccggctg caccgccgca atccccagcc gccgcgcaac cagctccgcc
     2101 gtggaacaca gctcttcccg caaccagcgc agggtcagcc gggttttctc cgcgttccgc
     2161 gcctgtcgtt tcgcgtggct gacgttgtac agctccagcg ccatcagtaa atccccgcaa
     2221 aatcatcatc cgctttcggc ccgccgccgt cggccggggg ccggaactcc gccaggggat
     2281 cggttttcgc cagcaccggg aaacgctgca acgggatttc ccggcgctca acccgcagcg
     2341 gactgctgaa cgccatccgg gccacaccca gcccggtcat gaccgcgaac ccgtccggca
     2401 ggtgttgcag ggtgttcacg tcaaacagcg gccgcgcctc cttctggatg aagctgtccc
     2461 cgctgatatg ctccacgttc cccgcctccc ggctggcacg gcggcgctcc acgtccaccc
     2521 tgatttcccc ggtctgcccc gccgcccact gcgcggactc caggctggcc gcccggtaaa
     2581 accagcggat cggcgtgtta tccagtaccg tggttttcac aaattcagcg ggcagatcct
     2641 gcccgcactg cccgaaatcg cccagcgact ggtgcgcgag caacagattg cagtcccggc
     2701 tgcgcagcgt ccccagtgcg ttcagtacat acttcgacag cagatattta atttcatcga
     2761 gcatcacgct gacgtgtggc cactcccgga actcgtcccg cgcaatgatg atttgcgcgc
     2821 agcgggcaaa cagcattttt tgcacacgga tcaccgcctc gtcgtccatc gagccgataa
     2881 cgtacaggca gccgccgccg ttgataatcc ccgccacatc gatgccactg tccgtctgca
     2941 ggacgctcag gtcagcgacg ttttccagcc tagtgatcaa ccccttcacg tcctttttca
     3001 gggcctccgg cagcgcgtac gccgccgcca gcacctgctg aatgtttgcc ccctgcggaa
     3061 actgctccgc aatcagcttc gccgctttct gctcgctgat gcggtagtgg tccgccacgt
     3121 cgccggtctc gcccaggtta agcccggcaa tcagcaggtt tttcagcgcg tactggtcga
     3181 gatcgcggaa cagattcagc tgcgccggtt tccccggccg cagatccagc agggtgaagt
     3241 ccggacagtg cgcccggaag acgtgcggcg cccatgcgtc ccctttgggg tcgaagtaca
     3301 ccaccgcgtc cccgaaatcg cgtacgcagc gaatgagcgc gttggtggcc atcacgctct
     3361 tgccgctccc gggcaggccg aggatctgaa tgttggtctt gcgccaggta tcacgcggaa
     3421 ccagcaccgg cttgccctgc tcatccttac ccagaaacac cgcctgctcc tgccgggcct
     3481 gctccgagga aaaatcggcc agcgcattaa ccggtaccgg ctccccgaaa tgcaggtggc
     3541 gcacgtcggt catctctcct gtccgctggc tgctgcgccg gctctcctga ttcagtttcg
     3601 cgttcaccgc ctcgtcagca gccgcaaaat gaccgtcaag cagcaggaac gccagcagcc
     3661 gcgccaacac aatcccgaca gccagcccgc ccgcgcacca ggcaatcccg aacaggttag
     3721 ccggctgcag caggtaataa tctgcgtttg cgtagaggtc cggacgcagg acggtttctc
     3781 cccagctctc gataaacacg gcgacaacca gcccccccag aagggccaga ccggccgcgc
     3841 cggtcagcca gtacgcgtag ttccagacat gtcgacgtgc cctgaccatc cgcccgggcg
     3901 aatccagcga ggccagcacc gaaaatggcg ctggccgttt attatcgcgc ttatagcgat
     3961 cggcatactc ccgtcgctcc ttatgactca gccccacaaa acgcatccgt ccggcccaaa
     4021 gttcagccag accgaaaaac aggccgataa ctaggaaagc cccggccaga ccgtaatact
     4081 cctggtacag ccagctgacc cacggataaa tctgccgggc cagctccgga atgtgccact
     4141 tccaggcaag cgaatccgta ttaaacatgt tctctctcct tcagacgatg gtttgccggc
     4201 gtgatgtgca gcccccgctg cacaagccgc ggacatgccc caaggcatgg cggcggcggt
     4261 cacgtccgtg gtgattgcgt tcagctttca ccacggaggc cagcctcttt ccgccccatg
     4321 cggaaaaggc gcagccccgg aggaacaacg agcacgcccc agcgtgtgag aggaaaaggc
     4381 ggcaccccag tgcggtcttt tccggtgttc cggcccccgt cagagttcgc catagcgagc
     4441 ggctgaccac ccgcaaaatc aggagcagct ttgctgcttc gccaggtgcg tccagcaccg
     4501 tggatttttg tgggtggtca ggcgtgagcc tgacgggggc cgggtgaatt tctggcgtgg
     4561 ccggcgtcca gccggacgga gccagaaaga gggggagaga ccgtgcgtcg gtggcgtcca
     4621 gccagcgtaa gcaggggata tccccctgag gtcagccacg ccctcgcggg gatgacctgt
     4681 atttctccgt aaggagaaaa aagcaacaga gataggttaa cgtaaaatgt tcagcgaaaa
     4741 accgatatga ttcacctatc ctggtaattt attatcaggg aatataaaga cttaatcagg
     4801 ggacaatatg ccacatcagc gcgtccggtg tccgtcttgt aggtgccggg gaaattgcgc
     4861 ctcctcgctc actcggtcgc tacgctccgg ccgtgagact gcggcgggcg ctgcggacac
     4921 atgcaaagtt acccacagat tccgtgaata agcaggggac taacatgtga ggcaaaacgg
     4981 caaggccacg caggtggcgt ttttccatag gctccgccct cctgactgag ttcacataaa
     5041 cagacgcttt ttcggtgcat ctgtgggagc cggtggctca accatgaatc agtcaggagt
     5101 ggcgaaaccc gacaggactt aaagatcatc accgtttccg atgaatcgct ccctcttgcg
     5161 ctctcctgtt ccaaccctgc cgtttcccgg atacctgttc cgcctttctc ccttgcggga
     5221 agtgtggcgc tttctcatag ctcacactct ggtatctcgg ctcggtgtag gtcgttcgct
     5281 ccaagctggg ctgtaagcaa gaaccccccg ttcagcccga ctgctgcgcc ttatccggta
     5341 actgttcact tgagtccaac ccggaaaagc acgcaaaacg ccactggcag cagccattgg
     5401 taactgggag ttcgcagagg atttgtttag ctaaacacgc ggttgctctt gaagtgtgcg
     5461 ccaaagtccg gctacactgg aaggacagat ttggttgctg tgctctgcga aagccagtta
     5521 ccacggttaa gcagttcccc aactgactta accttcgatc aaaccacctc cccaggtggt
     5581 tttttcgttt acagggcaaa agattacgcg cagaaaaaaa ggatctcaag aagatccttt
     5641 gatcttttct actgaaccgc gatccccgtc agttcagagg aggacgatgg tgccaccgtt
     5701 ccaccctgaa catcccggat atagtttgcc tgacatgcga ccagaagaaa gcctgaaaaa
     5761 atcaatataa aaagaaaaac aacctttacc tttttcatat accttccctg tatttaaaaa
     5821 ccccggtatt catccctgaa caccggaagt ctgtatttca aatcatcctt gataactttt
     5881 gcttaccagt taccatcccg gtaaacaaag gatacaaagt aatcaaattt actaatatcg
     5941 attacatttt taaagtgtgg ctgtaatatc gaaacccatg atttttcaac atcaaaccaa
     6001 ccattattaa tattatcctt taaaggcatc cccagacttt caatgacaga accatcatca
     6061 ccgaagtctt ttgagtattc accaccttta aactcttcgg ttttcttatc aaaccaatga
     6121 atatgtaatt taagccccat atttacctct taaagatatt ttttaatgtt tcgttttgga
     6181 tccggccctt taacctgctt acccgttttt ggatcgaatg ccccgaggtg ttcgccatca
     6241 ctggcgcggt acccttcaag ctcaccgtgc tgggaatccc attcataaat tttacgcttt
     6301 ttatcaccat accatcgggc ccgcttacca ccaccacctt gtttaggggt tttaggttta
     6361 ccctctttca actctcccaa ccccttaata tcttcagtct tgggatcagg aaaataatca
     6421 tggccgtaat ctttagttcc cttacgaggt tttttctttt cctcatttaa tttattttct
     6481 gcatccttcg cttttttctc cttttgtttc cggctctcca tcgccccgga aagcgcagcc
     6541 ttatccctgg ataaggattc attcatttcg tttaaagatg tctgggcagc ttttaatttc
     6601 tcattctgat tctgaatatc cttatcaaga tagcgaacct gatcctgcca cccggagcca
     6661 tattcatgag gcgggttata agtcacaaaa tcatctttat ttgcctctgc ctcttttacc
     6721 tttttatcgg cttcctgaac agcagccctt gcaccgggga tcgccttctc tgtcgatgca
     6781 atgcgactgt ttaaggtcgc aatattttta tcttcagcat ccagctcagc tttcgcttta
     6841 tcatactctc ttttcagccc ctcttccggg tgagcagcgt cccatgcctg ctggcgacgc
     6901 ttttcttcct ccagacgctg ttttacctgt gccggagtaa gaacatccgt caccgacaca
     6961 tagaccggtt tctgtccgct ctctttcggg aaacgaataa cggcttcacg ggagttacca
     7021 ccggccgtaa aaccagccgg acgtgaatca cctttttcag caataatgcc ttttggcggg
     7081 gctttcgcgg ccggaacacc tttaggtacg ctcacctgca gagacgggag acccggaatc
     7141 gacacactga atacccccgg acgttttgtc ggtttcgcat ccaccacagg aacactcatt
     7201 ggccggccgg tgacaaccgc aatatgctgc cgctcgtcct tcacaatatc cgccacacgt
     7261 ttagtgacgc tgaccgtcgc ctggtccagc ggcagggagc tgaccggcgt ctccgttacc
     7321 gtgtctgccg gcaatgacgt cacgattttt gacatcattt tcggatcatc ttttgctatc
     7381 tcagaaggca gcactccgta aatcgcaatc ccccacagac caaacttaaa cggacctttc
     7441 agggcagcca gcacatcagc aacagcggcc gacaacgcat cgccggaaac ggataaagcc
     7501 agtccttcag cccccggagt ggccaaggca ggcagaccga aggccatcgc ggtggccgaa
     7561 gactgtccgc caccagagct cccgctatga ttgccgctgt taccgccatt accaccgggt
     7621 ttactcccgc cgttaccaaa ctcccccggg ttatagttat gaatatcccc gttaggtgta
     7681 tgcgtcgtac cccagcccgg cccgctgttt ggatccgtac caccacctga tgaagggcca
     7741 cctttacctg atgtaccgtt cacattccca ctggcctgac caccattgtg tcccagacct
     7801 gaattacccg gacctcgtcc gtctccgcca ctcatatact tttcctcttt gacttttaaa
     7861 acaataaact aaaataaaat actgtacata taaccactgg ttttatatac agtataaaaa
     7921 ttacgctgcc ttgtttttca tgtcaagtct gtaaatttgc gtttttgtga aaatgatcaa
     7981 aaaaacagcc actcacacca tgcgcaatcc cctccagatg caacaaaaac cagcacaaac
     8041 ggcgccgttc tccggcctca gtatgtttta ctgaaatcat tatatgagat accagaaagc
     8101 cccctccggg acaggaaaag aaacgggggt ctggttcggg ttgttcggtc actgaacacg
     8161 gtcagaaact gatgataaga tagcctgcgg atatataagg ggtctgacgc tcagtggaac
     8221 gaaaactcac gttaagggat tttggtcatg agattatcaa aaaggatctt cacctagatc
     8281 cttttaaatt aaaaatgaag ttttaaatca atctaaagta tatatgagta aacttggtct
     8341 gacagttacc aatgcttaat cagtgaggca cctatctcag cgatctgtct atttcgttca
     8401 tccatagttg cctgactccc cgtcgtgtag ataactacga tacgggaggg cttaccatct
     8461 ggccccagtg ctgcaatgat accgcgagac ccacgctcac cggctccaga tttatcaggg
     8521 cactgttgca aagttagcga tgaggcagcc ttttgtctta ttcaaaggcc ttacatttca
     8581 aaaactctgc ttaccaggcg catttcgccc aggggatcac cataataaaa tgctgaggcc
     8641 tggcctttgc gtagtgcacg catcacctca atacctttga tggtggcgta agccgtcttc
     8701 atggatttaa atcccagcgt ggcgccgatt atccgtttca gtttgccatg atcgcattca
     8761 atcacgttgt tccggtactt aatctgtcgg tgttcaacgt cagacgggca ccggccttcg
     8821 cgtttgagca gagcaagcgc gcgaccatag gcgggcgctt tatccgtgtt gatgaatcgc
     8881 gggatctgcc acttcttcac gttgttgagg attttaccca gaaaccggta tgcagctttg
     8941 ctgttacgac gggaggagag ataaaaatcg acagtgcggc cccggctgtc gacggcccgg
     9001 tacagatacg cccagcggcc attgaccttc acgtaggttt catccatgtg ccacgggcaa
     9061 agatcggaag ggttacgcca gtaccagcgc agccgttttt ccatttcagg cgcataacgc
     9121 tgaacccagc ggtaaatcgt ggagtgatcg acattcactc cgcgttcagc cagcatctcc
     9181 tgcagctcac ggtaactgat gccgtatttg cagtaccagc gtacggccca cagaatgatg
     9241 tcacgctgaa aatgccggcc tttgaatggg ttcatgtgca gctccatcag caaaagggga
     9301 tgataagttt atcaccaccg actatttgca acagtgccgt ttccaaaagg tcgttgatca
     9361 aagctcgccg cgttgtttca tcaagcctta cggtcaccgt aaccagcaaa tcaatatcac
     9421 tgtgtggctt caggccgcca tccactgcgg agccgtacaa atgtacggcc agcaacgtcg
     9481 gttcgagatg gcgctcgatg acgccaacta cctctgatag ttgagtcgat acttcggcga
     9541 tcaccgcttc cctcatgatg tttaacgttt gacatgaggg gcggccaagg gcgccagccc
     9601 ttggacgtcc ccctcgatgg aagggttagg caacactgcg tgttcgctcg aatgcctggc
     9661 gtgtttgaac catgtacacg gctggaccat ctggggtggt tacggtacct tgcctctcaa
     9721 accccgcttt ctcgtagcat cggatcgctc gcaagttgct cggcgacggg tccgtttgga
     9781 tcttggtgac ctcgggatca ttgaacagca actcaaccag agctcgaacc agcttggttc
     9841 ccaagccttt gcccagttgt gatgcattcg ccagtaactg gtctattccg cgtactcctg
     9901 gatcggtttc ttcttcccac catccgtccc cgcttccaag agcaacgtac gactgggcat
     9961 acccaatcgg ctctccattc agcattgcaa tgtatggagt gacggactct tgcgctaaaa
    10021 cgcttggcaa gtactgttcc tgtacgtcag caagtgtcgg gcgtgcttct tctccgcccc
    10081 accactcgac gatatgagat cgatttagcc actcatagag catcgcaagg tcatgctcag
    10141 tcatgaggcg cagtgtgacg gaatcgttgc tgttggtcac gatgctgtac tttgtgatgc
    10201 ctaactttgt ttggaaatgt tgaatactca tactcttcct ttttcaatat tattgaagca
    10261 tttatcaggg ttattgtctc atgagcggat acatatttga atgtatttag aaaaataaac
    10321 aaataggggt tccgcgcact tttccccgaa aagtgccacc tgacgtctaa gaaaccatta
    10381 ttatcatgac attaacctat aaaaataggc gtatcacgag gccctttcgt cttcaagaat
    10441 tttataaacc gtggagcggg caatactgag ctgatgagca atttccgttg caccagtgcc
    10501 cttctgatga agcgtcagca cgacgttcct gtccacggta cgcctgcggc caaatttgat
    10561 tcctttcagc tttgcttcct gtcggccctc attcgtgcgc tctaggatcc tccggcgttc
    10621 agcctgtgcc acagccgaca ggatggtgac caccatttgc cccatatcac cgtcggtact
    10681 gatcccgtcg tcaataaacc gaaccgctac accctgagca tcaaactctt ttatcagttg
    10741 gatcatgtcg gcggtgtcgc ggccaagacg gtcgagcttc ttcaccagaa tgacatcacc
    10801 ttcctccacc ttcatcctca gcaaatccag cccttcccga tctgttgaac tgccggatgc
    10861 cttgtcggta aagatgcggt tagcttttac ccctgcatct ttgagcgctc tgatctgaat
    10921 atcgagggac tgctggctgg ttgagacccg cgcataacca aaaattcgca taaaaatgta
    10981 ccttaaatcg aatatcagac acgatgtgtc tattatgcca aaatgacgat ttaatggaca
    11041 ctcaaacgaa gccgttttac tatgtctgat aatttataat atttcgaacg gttgcagttg
    11101 tgttaaaaaa gccgtcaggc agggaggccg atatgcccgt tgattttttg accactgagc
    11161 aggttgagag ttatggcagg ttcactggcg aacccgatga acttcagctg gcgcgttatt
    11221 ttcatcttga tgaagcggat aaagaattta tcgggaaaag ccggggtgat cacaatcgac
    11281 ttggtattgc cctgcaaatc gggtgtgtgc gttttctggg cacttttctt actgacatga
    11341 atcatattcc ttccggcgtc cggcatttta ccgccagaca gctcgggatt cgtgatatca
    11401 ccgttcttgc agaatacggt cagagggaaa atacccgccg tgagcatgca gcgctgatac
    11461 gtcagcacta tcagtatcgt gaatttgcct ggccctggac atttcgcctt acccgtcttt
    11521 tatatacccg gagctggata agcaacgaac gtcctggcct gcttttcgac ctggcgacag
    11581 ggtggcttat gcaacatcgt attattctcc ccggagccac cacgctgacc cggttgattt
    11641 cagaggtaag ggaaaaggcg acgttgcgcc tgtggaacaa actggcactg ataccgtcag
    11701 ccgaacagcg ttcacagctg gagatgctgc tggggccaac tgattgcagc cgcctgtctt
    11761 tactggaatc actgaaaaag gccctgtgac catcagtggt ccggcgttta atgaagcaat
    11821 tgaacgctgg aaaactctga acgattttgg cctgcatgct gaaaacctga gtacactccc
    11881 ggctgtgcgc ctgaaaaatc tcgcacgtta tgctggtatg acttcggtgt tcaatattgc
    11941 caggatgtca ccgcagaaaa ggatggcggt tctggttgcc tttgtccttg catgggaaac
    12001 gctggcgctg gatgatgcac tggacgttct ggacgccatg ctggccgtta tcatccgtga
    12061 cgccagaaag attgggcaga aaaaacggct ccgctcgctg aaggatctgg ataaatctgc
    12121 attggcgctc gccagcgcat gttcgtactt gctgaaagaa gaaacaccgg acgaatcgat
    12181 tcgtgctgag gtgttcagct acatccctag gcaaaagctg gctgaaatca tcacgcttgt
    12241 ccgtgaaatt gcccggccct cagacgataa ttttcatgac gaaatggtgg agcagtacgg
    12301 gcgcgttcgt cgtttcctgc cccatctgct gaataccgtt aaattttcat ccgcacctgc
    12361 cggggttacc actctgaatg cctgtgacta cctcagccgg gagttcagct cacggcggca
    12421 gttttttgac gacgcaccaa cggaaatcat cagtcagtca tggaaacggc tggtgattaa
    12481 caaggaaaaa catatcaccc gaaggggata cacgctctgc tttctcagta aactgcagga
    12541 tagtctgaga cggagggatg tctacgttac cggcagtaac cggtggggag atcctcgtgc
    12601 aagattacta cagggtgctg actggcaggc aaatcggatt aaggtttatc gttctttggg
    12661 gcacccgaca gacccgcagg aagcaataaa atctctgggc catcagcttg atagtcgtta
    12721 cagacaggtt gctgcacgtc ttggcgaaaa tgaggctgtc gaactcgatg tttctggccc
    12781 gaagccccgg ttgacaattt ctcccctcgc cagtcttgat gagccggaca gtctgaaacg
    12841 actgagcaaa atgatcagtg atctgctccc tccggtggat ttaacggagt tgctgctcga
    12901 aattaacgcc cataccggat ttgctgatga gtttttccat gccagtgaag ccagtgccag
    12961 agttgatgat ctgcccgtca gcatcagcgc cgtgctgatg gctgaagcct gcaatatcgg
    13021 tctggaacca ctgatcagat caaatgttcc tgcactgacc cgacaccggc tgaactggac
    13081 aaaagcgaac tatctgcggg ctgaaactat caccagcgct aatgccagac tggttgattt
    13141 tcaggcaacg ctgccactgg cacagatatg gggtggagga gaagtggcat ctgcagatgg
    13201 aatgcgcttt gttacgccag tcagaacaat caatgccgga ccgaaccgca aatactttgg
    13261 taataacaga gggatcacct ggtacaactt tgtgtccgat cagtattccg gctttcatgg
    13321 catcgttata ccggggacgc tgagggactc tatctttgtg ctggaaggcc ttctggaaca
    13381 ggagaccggg ctgaatccaa ccgaaattat gaccgatacg gcaggtgcca gcgatcttgt
    13441 ctttggcctt ttctggctgc tgggatacca gttttctcca cgcctggctg atgccggtgc
    13501 ttcggttttc tggcgaatgg accatgatgc cgactatggc gtgctgaatg atattgccag
    13561 agggcaatca gatccccgaa aaatagtcct tcagtgggac gaaatgatcc ggaccgcagg
    13621 ctccctgaag ctgggcaaag tacaggcctc agtgctggtc cgttcattgc tgaaaagtga
    13681 acgtccctcc ggactgactc aggcaatcat tgaagtgggg cgcatcaaca aaacgctgta
    13741 tctgcttaat tatattgatg atgaagatta ccgccggcgc attctgaccc agcttaatcg
    13801 gggagaaagc cgtcatgcag ttgccagagc catctgtcac ggtcaaaaag gtgagataag
    13861 aaaacgatat accgacggtc aggaagatca gttgggagct ctggggctgg tcactaacgc
    13921 cgtcgtgtta tggaacacta tttatatgca ggcagctctg gatcatctcc gggcgcaggg
    13981 tgaaacactg aatgatgaag atatcgcacg cctctccccg ctttgccacg gacatatcaa
    14041 tatgctcggc cattattcct tcacgctggc agaactggtg accaaaggtc atctgagacc
    14101 attaaaagag gcgtcagagg cagaaaacgt tgcttaacgt gagttttcgt tccactgagc
    14161 gtcagacccc tataactcaa tgagaaaaaa gaattaaagg taaggagacg ctcatgagac
    14221 gttccggcag caaactgtgt cttatcgcca tgataacagc gacagcaact ctcactgcct
    14281 gtgctccaaa gggcagcgtg gaacagcata cccggcatta cgtatatgct tcagatgacg
    14341 gttttgatcc caatttttcc acccagaaag ctgacacaac acgaatgatg gtgccttttt
    14401 tccggcagtt ctgggatatg ggcgcaaagg ataaagcgac cggaaaatca cggagtgatg
    14461 tgcagcaacg cattcagcag tttcacagtc aggaattttt aaactcactc caaggcacaa
    14521 cacaatttgc gggtaccgat taccgcagca aagacctcac accgaaaaaa tcaaggctac
    14581 tggctgacac catttcagct gtttatctcg atggctatga aggcagacag taagtggatt
    14641 taccataacg cgtcattacg cgcaccgctc agacgggctc agggcgtttc cggcggctac
    14701 gggataaaac aggcaacaac ccccccggaa aactgccgga aacgcgcccg ataaatttta
    14761 tcctaatgca tgcctatgca cgcaactgca tggcatatgt tttgacgtaa aatggatgcc
    14821 gtaagccctt ttttaccgac tttctgcttc atcagcctga ctgacacgac catattcttt
    14881 cagaccgccc cctgctaaac ttccttcata ttgccgcatt aacccgggag gctccgcaat
    14941 gagcaacact acacactacg aaaacgccaa ctttcttcgg gaactggctg aaagcctgcc
    15001 ccgcatactg ccggaaggtg gcccggacaa agctgcgctg ttgcagcgac tggctaacga
    15061 agaactggcc caggcagagt atgaagatca ggttcgcgcc aaagtgaccg ccgcccgtgc
    15121 tgacacgcgt ccgggtatga ccacggaaca actccgccag cgcctgcatg gccgttatca
    15181 ggaactgcgc gatgccgtat gacgtggaat ggaagcaggg agccatcgag gatgtaacga
    15241 cgctgtttga ctatatcgcg gaaaattcat
//
