LOCUS       CP056941.1             17235 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CP056941.1 Escherichia coli strain RHB42-C04 plasmid pRHB42-C04_2,
            complete sequence.
ACCESSION   CP056941
VERSION     CP056941.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 18:04:14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17235
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..858
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSRF
                     DFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECGLA
                     TESAAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDVSEE
                     AVAAARRSRVEWENRQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIKRARA
                     RRDANRERQDIVTLVKRQLTREIAEGRFTASREAVKREVERRVKERMILSRNRNYSRLA
                     TASP"
     protocluster    1..17235
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5245:7235]"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5246..7235
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
     cand_cluster    1..17235
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /kind="single"
                     /product="LAP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17235
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="LAP"
                     /region_number="1"
                     /rules="((((goadsporin_like or PF00881 or TIGR03605) and
                     (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or
                     TIGR03602) and not cyanobactin_synth)"
                     /tool="antismash"
     CDS             1791..2675
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MDLYHFTAIPMLHSILASEGLREGYLTLYDGTILYNKVWLTTSPL
                     PYGHGLCNGTEKLSESEKSFMRRVGNISESTSINGTHNKKLIRLKIDTEWIKKQPGFCS
                     YKKLMRDLGQPKAYVKYVGAMGVEGARGMTDEQISKIMRKGNTKEDTWYIFNGVIPPSK
                     IVSVEYMETKDKYIPYDFELHGRGYIENSGIYPISNLLLSDLNHTMRNITFLPGSVIAF
                     CHKANSEENILFRHVLFTCSISLRNFSVLIATGDETSFYIHLDVLKSWTQKNSKVLCQL
                     FEKARESYHRYYG"
     CDS             complement(3216..3779)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MDIIEKRITKRHLSESELSGVNYYNCIFERIQLDNFNFRDCEFEK
                     CRFVNCSIKNLKLNFFKLIDCEFKDCLLQGVNAADIMFPCTFSLVNCDLRFVDFISLRL
                     QKSIFLSCRFRDCLFEETDLRKSDFTGSEFNNTEFRHSDLSHCDFSMTEGLDINPEINR
                     ILSIKIPQEAGLKILKRMGVVVGG"
     CDS             complement(3783..4514)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 95.1; E-value:
                     9.3e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MTIPLLEINSLSFSYKVNLPPVFNNLSLKIEQGELIGLLGENGAG
                     KTTLFNLIRGGVSNYEGTLKRNFSGGELVSLPQVINLSGTLRNEEVLDLICCFNKLTKK
                     QAWTELNHKWNDNFFIRYDKIRRKRTYTVSYGEKRWLIISLMLTLCKNARLFLLDEPTV
                     GIDIQYRMMLWELINKITADGKTVFFSTHIFDELTRDKIPFYMLSKNSINRYSDMSDFI
                     QSNNETTPEKAFIKEVMGTGD"
     CDS             complement(4511..5236)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MVTLKMAIIFLMEQIRTPFSLIWTIMSPTVLFFFLHFNEIELHYG
                     DTAWLGKQISWFVGYISFSVVLFNYCLYLVGRRESGFIATFVHNMDGRLLFIRSQLIAS
                     LIMSILYVFFFILVVLTGFQASPDYQIVMIILKSIYINAFMMVSLTFMASFRVAFQTAS
                     TIYSVLITVCMVSGIVSLKYNEGIVYWINQVNPIAIYSTILQSDQELSLMTIFFYSIML
                     IISIISALTFKTEPVWSSQ"
     CDS             complement(5246..6436)
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_6"
                     /sec_met_domain="YcaO (E-value: 1e-16, bitscore: 53.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVYSNLMSAWPATMAMSPKLNRNMPTFSQIWDYERITPASAAG
                     ETLKSIQGAIGEYFERRHFFNEIVTGGQKTLYEMMPPSAAKAFTEAFFQISSLTRDEII
                     THKFKTVRAFNLFSLEQQEIPAVIIALDNITAADDLKFYPDRDTCGCSFHGSLNDAIEG
                     SLCEFMERQSLLLYWLQGKANTEISSEIVTGINHIDEILLALRSEGDIRIFDITLPGAP
                     GHAVLTLYGTKNKISRIKYSTGLSYANSLKKALCKSVVELWQSYICLHNFLIGGYTDDD
                     IIDSYQRHFMSCNKYESFTDLCENTVLLSDDVKLTLEENITSDTNLLNYLQQISDNIFV
                     YYARERVSNSLVWYTKIVSPDFFLHMNNSGAININNKIYHTGDGIKVRESKMVPFP"
     CDS             complement(6417..7235)
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7"
                     /sec_met_domain="PF00881 (E-value: 8.4e-10, bitscore: 31.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKHELSLVEVTHYTDPEVLAIVKDFHVRGNFASLPEFAERTFVS
                     AVPLAHLEKFENKEVLFRPGFSSVINISSSHNFSRERLPSGINFCDKNKLSIRTIEKLL
                     VNAFSSPDPGSVRRPYPSGGALYPIEVFLCRLSENTENWQAGTNVYHYLPLSQALEPVA
                     TCNTQSLYRSLSGGDSERLGKPHFALVYCIIFEKALFKYRYRGYRMALMETGSMYQNAV
                     LVADQIGLKNRVWAGYTDSYVAKTMNLDQRTVAPLIVQFFGDVNDDKCLQ"
     CDS             complement(7237..8091)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04424"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_8"
                     /sec_met_domain="TIGR04424 (E-value: 7.3e-88, bitscore:
                     287.1, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINILPFEIISRNTKTLLITYISSVDITHEGMKKVLESLRSKQGI
                     ISEYLLDKLLDESLIDKDKGKEFLITTGVINKTKTSPLWVNSVIISDVPHLFSNAREQW
                     KSDGVFVSHIIDIKDNNINVSDSTLIWLHLENYHSDIVKRIYSKFESNPGVAFIQSYYL
                     KESFRIDGVYSPDLGTPCHFCHIERWLSREEKSFRRNEMSWANLLQLLKKYQMTLPALA
                     LGESERGFSYHLIKRRLQELTGTSLVKSHVDNFMSSVSADLITSILCKEPVIHWQACSC
                     LER"
     CDS             complement(8151..8351)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MELKASEFGVVLSVDALKLSRQSPLGVGIGGGGGGGSCGGQGGGC
                     GGCSNGCSGGNGGSGGSGSHI"
     CDS             8806..9102
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MIQTRNQYLQFMLVMLAAWGISWGARFVMEQAVLLYGPGKNYLFF
                     SHGAVLMYLLCVFLVYRRWIAPLPVVGQLRNVGVLCLVGAMAVVYIGVFLLDR"
     CDS             9117..9599
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MSSVFKGRVSMKFMECAVRDVIYGTNVRIVKPVNIYECELRDNVF
                     VGPFVEIQKGCVIGSGSRIQSHTFICENVTLGENCFIGHNVTFANDLFRSGAPDPSPDN
                     WISITLGDSVTVGSGAIILSPYICSGAVIGAGSVVVKPIENKGIYAGNPARLLRIL"
     CDS             complement(10003..10356)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MMDKRRTIAFKLNPDVNQTDKIVCDTLDSIPQGERSRLNRAALTA
                     GLALYRQDPRAPFLLCELLTKETTFSDIVNILRSLFPKEMADLNSSTIIQSSSQSEQKS
                     DEETKKNAMKLIN"
     CDS             complement(10356..11318)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MLVFIDDGSTNIKLQWQESDGTIKQHISPNSFKREWAVSFGDKKV
                     FNYTLNGEQYSFDPISPDAVVTTNIAWQYSDVNVVAVHHALLTSGLPVSEVDIVCTLPL
                     TEYYDRNNQPNTENIERKKANFRKKITLNGGDAFTIKDVKVMPESIPAGYEVLQELDEL
                     DSLLIIDLGGTTLDISQVMGKLSGISKIYGDSSLGVSLVTSAVKDALSLARTKGSSYLA
                     DDIIIHRKDNNYLKQRINDENKISIVTEAMNEALRKLEQRVLNTLNEFSGYTHVMVIGG
                     GAELICDAVKKHTQIRDERFFKTNNSQYDLVNGMYLIGN"
     CDS             11836..12519
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MSRFILGDCVRVMATFPGNAVDFILTDPPYLVGFRDRSGRTIAGD
                     KTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMSAWKNAGFSVVGHLVFTKNYTSK
                     AAYVGYRHECAYILAKGRPALPQKPLPDVLGWIYSGNRHHPTEKPVTSLQPLIESFTHP
                     NAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLTAVQRAMQQGAANDNWF
                     EPEAA"
     CDS             12520..12741
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MNYAGHENLRAEVAEVANAMCDLRARLNDMEHRCRFDSDVLVERL
                     ARQTLYRANRLFMEAYTEILELDSCFKD"
     CDS             12755..13189
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MYGTCETLCRALAAKYPGDTPLMLVIWSPEEIQALADGMEISLTD
                     HEIRTVLARLEDIPEDQRIESGISSAAAMEIISNVSENRQVTVPAELLASLIQTAEQAL
                     WKREWAARDHGLAVPECVTRRQAVVNQARTLLKNNTREND"
     CDS             13234..14004
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MNETLNALICRHARNLLLAQGWPEETDVDQRNPNYPGWISIYVRL
                     DAPRLATLLINRHGGVLPPLLASAIQRLTGTGAELVLSGSQWQSLPVLPADGTQVSFPY
                     AGEWLTEDEIRAVLDAVHDAVRSICYQVAEDARRIRAALTTTGQTLLTRQTRRFRLVVK
                     ESDHPCWLDEDDENLPVVLDAIVNRGARFSSVEMYLVSDCIEHILSCGLACDVLRIPDE
                     PPRRWFDRGVLREVVREARAEIRSMADALAKIRK"
     CDS             14422..14847
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MQYAKPVTLNVEECDRLFFLPYLFGQDFLYVEASVYALAKKMMPE
                     YEGGFWHFIRLPDGGGYMMPDGDRFHLVNGENWFDRTVSADAAGVILTSLVINRQLWLY
                     HDSGNAGLTHLYRMRDAQLWSHIEFHPECNAIYAALD"
     CDS             14894..15316
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MYCTVKEIIREVLDTDVPDSECVFAVVLTRGDVRHIAQDWNLSDD
                     ELETVMQRLDDAFEHGADVSIVHDVVRELMAEKRASRQVTVPAVMLEKVMALAGSEMKR
                     LYAVGSENGGDGDAFVREEREAMDVVLQALDGEHMS"
     CDS             15313..15504
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MNISTETREILRNYKAVINARRREMGQKPLTTAQIVDEICDFVAN
                     QQAVFLGGHYILQGSRNR"
     CDS             16499..16729
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIARS
                     FHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
ORIGIN
        1 gtgactgatc ttcaacaaac gtattaccgc caggtaaaga acccgaatcc ggtgtttaca
       61 ccccgtaaag gtgccggaac gctgaagttt tgcgaaaaac tgatggaaaa ggcggtgggc
      121 ttcacctccc gttttgattt cgccattcat gtggcgcatg cccgttcgcg tggtctgcgt
      181 cgacgcatgc caccggtgct gcgtcgacgg gctattgatg cgctgctgca ggggctgtgt
      241 ttccactatg acccgctggc caaccgtgtc cagtgctcca tcaccacgct ggccattgag
      301 tgcgggctgg cgacggagtc tgctgccgga aaactctcca tcacccgtgc cacccgggct
      361 ctgacgttcc tgtcagagct gggactgatt acctaccaga cggaatatga cccgcttatc
      421 gggtgctaca ttccgaccga tatcacgttc acatctgcac tgtttgctgc cctcgatgta
      481 tcagaggagg cagtggccgc cgcgcgccgc agccgtgtgg aatgggaaaa cagacagcgc
      541 aaaaagcagg ggctggatac cctgggtatg gatgagctga tagcgaaagc ctggcgtttt
      601 gtgcgtgagc gtttccgcag ttaccagaca gagcttaagt cccggggaat aaagcgtgcc
      661 cgtgcgcgtc gtgatgcgaa cagggaacgt caggatatcg tcaccctggt gaaacggcag
      721 ctgacgcgcg aaatcgcgga agggcgcttc actgccagtc gtgaggcggt aaaacgtgaa
      781 gtggagcgtc gtgtgaagga gcgcatgatt ctgtcacgta accgtaatta cagccggctg
      841 gccactgcct ccccctgagt tttacctcat ctgaataatc cggcctgcgc cggaggcatc
      901 tgcacgcctg aagcctgtca gcgaacaaaa aaacagcacc acatacaaaa aacaatctca
      961 tcatcccgct tctggtgcat ccggcccccc tgttttcgat acaaaacatg cctcacagac
     1021 gtggaatttt gcttatccac atttaactgc aagggacttc cccataaggt tacaaccgtt
     1081 catgtcataa agcgccagcc gtcagcgtta cagggtgcaa tgtatctttt aaacacctgt
     1141 ttatatctcc tttaaactac ttaattacat tcatttaaaa agaaaaccta ttcattgcct
     1201 gtcctgtgga cagacagata tgcacctccc accgcaagcg gcgggcccca accggagcca
     1261 ttttagttac aacactcaaa tcaaccaccg ggaaaactcc ggtccagcgc agaaccgaaa
     1321 ccacaaagcc cctccctcat aactgaaaag cggccccgcc ccggcccgaa gggccggaac
     1381 agagtcgctt ttaattatga atgttgtaac taatagtcgt catcgctgtc agtcttctgg
     1441 cgggaagtcc tcagtacacg ctcgtaagcg gccctcacgg cccgctaacg cggagatacg
     1501 ccccgacttc gggtaaaccc tcgtcgggac cactccgacc gcgcacagaa gctctctcat
     1561 ggctgaaagc gggtatggtc tggcagggct ggggatgggt aaggtgaaat ctatcaatcc
     1621 gtaccggctt acgccgggct tcggcggttt tactccggta tcacatgtaa ccacagcgtg
     1681 ccgccttaca tgccgctgaa gcggcattca gtagacaggc tatgcacgac tcgccagtct
     1741 ggcctgaaca tgatataaaa tgaatataaa tagacagaat agggttattt atggatttat
     1801 atcactttac agcaattcct atgttgcatt ccatacttgc atctgaaggc ctgagagaag
     1861 gatatctaac gttgtatgat ggaacaattt tgtataataa agtatggtta acgacatctc
     1921 cattaccata tggtcacgga ttatgtaacg gtactgaaaa attaagtgaa tcagaaaaat
     1981 catttatgcg aagagtcggt aatatatctg agtctacgtc tataaatgga acacataata
     2041 aaaagttaat aaggttaaaa atagatactg aatggataaa aaagcagcct ggattttgct
     2101 catataaaaa gctgatgcgt gaccttggac aacctaaagc ttatgttaag tacgtaggtg
     2161 caatgggggt tgagggggca agggggatga ccgatgagca gataagtaaa attatgcgaa
     2221 aaggtaacac aaaagaagat acctggtata tctttaatgg ggtcatccca ccttcaaaaa
     2281 tagtctctgt tgaatatatg gaaactaaag ataaatatat accatatgat tttgaattgc
     2341 atggaagggg atatatagaa aactccggca tttatccgat ttcgaattta ttattatctg
     2401 atctgaatca tacaatgcga aatattacat ttttaccagg ttctgtcata gcgttttgtc
     2461 ataaagcaaa ttcagaagaa aatattttat tcagacatgt attattcaca tgttcaatct
     2521 ccttgagaaa tttttcagta ctgatagcaa caggtgatga gacatctttc tatattcatc
     2581 tggatgtatt aaaaagttgg actcaaaaaa acagtaaagt actatgccaa ctttttgaaa
     2641 aagcacgtga aagttaccac agatactatg gttagaaacc actgcgggga gaacatcagt
     2701 ggcacaaaac tagaccgccc ggaaccggga cgcttactga tggacagtca tcgcaatgat
     2761 atcttgctgg ttgagcagat aggggctccg tgggaatttc tgcgataaca cccgctaagc
     2821 gatttctccc tgacggaaat cacttgtttt tcgttcagag gcaggcaaga ggaatattca
     2881 tccccaaaaa cggcgttttc atatgcggaa aacgctgccg gatagtcgaa tagtacgaca
     2941 aactgacttc tgacgttttc cgtacatttc agattcagta accccgaata tttggggttg
     3001 gtatggctaa cgccttgaat ttcaatgaac aatattttgt taccgtgtac tgtcgcagaa
     3061 atgcccacgg aaccccgaga tggagaactc agtcaatgtt ccattctttc tgaaatatgt
     3121 gtggggacac tgatctgtcg ggagccggat gcggtagttc cgcaggtccg gttctgagga
     3181 ggggcccgtc cgggcaaccg gcgggtctac tcacctcatc cccctacaac cactcccatt
     3241 cgtttaagta tttttaaacc tgcttcctgt ggtatcttta tagataagat cctgtttatc
     3301 tcaggattta tatcgagacc ttctgtcatt gaaaaatcac agtgagacaa atcagaatgt
     3361 ctgaactctg tattattaaa ctccgaacca gtaaaatcag atttacgaag gtctgtttcc
     3421 tcaaataaac aatcacggaa gcgacaggat aaaaaaatag atttctgtaa ccgtaaacta
     3481 ataaaatcaa caaatctcaa atcacaattt acaagagaaa aagtacaggg aaacataatg
     3541 tctgctgcat ttactccttg taataaacaa tctttgaatt cacagtcaat aagtttaaaa
     3601 aaattaagtt ttaaattctt tattgagcag tttacgaagc gacatttttc gaactcacaa
     3661 tcgcgaaagt taaagttgtc aagctgtatt cgttcaaata tacaattgta ataatttaca
     3721 cctgataatt cactttcact gaggtgtcgt tttgtgattc ttttttctat tatatccatg
     3781 tgtcagtctc ctgttcccat aacttcttta ataaatgcct tttctggagt tgtttcatta
     3841 ttggattgaa taaaatcact catatcagaa taacgattta tactattttt tgaaagcata
     3901 tagaagggga ttttatctct tgttaattca tcaaaaatat gagttgagaa aaataccgtt
     3961 ttcccgtcag cggtgatctt atttatcagt tcccataaca tcattctgta ctgaatatca
     4021 atgcctacag ttggttcatc cagtaaaaat aaacgggcat ttttgcaaag cgttagcatc
     4081 aaagatatga taagccaacg cttctctcca taacttaccg tgtaagtcct tttacgtctt
     4141 attttatcat agcgaataaa aaaattatca ttccatttat gattaagctc tgtccatgcc
     4201 tgttttttag ttaacttatt gaagcagcaa atcaaatcaa gaacctcctc attccttagt
     4261 gtacctgaaa gatttatgac ttgaggtaga cttactaatt ctccaccaga gaaatttcgc
     4321 ttgagggtcc cttcataatt actgactccg cccctgataa ggttaaaaag agtggtcttc
     4381 ccggctccat tttctccaag cagacctatc aactctccct gctcaatctt aagcgacaga
     4441 ttattgaaaa cagggggtaa atttacttta tatgaaaagc tcagagagtt gatttctaaa
     4501 agaggtatgg tcattgagaa ctccagactg gctcagtttt gaaggttagt gctgaaataa
     4561 tacttatgat taacattata ctatagaaaa atatcgtcat cagagacaac tcctggtctg
     4621 actggagtat tgtagaatag atggcgatag gattaacctg atttatccag taaacgatcc
     4681 cctcattata ttttaatgat acaattcctg ataccataca gacagttatt aatacagaat
     4741 agatagtgct ggctgtttgg aatgcgactc tgaacgatgc catgaaagtg agtgaaacca
     4801 tcataaatgc atttatgtat atcgatttta aaataatcat tactatttga taatctggac
     4861 ttgcctggaa tcctgttagt acgactaaaa tgaaaaaaaa cacatacaaa atagacatga
     4921 taagtgaggc tattaattga gaacgaataa ataatagtcg accatccata ttatgcacga
     4981 aggtagcaat aaaaccactt tctcttcttc cgaccagata cagacagtaa ttaaacagaa
     5041 caacagaaaa agaaatgtag cctacaaacc atgatatttg ttttccgagc catgctgtat
     5101 caccataatg aagttcaatt tcattgaaat gaaggaaaaa gaacaacact gtaggtgaca
     5161 taattgtcca tattaagctg aaaggggttc tgatttgttc catcagaaaa attatcgcca
     5221 tttttaatgt aaccatttgt tatccttatg ggaatggtac catctttgat tctctgactt
     5281 taataccgtc cccggtatgg taaattttat tattaatgtt tattgcacct gagttattca
     5341 tatgaaggaa aaaatcaggg cttactattt ttgtgtacca gacaaggctg ttacttactc
     5401 tttccctggc atagtaaaca aaaatattat cagaaatttg ttgaagatag tttaataaat
     5461 ttgtgtctga cgtaatattt tcctcaagcg ttaacttgac atcatcagac agtagtaccg
     5521 tattttcaca caaatccgta aacgactcgt acttgttgca tgacataaag tgacgctggt
     5581 aactatcaat aatgtcatca tcagtataac cgccaataag aaagttgtgc aggcatatat
     5641 acgattgcca caattccact acggatttac aaagtgcttt tttcagacta ttagcatagg
     5701 ataatccggt actgtatttt attcgactga ttttgttttt tgtgccatac agggttagta
     5761 ctgcgtgtcc aggagctccg ggcagggtga tatcgaaaat cctgatatct ccttctgacc
     5821 tgagagccag taaaatctca tctatatgat ttatgcctgt tactatttca ctggatattt
     5881 cagtattggc ttttccctgt aaccagtaaa gaaggaggga ctgtctctcc ataaattcac
     5941 acaaggaacc ttctatggca tcgttcaaac taccatgaaa gctacatccg catgtatctc
     6001 tgtcaggata aaatttcaga tcatctgcag cggttatatt gtcgagtgca attatgactg
     6061 caggtatttc ttgttgttca aggctaaaca gattaaaggc tctgaccgtt ttaaatttat
     6121 gggttatgat ttcatcgcgg gtcagtgatg agatctgaaa aaatgcttcg gtaaaagcct
     6181 ttgcagcaga tggaggcatc atctcatata atgttttctg accaccggtg actatctcat
     6241 taaaaaaatg acggcgttca aaatattcac ctattgcccc ctgaattgac ttcagagttt
     6301 caccggccgc gctggctggt gtaatacgct catagtccca tatctgagaa aacgttggca
     6361 tatttctgtt cagttttgga ctcatggcca ttgtggccgg ccatgcggac ataaggttac
     6421 tgtagacatt tatcatcgtt tacatctcca aaaaactgaa cgatcagtgg cgctacggtc
     6481 ctctgatcca gattcattgt ttttgctacg tatgaatcgg tatatcccgc ccatacccgg
     6541 tttttcagtc ctatttgatc tgcaaccaat actgcgttct gatacatcga acctgtttcc
     6601 attaaggcca tccggtatcc tctgtagcga tatttgaaca aagctttttc aaaaataatg
     6661 caatagacga gagcaaaatg gggtttacca agacgttccg aatccccacc ggacaggctt
     6721 cggtagagtg actgagtatt acatgtagca acaggttcca gtgcctgact tagcggcagg
     6781 tagtgataaa cattagttcc tgcctgccag ttttctgtat tttcagataa tctgcataaa
     6841 aaaacttcaa tcgggtacaa tgccccccca gaaggataag gtcttcttac agagccagga
     6901 tcaggtgagc tgaatgcatt gactaataac ttttcaatag tacgaatgga aagtttattt
     6961 ttgtcgcaaa agtttattcc tgatgggagc ctttcacgac taaaattatg tgatgaggat
     7021 atgtttatta cggagctgaa acctggcctg aagagaactt ctttattttc aaatttctcc
     7081 agatgggcaa gaggtaccgc ggacacgaaa gttcgttcag caaattcggg gagggaagca
     7141 aagttacctc tgacatgaaa atctttaaca atggccagaa cttcaggatc tgtgtaatgc
     7201 gttacttcca ctaaagagag ttcgtgtttt gacatgttat ctctccagac agctgcaagc
     7261 ctgccagtga attaccggct ctttacataa aatactggtg attaaatcag cgctaacaga
     7321 tgacataaag ttatcgacat gacttttaac cagtgaagta cctgtcaact cctgaagtcg
     7381 ccgttttatt aaatgatagc tgaatcctct ttctgattcg cctaaagcca atgctggtag
     7441 tgtcatttgg tattttttca gtaactgaag taagtttgcc caggacattt cgttacgtct
     7501 gaagcttttt tcttccctgc tcagccatct ctctatatga caaaaatggc agggagtacc
     7561 aagatcaggt gaatatactc catctatcct gaatgactcc tttaggtagt agctttggat
     7621 gaaggcaaca ccagggttac tttcaaattt tgaatagatt ctttttacaa tgtctgaatg
     7681 atagttttcg agatgtaacc agattagtgt tgaatcgctc acattaatat tattatcttt
     7741 tatatcaatg atatgagaaa caaaaacacc atcagatttc cattgttccc gggcattact
     7801 gaaaagatgt ggaacatcgc ttattatgac tgagtttacc cagagaggtg atgttttcgt
     7861 tttatttatc acgcctgtgg taataagaaa ctctttgccc ttgtctttat caataagcga
     7921 ttcgtccagt agtttatcaa ggaggtattc agaaataata ccctgtttgg atcgtaggct
     7981 ttcgagtact tttttcattc cctcatgtgt aatgtctact gaagaaatgt aggtaataag
     8041 cagggtcttt gtatttctgg aaattatctc aaatggcaga atattgatca tatcttttcc
     8101 ttttttaata tcagggagca ccatgctccc tgaacggtta attcaacgta tcagatatgt
     8161 gaaccacttc cgccgctgcc accgtttcca ccactacaac cgttgctgca accaccacaa
     8221 ccgccacctt gaccaccgca gctaccgccg ccgccaccgc caccaatgcc aacacctaat
     8281 ggagactggc gtgataattt aagagcatca acggacaaaa ctacaccaaa ttcactcgct
     8341 tttaattcca taaggactcc ttttttaagg gaaattaatg cttatgacat ctgaatagta
     8401 tgttggccaa cactagttac ttgccgtaat taactatatt ttgcaatgat aatttgaact
     8461 aaatttgtac gcctgttaaa tgtttaatag taatatcagt tagttgtgtt tatgtagtta
     8521 ttgatttttt acaaaaatta atattgtgtt tacattttgc tttcagttgc tgtcaggatg
     8581 tcacactacc cctttaagcc cccactggtc tggcagggcc gggggtgggt aaggggaaac
     8641 ctgtcaatca gtaccggctt acgccggtat catatgcaac aactgagtgc cgccttccat
     8701 gccgctggtg cggcatatcc tggtgacgat atctgaattg ttatagatat gtatatacgt
     8761 agtaatgaca agaataggat aagttaaaaa tttacaggag atgcaatgat tcagacacgt
     8821 aatcaatatc tgcagtttat gctggttatg ctggctgcat ggggcattag ctggggagcc
     8881 agatttgtca tggagcaggc cgttctgctt tatgggccag gaaaaaacta tttgttcttc
     8941 agtcatggtg ctgttctgat gtacctgctg tgtgttttcc tggtataccg ccgttggata
     9001 gctccgctac cggtcgttgg tcagctgcgc aacgttggcg tactgtgtct ggtcggtgcg
     9061 atggccgtgg tgtatatcgg tgtatttctg ctcgatcgat aggaatattc cggcaagtgt
     9121 catctgtatt taaaggtcgt gtgagtatga aatttatgga atgtgctgtc cgggatgtga
     9181 tttatgggac caatgtccgt attgtcaaac cggtcaacat ttatgaatgt gaactcaggg
     9241 acaatgtgtt tgtcggcccc ttcgttgaga tacagaaagg ctgtgtcatt ggtagtggaa
     9301 gccggataca gtcgcacacg tttatttgtg agaacgtaac actgggggag aactgcttca
     9361 ttggtcataa cgtgacgttc gccaacgatc tgtttcgttc aggagcacca gatccgtcac
     9421 cggataactg gatcagcatt accctggggg attcggttac tgttggcagt ggagccatta
     9481 ttctgtctcc gtatatatgc agcggagctg ttattggtgc gggttcagtt gtggtaaaac
     9541 cgattgagaa caaaggcatt tatgcaggaa acccggcaag actgctcaga atattatgaa
     9601 aaagaaaagg gccgttactg gcccttttta tcagaggtag gtctgtgaat acggtaggtg
     9661 tacagaaatc gactgccggg gatcgatttc cagggccgcc cggtattctg cgtcagtgat
     9721 atcacctttt tttcagtaaa taaccgagag catcgtttcc cagccctgac agtatgcgta
     9781 ttctggcgac ccggactggc aaataaccca tcaaaaacgt tattgccaga cattgcgaac
     9841 tcaccaattt tgattattgg agccactttt tcataagttc cgtgaaatta tttcataata
     9901 acgaccatgt ttattttatg taatgactgg caataaaata acttgattaa gttcccttta
     9961 tccagcctga tagtggataa aggaaactca atcataattt aattagttta ttaacttcat
    10021 cgcattcttt tttgtctcct catcactttt ttgctccgat tgtgaagagg actgaatgat
    10081 tgttgaagaa tttaaatcgg ccatctcttt tggaaatagc gatctcaata tattcacgat
    10141 atctgaaaat gtggtttctt tcgtcagcaa ttcacataaa aggaaagggg ccctgggatc
    10201 ttgtctgtat aaggccagac ctgccgtcag tgcagcccgg ttaaggcggc tgcgttcccc
    10261 ttgcgggata ctgtccagtg tatcacaaac aattttatct gtttgattta catctggatt
    10321 tagcttaaag gcaatggttc tgcgcttgtc catcattaat tacctatgag atacataccg
    10381 ttaactaaat catattgaga gttattggtt ttaaaaaaac gttcatcacg aatctgtgtg
    10441 tgttttttta ctgcatcgca tattaattct gcgccaccac ctataaccat aacatgagta
    10501 taaccagaaa attcattgag tgtatttaat acacgttgct caagtttacg aagtgcttca
    10561 ttcattgctt cggtgactat tgatattttg ttctcatcat taattcgttg cttcagatag
    10621 ttattatctt ttctgtgaat aattatatcg tcagcaagat agctacttcc ttttgttctc
    10681 gcaagagaaa gggcatcttt tactgcagat gtgaccagag atacaccaag agatgagtct
    10741 ccgtatattt tactgatccc cgataatttc cccattacct gagaaatatc taatgtggtg
    10801 cccccgagat ctataattaa taaagaatct aactcatcca gttcttgtag aacttcataa
    10861 cctgccggta tagattcagg catgactttt acatctttta ttgtgaacgc atccccacca
    10921 tttaatgtaa tttttttccg gaagtttgct ttcttacgct caatattttc cgtattgggt
    10981 tggttattcc tgtcgtaata ctctgtcaga ggaagtgtgc aaacaatatc cacttcactt
    11041 accggcaggc cactggtcag taaggcgtgg tgcaccgcaa cgacattaac gtcgctgtat
    11101 tgccatgcga tattggttgt gactacagca tccgggctga ttggatcaaa tgaatactgt
    11161 tcgccgttca gtgtgtagtt aaagaccttt ttatcaccaa aagaaactgc ccactcgcgt
    11221 ttgaagctgt tcgggctaat gtgctgttta attgttccgt cgctttcctg ccactgtagt
    11281 ttgatgtttg ttgaaccgtc atcaatgaat accaacattt ataaaactcc ttatggtgtt
    11341 ttttttggtg tttgtttggg tgtgttttgg gttttaagtg ggtttatttg tcaagtttac
    11401 cccattttaa ctatcaatca atgattattt gtcttgtttt ggtgttttat tgggtttggc
    11461 gtgggttgtt tttgggtttt gtttggcgga taacaaaaga tgtcgccggg ctcctctttt
    11521 tactgcgccg gctgacgcgg cgcggcagga acgctgcctg tggtcagtgt cccgcgtccg
    11581 gccgggcacg ggacgggcgc ttttaccgct cccggctggc gtcggtgaca gtgtacgcca
    11641 gctcgtcgcc cttttctgat gagcgccctt caagccgctt tcgcggcata gccttgccgt
    11701 caaaaagacg acggctgcgg tattccacgg tcggcctgac ccgttaccgg acgcggtgaa
    11761 cagcccacag gcagcgggga acgggcacca caggggtgcc ctcccggtgt cctctgtaag
    11821 agaaggagtg ctgttatgtc ccgttttatc ctgggtgact gcgtgcgtgt tatggccacg
    11881 tttccgggca atgctgtcga tttcatcctc accgacccgc cgtatctcgt cggtttccgt
    11941 gaccgttccg ggcgcaccat cgctggcgat aaaaccgatg aatggctgca accggcctgt
    12001 aatgaaatgt accgcgtgct gaaaaaggac gcgctgatgg tgagcttcta tggctggaac
    12061 cgcgtcgatc gctttatgtc tgcctggaaa aatgcgggat tcagtgtggt cgggcacctg
    12121 gtcttcacca aaaactacac atcgaaggcc gcatatgtgg gctatcgcca cgaatgcgct
    12181 tacatcctgg caaaagggcg tccggcgctg cctcagaagc cattacccga cgtgctgggc
    12241 tggatatatt caggcaatcg tcatcacccg actgaaaagc ctgttaccag cctgcaacca
    12301 ctgattgaga gcttcacaca tccgaacgcg attgtgctgg acccgtttgc aggcagcggc
    12361 tcaacctgtg tggccgccct tcagtccgga cgccggtata tcggtatcga gctgcttgaa
    12421 cagtatcacc gtgccggaca gcaacgactg accgccgtgc aacgggccat gcagcagggg
    12481 gccgcgaatg ataactggtt tgaaccggag gctgcgtaaa tgaactatgc cggacacgaa
    12541 aaccttcgcg ctgaagtggc ggaagtggcc aatgccatgt gtgaccttcg ggccaggctg
    12601 aacgatatgg agcatcgctg tcgctttgat tccgatgtgc tcgttgaacg cctggcacgc
    12661 cagacgctgt atcgcgccaa tcgcctgttc atggaggcat ataccgaaat tctggaactg
    12721 gattcctgct tcaaagattg agaaggagac gagaatgtac ggaacatgcg aaacgctatg
    12781 ccgggcgctg gcagcaaagt atccgggaga cacgccgctg atgctggtta tctggtcccc
    12841 ggaagagatt caggcactgg ctgacggtat ggaaatttct ctgaccgatc atgaaatcag
    12901 gaccgtcctg gcgcgcctgg aggacatccc ggaagaccag cgaattgagt ccggtatttc
    12961 ttccgccgcg gcgatggaga ttatcagcaa cgtgagcgaa aaccgccagg tgaccgttcc
    13021 ggctgaactg ctggcgtccc tgattcagac cgctgaacag gcattgtgga aacgtgaatg
    13081 ggccgcccgg gatcatggcc tcgccgtccc ggaatgcgtc acccgccgtc aggcggtggt
    13141 taatcaggcc cgcaccctgc tgaaaaacaa cacacgcgaa aacgactgat gttatcgccg
    13201 cctgcgggcg gcgattcagg gagaccatga atcatgaacg aaacgctgaa tgcactgatt
    13261 tgtcgccacg cccgtaacct gctgctggcg cagggctggc cggaagagac ggatgttgac
    13321 cagcgaaatc cgaactatcc gggctggatc agcatttacg tgcggctgga tgcgccccgg
    13381 ctggcgacgt tacttatcaa ccgtcacggc ggcgtactgc cgccgctcct ggcctccgcc
    13441 attcagagac tgaccggaac cggagcggaa ctggtactgt ccggcagtca gtggcagtcg
    13501 ctgccggtac ttccggcaga cggaacgcag gtgtctttcc cgtatgccgg agaatggctg
    13561 accgaagacg aaatcagggc tgttcttgat gcggtgcacg atgcggtacg aagcatctgt
    13621 taccaggtgg cagaagatgc gcggcgtatc cgtgcggcgc tgaccaccac cggtcagacg
    13681 ttgctgaccc gccagacgcg ccgctttcgc ctggtcgtga aggaaagcga tcacccctgc
    13741 tggctcgatg aagatgacga aaacctgccc gtggtgctcg atgccatcgt gaaccgggga
    13801 gcacgttttt cgtcggtgga aatgtacctg gtcagcgatt gtattgagca tatcctgtcc
    13861 tgtgggctgg cctgcgatgt gctgcgtata cccgatgaac cgccccgccg ctggtttgac
    13921 cgtggtgttc tgcgggaggt ggtccgggaa gcccgggccg aaatccgcag catggcggat
    13981 gccctggcaa aaatccggaa atgatgacac tggcggggta aatccccgcc tttttcctgc
    14041 cggtccccgg acagagcaca aaggaagtcg ccgccggctc cgctttaccc ggccatgcgg
    14101 ggcatggcct tgtgggtttt cagttatgtg gccaccgtgt cgtgtgcggg ctgtgccgtg
    14161 cctccatctt agccgggctg gcagggatgc aagggtacgc ttcgccgctg cggtcacccg
    14221 gtccctcctt cccgtctgcc gtgattttcc ggtcgttcac ccgctcaggt ttcgcggtct
    14281 caccctccaa ctcccgccag ccgtgtgcgt caggctgcgg cttcccttgc gccctgtgca
    14341 tccccgcctt atcgcccggc ttttatggag gcacggcacc gcccggtgtc gcggaatatg
    14401 tgaacaacgg aggaatacat catgcaatat gcgaaacctg tcactctgaa tgttgaagag
    14461 tgcgaccgtc tgttttttct gccttacctg tttggccagg attttctgta tgtcgaagcg
    14521 tctgtgtacg cgctggcgaa aaaaatgatg ccggaatatg aaggcggctt ctggcacttc
    14581 atccgcctgc cggacggtgg cggttacatg atgccggatg gcgaccgttt tcatctggtt
    14641 aacggtgaaa actggtttga ccgcacggtc agtgccgatg ccgcaggcgt cattctgact
    14701 tcccttgtga ttaaccgcca gttgtggctg taccacgaca gcggtaacgc agggttgact
    14761 cacctgtaca ggatgcgcga tgcacagttg tggagccaca tcgaatttca ccccgaatgt
    14821 aacgcgattt acgcggcact ggactgatta acggacgggg cggcaatgcc gcccctgtaa
    14881 aggagacgag aacatgtact gtactgttaa agaaattatc cgcgaagtgc tggatacaga
    14941 cgtgccggac agtgaatgcg tttttgccgt ggtgctgacg cgtggggatg tgcgtcacat
    15001 agcccaggac tggaacctgt cagacgatga gctggaaacc gtcatgcagc gactggacga
    15061 tgcttttgaa catggtgcgg atgtcagcat tgttcatgac gttgttcgtg aactgatggc
    15121 ggaaaagcgc gccagccgtc aggtgacagt tccggcggtg atgctggaaa aagtgatggc
    15181 gctggcaggc agtgaaatga agcgcctgta tgccgtcggg agtgagaacg ggggcgacgg
    15241 tgacgcattc gtcagggagg aacgcgaagc aatggacgtt gtgttacagg cgctggacgg
    15301 ggagcacatg tcatgaatat cagcacagaa acccgcgaaa ttctgcgcaa ttacaaagcc
    15361 gtgattaatg cgcgacgtcg tgaaatgggg cagaaaccgc tcaccaccgc gcagattgtt
    15421 gatgaaatct gcgattttgt ggcgaatcag caggcggttt tcctgggcgg tcactacatc
    15481 ttacagggca gcagaaacag gtgatacagg gcaggcggtg gaggccgtct gtcagcccgc
    15541 gcgaaaaccc ctggcaggct gacgcctgcc ggaagggaag cgggccacgc tgacgcgtcg
    15601 cccgttaccc ttcctgtttg tgatgtgtcc ggaatgtttt tttctgatgt tatttttctg
    15661 tggttaccgt gcctgttact gttcttcttc tttttcctct tcctcttctt cctcttcttt
    15721 ccgttcctct cctgcttatg gcttttccgg gcgtccccct ggtggggcgg gctgtcgtga
    15781 acggagccag cgaagctgtc tccgccctgg cgggcttcca tccctgacgc gaaaccctgg
    15841 cttgcagcga ccgttccggt cgcgccgcct ctgtcgcgcc gtggcctgcg ctcccggcat
    15901 cccggcaaaa ggccgccggg atgtaagggg caacgccgtt tcgcaaaccg cgcttcacgt
    15961 cgttgcggcg ggtccctgct cattgcctgc cgggtgccac acacccgtat gagtccctgt
    16021 cgccggggct gatacagcca caacctgccg cactgactgt ccagggtaaa tgaacagccc
    16081 acaaaatttt ttacccaaaa cccggtaaaa aattttgcgt tctgcccagg acaggtgcgt
    16141 caggccgtgg cagtgatgcc ccttgcggcg aaggttctca aacgggtgaa gttcatacca
    16201 cagggaatac agcagcaggt tcccgcgaaa cgtcaaaacc gcggctcccg aaactcaacg
    16261 ggtgatgttc tttaaaaatc aggatttatt tcaggctccg gcaatacgca tttatttgtt
    16321 ctgtcagtca tccggctggc aggtaatgag aacgcaggaa cagaaggagg aaaacaccgg
    16381 agaacgtcag acgcagatat gaaaaaagca ggtcagggac ctgcttaatc cacgccgtag
    16441 aaatcgccgc aatcgatttt cacggcttca ctaacctgtg tcataaggag tttcatttat
    16501 gacagtaagt attgtttcac cttccgcagc ggctgtaaag ccccgccgtc atccccgttt
    16561 cagacgcgaa gacatccccg cgccggaaat tgaccccgtg ctgaaagcct tcgggcgaca
    16621 cattgcccgg agttttcacc gggggcgtgg tgtacacatc cccgccatga aaaacacggc
    16681 cttcgggcag gtgctccgca cactcgaact gaaacgcgct tttaactgat gaggtgagcc
    16741 gccccgcgag gggcggcaac agacggaagg agaacatttt atgacattag cagccatcac
    16801 catgaccgcc ccggaagccg ccagccctgt gcagatgtac cgcgcgacct actcaccgga
    16861 tgacaacaaa ctacgcctgt atgccgcgtc acgcctcgac ccggagacgt ataaaaaagt
    16921 gcatgatgcc ggtttccgct gggcacccaa acaggcgctg tttgtcgcgc cagcctggac
    16981 accgggccgg gaagacgtgc tcctctcact tgccggagag attgaggatg aagacagcac
    17041 gctcgctgaa cgtcaggaag cacgggcgga gcggtttacc ggatacagcg gaaagcgggc
    17101 cagtgaatcc gcacaggcac ttgatgaagt ggaaagactg gccgcgatga tcccgcccgg
    17161 tcagcccatt cttgtggggc atcacagcga acgccgcgcc cgtcgtgatg cgcagcgtat
    17221 tgaaaacggc atgaa
//
