LOCUS       CP067458.1             15271 bp    DNA              UNK 01-JAN-1980
DEFINITION  CP067458.1 Klebsiella pneumoniae strain ARLG-4884 plasmid pC877_4,
            complete sequence.
ACCESSION   CP067458
VERSION     CP067458.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 21:05:32
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..180
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
     CDS             complement(208..738)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
     protocluster    422..12107
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5421:7107]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5422..7107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    422..12107
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          422..12107
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(745..1476)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
     CDS             complement(1476..3440)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
     CDS             complement(4152..4280)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MEKRHLRGLAVLPHMLVPCLFTESVGNFACVRSARRSLTAGA"
     CDS             complement(5155..5412)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
     CDS             complement(5422..7107)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7"
                     /sec_met_domain="Cloacin (E-value: 2.1e-113, bitscore:
                     367.1, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
     CDS             complement(7843..8547)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
     CDS             complement(8559..8816)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDID
                     LLVTVTVRLDETTRRALINDLLETALLQIVGGDKLIIPFC"
     CDS             complement(8898..9503)
                     /gene_functions="resistance (resist) AAC6-Ib (Score: 433.7;
                     E-value: 3.3e-133)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     59.9; E-value: 5.4e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRS
                     HIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGW
                     WEEETDPGVRGIDQSLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAI
                     RCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"
     CDS             complement(9686..10243)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             10405..13410
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
     CDS             13487..13906
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
     CDS             14212..14475
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
     CDS             14465..14764
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
     CDS             complement(14826..15203)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
ORIGIN
        1 atgacaaaac aggaaaaaac agccctcaat atggctaaat ttattaagga gcagtcgctg
       61 ctattgctcg ataaactgaa tgagctggat atggataccc cggccgacat gtgcgagcgg
      121 ctacacgagg atgcggaaac actctggcag gtgatgcggg ataagctcgg ggaggaataa
      181 cagcaccggc atggccggtg ctggcattta ttttttgccg aacggccacc accggcgggc
      241 aggtttgtcc tccggcagtt caggtaccgg cacgttaaaa tagcggctgt tatattcccg
      301 catcagctcc gctttcagct tctcgttcac cgcgctttcc ccgtgccgct cactcaccac
      361 gtcaatcatc gcgttaatct gctccggtga gcacttcccg gcatcaacca cctgcacacc
      421 gttctcgatg gcgaaccgct ccaccttgcg atagaggtaa tcacacagct tcattcctgt
      481 gggtttgttc cgttcccatt gcggattttt accagtgaaa aagtacgtgg ctttttcgtc
      541 gctgttgagc cgctcgtcat acatcccgat ggatttcatc atcgccagat gctgggcccg
      601 gtcgacaaaa cagaaaacat acgccccggt ctgccaggcg agcaccacca tatcttccag
      661 atgctcgctg gtcggcatga tgcagcgctc gccgttccgg tcctccgcgt cttcaataaa
      721 taccatgtac agcgccataa tccctcactc cgttgtcata aatttaaagc acgcaaacaa
      781 ccgttcacga tccagctctg ccgttttgcg ggcctcgccg gtctgtgggt tcacgatttc
      841 atccaccgac aggattgccc gctgcaccct gacctgcgtc gcccggtccg ggcagatgta
      901 ccagatttca tcgatgccgt tagctttgcg gttgaacaga tacccggaca ccacttcctg
      961 ataccggcga cggctcttga cggtgcgctc cacctcaaac gccaccgttt taccgtccag
     1021 ctccgccagg gcgtccggca ctttcatgcc tttaagactc agacggtgca gaatgcgcca
     1081 gccggtggcc cctctggctt ccatatcaag gcgcagggat tgcacggcca gccggtgcgg
     1141 cagatgtgct gccgacaccc ttgacggctg aaacggaata acatccgcca gcggttcgtc
     1201 ctcgtcgaac gagaacgcca cgccatgcgg cgtcagcccc cacacgctga cctgacggcc
     1261 gtccaccgga tatttggtcc ggaccagcag ccctttcgcc accaggctgt cgaggaagcg
     1321 gtagaccggc tgcaccgccg caatccccag ccgccgcgca accagctccg ccgtggaaca
     1381 cagctcttcc cgcaaccagc gcagggtcag ccgggttttc tccgcgttcc gcgcctgtcg
     1441 tttcgcgtgg ctgacgttgt acagctccag cgccatcagt aaatccccgc aaaatcatca
     1501 tccgctttcg gcccgccgcc gtcggccggg ggccggaact ccgccagggg atcggttttc
     1561 gccagcaccg ggaaacgctg caacgggatt tcccggcgct caacccgcag cggactgctg
     1621 aacgccatcc gggccacacc cagcccggtc atgaccgcga acccgtccgg caggtgttgc
     1681 agggtgttca cgtcaaacag cggccgcgcc tccttctgga tgaagctgtc cccgctgata
     1741 tgctccacgt tccccgcctc ccggctggca cggcggcgct ccacgtccac cctgatttcc
     1801 ccggtctgcc ccgccgccca ctgcgcggac tccaggctgg ccgcccggta aaaccagcgg
     1861 atcggcgtgt tatccagtac cgtggttttc acaaattcag cgggcagatc ctgcccgcac
     1921 tgcccgaaat cgcccagcga ctggtgcgcg agcaacagat tgcagtcccg gctgcgcagc
     1981 gtccccagtg cgttcagtac atacttcgac agcagatatt taatttcatc gagcatcacg
     2041 ctgacgtgtg gccactcccg gaactcgtcc cgcgcaatga tgatttgcgc gcagcgggca
     2101 aacagcattt tttgcacacg gatcaccgcc tcgtcgtcca tcgagccgat aacgtacagg
     2161 cagccgccgc cgttgataat ccccgccaca tcgatgccac tgtccgtctg caggacgctc
     2221 aggtcagcga cgttttccag cctagtgatc aaccccttca cgtccttttt cagggcctcc
     2281 ggcagcgcgt acgccgccgc cagcacctgc tgaatgtttg ccccctgcgg aaactgctcc
     2341 gcaatcagct tcgccgcttt ctgctcgctg atgcggtagt ggtccgccac gtcgccggtc
     2401 tcgcccaggt taagcccggc aatcagcagg tttttcagcg cgtactggtc gagatcgcgg
     2461 aacagattca gctgcgccgg tttccccggc cgcagatcca gcagggtgaa gtccggacag
     2521 tgcgcccgga agacgtgcgg cgcccatgcg tcccctttgg ggtcgaagta caccaccgcg
     2581 tccccgaaat cgcgtacgca gcgaatgagc gcgttggtgg ccatcacgct cttgccgctc
     2641 ccgggcaggc cgaggatctg aatgttggtc ttgcgccagg tatcacgcgg aaccagcacc
     2701 ggcttgccct gctcatcctt acccagaaac accgcctgct cctgccgggc ctgctccgag
     2761 gaaaaatcgg ccagcgcatt aaccggtacc ggctccccga aatgcaggtg gcgcacgtcg
     2821 gtcatctctc ctgtccgctg gctgctgcgc cggctctcct gattcagttt cgcgttcacc
     2881 gcctcgtcag cagccgcaaa atgaccgtca agcagcagga acgccagcag ccgcgccaac
     2941 acaatcccga cagccagccc gcccgcgcac caggcaatcc cgaacaggtt agccggctgc
     3001 agcaggtaat aatctgcgtt tgcgtagagg tccggacgca ggacggtttc tccccagctc
     3061 tcgataaaca cggcgacaac cagccccccc agaagggcca gaccggccgc gccggtcagc
     3121 cagtacgcgt agttccagac atgtcgacgt gccctgacca tccgcccggg cgaatccagc
     3181 gaggccagca ccgaaaatgg cgctggccgt ttattatcgc gcttatagcg atcggcatac
     3241 tcccgtcgct ccttatgact cagccccaca aaacgcatcc gtccggccca aagttcagcc
     3301 agaccgaaaa acaggccgat aactaggaaa gccccggcca gaccgtaata ctcctggtac
     3361 agccagctga cccacggata aatctgccgg gccagctccg gaatgtgcca cttccaggca
     3421 agcgaatccg tattaaacat gttctctctc cttcagacga tggtttgccg gcgtgatgtg
     3481 cagcccccgc tgcacaagcc gcggacatgc cccaaggcat ggcggcggcg gtcacgtccg
     3541 tggtgattgc gttcagcttt caccacggag gccagcctct ttccgcccca tgcggaaaag
     3601 gcgcagcccc ggaggaacaa cgagcacgcc ccagcgtgtg agaggaaaag gcggcacccc
     3661 agtgcggtct tttccggtgt tccggccccc gtcagagttc gccatagcga gcggctgacc
     3721 acccgcaaaa tcaggagcag ctttgctgct tcgccaggtg cgtccagcac cgtggatttt
     3781 tgtgggtggt caggcgtgag cctgacgggg gccgggtgaa tttctggcgt ggccggcgtc
     3841 cagccggacg gagccagaaa gagggggaga gaccgtgcgt cggtggcgtc cagccagcgt
     3901 aagcagggga tatccccctg aggtcagcca cgccctcgcg gggatgacct gtatttctcc
     3961 gtaaggagaa aaaagcaaca gagataggtt aacgtaaaat gttcagcgaa aaaccgatat
     4021 gattcaccta tcctggtaat ttattatcag ggaatataaa gacttaatca ggggacaata
     4081 tgccacatca gcgcgtccgg tgtccgtctt gtaggtgccg gggaaattgc gcctcctcgc
     4141 tcactcggtc gctacgctcc ggccgtgaga ctgcggcggg cgctgcggac acatgcaaag
     4201 ttacccacag attccgtgaa taagcagggg actaacatgt gaggcaaaac ggcaaggcca
     4261 cgcaggtggc gtttttccat aggctccgcc ctcctgactg agttcacata aacagacgct
     4321 ttttcggtgc atctgtggga gccggtggct caaccatgaa tcagtcagga gtggcgaaac
     4381 ccgacaggac ttaaagatca tcaccgtttc cgatgaatcg ctccctcttg cgctctcctg
     4441 ttccaaccct gccgtttccc ggatacctgt tccgcctttc tcccttgcgg gaagtgtggc
     4501 gctttctcat agctcacact ctggtatctc ggctcggtgt aggtcgttcg ctccaagctg
     4561 ggctgtaagc aagaaccccc cgttcagccc gactgctgcg ccttatccgg taactgttca
     4621 cttgagtcca acccggaaaa gcacgcaaaa cgccactggc agcagccatt ggtaactggg
     4681 agttcgcaga ggatttgttt agctaaacac gcggttgctc ttgaagtgtg cgccaaagtc
     4741 cggctacact ggaaggacag atttggttgc tgtgctctgc gaaagccagt taccacggtt
     4801 aagcagttcc ccaactgact taaccttcga tcaaaccacc tccccaggtg gttttttcgt
     4861 ttacagggca aaagattacg cgcagaaaaa aaggatctca agaagatcct ttgatctttt
     4921 ctactgaacc gcgatccccg tcagttcaga ggaggacgat ggtgccaccg ttccaccctg
     4981 aacatcccgg atatagtttg cctgacatgc gaccagaaga aagcctgaaa aaatcaatat
     5041 aaaaagaaaa acaaccttta cctttttcat ataccttccc tgtatttaaa aaccccggta
     5101 ttcatccctg aacaccggaa gtctgtattt caaatcatcc ttgataactt ttgcttacca
     5161 gttaccatcc cggtaaacaa aggatacaaa gtaatcaaat ttactaatat cgattacatt
     5221 tttaaagtgt ggctgtaata tcgaaaccca tgatttttca acatcaaacc aaccattatt
     5281 aatattatcc tttaaaggca tccccagact ttcaatgaca gaaccatcat caccgaagtc
     5341 ttttgagtat tcaccacctt taaactcttc ggttttctta tcaaaccaat gaatatgtaa
     5401 tttaagcccc atatttacct cttaaagata ttttttaatg tttcgttttg gatccggccc
     5461 tttaacctgc ttacccgttt ttggatcgaa tgccccgagg tgttcgccat cactggcgcg
     5521 gtacccttca agctcaccgt gctgggaatc ccattcataa attttacgct ttttatcacc
     5581 ataccatcgg gcccgcttac caccaccacc ttgtttaggg gttttaggtt taccctcttt
     5641 caactctccc aaccccttaa tatcttcagt cttgggatca ggaaaataat catggccgta
     5701 atctttagtt cccttacgag gttttttctt ttcctcattt aatttatttt ctgcatcctt
     5761 cgcttttttc tccttttgtt tccggctctc catcgccccg gaaagcgcag ccttatccct
     5821 ggataaggat tcattcattt cgtttaaaga tgtctgggca gcttttaatt tctcattctg
     5881 attctgaata tccttatcaa gatagcgaac ctgatcctgc cacccggagc catattcatg
     5941 aggcgggtta taagtcacaa aatcatcttt atttgcctct gcctctttta cctttttatc
     6001 ggcttcctga acagcagccc ttgcaccggg gatcgccttc tctgtcgatg caatgcgact
     6061 gtttaaggtc gcaatatttt tatcttcagc atccagctca gctttcgctt tatcatactc
     6121 tcttttcagc ccctcttccg ggtgagcagc gtcccatgcc tgctggcgac gcttttcttc
     6181 ctccagacgc tgttttacct gtgccggagt aagaacatcc gtcaccgaca catagaccgg
     6241 tttctgtccg ctctctttcg ggaaacgaat aacggcttca cgggagttac caccggccgt
     6301 aaaaccagcc ggacgtgaat cacctttttc agcaataatg ccttttggcg gggctttcgc
     6361 ggccggaaca cctttaggta cgctcacctg cagagacggg agacccggaa tcgacacact
     6421 gaataccccc ggacgttttg tcggtttcgc atccaccaca ggaacactca ttggccggcc
     6481 ggtgacaacc gcaatatgct gccgctcgtc cttcacaata tccgccacac gtttagtgac
     6541 gctgaccgtc gcctggtcca gcggcaggga gctgaccggc gtctccgtta ccgtgtctgc
     6601 cggcaatgac gtcacgattt ttgacatcat tttcggatca tcttttgcta tctcagaagg
     6661 cagcactccg taaatcgcaa tcccccacag accaaactta aacggacctt tcagggcagc
     6721 cagcacatca gcaacagcgg ccgacaacgc atcgccggaa acggataaag ccagtccttc
     6781 agcccccgga gtggccaagg caggcagacc gaaggccatc gcggtggccg aagactgtcc
     6841 gccaccagag ctcccgctat gattgccgct gttaccgcca ttaccaccgg gtttactccc
     6901 gccgttacca aactcccccg ggttatagtt atgaatatcc ccgttaggtg tatgcgtcgt
     6961 accccagccc ggcccgctgt ttggatccgt accaccacct gatgaagggc cacctttacc
     7021 tgatgtaccg ttcacattcc cactggcctg accaccattg tgtcccagac ctgaattacc
     7081 cggacctcgt ccgtctccgc cactcatata cttttcctct ttgactttta aaacaataaa
     7141 ctaaaataaa atactgtaca tataaccact ggttttatat acagtataaa aattacgctg
     7201 ccttgttttt catgtcaagt ctgtaaattt gcgtttttgt gaaaatgatc aaaaaaacag
     7261 ccactcacac catgcgcaat cccctccaga tgcaacaaaa accagcacaa acggcgccgt
     7321 tctccggcct cagtatgttt tactgaaatc attatatgag ataccagaaa gccccctccg
     7381 ggacaggaaa agaaacgggg gtctggttcg ggttgttcgg tcactgaaca cggtcagaaa
     7441 ctgatgataa gatagcctgc ggatatataa ggggtctgac gctcagtgga acgaaaactc
     7501 acgttaaggg attttggtca tgagattatc aaaaaggatc ttcacctaga tccttttaaa
     7561 ttaaaaatga agttttaaat caatctaaag tatatatgag taaacttggt ctgacagtta
     7621 ccaatgctta atcagtgagg cacctatctc agcgatctgt ctatttcgtt catccatagt
     7681 tgcctgactc cccgtcgtgt agataactac gatacgggag ggcttaccat ctggccccag
     7741 tgctgcaatg ataccgcgag acccacgctc accggctcca gatttatcag ggcactgttg
     7801 caaagttagc gatgaggcag ccttttgtct tattcaaagg ccttacattt caaaaactct
     7861 gcttaccagg cgcatttcgc ccaggggatc accataataa aatgctgagg cctggccttt
     7921 gcgtagtgca cgcatcacct caataccttt gatggtggcg taagccgtct tcatggattt
     7981 aaatcccagc gtggcgccga ttatccgttt cagtttgcca tgatcgcatt caatcacgtt
     8041 gttccggtac ttaatctgtc ggtgttcaac gtcagacggg caccggcctt cgcgtttgag
     8101 cagagcaagc gcgcgaccat aggcgggcgc tttatccgtg ttgatgaatc gcgggatctg
     8161 ccacttcttc acgttgttga ggattttacc cagaaaccgg tatgcagctt tgctgttacg
     8221 acgggaggag agataaaaat cgacagtgcg gccccggctg tcgacggccc ggtacagata
     8281 cgcccagcgg ccattgacct tcacgtaggt ttcatccatg tgccacgggc aaagatcgga
     8341 agggttacgc cagtaccagc gcagccgttt ttccatttca ggcgcataac gctgaaccca
     8401 gcggtaaatc gtggagtgat cgacattcac tccgcgttca gccagcatct cctgcagctc
     8461 acggtaactg atgccgtatt tgcagtacca gcgtacggcc cacagaatga tgtcacgctg
     8521 aaaatgccgg cctttgaatg ggttcatgtg cagctccatc agcaaaaggg gatgataagt
     8581 ttatcaccac cgactatttg caacagtgcc gtttccaaaa ggtcgttgat caaagctcgc
     8641 cgcgttgttt catcaagcct tacggtcacc gtaaccagca aatcaatatc actgtgtggc
     8701 ttcaggccgc catccactgc ggagccgtac aaatgtacgg ccagcaacgt cggttcgaga
     8761 tggcgctcga tgacgccaac tacctctgat agttgagtcg atacttcggc gatcaccgct
     8821 tccctcatga tgtttaacgt ttgacatgag gggcggccaa gggcgccagc ccttggacgt
     8881 ccccctcgat ggaagggtta ggcaacactg cgtgttcgct cgaatgcctg gcgtgtttga
     8941 accatgtaca cggctggacc atctggggtg gttacggtac cttgcctctc aaaccccgct
     9001 ttctcgtagc atcggatcgc tcgcaagttg ctcggcgacg ggtccgtttg gatcttggtg
     9061 acctcgggat cattgaacag caactcaacc agagctcgaa ccagcttggt tcccaagcct
     9121 ttgcccagtt gtgatgcatt cgccagtgac tggtctattc cgcgtactcc tggatcggtt
     9181 tcttcttccc accatccgtc cccgcttcca agagcaacgt acgactgggc atacccaatc
     9241 ggctctccat tcagcattgc aatgtatgga gtgacggact cttgcgctaa aacgcttggc
     9301 aagtactgtt cctgtacgtc agcaagtgtc gggcgtgctt cttctccgcc ccaccactcg
     9361 acgatatgag atcgatttag ccactcatag agcatcgcaa ggtcatgctc agtcatgagg
     9421 cgcagtgtga cggaatcgtt gctgttggtc acgatgctgt actttgtgat gcctaacttt
     9481 gtttggaaat gttgaatact catactcttc ctttttcaat attattgaag catttatcag
     9541 ggttattgtc tcatgagcgg atacatattt gaatgtattt agaaaaataa acaaataggg
     9601 gttccgcgca cttttccccg aaaagtgcca cctgacgtct aagaaaccat tattatcatg
     9661 acattaacct ataaaaatag gcgtatcacg aggccctttc gtcttcaaga attttataaa
     9721 ccgtggagcg ggcaatactg agctgatgag caatttccgt tgcaccagtg cccttctgat
     9781 gaagcgtcag cacgacgttc ctgtccacgg tacgcctgcg gccaaatttg attcctttca
     9841 gctttgcttc ctgtcggccc tcattcgtgc gctctaggat cctccggcgt tcagcctgtg
     9901 ccacagccga caggatggtg accaccattt gccccatatc accgtcggta ctgatcccgt
     9961 cgtcaataaa ccgaaccgct acaccctgag catcaaactc ttttatcagt tggatcatgt
    10021 cggcggtgtc gcggccaaga cggtcgagct tcttcaccag aatgacatca ccttcctcca
    10081 ccttcatcct cagcaaatcc agcccttccc gatctgttga actgccggat gccttgtcgg
    10141 taaagatgcg gttagctttt acccctgcat ctttgagcgc tctgatctga atatcgaggg
    10201 actgctggct ggttgagacc cgcgcataac caaaaattcg cataaaaatg taccttaaat
    10261 cgaatatcag acacgatgtg tctattatgc caaaatgacg atttaatgga cactcaaacg
    10321 aagccgtttt actatgtctg ataatttata atatttcgaa cggttgcagt tgtgttaaaa
    10381 aagccgtcag gcagggaggc cgatatgccc gttgattttt tgaccactga gcaggttgag
    10441 agttatggca ggttcactgg cgaacccgat gaacttcagc tggcgcgtta ttttcatctt
    10501 gatgaagcgg ataaagaatt tatcgggaaa agccggggtg atcacaatcg acttggtatt
    10561 gccctgcaaa tcgggtgtgt gcgttttctg ggcacttttc ttactgacat gaatcatatt
    10621 ccttccggcg tccggcattt taccgccaga cagctcggga ttcgtgatat caccgttctt
    10681 gcagaatacg gtcagaggga aaatacccgc cgtgagcatg cagcgctgat acgtcagcac
    10741 tatcagtatc gtgaatttgc ctggccctgg acatttcgcc ttacccgtct tttatatacc
    10801 cggagctgga taagcaacga acgtcctggc ctgcttttcg acctggcgac agggtggctt
    10861 atgcaacatc gtattattct ccccggagcc accacgctga cccggttgat ttcagaggta
    10921 agggaaaagg cgacgttgcg cctgtggaac aaactggcac tgataccgtc agccgaacag
    10981 cgttcacagc tggagatgct gctggggcca actgattgca gccgcctgtc tttactggaa
    11041 tcactgaaaa aaggccctgt gaccatcagt ggtccggcgt ttaatgaagc aattgaacgc
    11101 tggaaaactc tgaacgattt tggcctgcat gctgaaaacc tgagtacact cccggctgtg
    11161 cgcctgaaaa atctcgcacg ttatgctggt atgacttcgg tgttcaatat tgccaggatg
    11221 tcaccgcaga aaaggatggc ggttctggtt gcctttgtcc ttgcatggga aacgctggcg
    11281 ctggatgatg cactggacgt tctggacgcc atgctggccg ttatcatccg tgacgccaga
    11341 aagattgggc agaaaaaacg gctccgctcg ctgaaggatc tggataaatc tgcattggcg
    11401 ctcgccagcg catgttcgta cttgctgaaa gaagaaacac cggacgaatc gattcgtgct
    11461 gaggtgttca gctacatccc taggcaaaag ctggctgaaa tcatcacgct tgtccgtgaa
    11521 attgcccggc cctcagacga taattttcat gacgaaatgg tggagcagta cgggcgcgtt
    11581 cgtcgtttcc tgccccatct gctgaatacc gttaaatttt catccgcacc tgccggggtt
    11641 accactctga atgcctgtga ctacctcagc cgggagttca gctcacggcg gcagtttttt
    11701 gacgacgcac caacggaaat catcagtcag tcatggaaac ggctggtgat taacaaggaa
    11761 aaacatatca cccgaagggg atacacgctc tgctttctca gtaaactgca ggatagtctg
    11821 agacggaggg atgtctacgt taccggcagt aaccggtggg gagatcctcg tgcaagatta
    11881 ctacagggtg ctgactggca ggcaaaccgg attaaggttt atcgttcttt ggggcacccg
    11941 acagacccgc aggaagcaat aaaatctctg ggccatcagc ttgatagtcg ttacagacag
    12001 gttgctgcac gtcttggcga aaatgaggct gtcgaactcg atgtttctgg cccgaagccc
    12061 cggttgacaa tttctcccct cgccagtctt gatgagccgg acagtctgaa acgactgagc
    12121 aaaatgatca gtgatctgct ccctccggtg gatttaacgg agttgctgct cgaaattaac
    12181 gcccataccg gatttgctga tgagtttttc catgccagtg aagccagtgc cagagttgat
    12241 gatctgcccg tcagcatcag cgccgtgctg atggctgaag cctgcaatat cggtctggaa
    12301 ccactgatca gatcaaatgt tcctgcactg acccgacacc ggctgaactg gacaaaagcg
    12361 aactatctgc gggctgaaac tatcaccagc gctaatgcca gactggttga ttttcaggca
    12421 acgctgccac tggcacagat atggggtgga ggagaagtgg catctgcaga tggaatgcgc
    12481 tttgttacgc cagtcagaac aatcaatgcc ggaccgaacc gcaaatactt tggtaataac
    12541 agagggatca cctggtacaa ctttgtgtcc gatcagtatt ccggctttca tggcatcgtt
    12601 ataccgggga cgctgaggga ctctatcttt gtgctggaag gccttctgga acaggagacc
    12661 gggctgaatc caaccgaaat tatgaccgat acggcaggtg ccagcgatct tgtctttggc
    12721 cttttctggc tgctgggata ccagttttct ccacgcctgg ctgatgccgg tgcttcggtt
    12781 ttctggcgaa tggaccatga tgccgactat ggcgtgctga atgatattgc cagagggcaa
    12841 tcagatcccc gaaaaatagt ccttcagtgg gacgaaatga tccggaccgc aggctccctg
    12901 aagctgggca aagtacaggc ctcagtgctg gtccgttcat tgctgaaaag tgaacgtccc
    12961 tccggactga ctcaggcaat cattgaagtg gggcgcatca acaaaacgct gtatctgctt
    13021 aattatattg atgatgaaga ttaccgccgg cgcattctga cccagcttaa tcggggagaa
    13081 agccgtcatg cagttgccag agccatctgt cacggtcaaa aaggtgagat aagaaaacga
    13141 tataccgacg gtcaggaaga tcagttggga gctctggggc tggtcactaa cgccgtcgtg
    13201 ttatggaaca ctatttatat gcaggcagct ctggatcatc tccgggcgca gggtgaaaca
    13261 ctgaatgatg aagatatcgc acgcctctcc ccgctttgcc acggacatat caatatgctc
    13321 ggccattatt ccttcacgct ggcagaactg gtgaccaaag gtcatctgag accattaaaa
    13381 gaggcgtcag aggcagaaaa cgttgcttaa cgtgagtttt cgttccactg agcgtcagac
    13441 ccctataact caatgagaaa aaagaattaa aggtaaggag acgctcatga gacgttccgg
    13501 cagcaaactg tgtcttatcg ccatgataac agcgacagca actctcactg cctgtgctcc
    13561 aaagggcagc gtggaacagc atacccggca ttacgtatat gcttcagatg acggttttga
    13621 tcccaatttt tccacccaga aagctgacac aacacgaatg atggtgcctt ttttccggca
    13681 gttctgggat atgggcgcaa aggataaagc gaccggaaaa tcacggagtg atgtgcagca
    13741 acgcattcag cagtttcaca gtcaggaatt tttaaactca ctccaaggca caacacaatt
    13801 tgcgggtacc gattaccgca gcaaagacct cacaccgaaa aaatcaaggc tactggctga
    13861 caccatttca gctgtttatc tcgatggcta tgaaggcaga cagtaagtgg atttaccata
    13921 acgcgtcatt acgcgcaccg ctcagacggg ctcagggcgt ttccggcggc tacgggataa
    13981 aacaggcaac aacccccccg gaaaactgcc ggaaacgcgc ccgataaatt ttatcctaat
    14041 gcatgcctat gcacgcaact gcatggcata tgttttgacg taaaatggat gccgtaagcc
    14101 cttttttacc gactttctgc ttcatcagcc tgactgacac gaccatattc tttcagaccg
    14161 ccccctgcta aacttccttc atattgccgc attaacccgg gaggctccgc aatgagcaac
    14221 actacacact acgaaaacgc caactttctt cgggaactgg ctgaaagcct gccccgcata
    14281 ctgccggaag gtggcccgga caaagctgcg ctgttgcagc gactggctaa cgaagaactg
    14341 gcccaggcag agtatgaaga tcaggttcgc gccaaagtga ccgccgcccg tgctgacacg
    14401 cgtccgggta tgaccacgga acaactccgc cagcgcctgc atggccgtta tcaggaactg
    14461 cgcgatgccg tatgacgtgg aatggaagca gggagccatc gaggatgtaa cgacgctgtt
    14521 tgactatatc gcggaaaatt catccctgtg ggatgcgcag aacgttaccg accgggttct
    14581 cgctgcggcg gacaaactgg ccgacttccc gcgactctat gaagtggact cacgctatgg
    14641 cgaggacgtt cgccggatca gtctgatggg acagcatgtc ctctatgatg ttgatgacca
    14701 gaccagaaaa gtccgggttc tggccgtggt cggccagcgc cagaatcccc atattgttct
    14761 ctaataaccg gtgacgggga cgcaattcat tgcgtggccg tcgccggttg gacaagcaca
    14821 gcgcgtcagc gttttcccca cggccaccac cggcgcggtg ttccggccgg ggtctctgct
    14881 gtctccggtt tgtgttccag cagtctcatg gactgcattt cctgccgtag cccggccacc
    14941 tcctccctga gtgcttttat ctccgcgatc aacgcgtcgg aggccatttt ttcagtctca
    15001 cccgacagtc tcaactcgtc ccgctcgtga gtctcatcct gtcttaactc accgtacacc
    15061 cggataagct cgctggtatc caccacccgg ccgccatcag cttccgtacg gtatgatacg
    15121 cggcctttcg ccatatcccg atacagggaa cttcgggctt tacccgtcag ttccgtcgcc
    15181 tgtctcaccg tcacccacgc cattgtctca ccccgctatt tttgagacag tatacctgac
    15241 aggcgcacac catgcccgga aggaaagaat c
//
