LOCUS       CP056948.1             17237 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CP056948.1 Escherichia coli strain RHB42-C02 plasmid pRHB42-C02_2,
            complete sequence.
ACCESSION   CP056948
VERSION     CP056948.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 16:36:44
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17237
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..858
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRF
                     DFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECGLA
                     TESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDVSEE
                     AVAAARRSRVEWENRQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIKRARA
                     RRDANRERQDIVTLVKRQLTREIAEGRFTASREAVKREVERRVKERMILSRNRNYSRLA
                     TASP"
     protocluster    1..17237
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5247:7237]"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5248..7237
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
     cand_cluster    1..17237
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /kind="single"
                     /product="LAP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17237
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="LAP"
                     /region_number="1"
                     /rules="((((goadsporin_like or PF00881 or TIGR03605) and
                     (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or
                     TIGR03602) and not cyanobactin_synth)"
                     /tool="antismash"
     CDS             1793..2677
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MDLYHFTAIPMLHSILASEGLREGYLTLYDGTILYNKVWLTTSPL
                     PYGHGLCNGTEKLSESEKSFMRRVGNISESTSINGTHNKKLIRLKIDTEWIKKQPGFCS
                     YKKLMRDLGQPKAYVKYVGAMGVEGARGMTDEQISKIMRKGNTKEDTWYIFNGVIPPSK
                     IVSVEYMETKDKYIPYDFELHGRGYIENSGIYPISNLLLSDLNHTMRNITFLPGSVIAF
                     CHKANSEENILFRHVLFTCSISLRNFSVLIATGDETSFYIHLDVLKSWTQKNSKVLCQL
                     FEKARESYHRYYG"
     CDS             complement(3218..3781)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MDIIEKRITKRHLSESELSGVNYYNCIFERIQLDNFNFRDCEFEK
                     CRFVNCSIKNLKLNFFKLIDCEFKDCLLQGVNAADIMFPCTFSLVNCDLRFVDFISLRL
                     QKSIFLSCRFRDCLFEETDLRKSDFTGSEFNNTEFRHSDLSHCDFSMTEGLDINPEINR
                     ILSIKIPQEAGLKILKRMGVVVGG"
     CDS             complement(3785..4516)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 95.1; E-value:
                     9.3e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MTIPLLEINSLSFSYKVNLPPVFNNLSLKIEQGELIGLLGENGAG
                     KTTLFNLIRGGVSNYEGTLKRNFSGGELVSLPQVINLSGTLRNEEVLDLICCFNKLTKK
                     QAWTELNHKWNDNFFIRYDKIRRKRTYTVSYGEKRWLIISLMLTLCKNARLFLLDEPTV
                     GIDIQYRMMLWELINKITADGKTVFFSTHIFDELTRDKIPFYMLSKNSINRYSDMSDFI
                     QSNNETTPEKAFIKEVMGTGD"
     CDS             complement(4513..5238)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MVTLKMAIIFLMEQIRTPFSLIWTIMSPTVLFFFLHFNEIELHYG
                     DTAWLGKQISWFVGYISFSVVLFNYCLYLVGRRESGFIATFVHNMDGRLLFIRSQLIAS
                     LIMSILYVFFFILVVLTGFQASPDYQIVMIILKSIYINAFMMVSLTFMASFRVTFQTAS
                     TIYSVLITVCMVSGIVSLKYNEGIVYWINQVNPIAIYSTILQSDQELSLMTIFFYSIML
                     IISIISALTFKTEPVWSSQ"
     CDS             complement(5248..6438)
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6"
                     /sec_met_domain="YcaO (E-value: 1e-16, bitscore: 53.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVYSNLMSAWPATMAMSPKLNRNMPTFSQIWDYERITPASAAG
                     ETLKSIQGAIGEYFERRHFFNEIVTGGQKTLYEMMPPSAAKAFTEAFFQISSLTRDEII
                     THKFKTVRAFNLFSLEQQEIPAVIIALDNITAADDLKFYPDRDTCGCSFHGSLNDAIEG
                     SLCEFMERQSLLLYWLQGKANTEISSEIVTGINHIDEILLALRSEGDIRIFDITLPGAP
                     GHAVLTLYGTKNKISRIKYSTGLSYANSLKKALCKSVVELWQSYICLHNFLIGGYTDDD
                     IIDSYQRHFMSCNKYESFTDLCENTVLLSDDVKLTLEENITSDTNLLNYLQQISDNIFV
                     YYARERVSNSLVWYTKIVSPDFFLHMNNSGAININNKIYHTGDGIKVRESKMVPFP"
     CDS             complement(6419..7237)
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7"
                     /sec_met_domain="PF00881 (E-value: 8.1e-10, bitscore: 31.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKHELSLVEVTHYTDPEVLAIVKDFHVRGNFASLPEFAERTFVS
                     AVPLAHLEKFENKEVLFRPGFSSVINISSSHNFSRERLPSGINFCDKNKLSIRTIEKLL
                     VNAFSSPDPGSVRRPYPSGGALYPIEVFLCRLSENTENWQAGTNVYHYLPLSQALEPVA
                     TCNTQSLYRSLSGGDSERLGKPHFALVYCIIFEKALFKYRYRGYRMALMETGSMYQNAV
                     LVADQIGLKNRVWAGYTDSYVAKTMNLDQRTVAPLIVQFFGDVNDDKCLQ"
     CDS             complement(7239..8093)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04424"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_8"
                     /sec_met_domain="TIGR04424 (E-value: 2e-88, bitscore:
                     288.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINILPFEIISRNTKTLLITYISSVDITHEGMKKVLESLRSKQGI
                     ISEYLLDKLLDESLIDKDKGKEFLITTGVINKTKTSPLWVNSVIISDVPHLFSNAREQW
                     KSDGVFVSHIIDIKDNNINVSDSTLIWLHLENYHSDIVKRIYSKFESNPGVAFIQSYYL
                     KESFRIDGVYSPDLGTPCHFCHIERWLSREEKSFRRNEMSWANLLQLLKKYQMTLPALA
                     LGESERGFSYHLIKRRLQELTGTSLVKSHVDNFMSSVSADLITCILCKEPVIHWQACSC
                     LER"
     CDS             complement(8153..8359)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MELKASEFGVVLSVDALKLSRQSPLGVGIGGGGGGGGGSCGGQGG
                     GCGGCSNGCSGGNGGSGGSGSHI"
     CDS             8815..9111
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MIQTRNQYLQFMLVMLAAWGISWGARFVMELAVLLYGPGKNYLFF
                     SHGAVLMYLLCVFLVYRRWIAPLPVVGQLRNVGVLWLVGAMAVVYIGVFLLDR"
     CDS             9126..9608
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MSSVFKGRVSMKFMECAVRDVIYGTNVRIVKPVNIYECELRDNVF
                     VGPFVEIQKGCVIGSGSRIQSHTFICENVTLGENCFIGHNVTFANDLFRSGAPDPSPDN
                     WISITLGDSVTVGSGAIILSPYICSGAVIGAGSVVVKPIENKGIYAGNPARLLRIL"
     CDS             complement(10012..10365)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MMDKRRTIAFKLNPDVNQTDKIVCDTLDSIPQGERSRLNRAALTA
                     GLALYRQDPRAPFLLCELLTKETTFSDIVNILRSLFPKEMADLNSSTIIQSSSQSEQKS
                     DEETKKNAMKLIN"
     CDS             complement(10365..11327)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MLVFIDDGSTNIKLQWQENDGTIKQHISPNSFKREWAVSFGDKKV
                     FNYTLNGEQYSFDPISPDAVVTTNIAWQYSDVNVVAVHHALLTSGLPVSEVDIVCTLPL
                     TEYYDRNNQPNTENIERKKANFRKKITLNGGDAFTIKDVKVMPESIPAGYEVLQELDEL
                     DSLLIIDLGGTTLDISQVMGKLSGISKIYGDSSLGVSLVTSAVKDALSLARTKGSSYLA
                     DDIIIHRKDNNYLKQRINDENKISIVTEAMNEALRKLEQRVLNTLNEFSGYTHVMVIGG
                     GAELICDAVKKHTQIRDERFFKTNNSQYDLVNGMYLIGN"
     CDS             11843..12526
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MSRFILGDCVRVMATIPDNAIDFILTDPPYLVGFRDRSGRTIAGD
                     VNDDWLQPASNEMYRVLKKDALMVSFYGWNRIDRFMAAWKRAGFSVVGHLVFTKSYTSK
                     SAYVAYRHECAYILAKGRPALPPKPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESFTHP
                     NAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLATVQRAMQQGAANDNWF
                     EPEAA"
     CDS             12527..12736
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MNYAGHENLAEVANAMCDLRARLNDMEHRCRFDSDVLVERLARQT
                     LYRANRLFMEAYTEILELDACFKD"
     CDS             12749..13183
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MYGTCETLCRELEAKYPGDTPLMLVIWSPEEIQALADGMEISLTD
                     HEIRAVLARMEDIPEDQRTESGISSAAVMEIISNVSENRQVTVPAELLASLIQTAEQAL
                     WKREWAARDNGLVVPECVTRRQAVVNQARALLKNNTREND"
     CDS             13228..13998
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MNETLNALICRHARNLLLAQGWPEETDVDQRNPNHPGWISIYVRL
                     DAPRLATLLINRHGGVLPPHLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVSFPY
                     AGEWLAEDEIRAVLAAVRDAIRSICYQVADDARRIRAALTTTGQTLLTRQTRRFRLVVK
                     ESDHPCWLDEDDENLPVVLDAIVNRGARFSSVEMYLVSDCIEHILSSGLACDVLRIPDE
                     PPRRWFDRGVLREVVREARVEIRSMADALAKIRD"
     CDS             14357..14782
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MQYAKPVTLNVEECDRLSFLPYLFGNDFLYAEAYVYALAQKMMPE
                     YQGGFWHFIRLPDGGGYMMPDGDRFHMVNGANWFDRTVSADAAGVILTSLVINRQLWLY
                     HDSGDAGLTQLYRMRDAQLWRHIEFHPECNAIYAALD"
     CDS             14829..15251
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MYCTVKEIIREVLDTDVPDSECVFAVVLTRGDVRHMAQDWSLSDD
                     ELETVMQRLDDAFEYGADVSVVHGVVRELMEEKRASRQVTVPAVMLEKVMALAGSEMKR
                     LYAVGSENGGDGDAFVREEREAMDVVLQALDGETMS"
     CDS             15248..15439
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MNISTESREILRNYRAVINARRREMGQKPLTTAQIVDEICDFVAN
                     QQAVFLGGHYILQGSRNR"
     CDS             16473..16703
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIARS
                     FHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
ORIGIN
        1 gtgactgatc ttcaacaaac gtattaccgc caggtaaaga acccgaatcc ggtgtttaca
       61 ccccgtaaag gtgccggaac gctgaagttt tgcgaaaaac tgatggaaaa ggcggtgggc
      121 ttcacctccc gttttgattt cgccattcat gtggcgcatg cccgttcgcg tggtctgcgt
      181 cgacgcatgc caccggtgct gcgtcgacgg gctattgatg cgctgctgca ggggctgtgt
      241 ttccactatg acccgctggc caaccgcgtc cagtgttcca tcaccacgct ggccattgag
      301 tgcggactgg cgacagagtc cggtgcagga aaactctcca tcacccgtgc cacccgggct
      361 ctgacgttcc tgtcagagct gggactgatt acctaccaga cggaatatga cccgcttatc
      421 gggtgctaca ttccgaccga tatcacgttc acatctgcac tgtttgctgc cctcgatgta
      481 tcagaggagg cagtggccgc cgcgcgccgc agccgtgtgg aatgggaaaa cagacagcgc
      541 aaaaagcagg ggctggatac cctgggtatg gatgagctga tagcgaaagc ctggcgtttt
      601 gtgcgtgagc gtttccgcag ttaccagaca gagcttaagt cccggggaat aaagcgtgcc
      661 cgtgcgcgtc gtgatgcgaa cagggaacgt caggatatcg tcaccctggt gaaacggcag
      721 ctgacgcgcg aaatcgcgga agggcgcttc actgccagtc gtgaggcggt aaaacgtgaa
      781 gtggagcgtc gtgtgaagga gcgcatgatt ctgtcacgta accgtaatta cagccggctg
      841 gccacagctt ccccctgaaa gtgacctcct cagaataatc cggcaagcgc cggaggcatt
      901 tgcacgcctg aagcccgcta gcgcacaaaa aatcagcgct acatacaaaa aacaacctca
      961 tcatccacct tctggtgcat ccggtccccc ctgtttttga tgaaaaactc gtctcacaga
     1021 cgggcaattt tgcttatcca cattaaactg caaggggctt ccctataagg ttacaaccgt
     1081 tcatgtcata aagcgccagc cgccagcgtt acagggtgca atgtatcttt taaacacctg
     1141 tttatatctc ctttaaacta cctaattaca ttcatttaaa aagaaaacct attcagtgtc
     1201 tgtcctgtgg acagacagat atgcacctcc caccgcaagc ggcgggcccc gaccggagcc
     1261 actttagtta caacacacga aaacagcctc cagaaaaacc ccggtccagc gcagaactga
     1321 aaccacaaag cccctccctc ataactgaaa agcggccccg ccccggccct tcgggccgga
     1381 acagagtcgc ttttaattat gaatgttgta actaaacatc atcatcgctg tcagtcttct
     1441 ggctggaagt cctcagtaca cgctcgtaag cggccctcac ggcccgctaa cgcggagata
     1501 cgccccgact tcgggtaaac cctcgtcggg accactccga ccgcgcacag aagctctctc
     1561 atggctgaaa gcgggtatgg tctggcaggg ctggggatgg gtaaggtgaa atctatcaat
     1621 cagtaccggc ttacgccggg cttcggcggt tttactccgg tatcacatgt aaccacagcg
     1681 tgccgcctta catgccgctg aagcggcatt cagtagacag gctatgcacg actcgccagt
     1741 ctggcctgaa catgatataa aatgaatata aatagacaga atagggttat ttatggattt
     1801 atatcacttt acagcaattc ctatgttgca ttccatactt gcatctgaag gcctgagaga
     1861 aggatatcta acgttgtatg atggaacaat tttgtataat aaagtatggt taacgacatc
     1921 tccattacca tatggtcacg gattatgtaa cggtactgaa aaattaagtg aatcagaaaa
     1981 atcatttatg cgaagagtcg gtaatatatc tgagtctacg tctataaatg gaacacataa
     2041 taaaaagtta ataaggttaa aaatagatac tgaatggata aaaaagcagc ctggattttg
     2101 ctcatataaa aagctgatgc gtgaccttgg acaacctaaa gcttatgtta agtacgtagg
     2161 tgcaatgggg gttgaggggg caagggggat gaccgatgag cagataagta aaattatgcg
     2221 aaaaggtaac acaaaagaag atacctggta tatctttaat ggggtcatcc caccttcaaa
     2281 aatagtctct gttgaatata tggaaactaa agataaatat ataccatatg attttgaatt
     2341 gcatggaagg ggatatatag aaaactccgg catttatccg atttcgaatt tattattatc
     2401 tgatctgaat catacaatgc gaaatattac atttttacca ggttctgtca tagcgttttg
     2461 tcataaagca aattcagaag aaaatatttt attcagacat gtattattca catgttcaat
     2521 ctccttgaga aatttttcag tactgatagc aacaggtgat gagacatctt tctatattca
     2581 tctggatgta ttaaaaagtt ggactcaaaa aaacagtaaa gtactatgcc aactttttga
     2641 aaaagcacgt gaaagttacc acagatacta tggttagaaa ccactgcggg gagaacatca
     2701 gtggcacaaa actagaccgc ccggaaccgg gacgcttact gatggacagt catcgcaatg
     2761 atatcttgct ggttgagcag ataggggctc cgtgggaatt tctgcgataa cacccgctaa
     2821 gcgatttctc cctgacggaa atcacttgtt tttcgttcag aggcaggcaa gaggaatatt
     2881 catccccaaa aacggcgttt tcatatgcgg aaaacgctgc cggatagtcg aatagtacga
     2941 caaactgact tctgacgttt tccgtacatt tcagattcag taaccccgaa tatttggggt
     3001 tggtatggct aacgccttga atttcaatga acaatatttt gttaccgtgt actgtcgcag
     3061 aaatgcccac ggaaccccga gatggagaac tcagtcaatg ttccattctt tctgaaatat
     3121 gtgtggggac actgatctgt cgggagccgg atgcggtagt tccgcaggtc cggttctgag
     3181 gaggggcccg tccgggcaac cggcgggtct actcacctca tccccctaca accactccca
     3241 ttcgtttaag tatttttaaa cctgcttcct gtggtatctt tatagataag atcctgttta
     3301 tctcaggatt tatatcgaga ccttctgtca ttgaaaaatc acagtgagac aaatcagaat
     3361 gtctgaactc tgtattatta aactccgaac cagtaaaatc agatttacga aggtctgttt
     3421 cctcaaataa acaatcacgg aagcgacagg ataaaaaaat agatttctgt aaccgtaaac
     3481 taataaaatc aacaaatctc aaatcacaat ttacaagaga aaaagtacag ggaaacataa
     3541 tgtctgctgc atttactcct tgtaataaac aatctttgaa ttcacagtca ataagtttaa
     3601 aaaaattaag ttttaaattc tttattgagc agtttacgaa gcgacatttt tcgaactcac
     3661 aatcgcgaaa gttaaagttg tcaagctgta ttcgttcaaa tatacaattg taataattta
     3721 cacctgataa ttcactttca ctgaggtgtc gttttgtgat tcttttttct attatatcca
     3781 tgtgtcagtc tcctgttccc ataacttctt taataaatgc cttttctgga gttgtttcat
     3841 tattggattg aataaaatca ctcatatcag aataacgatt tatactattt tttgaaagca
     3901 tatagaaggg gattttatct cttgttaatt catcaaaaat atgagttgag aaaaataccg
     3961 ttttcccgtc agcggtgatc ttatttatca gttcccataa catcattctg tactgaatat
     4021 caatgcctac agttggttca tccagtaaaa ataaacgggc atttttgcaa agcgttagca
     4081 tcaaagatat gataagccaa cgcttctctc cataacttac cgtgtaagtc cttttacgtc
     4141 ttattttatc atagcgaatg aaaaaattat cattccattt atgattaagc tctgtccatg
     4201 cctgtttttt agttaactta ttgaagcagc aaatcaaatc aagaacctcc tcattcctta
     4261 gtgtacctga aagatttatg acttgaggta gacttactaa ttctccacca gagaaatttc
     4321 gcttgagggt cccttcataa ttactgactc cgcccctgat aaggttaaaa agagtggtct
     4381 tcccggctcc attttctcca agcagaccta tcaactctcc ctgctcaatc ttaagcgaca
     4441 gattattgaa aacagggggt aaatttactt tatatgaaaa gctcagagag ttgatttcta
     4501 aaagaggtat ggtcattgag aactccagac tggctcagtt ttgaaggtta gtgctgaaat
     4561 aatacttatg attaacatta tactatagaa aaatatcgtc atcagagaca actcctggtc
     4621 tgactggagt attgtagaat agatggcgat aggattaacc tgatttatcc agtaaacgat
     4681 cccctcatta tattttaatg atacaattcc tgataccata cagacagtta ttaatacaga
     4741 atagatagtg ctggctgttt ggaatgtgac tctgaacgat gccatgaaag tgagtgaaac
     4801 catcataaat gcatttatgt atatcgattt taaaataatc attactattt gataatctgg
     4861 acttgcctgg aatcctgtta gtacgactaa aatgaaaaaa aacacataca aaatagacat
     4921 gataagtgag gctattaatt gagaacgaat aaataatagt cgaccatcca tattatgcac
     4981 gaaggtagca ataaaaccac tttctcttct tccgaccaga tacagacagt aattaaacag
     5041 aacaacagaa aaagaaatgt agcctacaaa ccatgatatt tgttttccga gccatgctgt
     5101 atcaccataa tgaagttcaa tttcattgaa atgaaggaaa aagaacaaca ctgtaggtga
     5161 cataattgtc catattaagc tgaaaggggt tctgatttgt tccatcagaa aaattatcgc
     5221 catttttaat gtaaccattt gttatcctta tgggaatggt accatctttg attctctgac
     5281 tttaataccg tccccggtat ggtaaatttt attattaatg tttattgcac ctgagttatt
     5341 catatgaagg aaaaaatcag ggcttactat ttttgtgtac cagacaaggc tgttacttac
     5401 tctttccctg gcatagtaaa caaaaatatt atcagaaatt tgttgaagat agtttaataa
     5461 atttgtgtct gacgtaatat tttcctcaag cgttaacttg acatcatcag acagtagtac
     5521 cgtattttca cacaaatccg taaacgactc gtacttgttg catgacataa agtgacgctg
     5581 gtaactatca ataatgtcat catcagtata accgccaata agaaagttgt gcaggcatat
     5641 atacgattgc cacaattcca ctacggattt acaaagtgct tttttcagac tattagcata
     5701 ggataatccg gtactgtatt ttattcgact gattttgttt tttgtgccat acagggttag
     5761 tactgcgtgt ccaggagctc cgggcagggt gatatcgaaa atcctgatat ctccttctga
     5821 cctgagagcc agtaaaatct catctatatg atttatgcct gttactattt cactggatat
     5881 ttcagtattg gcttttccct gtaaccagta aagaaggagg gactgtctct ccataaattc
     5941 acacaaggaa ccttctatgg catcgttcaa actaccatga aagctacatc cgcatgtatc
     6001 tctgtcagga taaaatttca gatcatctgc agcggttata ttgtcgagtg caattatgac
     6061 tgcaggtatt tcttgttgtt caaggctaaa cagattaaag gctctgaccg ttttaaattt
     6121 atgggttatg atttcatcgc gggtcagtga tgagatctga aaaaatgctt cggtaaaagc
     6181 ctttgcagca gatggaggca tcatctcata taatgttttc tgaccaccgg tgactatctc
     6241 attaaaaaaa tgacggcgtt caaaatattc acctattgcc ccctgaattg acttcagagt
     6301 ttcaccggcc gcgctggctg gtgtaatacg ctcatagtcc catatctgag aaaacgttgg
     6361 catatttctg ttcagttttg gactcatagc cattgtggcc ggccatgcgg acataaggtt
     6421 actgtagaca tttatcatcg tttacatctc caaaaaactg aacgatcagt ggcgctacag
     6481 tcctctgatc cagattcatt gtttttgcta cgtatgaatc ggtatatccc gcccataccc
     6541 ggtttttcag tcctatttga tctgcaacca atactgcgtt ctgatacatc gaacctgttt
     6601 ccattaaggc catccggtat cctctgtagc gatatttgaa caaagctttt tcaaaaataa
     6661 tgcaatagac gagagcaaaa tggggtttac caagacgttc cgaatcccca ccggacaggc
     6721 ttcggtagag tgactgagta ttacatgtag caacaggttc cagtgcctga cttagcggca
     6781 ggtagtgata aacattagtt cctgcctgcc agttttctgt attttcagat aatctgcata
     6841 aaaaaacttc aatcgggtac aatgcccccc cagaaggata aggtcttctt acagagccag
     6901 gatcaggtga gctgaatgca ttgactaata acttttcaat agtacgaatg gaaagtttat
     6961 ttttgtcgca aaagtttatt cctgatggga gcctttcacg actaaaatta tgtgatgagg
     7021 atatgtttat tacggagctg aaacctggcc tgaagagaac ttctttattt tcaaatttct
     7081 ccagatgggc aagaggtacc gcggacacga aagttcgttc agcaaattcg gggagggaag
     7141 caaagttacc tctgacatga aaatctttaa caatggccag aacttcagga tctgtgtaat
     7201 gcgttacttc cactaaagag agttcgtgtt ttgacatgtt atctctccag acagctgcaa
     7261 gcctgccagt gaattaccgg ctctttacat aaaatacagg tgattaaatc agcgctaaca
     7321 gatgacataa agttatcgac atgactttta accagtgaag tacctgtcaa ctcctgaagt
     7381 cgccgtttta ttaaatgata gctgaatcct ctttctgatt cgcctaaagc caatgctggt
     7441 agtgtcattt ggtatttttt cagtaactga agtaagtttg cccaggacat ttcgttacgt
     7501 ctgaagcttt tttcttccct gctcagccat ctctctatat gacaaaaatg gcagggagta
     7561 ccaagatcag gtgaatatac tccatctatc ctgaatgact cctttaggta gtagctttgg
     7621 atgaaggcaa caccagggtt actttcaaat tttgaataga ttctttttac aatgtctgaa
     7681 tgatagtttt cgagatgtaa ccagattagt gttgaatcgc tcacattaat attattatct
     7741 tttatatcaa tgatatgaga aacaaaaaca ccatcagatt tccattgttc ccgggcatta
     7801 ctgaaaagat gtggaacatc gcttattatg actgagttta cccagagagg tgatgttttc
     7861 gttttattta tcacgcctgt ggtaataaga aactctttgc ccttgtcttt atcaataagc
     7921 gattcgtcca gtagtttatc aaggaggtat tcagaaataa taccctgttt ggatcgtagg
     7981 ctttcgagta cttttttcat tccctcatgt gtaatgtcta ctgaagaaat gtaggtaata
     8041 agcagggtct ttgtatttct ggaaattatc tcaaatggca gaatattgat catatctttt
     8101 ccttttttaa tatcagggag caccatgctc cctgaacggt taattcaacg tatcagatat
     8161 gtgaaccact tccgccgctg ccaccgtttc caccactaca accgttgctg caaccaccac
     8221 aaccgccacc ttgaccaccg cagctaccgc cgccgccgcc gccaccacca ccaatgccaa
     8281 cacctaatgg agactggcgt gataatttaa gagcatcaac ggacaaaact acaccaaatt
     8341 cactcgcttt taattccata aggactcctt ttttaaggga aattaatgct tatgacatct
     8401 gaatagtatg ttggccaaca ctagttactt gccgtaatta actatatttt gcaatgataa
     8461 tttgaactaa atttgtacgc ctgttaaata tttaataata atatcagtcg gttatgtttg
     8521 tgcggttatt gtttttttta caaaaattaa tattgtgttt acattttgct ttcagttgct
     8581 gtcaggatgt cacgctaccc ctttaagccc ccactggtct ggcagggccg ggggtgggta
     8641 aggtgaaacc tgtcaatcag taccggctta cgccggtatc atatgcaaca actgagtgcc
     8701 gccttccatg ccgctggtgc ggcatatcct ggtgacgata tctgaattgt tatagatatg
     8761 tatatacgta gtaatgacaa gaataggata agttaaaaat ttacaggaga tgcaatgatt
     8821 cagacacgta atcaatatct gcagtttatg ctggttatgc tggctgcatg gggcattagc
     8881 tggggagcca gatttgtcat ggagctggcc gttctgcttt atgggccagg aaaaaactat
     8941 ttgttcttca gtcatggtgc tgttctgatg tacctgctgt gtgttttctt ggtataccgc
     9001 cgttggatag ctccgctacc ggtcgttggt cagctgcgca acgttggcgt actgtggctg
     9061 gtcggtgcga tggccgtggt gtatatcggt gtatttctgc tcgatcgata ggaatattcc
     9121 ggcaagtgtc atctgtattt aaaggtcgtg tgagtatgaa atttatggaa tgtgctgtcc
     9181 gggatgtgat ttatgggacc aatgtccgta ttgtcaaacc ggtcaacatt tatgaatgtg
     9241 aactcaggga caatgtgttt gtcggcccct tcgttgagat acagaaaggc tgtgtcattg
     9301 gtagtggaag ccggatacag tcgcacacgt ttatttgtga gaacgtaaca ctgggggaga
     9361 actgcttcat tggtcataac gtgacgttcg ccaacgatct gtttcgttca ggagcaccag
     9421 atccgtcacc ggataactgg atcagcatta ccctggggga ttcggttact gttggcagtg
     9481 gagccattat tctgtctccg tatatatgca gcggagctgt tattggtgcg ggttcagttg
     9541 tggtaaaacc gattgagaac aaaggcattt atgcaggaaa cccggcaaga ctgctcagaa
     9601 tattatgaaa aagaaaaggg ccgttactgg ccctttttat cagaggtagg tctgtgaata
     9661 cggtaggtgt acagaaatcg actgccgggg atcgatttcc agggccgccc ggtattctgc
     9721 gtcagtgata tcaccttttt ttcagtaaat aaccgagagc atcgtttccc agccctgaca
     9781 gtatgcgtat tctggcgacc cggactggca aataacccat caaaaacgtt attgccagac
     9841 attgcgaact caccaatttt gattattgga gccacttttt cataagtttc gtgaaattat
     9901 ttcataataa cgaccatgtt tattttatgt aatgactggc aataaaataa cttgattaag
     9961 ttccctttat ccagcctgat agtggataaa ggaaactcaa tcataattta attagtttat
    10021 taacttcatc gcattctttt ttgtctcctc atcacttttt tgctccgatt gtgaagagga
    10081 ctgaatgatt gttgaagaat ttaaatcggc catctctttt ggaaatagcg atctcaatat
    10141 attcacgata tctgaaaatg tggtttcttt cgtcagcaat tcacataaaa ggaaaggggc
    10201 cctaggatct tgtctgtata aggccagacc tgccgtcagt gcagcccggt taaggcggct
    10261 gcgttcccct tgcgggatac tgtccagtgt atcacaaaca attttatctg tttgatttac
    10321 atctggattt agcttaaagg caatggttct gcgcttgtcc atcattaatt acctatgaga
    10381 tacataccgt taactaaatc atattgagag ttattggttt taaaaaaacg ttcatcacga
    10441 atctgtgtgt gtttttttac tgcatcgcat attaattctg cgccaccacc tataaccata
    10501 acatgagtat aaccagaaaa ttcattgagt gtatttaata cacgttgctc aagtttacga
    10561 agtgcttcat tcattgcttc ggtgactatt gatattttgt tctcatcatt aattcgttgc
    10621 ttcagatagt tattatcttt tctgtgaata attatatcgt cagcaagata gctacttcct
    10681 tttgttctcg caagagaaag ggcatctttt actgcagatg tgaccagaga tacaccaaga
    10741 gatgagtctc cgtatatttt actgatcccc gataatttcc ccattacctg agaaatatct
    10801 aatgtggtgc ccccgagatc tataattaat aaagaatcta actcatccag ttcttgtaga
    10861 acttcataac ctgccggtat agattcaggc atgactttta catcttttat tgtgaatgca
    10921 tccccaccat ttaatgtaat ttttttccgg aagtttgctt tcttacgctc aatattttcc
    10981 gtattgggtt ggttattcct gtcgtaatac tctgtcagag gaagtgtgca aacaatatcc
    11041 acttcgctta ccggcagacc actggtcagt aaggcgtggt gcaccgcaac gacattaacg
    11101 tcgctgtatt gccatgcgat attggttgtg actacagcat ccgggctgat tggatcaaat
    11161 gaatactgtt cgccgttcag tgtgtagtta aagacctttt tatcaccaaa agaaactgcc
    11221 cactcgcgtt tgaagctgtt cgggctaatg tgctgtttaa ttgttccgtc gttttcctgc
    11281 cactgtagtt tgatgtttgt tgaaccgtca tcaatgaata ccaacattta taaaactcct
    11341 tatggtgttt ttgtggtgtg cttttggggt tgctttgggt tttagatggg gtcgtttgtc
    11401 aagtttaccc cattttgact atcagtcaat gattgtttgt attgtttttg ggtttattat
    11461 ggtgtgtttt gggttgtttt tgggttttat ttggcgggta acaaaagatg tcgctgtgct
    11521 tctcttttta ctgcgccggc tgacgcggcg cggcaggaac gctgcctgtg gtcagtgtcc
    11581 cgcgtccggc cgggcacggg acgggcgctt ttaccgctcc tggctggcgt cggtgacagt
    11641 gtacgccagc ctgtcgccct tttctgatga atgcccttca agccgctttc gcggcatatc
    11701 ctcgccgtta gaaagacgac ggctgcggta ttccacggtc ggcctgaccc gttaccggac
    11761 gcggtgaaca gcccacaggc agcggagaac gggcgccaca ggggcgccct ccggtgccct
    11821 ctgtaagagg aggagtgctg ttatgtcccg ttttatcctg ggtgactgcg tgcgtgttat
    11881 ggccacgatt cctgataacg ccattgattt catcttaacc gacccaccat atctcgttgg
    11941 ttttcgtgac cgttccgggc gcaccattgc cggtgacgtt aacgatgact ggctgcaacc
    12001 tgccagtaat gagatgtacc gcgtactaaa aaaagatgcg ctgatggtga gtttctatgg
    12061 ctggaaccgt attgaccgct ttatggcagc ctggaaacgc gccggattca gcgttgtagg
    12121 gcaccttgtg ttcaccaaaa gctacacatc caaatctgcg tatgtcgcgt accgtcacga
    12181 atgcgcctat atcctggcaa aaggccgtcc ggcgctgcct ccgaagccat tacccgacgt
    12241 gctgggctgg aaatattcgg gcaaccgcca tcacccgacg gaaaagcctg ttaccagcct
    12301 gcaaccgctg attgagagct tcacacaccc gaacgcaatt gtgctggacc cgtttgctgg
    12361 cagcggctca acctgtgtgg ctgcccttca gtccggacgc cggtatatcg gtatcgagct
    12421 gcttgaacag tatcaccgtg ccggacagca acgactggcc accgtgcaac gggccatgca
    12481 gcagggggcc gcgaatgata actggtttga accggaggct gcgtaaatga actatgccgg
    12541 acacgaaaac ctggcggagg tggccaatgc catgtgtgac cttcgggcca ggctgaacga
    12601 tatggagcat cgctgtcgct ttgattccga tgtgctcgtc gaacgcctgg cacgccagac
    12661 gctgtatcgc gccaatcgcc tgttcatgga ggcatatacc gaaattcttg aactggatgc
    12721 gtgcttcaaa gattaagggg gagacgaaat gtacggaaca tgcgaaacgc tctgccggga
    12781 gctggaagca aagtatccgg gagacacgcc gctgatgctg gttatctggt ctccggaaga
    12841 gattcaggca ctggctgacg gtatggaaat ttctctgacc gatcatgaaa tcagggccgt
    12901 cctggcgcgc atggaggaca tcccggaaga ccagaggact gaatccggta tttcttccgc
    12961 cgcggtgatg gagattatca gcaacgtgag cgaaaaccgc caggtgaccg tccctgctga
    13021 actgctggcg tccctgattc agaccgctga acaggcactg tggaaacgtg agtgggccgc
    13081 ccgtgataac ggcctcgtcg tcccggaatg cgtcacccgc cgacaggcgg tggttaatca
    13141 ggcccgcgcc ctgctgaaaa acaacacacg cgaaaacgac tgatgttatc gccgcctgcg
    13201 ggcggcgatt cagggagacc atgaatcatg aacgaaacgc tgaatgcact gatttgtcgc
    13261 cacgcccgta acctgctgct ggcgcagggc tggccggaag agacggatgt tgaccagcga
    13321 aatccgaacc atccgggctg gatcagcatt tacgtgcggc tggatgcgcc ccggctggcg
    13381 acgttactta tcaaccgtca cggcggcgta ctgccgccgc acctggcctc tgccattcag
    13441 aaactgaccg gaaccggggc ggaacttgtt ctgtccggca gtcagtggca gtcgctgccg
    13501 gtacttccgg cagacggaac gcaggtgtct ttcccgtatg ccggtgagtg gctggcagaa
    13561 gacgaaatca gggctgtact tgcggcggtg cgcgatgcaa tacgaagcat ctgttaccag
    13621 gtggcagacg atgcgcggcg tatccgggcg gcgctgacca ccaccggtca gacgttgctg
    13681 acccgccaga cgcgccgctt tcgtctggtt gtgaaggaaa gcgatcaccc ctgctggctc
    13741 gatgaagatg acgaaaacct gcccgtggtg ctcgatgcca tcgtgaaccg gggagcacgt
    13801 ttttcgtcgg tggaaatgta cctggtcagc gattgtattg agcatatcct gtccagtggg
    13861 ctggcctgcg atgtgctgcg tataccggat gaaccgcccc gccgctggtt tgaccgtggt
    13921 gttctgcggg aggtggtccg ggaagcccgg gtagaaatcc gcagcatggc ggatgccctg
    13981 gcaaaaatca gggactaagg aagtcgccgc cggctccgct ttacccggcc atgcggggca
    14041 tggccttgtg ggttttcagt tatgtggccg ctgtgtcgtg tgcgggctgt gccgtgcctc
    14101 catcttagcc gggctggcag ggatgcaagg gtacgcttcg ccgctgcggt cacccggtcc
    14161 ctccttcccg tctgccgtga ttttccggtc gttcgcccgc tcaggtttcg cggcctcacc
    14221 ctgcaactcc cgccagccgt gtgcgtcagg ctgcggcttc ccttgcgccc ctgcatcccc
    14281 gccttatcgc ccggctttta tggaggcacg gcaccgcccg gtgtcgcgga atatgtgaac
    14341 aacggaggaa aacatcatgc aatatgcgaa acctgtcact ctgaacgttg aagagtgcga
    14401 ccgtctctcc tttctgcctt acctgtttgg caacgatttt ctgtatgccg aggcgtatgt
    14461 gtacgcgctg gcgcaaaaaa tgatgccgga atatcagggc ggcttctggc acttcatccg
    14521 cctgccggac ggtggcggtt acatgatgcc ggatggcgac cgtttccaca tggtgaacgg
    14581 tgcaaactgg tttgaccgta ccgtgagtgc tgatgccgca ggtgtcattc tgacttctct
    14641 tgtgattaac cgccagttgt ggctgtacca cgacagcggg gatgcaggac tgacccagct
    14701 ttaccggatg cgcgatgcgc agttgtggcg tcacatcgaa tttcaccccg aatgcaacgc
    14761 gatttacgcg gctctggact gattaacgga cggggcggca atgccgcccc tgtaaaggag
    14821 acgagaacat gtactgtact gttaaagaaa ttatccgcga agtgctggat acagacgtgc
    14881 cggacagtga atgcgttttt gccgtggtgc tgacccgtgg ggatgtgcgc catatggctc
    14941 aggactggag cctgtcagac gatgagctgg aaaccgtcat gcagcggctg gacgatgcct
    15001 ttgaatatgg tgcggatgtc agcgttgttc acggcgttgt tcgtgaactg atggaagaaa
    15061 agcgcgccag ccgtcaggtg acagtcccgg cggtgatgct ggaaaaagtg atggcgctgg
    15121 caggcagtga aatgaagcgc ctgtatgccg tcgggagtga gaatgggggc gacggtgacg
    15181 cattcgtcag ggaggaacgc gaagcaatgg acgttgtgtt acaggcgctg gacggggaga
    15241 cgatgtcatg aatatcagca cagaaagtcg cgaaattctg cgtaattaca gggccgtgat
    15301 taatgcgcgg cgtcgtgaaa tggggcagaa accgctcacc actgcgcaga ttgttgatga
    15361 aatctgcgat tttgtggcga atcagcaggc ggttttcctc ggtggtcact atatccttca
    15421 gggcagcaga aacaggtgat acagggcagg cggtggaggc cgcctgtcag cccgcgcgaa
    15481 aacccctggc aggctgacgc ctgccggaag ggaagcgggc cacgctggcg cgtcgcccgt
    15541 tacccttccc gtctgtgatg tgtctgactc aggagtgttt ctttcttatg ttatggaact
    15601 gttcctgatg ttgttgttcc tttatctgct gctctgattc tgactactgc agtgttgttc
    15661 tgtctgccgg gcgcaccttc ggctcccggc tgcctggcgg catccggtcg tcaggcccga
    15721 ctccgacagg cagctgctgg cgcacccgcc agtctccgcc gaacccgctg gcgcggtttc
    15781 gggctgtcgc tacggtccga tgcgtgaaaa ccccgggctt gcagcgaccg ttccggtcgc
    15841 gccacccttg tcgcgccgtg gcctgcgctc ccggcatccc ggcaaaaggc cgccgggatg
    15901 taaggggcaa cgccgtttcg cgcacgcgct ctccgtcgtt gcggcgggtc cctgctcatt
    15961 gcctgccggt gccacacacc cgtatgagtc cctgtcgccg ggggctgata cagccacaac
    16021 ctgccgcact gactgtccag ggtaaatgaa cagcccacaa aattttttac ccaaaacccg
    16081 gtaaaaaatt ttgcgttctg cccaggacag gtgcgtcagg ccgtggcagt gatgcccctt
    16141 gcggcgaagg ttctcaaacg ggtgaagttc ataccacagg gaatacagca gcaggttccc
    16201 gcgaaacgtc aaaaccgcgg ctcccgaaac tcaacgggtg atgttcttta aaaatcagga
    16261 tttatttcag gctccggcaa tacgcattta tgtgttctgt cagtcatccg gctggcaggt
    16321 aatgagaacg caggaacaga aggaggaaaa caccggagaa cgtcagacgc agatatgaaa
    16381 aaagcaggtc agggacctgc ttaatccaca ccgcagagac tgcacgaaca gtctttacgg
    16441 tttcattaat taacgtcata agaggctaaa ttatgacagt aagtattgtt tcaccttccg
    16501 cagcggctgt aaagccccgc cgtcatcccc gtttcagacg cgaagacatc cccgcgccgg
    16561 aaattgaccc cgtgctgaaa gccttcgggc gacacattgc ccggagtttt caccgggggc
    16621 gtggtgtaca catccccgcc atgaaaaaca cggccttcgg gcaggtgctc cgcacactcg
    16681 aactgaaacg cgcttttaac tgatgaggtg agccgccccg cgaggggcgg caacagacgg
    16741 aaggagaaca ttttatgaca tcagcagcaa tcaccatgac cgccccggaa gccgccagcc
    16801 ctgtgcagat gtaccgcgcg acctactcac cggatgacaa caaactgcgc ctgtatgccg
    16861 tgtcacgtct tgacccggag acgtataaaa aagtgcatga tgccggtttc cgctgggcac
    16921 caaaacaggc gctgtttgtc gcgccagcct ggacaccggg ccgggaagac gtgctcctct
    16981 cacttgccgg agagattgag gatgaagaca gcacgctcgc tgaacgtcag gaagcacggg
    17041 cggagcggtt taccggatac agcggaaagc gggccagtga atccgcacag gcacttgatg
    17101 aagtggaaag actggccgcg atgatcccgc ccggtcagcc cattcttgtg gggcatcaca
    17161 gcgaacgccg cgcccgtcgt gatgcgcagc gtattgaaaa cggcatgaaa cgagccgtga
    17221 tgctctttga acgtgcg
//
