LOCUS       CP083493.1             16074 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CP083493.1 Escherichia coli strain elppa8 plasmid unnamed2, complete
            sequence.
ACCESSION   CP083493
VERSION     CP083493.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:00:02
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 80134
            Orig. end    :: 96208
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16074
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[14000:15725]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..15725
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     cand_cluster    1..16074
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16074
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="2"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             651..1553
                     /locus_tag="ctg1_84"
                     /transl_table=11
                     /translation="MSIKNIKRIITAWKPSTFETYKKTFEKYGGSVNMHPDVVSYFMIH
                     HDWKFDFFHYEKDGDIKGSYFLCNGKQIGIMARRSYPLSSDEVLIPFSPHARCFFPDKT
                     NKLSIINKQNIINATWKIARKKQNCIIKESFSPKFEKTRRNEIQRFIRNGGEIKCISQL
                     SDKEISSSYISLFHSRFGGTLPCYEYDNLLMFISHLRELMFGHVLFWDNKPCAIDIVLK
                     SESSCNVYYDVPNGAVLNDENCMKLSPGSVLMWLNIDKARRYCQDNNKKMIYSIGAFRP
                     EWKYKLLWSVPCKVGKCLC"
     CDS             2236..2976
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 87.8; E-value: 1.9e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg1_85"
                     /transl_table=11
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAYL
                     LAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLNGVRPFVRILSEKVR
                     ARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAVRRA
                     EADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALVGHRDPRSMEVYTRVFALDMAA
                     TLAVPFTGDGRDAAEILRTLPPLR"
     CDS             3066..3185
                     /locus_tag="ctg1_86"
                     /transl_table=11
                     /translation="MFYEGSNASGSGYGITYVRDRQMAAQLQTALQETEYKLQ"
     CDS             complement(3261..4238)
                     /locus_tag="ctg1_87"
                     /transl_table=11
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTL
                     SRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELP
                     FVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYD
                     TERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISL
                     ARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPN
                     DESKENPLQPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     CDS             complement(4647..4943)
                     /locus_tag="ctg1_88"
                     /transl_table=11
                     /translation="MLGGADNPNGELPSYITGADTCSLYTQSLALKHTYEVYFGYDRTL
                     RKYGRFRQKLPVKTDIRKNSARRRPVTGRSPRTGEEAQCICSYREQVRPEALS"
     CDS             4984..5340
                     /locus_tag="ctg1_89"
                     /transl_table=11
                     /translation="MLSREDFYMIKQMRQQGAYIVDIAAQIGCSERTVRRYLKYPEPPA
                     RKTRHKMVKLKPFMDYIDMRLAENVWNSEVIFAEIKAMGYTGGRSMLRYYIQPKRKMRP
                     SKRTRRELPVKRET"
     CDS             5736..5987
                     /locus_tag="ctg1_90"
                     /transl_table=11
                     /translation="MKAGVMLADFTPSGIAQPGLFDEIQPRKNSEKLMKTLDELNQSGK
                     GKVWFAGRGTAPEWQMKREMLSQCYTTKWRDIPLARLG"
     CDS             complement(6167..6544)
                     /locus_tag="ctg1_91"
                     /transl_table=11
                     /translation="MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLM
                     SLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSF
                     SKSVELHDKVIGHYLNIKHYQ"
     CDS             complement(6589..6864)
                     /locus_tag="ctg1_92"
                     /transl_table=11
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDIVMNGVGCRVTARIMGVGLNTILRHLKNSGRSR"
     CDS             7220..8134
                     /gene_functions="transport (smcogs) SMCOG1252:cation ABC
                     transporter, periplasmic (Score: 310.5; E-value: 1.8e-94)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_93"
                     /transl_table=11
                     /translation="MLSIKKVTMLLGCLVLTCSIAFQASAAEKFKVITTFTIIADMAKN
                     VAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMNLELWFQRFYQHLNGVP
                     EVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDAFIKYDPANAQTYQRNA
                     DTYKAKITQTLAPLRKQIAELPENQRWMVTSEGAFSYLARDLGLKELYLWPINADQQGT
                     PQQVRKVVDIVKKNHIPAVFSESTISDKPARQVARETGAHYGGVLYVDSLSTENGPVPT
                     YIDLLKVTTSTLVQGIKAGKREK"
     CDS             8134..8961
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 180.8; E-value:
                     5.5e-55)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_94"
                     /transl_table=11
                     /translation="MMQSAGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSG
                     KSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLVAYVPQSEEVDWSFPVLVEDVVMMG
                     RYGHMGMLRIAKKRDRQIVTDALERVDMVDFRHRQIGELSGGQKKRVFLARAIAQQGDV
                     ILLDEPFTGVDVKTEAKIISLLRELRAEGKTMLVSTHNLGSVTTFCDYTVMVKGTVLAS
                     GPTDTTFTAENLELAFSGVLRHVTLNGSEESIITDDERPFVAHRPSAVQREER"
     CDS             8958..9815
                     /gene_functions="other (smcogs) SMCOG1245:ABC transporter
                     protein, integral membrane (Score: 302; E-value: 6.2e-92)"
                     /gene_kind="other"
                     /locus_tag="ctg1_95"
                     /transl_table=11
                     /translation="MNVLLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDA
                     LSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSMLFLNQLTRLKEDAIIGLIFSSFFGL
                     GLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFFDEN
                     HARAIGLHPGRLKILFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLM
                     IAVTIGSVTSFLGAWVSYFLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRRAHKAL
                     EDRS"
     CDS             9812..10669
                     /gene_functions="other (smcogs) SMCOG1245:ABC transporter
                     protein, integral membrane (Score: 293.7; E-value:
                     2.1e-89)"
                     /gene_kind="other"
                     /locus_tag="ctg1_96"
                     /transl_table=11
                     /translation="MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKSWALMGD
                     AMSHAVFPGIVLAWILGLPLATGAFVAGVFCAVATGYLKDNSRIKQDTVMGIVFSGMFA
                     AGLILYIAVKPDVHLDHILFGDMLGITIGDIIQTVIIAGLVTLVISVKWRDFLLFSFDY
                     QQAQASGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRFHIAL
                     LLATGISILVSMTGVWLSFFIDSAPAPTIVVLFAVMFIMTFTVTSINARTKENAEPRDL
                     LSSD"
     CDS             11137..11571
                     /locus_tag="ctg1_97"
                     /transl_table=11
                     /translation="MIFLPLTVAEDDWAGWKILHGALGEQIELVGDDLFVTNVKYIQRG
                     IDENLANSALIKLNQIGSLSETFDAVQLCHDNNWGTFISHRSGETVDSFIADMTVAMRA
                     GHLKTGAPCRGERIEKYNQLMRIEDELGSSAQFAGKSAFK"
     CDS             11625..11840
                     /locus_tag="ctg1_98"
                     /transl_table=11
                     /translation="MKAHVFVISMLTGIVVTYAVLLLGCLFIDKTLPTVDVVILSLVVG
                     ASAQQLSRVLMSINRTFPYLACSQRI"
     CDS             11912..12292
                     /locus_tag="ctg1_99"
                     /transl_table=11
                     /translation="MIKSLFAVIIGGSVGCTLRWLLSTRFNSLFPNLPPGTLVVNLLAG
                     LIIGTALAYFLRQPHLDPFWKLMITTGLCGGLSTFSTFSVEVFALLQAGNYIWALTSVL
                     VHVIGSLIMTALGFFIITILFA"
     CDS             complement(12672..13865)
                     /locus_tag="ctg1_100"
                     /transl_table=11
                     /translation="MSSKIEDTPQKTLSCWLLAFSAGLLGIGQNGLLVVLPVLVIQTNL
                     SLSVWAALLMLGSMLFLPSSPWWGKQISLTGSKTVVLWALGGYGVSFTLLGLGSVLMAT
                     GAVTTAVGLGILIIARIVYGLTVSAMVPACQVWALQRAGEGNRMVALATISSGLSCGRL
                     FGPLCAAAMLVIHPLAPVWMLMAAPVWAVVMLLRLPGTPPQPTPERKSVSLKRDCLPYL
                     LCAMLLAAAMSMMQLGLSPALTRQFDTDTTTISQQVAWLLGLSAIAALIAQFVVLRPQR
                     LTPVALLLSAGVLMSSGLAIMLTEQLWLFYLGCAVLSFGAALATPAYQLLLNDKLAGGA
                     GAGWLAASHTLGYGLCALLVPLASKTGVSIALIVTALFAAVLFTIVSACIWHYRTIK"
     CDS             14001..15725
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_101"
                     /sec_met_domain="IucA_IucC (E-value: 1.2e-62, bitscore:
                     204.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDEQ
                     KSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCET
                     FHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFNRQE
                     AERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLF
                     PLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSV
                     RLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDGWAGLRDLNGNIMQ
                     ESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAW
                     VDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATEW
                     LDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAE
                     VRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV"
     CDS             15726..16073
                     /locus_tag="ctg1_102"
                     /transl_table=11
                     /translation="MSGANIVHSGYGLRCEKLDKPLNLGWGLDNSAVLHWPGELPTGWL
                     CDALDQIFIAAPQLSAVVLPWSEWCEEPQALTLFGQVQSDIIHRSAFWQLPLWLSSPAN
                     RASGKMVFDAER"
ORIGIN
        1 cagtgtcctg atttaccttt gttggttgcc cgaccatcaa ttattgttgg ccacagtcgt
       61 ttagggtgct taccttcaac cagtattttc tgggtattca gaatggggtt aatgttgcaa
      121 aaatttatgt gctctctgga tgataaaata gatgttatcc ctgtagatta ttgtgctgat
      181 gcattgctaa tgttgcttga aagctcgtta attaatggtg agattgttca tatatcagca
      241 ggtaaagaaa gtagtgtgac gttctctgct attgacgaag ctgtagcccg tgctttgaac
      301 tgtgatcctg ttggagacag atatactaaa gtcagttatg acatactggc aatgagccgt
      361 catgatttta aaaatatttt tggtccctgt aacgaacgcc ttatgttaaa agccattcgt
      421 ttatatggag cgttcagtat gctcaatgtt tgtttcagta acgacaagct actgagtatc
      481 ggaatgccta aaccgccaaa gtttactgat tatattaaat actgtataga aacgacaaaa
      541 cacctttcaa ttcaacaaca aatggaagtt gattttaaat aatatttatc ataatcagaa
      601 ttattgttgg tgttgcactc ataatatata aaaacgccga ggatatgact ttgtcaatta
      661 aaaatataaa gcgcattatt acggcctgga aaccatctac attcgaaacg tacaaaaaaa
      721 cttttgaaaa atacggtggt agtgtaaaca tgcatccgga tgttgtttca tactttatga
      781 tacatcatga ctggaagttt gatttttttc actatgaaaa agatggtgat atcaaaggct
      841 catattttct gtgcaatgga aaacaaattg ggataatggc aagaaggtct tatcctcttt
      901 catctgatga ggtattaatt cctttttccc cacatgcaag atgttttttt ccggataaaa
      961 ctaataaatt atcaattata aataaacaaa atattatcaa tgcaacatgg aaaatagcca
     1021 gaaaaaaaca aaattgtatt ataaaggaat ctttttcacc taaatttgaa aaaactcgcc
     1081 gaaatgaaat ccagagattt atcaggaatg gcggagagat taagtgtata agccagttat
     1141 ccgataaaga aatatccagc tcttatatat cactttttca ttcccggttt ggaggtaccc
     1201 taccttgcta cgaatatgat aatctgttaa tgtttatttc tcacttacga gaacttatgt
     1261 ttggccatgt gctattctgg gataataaac cgtgtgctat tgatatagta ctgaaatctg
     1321 aaagctcatg taatgtttat tatgacgttc caaatggtgc agttctgaat gatgagaatt
     1381 gcatgaaact aagtccggga agtgtcctta tgtggctgaa tatagataaa gcgcgaaggt
     1441 attgtcagga taataataaa aagatgatat attctatcgg tgcattcaga cctgaatgga
     1501 aatataaact actatggtct gttccctgta aggttggtaa atgcttatgt tagaatatgt
     1561 ataaaggtaa gtaactatat aagagcgtcc agtctgcaaa tactcctcta aacatggagg
     1621 agtagattta taatatcata acatttacta aatcgtttta cattaatttc aaatttgaaa
     1681 ttaatgtatt ttgataacta tatatttttg attccgaaaa cagacatttc tttctttgag
     1741 tcagggctta cactcaaaat attaatattg tttgtgtgaa gacatattat tcaataacga
     1801 tggtgagaaa tatctgtact ttttcgcata atctaaccat ttacttaatt gttcattctg
     1861 tgaacagaat ctgtttgtta tgtatcaggt tgatgatgtg attaagcagt ctgaaaccag
     1921 aggaatatgg agtcagaaat tttcagttgt cttttaaggg cgtctgcagg attttttctc
     1981 cgtttctgcc tgtcctggca ttaccccaat tctcccaaaa acggtaaacc agccctcagc
     2041 ccgcaccatg actggcttaa gacgggatcc cagcggcaaa atgcgccttt atgtatttgg
     2101 ttttacccgc aataatgcgt gataatcaaa caaaaggatc cgcgcgctgc gatttattgt
     2161 cgtggaagga tccgggcgtt caggtcagaa tacctgtatc cataaacagt gcgtgtgcta
     2221 cgtgaaaaat aactcatgaa caatgtcatt cccctgcaga attcacctga acgcgtctcc
     2281 ctgttaccca ttgcgccggg ggtggatttt gcaacagcgc tctccctgag aagaatggcc
     2341 acttccacgg gggccacacc ggcctacctg ctggccccgg aagtgagtgc ccttctcttc
     2401 tatatgccgg atcagcgtca ccatatgctg ttcgccaccc tctggaatac cggaatgcgt
     2461 attggcgaag cccggatgct gacgccggaa tcatttgacc tgaatggagt aagaccgttt
     2521 gtgcggatcc tgtccgaaaa agtgcgtgcg cgacgcggac gcccgccaaa agatgaagtg
     2581 cgcctggttc cgctgacaga tataagctat gtcaggcaga tggaaagctg gatgatcacc
     2641 acccggcccc gtcgtcgtga accattatgg gccgtgaccg acgaaaccat gcgcaactgg
     2701 ctgaagcagg ctgtcagacg ggccgaagct gacggagtac acttttcgat tccggtcaca
     2761 ccacacacct tccggcacag ctatatcatg cacatgctct atcaccgcca gccccggaaa
     2821 gtcatccagg cactggttgg tcacagggat ccacgttcga tggaggttta taccagagtg
     2881 tttgcactgg atatggctgc cacgctggca gtgcctttca caggtgacgg gcgggatgct
     2941 gcggagatcc tgcgtacact gcctcccctg aggtgacggc atacgcgctt ccttatataa
     3001 gctgtggtca gcagaacaga cataacataa gctggagcat gtatataagc tgtagtgagt
     3061 aagtcatgtt ttatgaaggg agcaatgcct caggatcagg ttacgggatc acttacgtaa
     3121 gggacaggca gatggcagct cagctacaga cagcactgca ggaaacagaa tataaactgc
     3181 agtgagcaga ccactcactg cgccggttaa tataagctgt agtcagtaaa ggagcgctct
     3241 tcactgacta cagtttatgt tcagcgggat ttgaagagtt tttccaggtc atccagcgtg
     3301 atgcccagtt tctcaagcag ggcaagcttc tccgccatct ccggactgac tttttccgca
     3361 ggtgaaggtt gcaacggatt ttccttactc tcgtcattcg gcgcttttaa ccggggacgc
     3421 cggtagtgaa tacagaagaa ttttgtccgc ccccgctgga tctccgtgta atcaagatat
     3481 ccaatctcgc gcaactgctc cattgcccgt ctgaccgtct ggttctggga aaatacagga
     3541 gacttcagat tgaggcgtgc acgcagccgc gccagcgata tcggtgccgg atcccggggc
     3601 aggctctcta taaaggtgta gagtgcctgg gcggactccc gtcgcttcag ggcattaatc
     3661 gccttaagct ggagaaggac ttttctgtca aactggtaca gttcaaacag gcggggatcg
     3721 gcctgtaact gcacaatatc ccgctcagta tcgtagtaag ctgactgtac cagatgggtg
     3781 atatattccc gggtgtgctt ctcatcggta cgggaaaacg aaatcacggt accggcaatg
     3841 cgcttcaggg aagggctgat gcgctcacgc agcctgcggg atgactggct tgaaggtata
     3901 ccacacagtt ttgcaaactc aacaaaaggc agttcaactt tgtcaccaat cacgttatgg
     3961 cgggcaaagg aatgaatgat ccccacccag gtcttgaaat cattatccat atccaggcgg
     4021 gggccggtga tctcaacctt atcgaatccc tcagcacggg ccagggaaag acgtgtcagc
     4081 tcttccgtgg catcagtacg tgacagtgta ttttttttac tgttcttcag tgatttaagg
     4141 gtcggtacaa aaacgcccag acgcatcagc gccacaggtt gtacggtgtt gttattgttt
     4201 ggtgtcagtg tcaccagctc accggaggac ttatccacct cgccgaacag ttttttgatg
     4261 tctgaatttt cgttttccag aaagcctcca gcctgtggac agtaaaagaa taaacagaaa
     4321 atcgtgtgtc agaactccgc taactgactg aagaaaaacc tgcagcctgt atttaacaac
     4381 tgagtctggc atactgacca tagtttatgt cattaactta cttcagtata tggattactg
     4441 aatacagctt atcattagca tgttacagtt tatcagtaac atgccacagc ttatgtgatc
     4501 gtggtcccgg cccatgagtg acaaggtttg cagcgatatg gggatcttta atggatcctt
     4561 tgttgatcat tcatggatct gtttactgga tcgggcctcc ggatatgtgg ataaatcatt
     4621 ccagaaggac agcgcacaca accgttttat gaaagggctt cagggcgtac ctgctccctg
     4681 taactacaga tacattgcgc ttcctcgccg gttcgcgggc ttcgcccggt caccggtctg
     4741 cggcgagcac tgttttttct gatgtctgtc tttacaggta atttttgacg gaatctgccg
     4801 tacttcctga gcgtacggtc atatccgaag tacacttcat atgtgtgttt caatgccagg
     4861 gattgtgtat acaaactaca ggtgtcagcg ccagtgatat aagacggtaa ttcaccattt
     4921 ggattgtccg ctccacccaa catgttgttt ccttaaggtt ctcacaccag aaaggacatc
     4981 aacatgctga gcagagagga cttttacatg ataaagcaaa tgcgccagca gggcgcgtac
     5041 attgtcgata ttgcggctca gattggttgc tctgaacgga cggtcagacg ctacctcaaa
     5101 taccctgaac cgccagccag aaagacccgc cacaaaatgg ttaagctgaa accgtttatg
     5161 gattacatcg acatgcgcct ggcagagaat gtctggaata gcgaggttat cttcgcggag
     5221 attaaggcaa tgggttatac gggcggacgt tccatgctgc gttactacat ccagcccaaa
     5281 cgtaaaatgc gtccgtcaaa aagaacaagg agagagttac cggttaaaag agaaacgtaa
     5341 agctggagtg ctgaccaaaa acacaacgcc aatcagtgat gatgaaatgg tgcaaagcgg
     5401 acagcatcag taacgaaagt atttagcggg catgaaaatg gcaaataacg gtcaaacatc
     5461 gtggcgttga catagtcgca gttttggtga acgaatcaca gacaaagatg ccatgcacca
     5521 ggctgttgtt cagtatgcag agcgggccgc agagaaacta cgtggggagc gtcagtattg
     5581 ccggcaggtg acgacatttg tacggacatc cccctgaacc ctgttacagc aatgccgctg
     5641 tggaaaagct ttcattgccc acacaggaca gccgggacat tattgccgcc gcatgcagag
     5701 ccttaaacca tgtctggcgt gaagggtacc gctatatgaa ggcaggagtc atgctggctg
     5761 atttcacacc atcgggtata gcgcagccgg gattatttga tgaaatccag ccccgtaaaa
     5821 acagtgaaaa gttaatgaaa acactcgatg aactgaacca gtcgggaaaa gggaaagtgt
     5881 ggtttgcggg gcgaggaacc gcccctgaat ggcaaatgaa acgggaaatg ttgagtcagt
     5941 gttatacaac taaatggcga gatattcccc tggccaggct gggttagttc agtcatctcc
     6001 gaacatattt tcagcgtttc ttctggtctg gtcttcaccg tcatttctcg acagactctg
     6061 ctctgtaagg ggagtactgc aatccacaga cgtatggaga ccagattgtt tttccagtaa
     6121 ttcaatcaat ttcttttcaa ccgaaaaagc aggtaatgac tccaacttat tgatagtgtt
     6181 ttatgttcag ataatgcccg atgactttgt catgcagctc caccgatttt gagaacgaca
     6241 gcgacttccg tcccagccgt gccaggtgct gcctcagatt caggttatgc cgctcaattc
     6301 gctgcgtata tcgcttgctg attacgtgca gctttccctt caggcgggat tcatacagcg
     6361 gccagccatc cgtcatccat atcaccacgt caaagggtga cagcaggctc ataagacgcc
     6421 ccagcgtcgc catagtgcgt tcaccgaata cgtgcgcaac aaccgtcttc cggagactgt
     6481 catacgcgta aaacagccag cgctggcgcg atttagcccc gacatagccc cactgttcgt
     6541 ccatttccgc gcagacgatg acgtcactgc ccggctgtat gcgcgaggtt accgactgcg
     6601 gcctgagttt tttaagtgac gtaaaatcgt gttgaggcca acgcccataa tgcgggcagt
     6661 tacccggcat ccaacgccat tcatgactat atcaatgatt ttctggtgcg taccgggttg
     6721 agaagcggtg taagtgaact gcagttgcca tgttttacgg cagtgagagc agagatagcg
     6781 ctgatgtccg gcggtgcttt tgccgttacg caccaccccg tcagtagctg aacaggaggg
     6841 acagctgata gaaacagaag ccactggagc acctcaaaaa caccatcata cactaaatca
     6901 gtaagttggc agcatcaccg atcccttcat ttagtgactg cccctgggtt tttcatgctc
     6961 tcctgcgtcc tagagaactt gccaataacc tacattattt ttgctttgcc attaccaatc
     7021 gtcctgaaca agttcatttt aaagccaaag cgctgcccaa cttttatcct caataccaca
     7081 tcgtcagcag gaaataacct aatccctgtg ttgggatctt ataatcgcta atgataatta
     7141 tttacatttt atagcttctg ctataaaaca tagtagttgc tatgtttatt ctaattttgc
     7201 tcactatagg tactaaatca tgctctcaat aaaaaaagta accatgctct tggggtgcct
     7261 agtcctcacc tgctcgatag catttcaggc gagtgcagct gaaaaattca aggtcattac
     7321 aacttttacc atcatcgcag atatggccaa aaacgtggct ggagatgctg cagaagtctc
     7381 atccataacc aagcctggtg cagaaattca tgagtatcag cctacccctg gcgatattaa
     7441 acgtgcgcag ggggcacaac tgattctcgc caatggtatg aatctggaat tgtggttcca
     7501 acgcttttac cagcatctca atggggttcc agaagtaatt gtctcttcgg gtgtgacgcc
     7561 agtagggatc accgaagggc cctatgaggg caaacctaac ccccatgcct ggatgtcgcc
     7621 agataatgct ctgatttacg tcgataatat tcgtgatgcg tttataaaat acgatccggc
     7681 aaatgcacaa acctaccaac gtaatgccga tacttataaa gccaagatta cccaaaccct
     7741 tgcccccctg cgtaagcaga ttgcggaact ccctgagaat cagcgatgga tggtcaccag
     7801 tgaaggggct ttttcttatc tcgcacgcga tttggggcta aaagagcttt atctgtggcc
     7861 gattaatgcc gatcaacaag gaacaccgca gcaggtacgt aaggttgttg atatagttaa
     7921 gaaaaatcat atcccggcag tctttagcga gagtacgatt tccgataaac cagcgcgtca
     7981 ggttgcgcgt gaaaccggcg cgcactacgg tggtgtgctc tatgtcgatt ccctgagcac
     8041 agaaaacggc ccggtaccta cgtatatcga ccttctgaag gttactacca gtacgctggt
     8101 acagggaatt aaagccggaa aaagggagaa ataatgatgc aatctgcagg cattgtcgtt
     8161 aatgatgtta ctgtcacctg gcgtaacggg cacacagcac tgcgcgatgc atccttcaca
     8221 gtaccaggcg gatctattgc cgctctggtt ggggtaaacg gttccggaaa atcgacgttg
     8281 tttaaagcga ttatgggatt tgtgcgtctg accagcggga agatatctgt tctgggtatt
     8341 cccacacgac aggcgctaca gaaaaacctg gttgcctacg tccctcagtc agaagaggtt
     8401 gactggtcat ttcctgtact ggtggaagat gtggtgatga tgggccgcta tgggcatatg
     8461 ggtatgttgc gtatcgccaa aaagagggat cgtcagattg tcaccgatgc gctggaacgt
     8521 gtcgatatgg tggattttcg ccatcgacaa atcggcgagc tttccggtgg acaaaagaaa
     8581 cgcgtctttc tggcgagagc gattgcacag cagggtgatg tgatcctgct ggatgaacct
     8641 tttaccggcg ttgatgtgaa aaccgaagcg aaaatcatca gcctgttgag ggagttacgc
     8701 gcggaaggca aaacgatgct tgtctcaacg cacaatctcg gatccgtcac gacattttgc
     8761 gattatacgg tcatggtcaa aggcaccgtc ctggcaagcg ggccgacaga caccactttt
     8821 acagccgaga acctggagct ggcttttagc ggcgtactgc gccatgtcac acttaacggc
     8881 tcggaagaaa gcattattac tgacgatgaa cgcccttttg tggcacatcg accgtcagcg
     8941 gtgcagaggg aagaaagatg aacgtgctac tggaaccctt cagctatgaa tatatgctca
     9001 atgcgatgtg ggtctcggcg atggtcggcg gtctctgcgc tttcctgtca tgctatctga
     9061 tgctaaaagg ctggtcgctg attggcgatg cgctgtcgca ctctattgtc ccgggtgttg
     9121 cgggggcata tatgctgggg cttccgtttt ctctgggagc cttcttttcc ggcggactgg
     9181 cagcgggcag catgctgttt cttaaccaac tcactcgctt aaaagaagat gccatcatcg
     9241 gcctgatctt ctcgtccttt tttggcctgg ggctgtttat ggtgtcattg aacccgacat
     9301 ccgtgaacat tcagaccatc gtcctgggca atattctggc aatcgatccg gcggatatcc
     9361 tgcaactcac tatcattggc attctctcga tcatcgtgct ttttttcaaa tggaaagatc
     9421 ttatggtgac ctttttcgac gagaatcacg cccgtgctat tggattgcat ccgggcagat
     9481 taaaaatcct cttcttcacc ctgctgtcgg tttcgaccgt tgcggcgctg caaacggttg
     9541 gtgcctttct ggtgatctgt ctggtggtga ctcccggtgc aacagcatgg ttgttaaccg
     9601 atcgttttcc ccgcctgctc atgattgctg taactattgg cagtgtgacc agtttcctcg
     9661 gcgcgtgggt cagttacttt ctggacggcg cgacaggtgg aatcatcgtg gtggcgcaga
     9721 cactgctgtt tcttttagca tttgtctttg cgcccaccca tgggcttttg gcaaatcgtc
     9781 ggcgtgcgca taaagcgctg gaggatcgct catgatggca ttattactgg agccactgca
     9841 gttcaccttt atgagtcacg cactgctgat ttcactggta gtttccatac cctgtgcgct
     9901 gctgtcggtc tttctggtcc tgaaaagttg ggcactgatg ggtgacgcga tgagtcatgc
     9961 ggtttttcct ggcatcgtgc ttgcctggat tctggggtta cctctggcta caggggcatt
    10021 cgtcgccgga gtattctgtg cggtggcgac gggatacctg aaagacaaca gccgaatcaa
    10081 gcaagataca gtgatgggga ttgttttttc tggcatgttt gccgcaggtc tgatcttgta
    10141 tattgcagtc aaaccagacg tacatcttga tcatattctt ttcggcgaca tgctcgggat
    10201 aaccatcggc gatataatcc agacggtgat tattgccgga ctggttacac ttgttattag
    10261 cgtaaaatgg cgggattttt tgctgttcag ctttgattat caacaggcgc aggcaagcgg
    10321 tttgcatacg agatggctgc attatgggct gctgtgcatg gtctccctga ccattgtggc
    10381 gacgctgaaa gcggtaggta tcattctctc tatttctctt ctcattgcgc ctggtgccat
    10441 tgcggtactc ctgacacaac gctttcatat tgcgctcctg ctggcgactg gcatatcgat
    10501 attggtctca atgactggtg tctggctgtc cttttttatc gacagcgcgc cagctccgac
    10561 aattgttgtc ttattcgcgg tcatgttcat catgacgttt accgttacca gcatcaacgc
    10621 acgcacaaag gaaaatgccg aaccacggga tttgttatca tccgattagc agaacactcg
    10681 gccagcaaca tccgcttatt ggcgatgcgc ttgaacgaat aatgcacaga cttatgattc
    10741 tgataagttt tgttgccaga gagttgctgc ggactggata gcaagtaatg tcgattctca
    10801 ggggtagcaa acagcgcagt aaaatgaggg aagtagtggc aaaacataga gaaaattggg
    10861 gggcgagggc cagtgatgta aaaaaccacg ctaagagttt aattaattgt ttgtattgaa
    10921 gtttaatgat cttaactcac ccttaagaat atcttccggt aacgaagacg tataatgccc
    10981 cagcatattt atatggctat gtatcagcag cgataatctt gccggatgct actcctcagg
    11041 agtttctccc gatttgcgaa gatgtgacaa cgcctcctgc atgtaaagtg tgtttcacag
    11101 cacaaccgca ttggtcacca gccccagagc acctagttga tcttcctgcc cttaacggta
    11161 gctgaagatg actgggctgg atggaaaatc ctgcatggtg cattgggaga gcagatagaa
    11221 ttggttggcg acgatctgtt tgtgaccaac gtaaagtata ttcagcgcgg cattgacgaa
    11281 aaccttgcca attcagcatt gattaaactc aaccagattg gttccctgag tgaaaccttt
    11341 gatgcggtac aactttgcca tgacaacaac tggggcacct ttatctcaca ccgcagtggt
    11401 gagacagtgg acagctttat cgccgatatg acagttgcaa tgcgcgcagg tcatctcaaa
    11461 acgggagctc catgccgggg tgagcgtatt gaaaaatata accagcttat gagaattgag
    11521 gatgaactgg gttcatcggc gcaatttgct ggaaagtctg cctttaaatg acattattgt
    11581 gccaatcccc caggcttaca cgtcggggtt attctggagg aatgatgaaa gctcacgttt
    11641 ttgttatttc tatgcttact ggcattgtcg tcacctatgc cgtgttactt cttggttgct
    11701 tgttcatcga taaaacgctc cccactgtag atgttgtcat tctgtcactt gtcgtggggg
    11761 cttctgctca gcaattgtcg agggtattaa tgtcaataaa tagaaccttc ccttatcttg
    11821 catgtagtca aaggatataa attaacaata tcagtcaaat gagaacatat tctgatattg
    11881 ttacgataaa aaattatttt atgaggggta catgattaaa tcactttttg ccgtcattat
    11941 cggcggttct gttggatgta ctctgcgctg gttactgtcc acacgcttta acagtctttt
    12001 tccaaatcta cctccaggta cactggtggt gaacctcctt gccgggttaa ttattggtac
    12061 tgcgttggcg tactttttac gacaaccaca ccttgatcct ttttggaaat taatgataac
    12121 aacgggactt tgtggaggtc tgagtacttt ctctacattt tctgttgaag tattcgcatt
    12181 actccaggcg ggaaattata tatgggcttt gacgtctgta cttgttcacg tcattggctc
    12241 cctcatcatg acagctttag gcttttttat cataaccata cttttcgcat gagaattcat
    12301 taacgttaca ggtttatcaa ctaatgtgac gcttaggata gaatttcgct ccatggtatg
    12361 cgtttgcagt cattacagtc tccatgacga ctgtaatgac tgcaaacgca ttacctgaca
    12421 tatcagtata aacaatgaat taacctcttg gcgtattttt tacatcactg gccctcaccc
    12481 cccaaaattc tctctgaaaa attgttgcgg ttaacgttgc caatgtatcc acccatttca
    12541 gaagacgatc tggcatcctg gtggcatgct gcgatgtgct tcaggtgagt gcactgggcg
    12601 gtcagcacag gcggtttcga cagcgaaatt gcacaggacg ttatgccggc tgtgagtaca
    12661 acatcatagc cttacttgat tgtacggtaa tgccaaatac atgcagacac tatggtaaat
    12721 aatacagcgg caaataatgc cgtcacaatc agcgcgattg agacacctgt tttcgacgcc
    12781 agtggcacca acaatgcgca cagcccatag ccaagtgtgt gactggccgc aagccagccc
    12841 gcgcctgcgc cgcctgccag cttatcattc agtaaaagtt gataagcggg tgttgccaga
    12901 gcggccccaa atgacagcac tgcacagccc aggtaaaaca accatagctg ttcagtgagc
    12961 atgatagcca gaccactact catcaacacc ccggcactca ggagcagagc cactggagtc
    13021 aggcgctgtg gacggagtac cacgaactgc gcgataagcg ctgctattgc ggacagcccc
    13081 aacaaccacg ccacctgttg gctaatagtg gtggtatcag tatcgaactg gcgagtaagg
    13141 gctggcgaaa gtccaagctg catcatgctc attgccgcag ccagtaacat tgcgcaaagc
    13201 agataaggca ggcaatcccg cttcaggctg acgctcttgc gctccggtgt gggctgtggt
    13261 ggtgtgccgg gcaaccgcag aagcatcacc acagcccaca ccggagctgc catcagcatc
    13321 cacactggcg ccagagggtg aatgaccaac attgccgccg cgcacagcgg cccgaatagc
    13381 ctgccgcagc tcaggccgga gctgatggtt gccagagcta ccatgcgatt cccttctccc
    13441 gctctctgca atgcccagac ctgacaggct ggcaccattg ctgacacggt cagaccgtag
    13501 acgatccggg cgatgattaa tattcccaac cccaccgctg ttgttacggc accggtagcc
    13561 atcagcacgc ttcccagccc aagcagggta aagcttacgc catatcctcc cagagcccac
    13621 agcaccacag tcttactgcc agtaagggaa atttgctttc cccaccatgg ggaagatggc
    13681 agaaacagca ttgagcccag catcagcagg gcagcccata cagacagact cagatttgtc
    13741 tgtatgacca gaacagggag tacaaccagc agaccgttct gtccgatacc gagaagaccg
    13801 gcactgaacg ccagtagcca gcaggacagg gttttttggg gcgtatcttc gatcttagat
    13861 gacattgtaa tgtttcaaca ccatgtatta attgtgttta tttgtaaaat taatttttct
    13921 gacaataaca tttctcattg ataatgagaa tcattattga cataattgtt attattttac
    13981 tgtgtaggag ctgtttgatt atgatcctgc cctctgaaaa atccgccaca gatgtggctg
    14041 cgcagtgctt cctgaatgcc ttgattcgtg aaaccaaaga ctggcaactg gcggaatacc
    14101 cgccagacga attgattatc ccgctggacg aacagaagtc gctccatttc agagtggctt
    14161 atttctcccc aacccagcat caccgctttg catttcctgc tcatctggtc acggcatcag
    14221 gcagttatcc tgtcgacttt accactctct cccggcttat tattgataag ctccggcatc
    14281 aactttttct gccagttccc ctctgcgaaa ctttccacca acgcgtgctg gaaagctacg
    14341 cccatacgca acagacaatt gatgcccgcc atgactgggc catcctgcgt gaaaaagcgt
    14401 tgaattttgg cgaggctgag caggcactgc tgacaggaca cgctttccac cctgcaccta
    14461 agtctcatga accgtttaac cgccaggaag ctgaacgata cctgcctgac atggcacctc
    14521 acttcccgct gcggtggttt tcggtggata aaacgcaaat cgctggtgaa agtctgcatc
    14581 ttaaccttca acagcggttg acgcgatttg ccgcagaaaa tgcgccccag ttactcaacg
    14641 aattaagtga caatcaatgg ctgttcccgc tgcacccgtg gcagggagaa tatcttttgc
    14701 agcaagtgtg gtgccaggca ctttttgcta aaggacttat cagagactta ggcgaggccg
    14761 gcacgtcgtg gctgccgacc acctcttccc gctccctcta ctgtgctacc agccgcgata
    14821 tgatcaagtt ctccctgagc gttcggctga ccaactccgt ccgtactctg tctgtgaaag
    14881 aggtggagcg aggaatgcgc ctggcacgtc tggcgcaaac cgacggctgg cagatgctac
    14941 aggcccgctt ccctactttc cgggtaatgc aggaggacgg ctgggccggg ctgcgcgatc
    15001 ttaacggcaa catcatgcag gaaagtttgt tttccctgcg tgaaaacctg ctgctggagc
    15061 agccgcaaag ccagaccaac gttctggttt ccctgactca ggccgcaccg gatggcggtg
    15121 attcgctgct ggtttcggcg gtaaaacgcc tgagcgatcg cctcggtatc actgtgcaac
    15181 aggccgccca cgcatgggtc gatgcttact gtcagcaggt gctgaagcct ctgtttacgg
    15241 ctgaagcgga ttacggcctg gtgctgctgg cgcatcagca aaatattctt gtgcagatgc
    15301 ttggggatct gccggtcgga tttatttacc gtgactgcca gggcagcgcg tttatgcctc
    15361 acgcgacaga gtggctcgat accattgacg aggcgcaggc ggaaaatatt ttcacccgtg
    15421 agcagttgct gcgctatttc ccttattacc tgctggttaa ctccactttt gccgtaactg
    15481 ctgcgctggg tgctgccggg ctggacagcg aagcgaatct gatggctcgt gtacgaacat
    15541 tgctggctga agtgcgtgac caggtgactc ataaaacctg tctcaactat gttctggaaa
    15601 gtccgtactg gaacgtaaaa ggtaactttt tctgttatct gaacgatcat aacgagaaca
    15661 ccatcgttga cccttcggtg atctattttg atttcgctaa cccgctgcag gctcaggagg
    15721 tctgaatgtc tggggcaaac attgttcaca gcggatatgg actgcgctgt gaaaaactcg
    15781 acaagcctct gaatcttggc tgggggctgg acaatagcgc ggtgttgcac tggcccgggg
    15841 agctgccaac agggtggctg tgcgacgcgc tggatcagat atttatcgcc gcaccacaac
    15901 tttcagcagt ggttcttccc tggtccgaat ggtgtgagga gccacaggcg ctgacgcttt
    15961 tcggacaggt acaaagcgac attatccatc gttccgcttt ctggcagtta ccgttatggc
    16021 tgagttctcc ggcaaaccgg gcctccggta aaatggtttt tgatgcagag cgtg
//
