LOCUS       CP088727.1             21053 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CP088727.1 Escherichia coli strain B16EC1113 plasmid pB16EC1113-2,
            complete sequence.
ACCESSION   CP088727
VERSION     CP088727.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 23:07:51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 4227
            Orig. end    :: 25280
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11053]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             42..392
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MEQTLAKVTRIQAGRYAVDDGRCIIKNNSGWLIVDANGAHDFGPV
                     PTLAAAKEYVESGTVPLRQHNFSTSHGRRQSKKEFNAYLASEAKNGNPMPAILWIIVLC
                     IICGIVVAVRGY"
     CDS             476..985
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MATEWVDVADNAVKIGLGALITIVGGWITLKLTHCHEIRKDAIAQ
                     RLRDIDKKTDRYIDFLSSSQTLMQKYLYESCDPGSEDYTNYMRLHNIVSLTSSPELRIY
                     AFDTQSKVSQFILLRKPNEPEVIDSCRNAARNAVSVLQGAVSAELLQDKAALQDKQHAW
                     WAFWRK"
     CDS             1091..2992
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MEIVSFKVSQYRSISGEISSDNFNGLTIVGQNNSGKTNLLKAMRV
                     FFEGKFNPDLYDYEKDKPHGVKQGQTSFAVRFTFSESELDDVSEDLSQDDDDDDDDSII
                     ELGVLGEQEEPSNSISFDDGSSKQQESKPTQSRGRKLSLRDRYLQLFNMIDDSRLNSPQ
                     NEVTVHLTISNKNNYFYTVFKGYKRKPEVTSSMYTSVERRFIEKILSSFECVYIPSSKS
                     IDDIYHNLLVPYVRSEVASAMKTSVQVIHDKLLEVSEKITNEMILSGIDDCSFMIKAPP
                     SLDELFGRFEVSIKDTIENVISSKGMGLQCLSLFSSFKSISERKLTLGKKTIWMVEEPE
                     SFLHPSLGRSCNHIFKSLMDVAYVLITTHSLSFVSDEPSKIIELYKDDAGVTKDKKHEK
                     RFNAVASIRENLGVRFSDFFNISSSAVFVEGITDKQYIESILKLTSEDDEFKNRWPFLR
                     SAKVDEFGGVSQLGGFLKGCYEFISKDVPVISVFDGDEAGVKERTRLQSYFGKKQIRFE
                     SNKDYISVRSGFAIEGLFPDDFISDAMETHPSWFIGGKSVDADDVIEPFKVQDNKKTNL
                     LNFFLEKCRVQPICGWISRWEKVFNVIDSALRDKSESITNKKRTEDTSGNTSDHQAA"
     CDS             complement(3379..3558)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MDFMSILGRCLLLPFPVAMFVGCLFPGIDDRFTGMFMSFIVGCLS
                     WYITKPKPQKAEVA"
     CDS             5145..6179
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MMIQSHPLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQR
                     KGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDY
                     DAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKIL
                     TRKQSGIYTYTLPEKWSDESINWNENKILRPKKLYKNNCAFYGSGKVEGRVIGGNLNTL
                     TGIWGSEWMPEIRNGDILFIEDSRKSIATVERLFSMLKLNRVFDKVSAIILGKHELFDC
                     AGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNISITEQYL
                     STEK"
     CDS             complement(6236..8005)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 133.7;
                     E-value: 9.7e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_12"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 2.6e-21, bitscore:
                     67.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQKITPSKIVKHARELIIKGIESGDNSFVIFDVDGALERLEHYR
                     CQLKSFFPNSSIAYSYKSNNLAQWCQIISGKGLYAEVCSVDEMNLAKRDGFNRIVFDGP
                     LKKTSELLKAIEIGALIEVDNIDECKRLNELCKLHKLTCRIHLRLSHYYDDNLSRFGLS
                     ESEAINLLEMLISKSEYLILDGFHLHVGSNLPNAEKICKAVIQYHELILRYMPDDGTLN
                     LGSGIPADSFSASSDNPTPCPEVFFSSIYDTIKNCFGTVCDKWNYIFEPGRHLVEDFGY
                     FIGKVISTKNRYGVKVAQTNIGINWIPSIRNWDHSFTLFHNHNHISDDKSDEYIIAGFN
                     CFECDCLFPSVILPSNLSDYLFSVRGCGAYDMQTGNQWTRNLYAVYTITNDVVNISRIH
                     RRELDFRKYDVSLTPSGIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVN
                     NISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQ
                     GKGIVTNAINKLIQEYGDSGVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNG
                     VSYDQNIYSKVIG"
     CDS             complement(7990..8793)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 59.8; E-value:
                     4.5e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MTIKHAEELTEEVILNMNYPDFVALMQQDNTPPGAEYTIDYWIKH
                     GCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKY
                     YVADACDLPFEDNTFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKIS
                     DKLINDVYNAINFRPNPLWTLEYWHQFFSERFTLVSEENHEMESQSEDELKADIYDYIF
                     NRNEFTKGLNGSLQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK"
     CDS             complement(8790..10004)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MNTANILSVNYGAYNAIRMLIGVYHAAFLISTGVTISQLAVLQIV
                     FSVTVLILDFPLSVIADRFYRKQVVVSGVFFTILFYPLCIQSPDMLALVFSEIFYAIGI
                     CCISGAIEGWVLSALDGRNEKFTLCAHLCERVSSFGSVITGAVGILVVYFYDSYKSGYI
                     VSFFLMFVVFIVFLCVKTNGSGGEKEARDSIIKQAKESIGLITGSYNGTYFLSITCMFT
                     LGIQVIYHFWQPIMLSGESIGSLSKRELITLLMCHIGAFSMQYIANYFMPKIDVRCKLY
                     ILVCTLCSFLSSIACILLFMLITDNNVVLGVAIFSIIHGMISTIPVGAQNIFISRLNGN
                     YKNIISGALGLVSLSCRVASISVLGVISVLPGNMPVTTYIFISAIACVLCGCLFLMWSF
                     KKEMV"
     CDS             complement(10001..11053)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_15"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 1.6e-20,
                     bitscore: 64.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 8.3e-48, bitscore: 154.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYILGRYVKIARYGSGGLVGGGGKEQYVEDLALWENIIKTAYCF
                     ITPSSYTAALETVNIPEKDFSNCFRFLKENFFIIPSEYNNSTENNRYSRNFLHYQSYGA
                     NPVLVQDKLKDAKVVILGCGGIGNHVSVILATSGIGEIILIDNDQIENTNLTRQVLFSE
                     NDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKVPEADIWVVSADHPFNLINW
                     VNKYCVRANQPYINAGYVNDIAVFGPLYVPGKTGCYECQKVVADLYGSEKENIDHKIKL
                     INSRFKPATFAPVNNVAAALCAADVIKFIGKYSEPLSLNKRIGIWSDEIKIHSQNMGRS
                     PVCSVCGNRM"
     CDS             complement(11755..12141)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MYCWKNILRAPQHERPRVIAVDTEENVFIAESGNEYDGAKCWVVD
                     DDDSHRTRYSELQQAFDFYNQRLFDGELPECLITFQRVTLELFQGKFALSWFDRFPVQV
                     EQQKEMAAVIDQWRETTCSSTSKC"
     CDS             complement(12298..12705)
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MSLTLPLMYFQTGADLSKITHHEVHYQDGFVQQAWLQPEIQLFVV
                     CIARKKGSRREIKGGMAVLTSIPASNGAELAKALDNVMRQSDELRPLAGKDENVFIPAR
                     IGISGEEPPTEQELLSVFYQQCLKHGSWGSA"
     CDS             complement(12760..13224)
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERAERERKRQELLQLIAGEGFSPEELLGLSEEAPKSRKKTLPKAPP
                     KYQFEENGETKYWSGRGRAPKPIAEALASGRSLDEFIIKKDASSSAGDEQ"
     CDS             complement(13240..13446)
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVR"
     CDS             complement(13443..15596)
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLFPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGILSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVLRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVAAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERNVYQAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFCARARKTTDSGFEVFLGAEPTDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQAAIENGDLTVEQFINELYGELTGMISDVDLGEMKIEPAAPAGQFQRLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARTKK"
     CDS             complement(15683..15985)
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MKRICKGLIVIFTVSWLTAPAYAADPCKSVFCLYGKAVGSSGGSE
                     CSSAETDFFKKIEKKKGKIRWSKTFDARKAFLNQCSTADPAAISKIMSKFGRVRG"
     CDS             complement(15982..16395)
                     /locus_tag="ctg1_22"
                     /transl_table=11
                     /translation="MKKILMISILFLTACSSPPEPPQVEWENRPEVMNTQIMNWTPTSN
                     IIKSDNINSSWSKVLPGFKPENRLYDDSVFYAVAHSEKIVVRTSSFDSYWSAKDWLRKN
                     GATGVIEYQPLKRWLNNDYVEIYLSRINIQRLL"
     CDS             complement(16392..18227)
                     /locus_tag="ctg1_23"
                     /transl_table=11
                     /translation="MSLKLPDKGQWVFIGLVMCLVTYYAGSVAVYFLNGKTPLYIWKNF
                     DSMLLWKIITESNIRTDIRLTAIPSLLSGMVSSLIVPVFVIWQLNKMDVALYGDAKFAS
                     DNDLKKSKLLKWETENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPNLLV
                     RKHSLIALDPKQELWKITSKVREILLGNKVYLLDPFNSKTYQFNPLFYIDLKAESGAKD
                     LLKLIEILFPSYGMTGAEAHFNNLAGQYWTGLAKLLHFFINYEPSWLNEFGLKPVFSIG
                     SVVDLYSNIDRELILSKREELEGTNGLDENALYHLRDALTKIREYHETEDEQRSSIDGS
                     FRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDISLAYDFLNLFFNFVVE
                     VTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGAGYIAGFKLKLLTIYQNISQLNE
                     IYGIEGAKTLMSAHPCRIIYAVSEEDDAAKISEKLGYITTTSKSTSKSRGRSASQGESE
                     SEARRALVLPQELGTLDFKEEFIILKGENPVKAEKALYYLDPYFMDRLMKVSPKLASLT
                     MELNKTKKIFGVKGLKYPSKEKMLSVGELESEVLL"
     CDS             complement(18230..19261)
                     /locus_tag="ctg1_24"
                     /transl_table=11
                     /translation="MNNENRHLIYDVVNDYFYHWLNEIEGVTEIAVNRPGEIFIKVRGK
                     WQWYEQKMSYSDCLSFASTLADFHDGGSVTPEYPLRSATLPGGERVQVVIPPATEKDTV
                     SITIRKPSGIFINHDKFIKQGFYSRIGGLSSDSVMEDNISALITSGYFERVIPESLSQG
                     KTIVFCGGTGSGKTTFANACLEYIPHHLRCISIEDTDEAKFRFHKNHVKLYYPAEGESK
                     IITSASLLRSCFRMNPDRILMTEIRGAEAWDFLKASSSGHAGNITTVHESSPEYAVLGI
                     VQRCYMNPECQNLPFNVILRRVLSNIDIIMSIKYLDDEDFRFASGIYYRQLHFDDYFRK
                     LKE"
     CDS             complement(19263..20468)
                     /locus_tag="ctg1_25"
                     /transl_table=11
                     /translation="MTEQENKIPTATEIEQQLRERRQKELEQAGKTPEEEPGKPALQLG
                     IEKLKKSRKGMIILVVGFLLLAAGVSVYYIPSIIRSVSSGDEKPASQPLATGAAKRQTG
                     LSEDIDPFNTAQKKTEKPEEEKVISSEKTEPPENKQQSFSRALDVSLDGSQAGNSSSSA
                     GTSVSHTAASEPESDKKDEAKATAQTTESAPLAKITKLPYDPNLFIPEGTSIPCSLDRR
                     FVSDLAGKLECTVNSDIYSASGNVKLIERGTAAKLMYKAGSLNHGQGRVFVMAYKLRTR
                     SKPFIDIPLIDSQAAGALGEAGASGWIDTHFGERFLGAMMVGMIPDLSQAASGIAQNNR
                     DSQTDYTANSRQAFADIAREAFSNSVNIPPTLYKNQGEIITLIVGQDLDFSGIYKLKMK
                     GG"
ORIGIN
        1 ttttactgat gaacaaagta gcccgttggg cataagacaa catggagcaa accttggcta
       61 aggtaaccag aattcaggcc ggaagatacg cagtcgatga tgggcgttgc attataaaaa
      121 ataactctgg gtggcttatt gtcgatgcta atggcgctca tgattttgga cctgtcccca
      181 cattagcagc agctaaggaa tatgttgagt ctggtactgt tccgctaagg cagcacaatt
      241 tttctacatc tcatggtcga agacaaagta aaaaagaatt taatgcgtat ttggcatctg
      301 aagctaaaaa tggcaatcca atgccagcca ttctttggat aattgtcctt tgcatcatct
      361 gcggcattgt agttgcagtt cgaggttatt aatcttggac agaaaatgct gtatgtccag
      421 tcagccggag aattatacta gcgaccatga tcatcacagg aagaacgcgt aacagatggc
      481 aactgagtgg gtagatgtgg ctgataatgc cgttaaaatt gggctgggtg cattaatcac
      541 cattgttggt ggctggatta cactgaaatt aacacactgc cacgaaataa gaaaagatgc
      601 aatagctcag cgactgcggg atatagataa aaaaactgac cgctatatag attttctttc
      661 ttcatcgcaa acgctaatgc agaaatatct ttatgaatca tgtgatccag gtagcgagga
      721 ctacaccaat tatatgcggt tgcataatat tgtaagcctg acatcctccc ctgaattgcg
      781 aatctatgct tttgatactc agtccaaagt atcgcaattt atcctgctca gaaagcccaa
      841 cgaaccagag gttattgatt cctgtcgcaa tgccgcgaga aacgccgttt ctgtgcttca
      901 gggggcagtg agtgctgaat tgcttcagga taaagcagca cttcaggaca aacaacatgc
      961 atggtgggct ttctggcgaa aataaagcag aacagtggag gaagagccat ttatccaagt
     1021 agcgaaatac agttaaagcc ttgggaaaaa atgtcgataa tccgagcaat attctatcgt
     1081 aggaagaaaa atggaaatag tatcatttaa agtttctcag tataggtcta tttcagggga
     1141 gatatcctct gataacttta atggattaac cattgttggg caaaacaaca gtggtaaaac
     1201 aaacctatta aaagctatga gggttttttt tgaaggaaaa tttaatcctg acttatatga
     1261 ctatgaaaaa gataagccac atggtgttaa gcaaggacaa actagttttg ctgtaagatt
     1321 tactttttct gaaagtgagc tagatgatgt ctctgaggat ttgagccaag acgatgatga
     1381 tgacgatgat gactcgatta ttgaacttgg tgttttaggg gagcaagaag aacctagtaa
     1441 ttctatttca tttgatgatg gcagctctaa acaacaagaa tcaaaaccaa ctcaatcaag
     1501 aggcagaaag ctaagtttga gagatagata tttgcagctg tttaacatga ttgatgactc
     1561 caggttaaat tcacctcaaa acgaagtgac cgtacatctg acaatatcta ataaaaacaa
     1621 ttacttttac actgtcttta aaggttacaa gaggaaacct gaagtaactt cctccatgta
     1681 tacatctgtt gaaagaaggt tcatagaaaa aatactttct agttttgagt gtgtgtatat
     1741 accatcgtca aaaagtattg atgatatata tcataatcta ttagttccat atgttaggag
     1801 tgaagtagct tcagccatga aaacatcggt tcaagtgatt catgataaac tgttggaagt
     1861 gtctgaaaag ataacaaatg aaatgattct aagcggtata gatgactgta gctttatgat
     1921 taaagctccg ccatctcttg atgagttatt tggtcgcttt gaggtttcaa taaaagatac
     1981 tattgagaat gtgatatcga gtaaaggtat ggggctacaa tgcttatctt tattttcttc
     2041 atttaaatct atttcagaga gaaaacttac tctaggtaag aaaacgattt ggatggttga
     2101 ggagcctgag tctttcttgc atccctcatt aggccggtca tgtaatcaca ttttcaaatc
     2161 actgatggat gttgcttatg ttcttattac aactcattcc ttatcatttg tcagtgatga
     2221 gccaagtaag atcattgagt tatataaaga tgacgccggt gttacaaaag ataaaaagca
     2281 tgaaaaaaga tttaatgcag ttgcaagcat aagagaaaat cttggggtca gattttctga
     2341 tttctttaac atatcaagta gtgcagtttt cgttgaaggt atcaccgaca aacaatatat
     2401 agaatcaata ttgaaattga catctgaaga tgatgagttt aagaacagat ggccttttct
     2461 gaggagtgct aaagttgatg agtttggtgg agtcagtcaa cttgggggat tcttgaaagg
     2521 gtgctacgag tttatttcta aagatgtccc cgtaatatct gtttttgacg gtgatgaagc
     2581 tggggtcaaa gaaagaacca gattacaaag ctactttggt aaaaaacaaa ttagatttga
     2641 gtcaaataaa gactatattt ctgtaagaag tggttttgct attgaaggcc tcttccctga
     2701 cgatttcatt tctgacgcaa tggaaaccca tccgtcgtgg tttatcggag gaaaatctgt
     2761 tgatgccgat gatgtaattg aaccattcaa agtgcaagat aataaaaaaa ctaacttatt
     2821 aaatttcttc ctggaaaaat gtcgtgttca acctatatgc ggttggattt ctcggtggga
     2881 aaaggtgttt aacgtcatag actcagcctt gcgagataaa agtgaatcca tcacaaacaa
     2941 aaaacgaacc gaagatactt ccggtaacac ttcagatcat caagctgcat aatcgattgt
     3001 gtgcaccaag gttgcacata cacctgatta atcaagagtg agaccataac aagcctatat
     3061 cagataacag ccctcttcat aagagggctg tctttttcgc gggcatcgta cttgggttcc
     3121 acttggaaaa tggaaaacat cctacgctaa gagcgttttt taaacaaccg gcttgttggt
     3181 ttttacgaga tactgtgcag ttgaaggaac aagataaagg aattaaagac cctttagtac
     3241 catactttca tgaaattttc ccatattttc ttttagatcg tgcaacagcg aaaagacgta
     3301 ggaattggct tgattagccg caatactatt tctggacaga atggcgagga attaaacgag
     3361 aggcgtaaaa aaggccgctt acgcgacctc agccttttgc ggttttggct tggtgatata
     3421 ccacgataga caaccgacaa taaaactcat gaacattcca gtaaaacgat catcaatgcc
     3481 tggaaacagg caaccgacaa acatcgcaac agggaaagga agaagtaaac agcgccccaa
     3541 aatgctcata aaatccataa cacctccttt gttaaagggc aggaagcggt gcacttcctg
     3601 cccttagtta cgtttccgca gtcatcaatc gatgaactga cggatcagtt ccagaactgc
     3661 aatcagcgcg tttgcaagcg cagctaccgc cctcagaacg atgattaaca ggttaatcat
     3721 ccgttttctc cataaatgga gtaaagacac cgtggcttgc tcttacgctg cctgtcacca
     3781 cggcttctct tcgtcttgtc agttgtagag agtctcactc ctaccagagc acagataacc
     3841 agcaccacct gtattacctg tcaggacttt gaagctgttc atgccgcatt tagcggaatg
     3901 cagggaaaga ctcaccacag cactaaccct ctgattatac gtttatctaa ctttcaagca
     3961 aaccgttaac gcgtagtcac cgcctgtcat attgcataat caggcttcac ggattatcat
     4021 actgttgtca gttgtagaga gtttctcttc cgggcgagtt accagctcgt accggaactg
     4081 taaaaaagcc gacctcacca gtcggttttt ttacgtctgc agtttcccgc ttcatttaga
     4141 tctattttaa atgaataaat tttctgcggc aaacccaacg acgttgggtc gttagtgtaa
     4201 ataattgttc aaaactcata aacactcctt tgttaaaggg caggaagcgg taaacgtctc
     4261 tcccttagtt aagccatcaa tcactcgatt agtttctgaa tggcaatcag cgcgtttgca
     4321 acggcgacca cagccctgag aacgatgatt aacaggttaa tcatccgttt ctccaggttg
     4381 atactggagg aagtcgccgt tgcttgctca tacatcgcct gtcacaacgg ctctctcaca
     4441 ttgttggatg tagagtacct tccccctgcc agagcactga acacagcacc acctgtttgt
     4501 tcagccagga ctttaattcg ttcataccca gatagcgcag ggtttagaag caagggaggc
     4561 acactgtaca gcgccaacac aaagattata cagatgcacg cataaaattc atttaaagaa
     4621 atggccattg acagacaatc tgaagtcaaa ctagacaact ggtgtctagt gccataatat
     4681 tgtggatgtt ggatgtagag tatcttcctc cagtcagagc caccaactca ggactggaaa
     4741 acacaaaaaa gcccgattac cagtcgggtt tttttgtgcc tgtcgttcag ctgtacttcc
     4801 gttttttccc cttcatttga gggaattttc tttcagtttt tttgttgtgt ccaatgctac
     4861 cggtcgcgta ggccaacagg tcaatgccgt taccggcatt ttcatgaatc cagttttttc
     4921 agtaagttgc agcacaacag atgattaaaa aagctatcag tttttttgat ggatacagta
     4981 gtggcggtgc gctacgtgaa ctctgaggct tttcgggggg ggattggacg agaaaattta
     5041 cgagagaaca ctgcgatttt caaaaaaagc ccataaactg aaagtgctac tgacatatct
     5101 caaaacgggt tcattttgac actaaatgga aaggaaaaat cctcatgatg atacaatctc
     5161 atccgctact ggccgctccc ctggcagtag gagatacaat tggtttcttt tcatcatctg
     5221 ctccggcaac agttactgca aaaaatcgtt tttttcgggg agttgagttt cttcagagaa
     5281 agggatttaa gctggtatca gggaagctta ccggtaaaac agatttttat cgttcaggta
     5341 ctattaaaga aagagctcaa gaatttaatg agttagtcta caatcctgat attacctgta
     5401 taatgtcaac gatcggtgga gataacagta attcactact accgtttctg gactatgatg
     5461 ctatcattgc aaaccccaaa attatcatag gttactcaga tacaactgct ttattagcag
     5521 gaatatatgc aaaaacaggg ttaataacat tctatgggcc agctcttatt ccttcgtttg
     5581 gtgaacatcc acctcttgtg gatataacat atgaatcatt tattaaaata ctaacaagaa
     5641 aacaatcagg aatatatacc tacacattac ctgaaaagtg gagtgatgag agcataaact
     5701 ggaatgaaaa caagatatta aggcctaaga aactatataa aaacaactgt gccttttatg
     5761 gttccggaaa agttgagggg cgtgtaattg gaggaaatct aaatactttg acaggtatat
     5821 gggggagtga atggatgcct gaaattcgga atggagatat attgtttatt gaggacagtc
     5881 ggaaaagcat tgcaacagtt gaacgattat tctctatgct aaagcttaat cgcgtgtttg
     5941 ataaagttag tgcaataata ctcgggaaac atgagctttt tgattgtgca ggaagtaaac
     6001 gcagaccata tgaagtatta acagaggtat tagatgggaa acaaattcct gtactggatg
     6061 gatttgattg ttcacataca catccaatgc taactcttcc acttggtgta aaattagcta
     6121 ttgactttga caacaaaaat atatctataa cagaacaata tctatctacc gagaaataaa
     6181 tattatcatc tcacagacat aaacaaaatg gcgtagaata ctacgccata cagtattaac
     6241 caattacttt cgaataaata ttttgatcgt atgatacacc gttgagtatt tctgcttttt
     6301 gcagaacacc ctctaaggtg aagccacacc tcaatgccgt ggcattactt tttttattat
     6361 caacaataca ttttataaca aatcttttta taacgcccga atccccatac tcctgtatca
     6421 gtttatttat agcattggtt acaatcccct ttccctgaaa gttagcgcct aaccaatagc
     6481 caatatatgc tgttttattg gcatggtcaa taatattaaa agatacaacg ccagctatct
     6541 tagttttgta tttaataaag aggattaatg ctttttcatt ctggttatca atcattgatt
     6601 gctcaatgaa agaaacagaa tcagaaatgt tattaacaaa cgctggccat gccatgcttt
     6661 taatgaaatt tattttgttt tgattaatga gcaaatataa ctcttcagcg tattttaacg
     6721 ctggatacaa taatgtaatc tcatcattta cttttattcc tgatggcgta agagatacat
     6781 catacttccg gaaatcaagt tctcttctgt gaattcttga tatattaaca acatcatttg
     6841 ttatggtata tacagcataa agattacgcg tccactggtt tcctgtttgc atatcataag
     6901 caccacaccc tcgaacagaa aataaataat cagataagtt actgggaaga ataactgaag
     6961 gaaacaagca atcacattca aagcaattga atccagcaat aatatactca tcagatttat
     7021 catctgaaat atggttatga ttatgaaaca atgtaaatga atggtcccaa tttctgatcg
     7081 aaggtatcca gtttatacca atgttagttt gagcaacttt aacaccatac ctgtttttag
     7141 tactaataac tttccctata aagtagccaa agtcttcgac cagatgtctc cctggttcaa
     7201 aaatatagtt ccatttatca catacagtac cgaagcaatt ttttattgta tcatatatcg
     7261 atgagaaaaa tacctccgga catggagttg ggttatcact ggatgctgag aaagaatctg
     7321 caggtatccc actaccaaga ttaagagtgc catcatctgg catataccta agaatcaact
     7381 catgatactg tataacagct ttacatattt tttccgcatt gggtagatta gagccaacat
     7441 gtaaatggaa cccgtctaaa atgagatact ctgacttact gatcaacatc tccagtaaat
     7501 taatagcctc actttcagat aagccaaatc ttgataaatt atcatcatag taatgcgata
     7561 atctcaaatg aattctacat gtcaacttat gcaatttaca tagttcatta agtcttttac
     7621 attcatcaat attgtcaact tcaattaatg ccccaatctc tattgccttt aatagttcac
     7681 tcgttttttt taaagggcca tcaaaaacaa tccggttaaa accgtctctt ttagcgaggt
     7741 tcatttcatc aacagagcac acctctgcat acaaaccttt acctgagata atctggcacc
     7801 attgtgccag attatttgac ttatatgaat atgcgatact gctgttgggg aaaaaactct
     7861 taagttgaca cctgtaatgt tccagacgct ccagagctcc atctacatca aaaatgacaa
     7921 atgagttatc gcccgattca atccccttaa taattaactc ccgggcatgt ttaacaattt
     7981 tagatggtgt tattttttgc gccatatttg caatgtaact ccctgataat ctctttggat
     8041 atttaatggt ctgcgtattt ttaaaaatct ttcaaaaaat acattctgaa gtgaaccatt
     8101 caaacctttt gtaaactcat ttctattgaa aatgtaatca taaatatcgg cttttaactc
     8161 atcttcactt tgagattcca tctcatgatt ttcttctgaa accagagtaa atctttcaga
     8221 aaaaaactga tgccagtatt ccaaagtcca caaaggattg ggtctgaaat ttattgcatt
     8281 atatacatca ttgataagtt tatctgatat tttacgcctg taataaaaat ttgaaatgca
     8341 catgcttccc atgtggttta aacatcgatg agtttcattc aaggctatta accgattttg
     8401 tataaatgca aaattacatc caccgagaac atgtgtaaaa gtgttatctt caaatggtaa
     8461 atcacaagca tcagctacat aatatttcaa taaattatta gccttaagct tttttgcctt
     8521 ttcatttgcg accattacag ctgattcaga tatatcaata ccctctgcag atgcaccttc
     8581 ttttttgaag cattcacgtg aactaaaacc cgtggaacat gctaaatcta ataggtgaga
     8641 ctttttgtta atacatccat gcttaatcca gtagtctatg gtgtactctg ctccaggagg
     8701 agtgttatcc tgttgcatca gagcaacaaa atcagggtaa ttcatattta aaatgacttc
     8761 ttccgtcaat tcttcagcat gtttaatcgt cataccatct cctttttaaa ggaccacatt
     8821 aagaacaaac aaccacacag tacacatgca attgcagaga taaatatata agtggtgaca
     8881 ggcatattac ctggtaatac agatataact cccaacacag aaatggaagc aacacgacat
     8941 gaaagagaaa caagaccaag agctcccgaa ataatattct tataattgcc attaagtctg
     9001 cttatgaata tattctgtgc tccaacaggt attgttgaaa tcatcccatg gattatagag
     9061 aaaatagcta caccgagaac aacattatta tctgttatta acataaatag taaaatacag
     9121 gcgattgaac taagaaatga acataatgta caaacaagta tataaagttt acatcttaca
     9181 tctatctttg gcataaaata gtttgctata tattgcattg aaaatgcacc aatatgacac
     9241 atcagtaaag ttataagctc tctttttgat aatgagccaa tactttcccc agataacata
     9301 attggctgcc aaaaatgata aattacctgt ataccaagtg taaacataca tgttatagat
     9361 aaaaaatatg tcccattata acttcctgtt atcaatccaa tactctcttt tgcttgttta
     9421 ataatactat ctcgtgcttc tttttcaccc ccactgccgt tagtttttac acataaaaaa
     9481 acgataaaga caacaaacat caagaagaac gatactatat agccagattt ataagaatca
     9541 tagaagtaga caactaatat tccaacagca ccagttatca cactcccaaa ggaagatacc
     9601 ctttcgcata aatgagcaca taaggtaaat ttttcatttc taccatccag agcacttaac
     9661 acccatccct ctatagcccc agatatacaa caaataccaa tggcataaaa tatttcagaa
     9721 aaaaccaatg ccagcatatc aggagactga atacaaagag ggtaaaataa aatagtaaaa
     9781 aatacgccac taactacaac ctgtttcctg taaaatctgt ctgcaatgac agataaagga
     9841 aaatcaagaa tcagcactgt cacagaaaaa acgatttgta aaacagcaag ttgagatata
     9901 gtaacacctg tagatataag aaatgctgca tggtagacac caattaacat acgtatagca
     9961 ttataagctc catagttcac agataaaata tttgcagtat tcacattcta tttccacaca
    10021 cagagcaaac aggcgaacgg cccatatttt gggaatgtat ttttatttca tctgaccaga
    10081 tgcctattct tttattaagt gataatggct cggagtattt tccaatgaac ttaattacgt
    10141 ctgccgcaca taatgcagcg gcaacattat tcacaggtgc aaatgttgct ggtttaaatc
    10201 tgctattgat tagcttaatc ttatgatcaa tgttttcctt ttctgaacca tatagatctg
    10261 ccacgacttt ttggcactca taacatcctg ttttaccagg aacatataat ggaccaaaga
    10321 ctgcaatatc attaacatac ccagcattta tatagggctg atttgctcta acgcaatatt
    10381 tattaaccca gttgatcaga ttaaatggat gatctgcaga aacaacccat atatcagctt
    10441 ctggtacctt atgaagatca gtgtaatcgt ttatattcaa agcgatttca gacaccgaaa
    10501 tttcagagtt tctttttaat aactcgcgtt ttataacttc tgttttattt ttaccgacat
    10561 cattctctga aaataaaacc tgccttgtca aatttgtatt ttctatttga tcattatcaa
    10621 ttagtataat ttcgccaata ccagacgttg cgagtataac agatacatga tttcctatac
    10681 ccccacaacc aagaattact accttagcat cttttagttt atcttgcaca agaacagggt
    10741 tagcaccata actttgataa tgtaaaaagt tacgagagta acgattattc tcagtagagt
    10801 tattatactc actaggtata ataaagaaat tttccttaag gaacctaaag caattagaga
    10861 aatctttttc aggtatattg acagtttcca acgctgcagt ataactcgat ggggttatga
    10921 aacaatatgc ggtttttata atattttccc aaagcgctaa atcctcaaca tattgctcct
    10981 ttccgcctcc accaactaat ccaccgctcc cgtatcgagc aattttgaca tagcgaccca
    11041 atatataatc cataaataaa cctcgcagat aaattttgta tgccaccctg tacagggtgg
    11101 catttaatgg acatttatat tttgccatta gtttgcatta ccagtacgca ttctacgcct
    11161 cctattactg tgattaattc acaagtgttt ttatcactat aaaaaacaat attcctcatg
    11221 aaaatataca aacatagatt catttcacaa aaaaagaaca gcacaatcat attatttgcg
    11281 gttatacatt tttattctaa aatttattaa tttatatatt tagacataaa taaccataca
    11341 gaatataatc atctatgttt aaaccatttt gtaataaaaa tttgatacat ccatcgttca
    11401 ttacattcga aaccaataat cctgattacc agtcacgttg agaagccact caatgagcgg
    11461 tggtgcgcta cgtgaaatct gagttttttc gggtcggatt ggacacgaga atttatgaga
    11521 aagaatcagg aaatgccacg aaaatggaga ttaattttcg atgaaaggca gctcgcaatc
    11581 accgcattca atattcactc cggacttccc ccagacagca gcaccacacc ccgacactga
    11641 tatttgactt tgttcctttt tggcttgtcc tcaaaagccg caacaaacag atcgttatca
    11701 ttgctcccgt tctacggtga cactgacagc accggcttca atatcaatcc cggttcagca
    11761 ttttgatgtg cttgagcaag tagtttcccg ccattgatcg atgacggcgg ccatctcttt
    11821 ttgttgttca acctggacag ggaagcgatc aaaccagctc aaagcaaatt taccctgaaa
    11881 cagttccagt gtgacgcgct ggaacgtaat cagacactcg gggagttcac cgtcaaaaag
    11941 gcgctggtta tagaaatcaa acgcctgttg tagctcgctg tagcgcgttc tgtggctatc
    12001 gtcatcatcg acaacccagc atttcgcgcc gtcatattca ttgccacttt ctgcaataaa
    12061 cacgttctct tcagtatcta ccgctatcac tctggggcgc tcatgctgag gggcgcggag
    12121 aatatttttc cagcaataca ccttcccgtc ctaactcaga atcacacccg aatctgcgtg
    12181 ctccgggttg tgctgacgcc ataccctggc aatatcaagc ccaggaagag catcgagcgc
    12241 gtaatattgc tggcaagaaa ggtaagcagg gggtatccct gctttatgta ccagaaatca
    12301 ggcactgccc catgagccat gtttcagaca ttgctggtaa aagacactta gaagctcttg
    12361 ctctgttggc ggttcttcgc cagaaattcc aattctggct gggataaata cgttttcgtc
    12421 tttccctgcc agtggccgca actcatcaga ctggcgcata acgttatcca acgcttttgc
    12481 caactccgct ccattgctgg ccggaatact ggtcagaacg gccattccac ctttaatctc
    12541 gcgacgggag ccttttttcc tggcgataca cacaacaaat agctgtattt caggttgcaa
    12601 ccatgcctgc tgaacaaagc cgtcctgata gtgcacttca tgatgtgtga ttttgctgag
    12661 atctgcacct gtctggaaat acattaatgg taatgtcaga ctcaaaacat cctcctgttt
    12721 atcaaaaaag tctcctgcgt aaaccagaag cctattatat tactgttcgt cgccagcaga
    12781 gctggaagca tcttttttga tgataaactc atcaagagag cgaccgcttg ccaatgcttc
    12841 agcaatcggt tttggcgcac gcccacgacc agaccagtat ttcgtttcac cattttcttc
    12901 aaactgatat ttaggcggcg cttttggtaa cgtttttttt cgtgattttg gtgcttcttc
    12961 agacagacca agcagttctt ccggtgagaa cccctctccg gcgattaact gaagcagttc
    13021 ctgacgtttc cgttcacgct ctgctcgttc agccgcttca cgttcagcat cttcacgacg
    13081 ttcttcaata acaacgttga gcttttcctg catttcgagc aactgctcaa aatcaatctc
    13141 acgggcaaac acacgcaatg aacgaatatt catcatagtc cggctgataa tgccgtattc
    13201 atcttcttta gtcagttcgc tcataattaa tcctcttgtt tagcggacgt acttccagac
    13261 gccggaagga accttatcat aaagtttatt cataaccagt tctgcgcggc gatggtctgc
    13321 ggcagaataa aatgcctctg attctgataa aggcagcttg taacggttaa tctcaataac
    13381 tttttcaaga gtatctcttg atgtacattt tcttaactga aaaagccatt cctgctttgt
    13441 tttcacttct tagtccttgc cggaaaaccc agcttccctg ttttcttatc ctcaaggaca
    13501 agaactgtat catacgttcc accacttttc tttttaaatc ccttaatcaa atcggttttc
    13561 cctgatttaa ccagtttttc ggcctgtgcc tgggtgattt tcttaccaga aaactcactc
    13621 cagattttaa attcacatcc ggtacagaaa taaccttttg gcctgataac aatatgctta
    13681 ccacaggaag ggcagggaga atccaggcgt tgaaactgcc ctgctggcgc agcaggttca
    13741 atcttcatct cgcccaggtc aacatcagaa atcatgcctg tcagttcccc gtacagctca
    13801 ttaataaact gttcaaccgt caggtcgcca ttttctatgg cagcctgctt ttcagaccat
    13861 aatgctgtca tatcaggatt aactgctata ccaggcaggg catcaataag cgcatatccg
    13921 gtatcagtag gaataagttt ccctttttcc agcgtgatat agtttctttt cttcagcgtt
    13981 tccagaatgg ctgcgcgggt agctggcgta ccaatgccac catgttcatc ttttttgtct
    14041 ttatccttat ccttcaacaa ttttttaatc gttggatcag tgacaaaatc cgcgacacga
    14101 acaagcgcag caagcaagga ggcttcggtg aataacggcg gcggtgttgt tttcttctca
    14161 ttaacaacaa cttcttttgt cgtcagtgtt tctcctgtgc gaattttaca gagcagttca
    14221 aaagcggaat catcattatc ttctgattca ccttcgtctg tgggttccgc gccaagaaat
    14281 acctcaaatc cgctgtcagt tgtttttctg gcacgggcac agaacgactc atcaccacac
    14341 tgaatggcaa ccgatacttc ctggtatgct ttttcaggca tgaactgaac aagatagtgt
    14401 tgtgcgatcg cctggtaaac attgcgctcg tcggtgctga gtgcgttaac atcaggcaca
    14461 ctggcggtcg ggattatcgc agtatgcgca gtcacctttg cactgttaaa cgctttgctt
    14521 ttacgtgcag aatcaatatc cagcgactga ggaaagactg atttcagggc atcgataacc
    14581 tgcggcgctt cgctgaattg ttcatcagaa agatatgagc aatctgagcg gttataagta
    14641 attgctttat atttttcacg tagttgttgc gtaatatcca gcgttttttg tgccgtcatt
    14701 ttaaacttct tgttcatgta ttgctggagt ctgaccaggt taaacggcaa cggcgcagcc
    14761 gtttttttat catcagttgc tgctgctgca actgtagccg gttttcctgc aagggatgct
    14821 gccgttccgt ctgcccacgc cttatcaagt aatttacggt cggtcagcgg agcaaattca
    14881 cctggtttcc agttcgccct gagaacatca gcaccacgct gaaaaactcc ggtcatggtg
    14941 tagtaaaaac tggatttatg gttctggtta gcacgggtac gattcacaat caggccaaga
    15001 acgggtgtct ggacgcgccc gactgacaga atgccctgat atcctctggc ttttgcagga
    15061 atggtgtaag cacgcgtcat ggagaatcca tagacggcat cggcaactga acgcgccagc
    15121 gccttaaggt aaagcccttt gaaatcacga ttatctttaa gatttgccag tgcctttttc
    15181 actgccggaa gcgtgttgtc gtttatcaga acgcgcttca cgggttttgt gtttcctgca
    15241 tattccagga cttcatcaac aagtagctgc ccctcgtcat caggatcgcc agcgtgaaca
    15301 atttcagtca cgtctccacg tctgataagt tcgagaatcg ttttaacctg ttttgcggca
    15361 ctttcgacag gctggtactt cacgggaaaa agacgtaaag gaagcgtttc aaccttccag
    15421 gctttgtatt caggattata gttttccggc ggctgtgatt cgataatatg accaaagcaa
    15481 ttagttacaa tagcattatc actttcaaac cagccatcat ggcgggtaaa gttgccacca
    15541 agtgccttaa caatatcatt tgctactgcg ggtttttcag cgataaaaag tctcattaat
    15601 tacacctcaa ttcaggttat gtactattct attttctcta tatgtatccc tgatacccgt
    15661 tggttcgggt atcaggtttt aactaacctc tgacacgacc aaacttactc atgattttcg
    15721 atatagcagc aggatcagcc gttgaacact gattaagaaa tgccttgcgg gcatcaaatg
    15781 ttttactcca gcgaattttt ccctttttct tttcaatttt tttaaaaaaa tccgtttcgg
    15841 cactactgca ctcactccct ccactactac cgacagcttt accataaaga caaaaaacag
    15901 atttacaggg atcagcggca tacgctggcg ctgtcagcca ggacacagta aaaattacga
    15961 ttagaccttt gcatatcctt ttcatagtaa cctctgaata tttattcttg acagataaat
    16021 ttcaacatag tcattattca accatctttt tagtggctga tattcaataa cacctgttgc
    16081 accatttttt cttagccagt ctttcgctga ccagtaacta tcaaaagaag atgtccttac
    16141 aactattttt tcagagtggg caactgcata aaaaacagaa tcatcgtaaa gacgattttc
    16201 tggtttaaaa ccaggtaaca ccttactcca tgaggaattt atattatctg atttaataat
    16261 gttggatgtt ggtgtccagt tcattatttg tgtattcata acttcaggcc gattttccca
    16321 ttcaacctgt ggcggttcag gtggagagga acaggctgtg aggaaaagaa tactgatcat
    16381 aagtattttt ttcataataa aacctcagac tccagttctc ctacggagag cattttttct
    16441 tttgacggat atttaagccc tttcacacca aatatttttt tcgtcttatt tagttccatc
    16501 gtcaatgatg ccagtttagg actgaccttc attaacctgt ccataaaata cggatcaagg
    16561 taataaagtg ccttttctgc tttaacaggg ttctccccct tcaggatgat aaactcttct
    16621 ttaaagtcca gcgttcccag ctcctgtgga agcaccagtg ctcttcgggc ttcactttct
    16681 gattcgccct gtgaagctga tcgtccccgg ctcttgcttg tgctctttga tgtggttgta
    16741 atatacccaa gtttttctga tatcttcgcg gcatcatcct cttcgctgac agcatagata
    16801 atacggcatg gatgagcact catcagcgtt ttggctccct caataccata gatttcattt
    16861 agctgactga tattctgata aatcgtcagc agtttaagtt taaaacctgc aatataccct
    16921 gccccctttt taataattgg catataacca atcgaaggga actcatcaag aaacatcaga
    16981 cagtcatgtt tcagggtggg atcaaaatca ggattttcac gcaatgtcac ttcaacaacg
    17041 aagttgaaaa acaggttcag aaaatcgtaa gccagagata tatcttccgc attaacaccg
    17101 acataaacag tgatatcttc ccgtcgcaac tgacgaagat cgaaatcatt accatcagta
    17161 catttacgaa cggttgggag ataaaacagg ctcattttct tacggaaaga accatcaatg
    17221 cttgaacgct gttcatcttc cgtttcatga tattccctga ttttggtcag ggcatcgcgc
    17281 aaatgataca acgcattttc atcaagcccg tttgttccct ccagttcttc ccgcttactg
    17341 agtatcagtt cccggtcaat attgctgtac aagtcgacga cagaaccgat tgagaaaacg
    17401 ggtttaagcc cgaactcatt aagccaggac ggctcatagt taataaagaa atgaagcaac
    17461 ttagccagtc ctgtccagta ttgaccagca agattattaa agtgcgcttc tgcccctgtc
    17521 atgccataag acggaaacag aatttcaatc agtttaagca gatccttagc cccactctcc
    17581 gcttttaaat caatatagaa aagggggtta aactggtatg tcttactgtt gaaagggtcg
    17641 agcagataaa ctttattacc cagcagtatt tcacgcacct tactggtgat tttccacaat
    17701 tcctgttttg gatctaacgc aataagagag tgttttctga ccagaagatt agggatacca
    17761 atggcggcac ctttaccggc gcgggttcct gcaccaagag atacaaaatc cggggcggta
    17821 taccacagat attttccttt atacgctccg accagaatat ccgtatcatt ttctgtctcc
    17881 cacttaagca gttttgattt ttttaaatca ttgtcactgg caaacttcgc atcaccataa
    17941 agagcaacat ccattttatt cagttgccag ataacaaaaa caggcacaat gagagacgaa
    18001 accatacctg acaaaagaga gggtatggca gtcagtctga tatctgtacg tatattactc
    18061 tctgttatta ttttccagag caacatggag tcaaaatttt tccatatata cagtggtgtt
    18121 tttccgttca ggaaataaac agcaacagaa ccagcataat aggtcacgag acacataacc
    18181 agaccgataa aaacccactg gcctttatct ggaagtttta aagacataat cactccttca
    18241 gttttctgaa ataatcatca aaatgaagtt gtctgtagta aatgccggaa gcgaaccgaa
    18301 aatcttcatc atcaaggtat ttaatactca tgataatatc aatattactc agtacacgtc
    18361 ttaaaatgac attgaatggt agattctgac attcaggatt catataacat cgctggacaa
    18421 tcccaagcac ggcatattca ggactacttt cgtgaacggt ggtaatgttt cctgcatggc
    18481 ctgaactcga tgctttcaga aaatcccatg cctcggctcc cctgatttct gtcatcagaa
    18541 tcctgtccgg attcatacga aaacaggaac gcagaagact cgctgaggta ataatcttac
    18601 tctccccctc tgccggatag taaagtttta catggttttt atgaaatctg aattttgcct
    18661 catcagtatc ttcaatagaa atacaccgca gatgatgcgg tatatactcc agacaggcat
    18721 ttgcaaaggt agttttacca gaccccgtcc ctccacagaa aactatcgtt ttcccctgac
    18781 tcagtgattc aggtataacc cgttcaaaat atccggaagt gattaaagca gagatattat
    18841 cttccataac ggaatcacta cttaaaccac cgatgcgtga ataaaacccc tgttttataa
    18901 atttgtcatg attgataaaa atacctgacg gcttacggat tgttatagac acagtatctt
    18961 tttctgttgc cggtgggatc acaacctgaa cacgttctcc acccggaagc gtggcggaac
    19021 gcaggggata ttcaggagtc acagaaccgc cgtcatgaaa atcagccagt gtggatgcaa
    19081 aagaaagaca atcactgtaa ctcatctttt gttcatacca ttgccacttt cccctgacct
    19141 ttataaatat ttctcctggt cggttaacag cgatttccgt gacaccctca atctcattca
    19201 gccagtgata aaaataatcg ttgaccacat cataaatcag atgtctgttt tcgttattca
    19261 cattaaccac ctttcatttt cagtttataa atgcctgaaa aatccagatc ctgtccgaca
    19321 atcagagtaa taatttcgcc ctgattttta taaagcgttg gcgggatatt cacactatta
    19381 gaaaatgctt cgcgtgctat atcagcaaaa gcctgtcgac tgttcgctgt atagtccgtc
    19441 tgactgtccc tgttattctg agcaatacca ctggccgcct gacttaaatc cggtatcatc
    19501 ccgaccatca tcgcccccag aaaacgctca ccaaaatgcg tgtcaatcca tcctgaagcc
    19561 ccggcttcgc ctaacgctcc agccgcctgt gagtcaatca ggggaatatc aataaaaggc
    19621 ttactgcgag tacgtagctt gtaagccata acaaacacac gcccttgtcc atgatttaaa
    19681 gacccggcct tatacatcag ttttgcggcg gttcctcttt cgataagttt tacattaccg
    19741 ctggcgctgt atatatcgct gttgaccgta cattccagtt tccccgccag gtcagaaaca
    19801 aaacgcctgt ccagtgaaca gggaattgat gtcccttccg ggataaacaa atttgggtca
    19861 tatggaagtt tcgttatttt cgccagtggc gcagattctg tagtctgtgc ggttgctttt
    19921 gcttcatcct ttttatcgct ttctggctca ctggccgcag tatgtgaaac tgacgttccc
    19981 gctgaactgc tgctgtttcc tgcctggctg ccatcaagag aaacatcaag tgcacggctg
    20041 aagctctgct gtttattttc cggcggttca gtcttttcag aagaaatgac tttttcttcc
    20101 tctggtttct ctgttttttt ctgtgcggta ttaaaaggat cgatatcttc gctcagtccg
    20161 gtctgacgtt tagccgctcc ggttgcaagc ggctgacttg cgggtttctc atcccctgac
    20221 gacacagaac ggataatgga cgggatataa taaacagaaa caccggcagc aagcagaaga
    20281 aaacccacga cgaggataat catcccttta cgtgactttt taagtttttc aataccaagc
    20341 tgcaatgctg gcttgccagg ctcttcttcc ggagtcttcc cggcctgttc cagttctttc
    20401 tgtctgcgtt cccgtagctg ctgttcaatt tcggttgcag tcgggatttt attttcctgt
    20461 tcagtcactg gatcacctct ttcttaacat ccggggatac cgtatctccg gctggtaaac
    20521 gtacttttcc gaagccctgg ttctcaatcc ccaccacctg ctcaccaaga cgtaaaacaa
    20581 aacgcttatc aaccggtacg ccaacagccg taaaactccc gctctgttta atcacaggat
    20641 tggtaagagt ctcctgcata ccgttcatca caaagacgct gggaattttc tttaacggac
    20701 tgaagccgaa ccaggtataa cgaccatcgt catatgcata atcagggctg atatcctggc
    20761 tgccttcagc aacccgcttc cagtactgcc agttacgggg cgatttcgca ttttccaggg
    20821 aacggttgat tgcctgttcc tccaggcgtc tggcaagagc ctctgtgcgt ttcttctcaa
    20881 tttcggcctg ttccttccgg cgttcctgcg gatactggta attcaccaca aacgcaattt
    20941 tctccggctg ccggaatgtc cgagcgttca gctccatgct gtaattacgc ttcgtggtgc
    21001 gaacaaacaa attcgttcgc cagcgttcaa gctcattttc cgggtcaaga gca
//
