LOCUS       CP056305.1             22687 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CP056305.1 Escherichia coli strain RHBSTW-00839 plasmid
            pRHBSTW-00839_2, complete sequence.
ACCESSION   CP056305
VERSION     CP056305.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 20:48:01
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 71734
            Orig. end    :: 94421
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22687
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12687]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12687
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..22687
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22687
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     CDS             complement(173..598)
                     /locus_tag="ctg1_75"
                     /transl_table=11
                     /translation="MQYAKPVTLNVEECDRLSFLPYLFGNDFLYAEAYVYALAQKMMPE
                     YQGGFWHFIRLLDGGGYMMPDGDRFHLVNGENWFDRTVSADAAGIILTSLVINRQLWLY
                     HDSGNAGLTHLYRMRDAQLWSHIEFHPECNAIYAALD"
     CDS             1000..1971
                     /gene_functions="other (smcogs) SMCOG1242:transposase
                     (Score: 186; E-value: 1.7e-56)"
                     /gene_kind="other"
                     /locus_tag="ctg1_76"
                     /transl_table=11
                     /translation="MSQPNLQCMGIDVAKLSLDIATTDTIEPFTVGNDEDGFAVITDKL
                     KHTKINLILMEATGGLEAAIACKLQSEGYDVVVINPRQARDFARSMGYLAKTDKLDAAM
                     LAQLALVIDRHPDRSRYIRHLPDEARAVLATMVVRRRQLNHMLVAERNRLYPSHPQSRK
                     SIDNIIDALQNELDRINEQMKQHMTAFFQEQARLIGSVKGVGDITVASLIAELPEQGKL
                     NRREISALTGVAPLNRDSGKMRGKRTTFGGRAGVRATLNMAALVATQFNPAIKLFYQRL
                     LAAGKPKKLALVACMRKLITILNTMLRKGEEWNASFQSQVIS"
     CDS             complement(2232..2444)
                     /locus_tag="ctg1_77"
                     /transl_table=11
                     /translation="MSSAKILNAYFEASEEDRKEFLRVLSHFYKDNRRVPLQEGMESFA
                     VNESIRKSQSINFAPMQGGCPLCGK"
     CDS             complement(2457..3032)
                     /locus_tag="ctg1_78"
                     /transl_table=11
                     /translation="MDEEKTRAEVAHIEFISYGTSRIFDRRMRSLDWKRKVVTFLGVFV
                     PLMIGCAVLSFGLEAPFLPLCITIAGVASIMQLGFSLWSLVSGWDRSYSDCMASVKENT
                     AIYNLAGSVRKKIGKLDEAKLEILIDDLTEKFERREQEDLTLCVSDKELRYANRMSCFY
                     FKKKCHICNVVPLTLKPGKCVCDGCGKF"
     CDS             complement(3101..3439)
                     /locus_tag="ctg1_79"
                     /transl_table=11
                     /translation="MAGKIPAFFLPVPGQSTKEVAAGSALPGHAEHGLVGVQLCGRRVV
                     CGLCRASILAGLALMQATVLMGGGYLKKVRDNIMESPISSKKLTRFDTTLTGCFERDIS
                     RVGHRHFK"
     CDS             complement(4251..5222)
                     /locus_tag="ctg1_80"
                     /transl_table=11
                     /translation="MKRAPVIPKHTIKTQPLEDTPSSAPAAPMVDSLIARVGAMARGNA
                     ITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDALDDLIPSFLLTGQQTP
                     AFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSAYER
                     GQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSARSGD
                     ALQRAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLSSRHQF
                     APGATVLYKGDKMVLNLDRSRIPTECIERIEAILKELEKAAL"
     CDS             complement(5222..6388)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 130.3; E-value: 1.5e-39)"
                     /gene_kind="other"
                     /locus_tag="ctg1_81"
                     /transl_table=11
                     /translation="MRLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGEA
                     ADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAEDV
                     FPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDLHIH
                     AEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPTDPHL
                     MLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDML
                     RDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRETDEVGK
                     GQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
     CDS             complement(6688..7191)
                     /locus_tag="ctg1_82"
                     /transl_table=11
                     /translation="MPGNCPHYGRWPQHGFTSLKKLRPQSVTSRIQPGSDVIVCAEMDE
                     QWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWP
                     LYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNI
                     KHYQ"
     CDS             7305..7931
                     /locus_tag="ctg1_83"
                     /transl_table=11
                     /translation="MSGSAFAVTHHAFSSGAGRTSDGNGSHASTLKSPSYTKSVSWQHH
                     PRLDRPELFRLLRDCQQNDILLIEDVDRLSRLSGEDWNKLKKMIRQKDIRVMAVNVPTT
                     WINSGMSEFDSRLFAAINDMLLDMLAAVARRDYEQRRERQKQGIEKARKDGKYKGRKPN
                     QARYDAINRLIESGSSWSQVQKVPGCSRGTISSAIKRKSGLKSSS"
     CDS             complement(8256..9998)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 187.1; E-value:
                     9.3e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_84"
                     /transl_table=11
                     /translation="MERKQKNSLFNYIYSLMDARGKFLFFSMLFITSLSSIIISISPLI
                     LAKITDLLSGSLSNFSYEYLVLLACLYMFCVISNKASVFLFMILQSSLRINMQKKMSLK
                     YLRELYNENITNLSKNNAGYTTQSLNQASNDIYILVRNVSQNILSPVIQLISTIVVVLS
                     TKDWFSAGVFFLYILVFVIFNTRLTGSLASLRKHSMDITLNSYSLLSDTVDNMIAAKKN
                     NALRLISERYEDALTQENNAQKKYWLLSSKVLLLNSLLAVILFGSVFIYNILGVLNGVV
                     SIGHFIMITSYIILLSTPVENIGALLSEIRQSMSSLAGFIQRHAENKATSPSIPFLNME
                     RKLNLSIRELSFSYSDDKKILNSVSLDLFTGKMYSLTGPSGSGKSTLVKIISGYYKNYF
                     GDIYLNDISLRNISDEDLNDAIYYLTQDDYIFMDTLRFNLRLANYDASENEMFKVLKLA
                     NLSVVNNEPVSLDTHLINRGNNYSGGQKQRISLARLFLRKPAIIIIDEATSALDYINES
                     EILSSIRTHFPDALIINISHRINLLECSDCVYVLNEGNIVASGHFRDLMVSNEYISGLA
                     SVTE"
     CDS             complement(10001..11542)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: mcjC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_85"
                     /sec_met_domain="mcjC (E-value: 0.0, bitscore: 1219.4,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.7e-07, bitscore:
                     24.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIFNVKLNDTSIRIIFCKTLSAFRTENTIVMLKGKAVSNGKPVS
                     TEEIARVVEEKGVSEVIENLDGVFCILIYHFNDLLIGKSIQSGPALFYCKKNMDIFVSD
                     KISDIKFLNPDMTFSLNIKMAEHYLSGNRIATQESLITGIYKVNNGEFIKFNNQLKPVL
                     LRDEFSITKKNNSTIDSIIDNIEMMRDNRKIALLFSGGLDSALIFHTLKESGNKFCAYH
                     FFSDESDDSEKYFAKEYCSKYGVDFISVNKNINFNEKLYFNLNPNSPDEIPLIFEQTDE
                     EGEGQPPIDDDLLYLCGHGGDHIFGQNPSELFGIDAYRSHGLMFMHKKIVEFSNLKGKR
                     YKDIIFSNISAFINTSNGCSPAKQEHVSDMKLASAQFFATDYTGKINKLTPFLHKNIIQ
                     HYAGLPVFSLFNQHFDRYPVRYEAFQRFGSDIFWKKTKRSSSQLIFRILSGKKDELVNT
                     IKQSGLIEILGINHIELESILYENTTTRLTTELPYILNLYRLAKFIQLQSIDYKG"
     CDS             complement(11545..12171)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_86"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 4.4e-14,
                     bitscore: 45.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.2e-23, bitscore: 76.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRYCLTSYREDLVILDIINDSFSIVPDAGSLLKERDKLLKEFPQ
                     LSYFFDSEYHIGSVSRNSDTSFLEERWFLPEPDKTLYKCSLFKRFILLLKVFYYSWNIE
                     KKGMAWIFISNKKENRLYSLNEEHLIRKEISNLSIIFHLNIFKSDCLTYSYALKRILNS
                     RNIDAHLVIGVRTQPFYSHSWVEVGGQVINDAPNMRDKLSVIAEI"
     CDS             12511..12687
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: micJ25"
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_87"
                     /sec_met_domain="micJ25 (E-value: 3.8e-27, bitscore: 87.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKHFHFNKLSSGKKNNVPSPAKGVIQIKKSASQLTKGGAGHVPE
                     YFVGIGTPISFYG"
     CDS_motif       12511..12621
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MIKHFHFNKLSSGKKNNVPSPAKGVIQIKKSASQLTK"
                     /locus_tag="ctg1_87_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       12622..12687
                     /prepeptide="core"
                     /locus_tag="ctg1_87_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="5.40"
                     /molecular_weight="2107.3"
                     /monoisotopic_mass="2106.0"
                     /core_sequence="GGAGHVPEYFVGIGTPISFYG"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MIKHFHFNKLSSGKKNNVPSPAKGVIQIKKSASQLTK"
                     /leader_location="[12510:12621](+)"
     CDS             12635..12730
                     /locus_tag="ctg1_88"
                     /transl_table=11
                     /translation="MCLSILWGLVHLYLSMADILKEELCHFVYQQ"
     CDS             complement(13320..14024)
                     /locus_tag="ctg1_89"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
     CDS             complement(14271..14744)
                     /locus_tag="ctg1_90"
                     /transl_table=11
                     /translation="MKVSLMAAKAKNGVIGCGPDIPWSAKGEQLLFKALTYNQWLLVGR
                     KTFESMGALPNRKYAVVTRSGWTSNDDNVVVFQSIEEAMDRLAEFTGHVIVSGGGEIYR
                     ETLPMASTLHLSTIDIEPEGDVFFPSIPNTFEVVFEQHFTSNINYCYQIWKKG"
     CDS             14900..15913
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 203.7; E-value: 8.6e-62)"
                     /gene_kind="other"
                     /locus_tag="ctg1_91"
                     /transl_table=11
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAFI
                     RFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQEI
                     GRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDFDHG
                     TIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALERKYPR
                     AGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATPHTLRH
                     SFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLTSER"
     CDS             16399..17103
                     /locus_tag="ctg1_92"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
     CDS             complement(17593..17949)
                     /locus_tag="ctg1_93"
                     /transl_table=11
                     /translation="MAELCVDQIGQRRPVGFVADVPGLQPSQLGVGRAGARLRHLGQAQ
                     VDRVGEDRGQQQVLVFGRVARFQMREMPSEARPFVHLQQQFGDLDVRQDHCRLVDQRLG
                     GVGYRRVERRDLQA"
     CDS             complement(17983..18831)
                     /locus_tag="ctg1_94"
                     /transl_table=11
                     /translation="MLPTERRQVLQQRVINGMAVATQRVRSPFQIDRVPQHDGSRYQIE
                     AASPVALLLETAVADFTQAVEKHCPGQRIARLALVQAGMHAAAQFHALQPVQDEQRALD
                     AAQLAERHGQAVLAWVAAELSEHQGGRHRALLDRGGQPQDFVPMGADVLDVERAADHGF
                     QRVIGGVALRDVELGVAQVADARREAEAQEVHQGEDVIGEARRVGVMLLDPQVGLVVQQ
                     AVEHVGRIAHADVHDLGVKWRVLVRNVGVERPPWAAPVFRVDVAGALGLAAGAEVLAVR
                     R"
     CDS             19000..20004
                     /gene_functions="other (smcogs) SMCOG1242:transposase
                     (Score: 360.1; E-value: 1.7e-109)"
                     /gene_kind="other"
                     /locus_tag="ctg1_95"
                     /transl_table=11
                     /translation="MENIALIGIDLGKNSFHIHCQDHRGKAVYRKKFTRPKLIEFLATC
                     PATTIAMEACGGSHFMARKLEELGHFPKLISPQFVRPFVKSNKNDFVDAEAICEAASRP
                     SMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISRLST
                     LLEDSSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEVGQRLLSIPCVGTLT
                     ASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLLVQCAR
                     VFIQKLEHQSGKLADWVRELLCRKSNFVVTCALANKLARIAWALTARQQTYEA"
     CDS             complement(20186..20362)
                     /locus_tag="ctg1_96"
                     /transl_table=11
                     /translation="MLTDTKLRNLKPRDKLYKVNDREGLYVGVASENGIYGHSRFCNTD
                     FDDKLACLNLSGV"
     CDS             20692..21507
                     /locus_tag="ctg1_97"
                     /transl_table=11
                     /translation="MNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGADVI
                     DLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAYLN
                     DIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAALTG
                     AGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRALTGR
                     GPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR"
     CDS             21568..22371
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="resistance (resist) APH3'' (Score: 541.1;
                     E-value: 2.8e-165)"
                     /gene_kind="other"
                     /locus_tag="ctg1_98"
                     /sec_met_domain="APH (E-value: 1e-31, bitscore: 103.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASRR
                     GELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAWPS
                     MGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLLARV
                     ERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLALMIA
                     NAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
ORIGIN
        1 tctgacaggt tccagtcctg agccatatgg cgcacattcc cacgggtcag caccacggca
       61 aaaacgcatt cactgtccgg cacgtctgta tccagtacat cgcggataat ttctttaaca
      121 gtacatgttc tcgtctcctt tacaggggcg gcattgccgc cccgtccgtt aatcagtcca
      181 gcgccgcgta aatcgcgtta cattcggggt gaaattcgat gtggctccac aactgcgcat
      241 cacgcatccg gtacaggtgt gtcagccctg cgttaccgct gtcgtggtac agccacaact
      301 ggcggttaat cacaagggaa gtcagaatga tgcctgcggc atcggcactg accgtgcggt
      361 caaaccagtt ttcaccgtta accagatgaa aacggtcgcc atccggcatc atgtaaccgc
      421 caccgtccag caggcggatg aagtgccaga agcctccctg atattccggc atcatttttt
      481 gcgccagcgc gtacacatat gcttcggcat acagaaaatc gttgccaaat aggtaaggca
      541 gaaaagacag acggtcgcac tcttcaacat tcagagtgac aggtttcgca tactgcatgg
      601 gatttcctcc gttgttcaca tattccgcga caccgggctg tgccgtgcct ccataaaagc
      661 cgggcgataa ggcggggatg catagggcgc aagggaagcc gcagcctgac acacacggct
      721 ggcgggagtt ggagggggag accgcgaaat ctgagcgggt aaacgaccgg aaaatcacgg
      781 cagacgggaa ggagggaccg ggtgaccgca gcggcgaagc gtatccttat atcttgaaga
      841 tggcataaac tgaatctgta ggtctggcaa agctcatgca gcacgtgcga acccgagggt
      901 attaagcccg catgcaagcg tcccgcgcat gagctgagtc actcatcaca aatccgtaca
      961 gttgattgaa accaaattcg tatcgtaagg aagggtcata tgagtcaacc aaatctgcaa
     1021 tgcatgggta ttgatgttgc caaactatcg ctggacatcg ccaccaccga cacgattgag
     1081 ccattcactg tgggtaacga tgaggatggt ttcgctgtta tcacagataa actgaagcac
     1141 accaaaatta acctgattct catggaagct accggtggcc ttgaagcagc cattgcctgt
     1201 aagcttcagt cagaaggata cgatgtggtt gtgatcaacc cacgacaggc tagggatttt
     1261 gcccgttcaa tgggatatct ggctaaaaca gataaacttg acgccgccat gctagcacaa
     1321 ctggccctgg tcattgatcg ccatccggac cgcagtcgtt atatacggca tctgccagat
     1381 gaggcacgag cagtacttgc cacaatggtc gtccgtcgtc gtcagttgaa ccatatgctg
     1441 gtcgctgagc gtaatcgtct ctatccttct catccccaaa gcaggaagag tatcgataac
     1501 attattgatg cgcttcaaaa cgagctcgac cggatcaatg agcaaatgaa acaacacatg
     1561 acagcattct tccaggagca ggccagactg ataggcagcg tgaaaggcgt cggcgatatc
     1621 accgtcgcgt cgctgattgc cgaactaccg gaacagggga aactcaatcg acgggagatt
     1681 agtgctctaa ctggcgtcgc tcctctaaac agagactccg ggaaaatgcg agggaaacgg
     1741 accacgtttg gtggcagagc cggagtgaga gcaacgttga acatggcagc tctggtggct
     1801 acgcagttta atcctgccat aaagctgttc taccagcgtt tgcttgccgc cggaaaaccc
     1861 aaaaaacttg ctctggtcgc ctgcatgcgc aaactcatca ccattctgaa taccatgctc
     1921 agaaaagggg aagagtggaa cgcctcattt caatcacagg taatctcatg actgccggtc
     1981 attttacata atgacagaaa gaacaactta tcccgcaggc ctgttgtgat ccgccctccc
     2041 acggacaaag catccgcgat gtcagtgggg ccgctgctca tagctgctga tagtgcagct
     2101 ttcggctgtt tttgtaccaa atacggagaa ttgcaagata gcgggcaata gccacttttt
     2161 taacaggatg taaagatgct agttacaata taaagaaatc tatcaagccg ctagtcaagc
     2221 ggctttggtc gttacttgcc gcagagtgga cacccacctt gcataggggc aaagttaatt
     2281 gactgcgatt tacggatgct ttcattgacg gcaaagctct ccatgccctc ttgcagaggt
     2341 actcttcggt tatccttata aaaatgacta agaacccgta ggaactcctt tcgatcttct
     2401 tcagaagcct cgaagtaagc gttaagaatt tttgcactac tcatatgttc tccttgttaa
     2461 aatttcccac aaccatcaca aacacatttt cccggtttca aagttagggg aacgacatta
     2521 caaatatggc attttttttt gaagtagaaa caggacatac ggtttgcata acgaagttct
     2581 ttatcactca cacacaaagt taagtcttcc tgctcccttc gctcaaattt ttccgtcaaa
     2641 tcgtctatca aaatttccaa tttggcttcg tcaagcttac ctattttctt gcgaacacta
     2701 ccagctaggt tataaatggc tgtattttcc ttaacggaag ccatgcaatc actatatgag
     2761 cgatcccatc cggaaaccaa agaccacagc gagaacccca attgcatgat acttgccaca
     2821 ccggcaattg tgatgcaaag cggcagaaat ggagcttcaa gtccgaatga taaaactgca
     2881 caacctatca tcagtggaac aaagacccca aggaaggtga caaccttacg cttccagtct
     2941 aaggatctca tacgcctatc aaaaattcga gacgtaccat atgaaataaa ttctatgtgt
     3001 gccacttcag cacgagtttt ctcttcatcc ataatcaata aaacttgtta tccggtgttt
     3061 taatctttaa taagactgac cctgctcata ttatttagaa tcatttaaaa tgtcgatgcc
     3121 cgacacgaga gatatctcgc tcaaaacagc ctgtcagcgt agtatcgaag cgagtcagtt
     3181 ttttgcttga gatgggcgat tccataatat tatcccgtac ttttttcaga taaccgcctc
     3241 ccattaagac agttgcttgc atcaacgcca gcccggctaa gatggaggca cggcacagcc
     3301 cgcacacgac tcgacgtcca cataactgaa cccccacaag gccatgctcc gcatggccgg
     3361 gtaaagcgga gccggcggcg acttcctttg tgctctgtcc ggggaccggc aggaaaaagg
     3421 cggggatttt ccccgccatc gtcatcattt ccggattttt gccagggcat ccgccatgct
     3481 gcggatttca tcccgtgcct ccaagaaaac tcccgcagaa tatagcggtc aaacaagcgg
     3541 cggggcggtt cacccggtat acgcagcaca tcacagacca agccactggc caagatatgt
     3601 tccacacact cactggcagg cattaatgga atcgtagtct cacgctgata atcagatcga
     3661 caatacaagt gagaccgtgg tcccagactg attagcagac caacaatacg agtgggaccg
     3721 cggtcccaga ctgattatca gactaacaat atgagtggga ccgtggtccc agaccgataa
     3781 tcagaccaac aatatgagtg ggaccgtggt cccagactga ttagcagacc gacaatatga
     3841 gtgggaccgt ggtcccagac tgattagcag accgacaata tgagtgggac cgtggtccca
     3901 gactgattag cagaccgaca atatgagtgg gaccgtggtc ccagactgat tagcagacca
     3961 acaatacgag tgggaccgcg gtcccagact gattagcaga ctaacaatat gagtgggccc
     4021 gtggtcccag accgataatc agaccgacaa tatgagtggg accgtggtcc cagactgatt
     4081 atcagaccga caatatgagt gggaccgtgg tcccagactg attatcagac cgacaataca
     4141 actgggaccg tggtcccaga tataatattc aggccagtta gttatgcttt ctagcctgtg
     4201 ctaaaggaaa ttaagtaaag acagataaat gtagactaaa acgtgccgca tcaaagtgcc
     4261 gctttttcaa gttccttaag aatggcttca attctctcta tacactcagt tggaatacga
     4321 gatctatcta ggtttaacac cattttatcg cccttgtaca acactgtcgc tccaggagca
     4381 aactgatgtc gtgagcttaa gctagttctt gaggcagatg acgttttaag cacagacgtt
     4441 aaaagagtga tgacttcttc agcttcaaat atcactcctg cttttttctg ctcgtgaagg
     4501 ttagatgcct gctgcttaag taattcttct ttatctgtaa aagctctttg aagtgcatca
     4561 cctgaccggg cagatagttc accgggatga gaaaaaagag caacaactga tttaggcagt
     4621 ttagctgtgt tgatacagcg ggtaataatc ttacgtgaaa tattttctgc atcagccagc
     4681 gcagaaatat ttccagcaaa ttcattctgc aatcggcttg cataacgctg accacgttca
     4741 taagcacttg ttggcctata atcgttaccc aatctggaca atgcagccat ctgctcatca
     4801 tccagctcac caaccagaac tcgataatca ctttctgtaa gtgcagcagc tttacgacgg
     4861 cggctcccat cggcaatttc tatgacccca gacactcttc gaccgaatgc tggtgtctgc
     4921 tgacctgtca gtagaaaaga agggataaga tcatccaggg cgtcttcggt aagcagttcc
     4981 tggtcacgtt cattacctga ccatacccga gaggtcttct caacactatc tccccggagc
     5041 acctcaaggg taaatttcac gtccctacca catacaggca aagtaatagc attgccacga
     5101 gccatagctc ctacgcgcgc aattaacgaa tccaccatcg gtgcagctgg tgccgatgac
     5161 ggagtatctt caagcggttg agtcttaatc gtatgttttg gaatgacagg cgcacgcttc
     5221 attatctaat ctcccagcgt ggtttaatca aacgatcgaa aatttcattg cagacaggtt
     5281 cccaaataga aagggcattt ctccaggcac ctgttgaaga gcgttgatca atagcctgtt
     5341 caaaaacagt tctcatccgg atctgacctt taccaacttc atccgtttca cgcacaacat
     5401 tttttaggac catgcttccc caggcgtccc gaatttgctc ctccatccac ggggactgag
     5461 aaccattact attactgtat ttagtaagca aaatacgtac atcaggctcg aatcctttaa
     5521 gatctacgtt tttgagcaga tcacgaagca tatcgaaaaa ctgcagagcg gaagtgtagt
     5581 cgaacaactc agcaggcgtg gggacaatca acacatcagc agcacataca acattaatcg
     5641 tgccgatacc taggttaggc gcgctgtcaa tgacaatgac atcatagtca tgagcgacgg
     5701 tttcaatggc cagtcggagc atcaggtgtg gatcggtggg caatttacct tcatcaaatt
     5761 tgcccattag ctcagtttca atgcggtgca gagccaaaca ggaaggaata atgtcaagcc
     5821 caggccagca agtaggcttt attgcataag tgacatcgtc cttttcccca agatagaagg
     5881 gaaggagagt atcctctgca tgaatatgaa gatctggcac ccagccgtga tacatcgatg
     5941 ctgttccctg ggggtcgtta ccttccacga gcagaacacg taatcccttc agagccagat
     6001 cctgagcaag atgaacagaa acagaggttt tgtaaacgcc ccctttatga gcagcaactc
     6061 caatcaccgg cggaaatacg tcttcagcac gtcgtagtct cgtaccaaac acgtcacgca
     6121 tatgattaat ttgttcaatt gtataaccaa cacgttgctc aacccgtcct cgtatttcca
     6181 tatccgggtg cggtagccgg cctgctttct cggcatccct gatagcctga gaagatactc
     6241 caactaaatc cgctgcttca cctattctcc agcgtcgggt gattttcctc gcttccgggc
     6301 tgtcatcatt aaactgtgca atggcgatag ccttcgtcat ttcatgacca gcgtttatgc
     6361 actggttaag tgtttccatg agtctcattc tgaacatcct ttaatcattg ctttgcatat
     6421 tttcatttaa tcttgcattt tattgcaaag caacaacaaa attgcaaagt agtcaaaaaa
     6481 ccgcaaagtt gtttaaaatg agagcaacac atcaaaaaag gaaacaggaa gagcacatac
     6541 ctcagtcaat aattatcact agtactcgta gccgtcgtgt aaccgagcgt agcgagctaa
     6601 ctggcgagga cgcgcgctaa ctgttcacac tcagtatccc tagcaccaaa ataactatct
     6661 gatggtcaag gcggtaatga ctccaactta ttgatagtgt tttatgttca gataatgccc
     6721 gatgactttg tcatgcagct ccaccgattt tgaaaacgac agcgacttcc gtcccagccg
     6781 tgccaggtgc tgcctcagat tcaggttatg ccgctcaatt cgctgcgtat atcgcttgct
     6841 gattacgtgc agctttccct tcaggcggga ttcatacagc ggccagccat ccgtcatcca
     6901 tatcaccacg tcaaagggtg acagcaggct cataagacgc cccagcgtcg ccatagtgcg
     6961 ttcaccgaat acgtgcgcaa caaccgtctt ccggagactg tcatacgcgt aaaacagcca
     7021 gcgctggcgc gatttagccc cgacatagcc ccactgttcg tccatttccg cgcagacaat
     7081 cacatcactg cccggttgta tgcgcgaggt taccgactgc ggcctgagtt ttttaagtga
     7141 cgtaaaaccg tgttgaggcc aacgcccata atgcgggcag ttgcccggca tccaacgcca
     7201 ttcatggcca tatcaatgat tttctggtgc gtaccgggtt gagaagcggt gtaagtgaac
     7261 tgcagttgcc atgttttacg gcaatgagag cagagatagc gctgatgtcc ggcagtgctt
     7321 ttgccgttac gcaccacgcc ttcagtagcg gagcaggaag gacatctgat ggaaatggaa
     7381 gccacgcaag caccttaaaa tcaccatcat acactaaatc agtaagttgg cagcatcacc
     7441 ctcgtctcga tcgtcctgaa ctcttccgtc ttctgagaga ttgccagcaa aatgacattt
     7501 tgctcattga ggacgttgac agactttccc gcctgtcagg ggaagactgg aataagctga
     7561 agaaaatgat ccgtcagaaa gatatccggg ttatggccgt gaacgttccg accacatgga
     7621 ttaattctgg catgagtgag tttgacagcc ggttgtttgc tgccattaac gatatgctgc
     7681 tggatatgct ggccgctgtt gccagaaggg actatgaaca acgacgggaa cgccagaaac
     7741 aagggataga gaaagcaagg aaagacggca aatataaagg tcgtaaacct aatcaagcca
     7801 gatatgacgc aattaacagg ttgattgaga gcggaagctc ctggagtcaa gttcagaaag
     7861 tgccagggtg cagccgtggc acaatcagta gcgcaataaa acgtaaatcc gggctgaaat
     7921 ccagtagtta gagaagggag gagatgtcgg aagttcggaa aacaaccccc gttaagatta
     7981 ttttttaatc aaattgtttt tggggcacct gaactgcggg gttacagcgg tttttgtgtc
     8041 tgaaaccgta caattctgta catttacgca aggggatgtg cggaagaagt aagctaaacg
     8101 attagcggac ggtcagagca tttcgaacaa cccttacatt ctggggctta gcttgccggg
     8161 atgtaaccac tcgtgcaacc caattctctt aacgtgggaa aaattccgtt ttccaagcga
     8221 ctccctttct gaatacagag caggagtcag atattttatt cagtaacaga agccagtccc
     8281 gatatgtatt cattgctgac catcaaatcc ctgaaatggc cagaagcaac aatatttcct
     8341 tcattcaata cataaacaca atcggaacac tccagaagat ttattcggtg actaatattt
     8401 ataattaacg catcaggaaa atgagttctt attgatgata aaatttctga ttcattaata
     8461 taatccagag ccgatgtggc ttcatcaata ataattattg caggttttct caaaaacagt
     8521 cgcgctaacg aaattcgttg tttttgccct cctgaatagt tattgcctct gtttataagg
     8581 tgtgtatcca gactcactgg ttcattgttg acgacagaaa gatttgccag tttaagaact
     8641 ttaaacattt cattttctga cgcgtcgtaa tttgcgagcc ggagattaaa tcgtagtgta
     8701 tccataaaaa tataatcatc ttgtgttagg tagtaaatag catcattcaa atcctcatca
     8761 ctgatattac gtaaggatat atcattcaga taaatgtctc caaagtaatt tttatagtaa
     8821 cctgatatta tttttacaag ggtggatttt cctgaaccac tgggtccggt taatgaatac
     8881 atttttccgg taaaaaggtc aagactgact gaattaagta tttttttatc atcactatag
     8941 ctaaatgaaa gctctcttat ggacaggttt aattttcgct ccatgttgag aaaaggtatt
     9001 gaaggagatg tggctttatt ctcggcatga cgttgaataa aacctgccag gctagacatt
     9061 gactgcctga tctcacttag caatgcccct atattttcca ctggcgttga aagaagaatg
     9121 atatatgatg taatcataat gaagtggccg atactaacta caccattcag cacacctaaa
     9181 atattatata tgaatacaga accaaataat attacagcaa gtaaagagtt caataaaaga
     9241 actttagaac tgagtaacca gtattttttc tgagcattgt tttcctgagt gagagcatct
     9301 tcataacgtt cagaaataag tcttaatgca ttattctttt tagctgctat catgttatca
     9361 acagtatcag ataacagact ataagagtta agagtgatat ccatgctgtg ttttctgagt
     9421 gacgctaaac tgccagtcag tctggtatta aaaattacaa ataccagaat atagagaaaa
     9481 aacacaccgg cagaaaacca gtccttcgta gataaaacaa caacaatagt agaaataagt
     9541 tgtataacag gtgacaggat attctgggaa acatttctca caagaatata aatgtcattt
     9601 gaagcctggt taagactttg cgttgtatat ccagcattat ttttactcaa gttagttata
     9661 ttttcgttat acaattctct caaatatttt agcgacattt ttttctgcat gttaatacgt
     9721 agactacttt gcagtatcat aaataaaaaa acacttgctt tattagatat aacgcaaaac
     9781 atgtataaac aggcaagtaa aaccagatat tcataactaa aatttgacaa tgagccagac
     9841 agtaaatctg taatctttgc aagaatcaat ggtgaaatag atatgattat cgatgataat
     9901 gatgtaatga ataacatgga aaagaataaa aatttacctc ttgcatccat taatgaataa
     9961 atataattaa ataatgagtt tttctgtttt ctttccataa ttaaccttta taatcaatgg
    10021 attgaagttg aatgaatttt gccagacggt ataagttaag tatatatggt agttccgttg
    10081 tcagacgtgt agtcgtattt tcatacaaaa tgctttctaa ttcaatatgg ttaatgccta
    10141 atatttcaat taatcctgac tgttttattg tattcactag ttcatccttt ttaccggata
    10201 gaattctgaa tattagctgt gaagatgacc gtttggtttt tttccagaaa atatctgaac
    10261 caaatcgttg aaacgcttca taacgaacgg gataacgatc aaagtgctgg ttaaatagac
    10321 taaaaactgg taagccagca taatgctgga taatattttt atgcaggaat ggagttagtt
    10381 tattaatttt tcctgtataa tcagttgcaa aaaactgagc agaggcaagt ttcatatctg
    10441 atacgtgctc ttgctttgct ggagaacatc cgttggatgt attaatgaat gcggaaatat
    10501 ttgaaaatat gatatcttta tatctctttc ccttgagatt ggaaaattct actatttttt
    10561 tatgcataaa catcaagcca tgacttcgat atgcatcaat gccaaaaagt tctgaaggat
    10621 tttgtccgaa aatatgatct ccaccgtgac cacatagata taataaatca tcgtctatgg
    10681 ggggctgacc ttcaccttct tcatctgtct gttcaaatat caaagggatt tcgtccggac
    10741 tattaggatt taaattgaaa taaagttttt cattaaagtt gatgttttta ttaacagata
    10801 taaaatcaac tccatatttt gaacagtatt ccttagcaaa atacttttca ctgtcatcag
    10861 attcatcaga aaaaaaatga taagcgcaga atttgttacc tgattcttta agtgtgtgaa
    10921 aaattaatgc agaatccaat cctccggaga ataatagggc tatttttcta ttatcccgca
    10981 tcatctcaat attatcaatg atactgtcga tagttgaatt gttctttttg gtaatactaa
    11041 actcatcacg aagtagcaca ggtttcaact gattattaaa ttttataaac tcaccattat
    11101 ttactttgta aatgccagtg attagtgatt cctgggttgc tattcgattt cctgacagat
    11161 aatgttctgc catttttata tttagactga atgtcatatc tggattcaaa aatttgatat
    11221 cagaaatttt atccgaaaca aaaatatcca tattcttttt acaataaaat agagcggggc
    11281 ctgattgaat gcttttccct ataaggagat cattaaaatg ataaattagg atacagaaaa
    11341 caccatctaa attttctatt acttctgaaa cacctttttc ttccactact ctggcaatct
    11401 cctctgtgga tacaggtttg ccatttgaaa ctgcttttcc tttgagcata acgatggtat
    11461 tttctgtccg gaaggcagaa agcgttttac agaaaataat tctaattgaa gtatcattta
    11521 acttgacatt aaatatttcc ataactatat ctctgcaata acagataatt tatcccgcat
    11581 attgggagca tcattgataa cttgtccccc aacctccacc caagagtggc tataaaaagg
    11641 ttgtgtcctt acaccaataa caagatgagc atcaatattt ctggaattaa gaattctttt
    11701 tagtgcgtat gaataggtaa gacagtcaga tttaaaaata ttaagatgaa agataatgga
    11761 aagattacta atttctttcc ggataagatg ctcttcattc aaggagtata gcctattctc
    11821 ttttttatta cttatgaaaa tccatgccat cccttttttt tcaatattcc agctatagta
    11881 aaagactttg agtaataata taaatcgttt aaatagagaa cacttatata atgttttgtc
    11941 aggttctggt agaaaccagc gttcttcaag aaaagaagtg tcactattac gagaaacact
    12001 tccaatatga tattcactgt caaaaaagta agatagttgt gggaattctt taagcaattt
    12061 atctctttct tttagcaagc tacctgcgtc aggcactatg ctgaaactat cattaattat
    12121 atccaggata acaagatcct ctctataact ggttaagcag taacggatca ttttgcacac
    12181 tccctcctgt agttatgcct ttacactcaa ttggaataat aaaacttctg aatttatcta
    12241 caagctaaat ttttttctta attgatggct aaatattctg aaataattag aaaaatgtat
    12301 aaaaatccaa aatattgtac taaatttgac cacttttgca gattgattag tttatggatg
    12361 tttgtatcta aataatttta ttgataaatt actaaagcgt aatgattatt gatctcaatt
    12421 ttattttgtg ctaataaaat tctaacagaa ggacgtgagg ttcctctgta aaaatcatca
    12481 tactattttc atcaaataag gaacgtaaaa atgattaagc attttcattt taataaactg
    12541 tcttctggta aaaaaaataa tgttccatct cctgcaaagg gggttataca aataaaaaaa
    12601 tcagcatcgc aactcacaaa aggtggtgca ggacatgtgc ctgagtattt tgtggggatt
    12661 ggtacaccta tatctttcta tggctgatat tctgaaagaa gaactctgtc attttgtcta
    12721 tcaacaataa atcacatatc agaagctttt tgaaaattaa ctcaagaaat actatggagg
    12781 atcatggagg gggcaggaat actttacatg gcgttattac agagttaaca actgcccctt
    12841 tgaaaattac atatgctggc tgggagctat ttggaacttc ctgtcctgag ttacgtttcc
    12901 gctgtcatca aacgatgaac tggcgaatca gttccagaac tgcaatccgc gcgtttgcaa
    12961 cggcgaccac atccctgaga atgatgatta acaggttaat cattcgtttc tcttagccca
    13021 acctcactga actgaccccc ataaagttgg gcttttctgt gcctgttgtt caccagtttc
    13081 ccagacacgt cgcctggtga cgtgagaacc tggttcaaat ttactgttct ggccatatgc
    13141 attcaggaaa ctggctatca gctccgatgc tgtcgccgat attgtcattc actgatattt
    13201 ttcagtaggt tacaggaaat gacacattca aaaaatagtc atttgttgat ggatacagta
    13261 tcgacggggc actgttgcaa agttagcgat gaggcagcct tttgtcttat tcaaaggcct
    13321 tacatttcaa aaactctgct taccaggcgc atttcgccca ggggatcacc ataataaaat
    13381 gctgaggcct ggcctttgcg tagtgcacgc atcacctcaa tacctttgat ggtggcgtaa
    13441 gccgtcttca tggatttaaa tcccagcgtg gcgccgatta tccgtttcag tttgccatga
    13501 tcgcattcaa tcacgttgtt ccggtactta atctgtcggt gttcaacgtc agacgggcac
    13561 cggccttcgc gtttgagcag agcaagcgcg cgaccatagg cgggcgcttt atccgtgttg
    13621 atgaatcgcg ggatctgcca cttcttcacg ttgttgagga ttttacccag aaaccggtat
    13681 gcagctttgc tgttacgacg ggaggagaga taaaaatcga cagtgcggcc ccggctgtcg
    13741 acggcccggt acagatacgc ccagcggcca ttgaccttca cgtaggtttc atccatgtgc
    13801 cacgggcaaa gatcggaagg gttacgccag taccagcgca gccgtttttc catttcaggc
    13861 gcataacgct gaacccagcg gtaaatcgtg gagtgatcga cattcactcc gcgttcagcc
    13921 agcatctcct gcagctcacg gtaactgatg ccgtatttgc agtaccagcg tacggcccac
    13981 agaatgatgt cacgctgaaa atgccggcct ttgaatgggt tcatgtgcag ctccatcagc
    14041 aaaaggggat gataagttta tcaccaccga ctatttgcaa cagtgccgtc ctgcgaatat
    14101 gtgagttttg acctaatgag ccacaaaaac tcattttcgc ccacgataat ttttctactt
    14161 cctttctttg gaatgctcat ttcaatattc acataacgtc gctatcaatc gcggaaaagg
    14221 cgtagtgcgc gaagcgaacg aagctttttg ccgtcgattg catagctttg ttaacccttt
    14281 ttccaaattt gatagcaata gttaatgttt gaagtaaagt gttgctcaaa aacaacttcg
    14341 aaggtatttg gaatactcgg gaagaaaaca tccccctctg gctcgatgtc gatcgtcgat
    14401 aagtggagcg tagaggccat gggtaatgtt tctcggtaaa tttctccgcc accagacact
    14461 ataacgtgac cggtgaattc agctagcctg tccatggcct cttcgattga ctgaaataca
    14521 actacattgt catcatttga tgtccaacct gagcgggtaa cgaccgcgta tttcctattg
    14581 gggagtgcgc ccatagattc aaacgtcttg cgacccacca gaagccactg attgtaggtc
    14641 aatgctttaa aaagtagctg ctcccctttc gcggaccagg gtatgtctgg accgcaacca
    14701 atcacgccgt ttttcgcttt cgcagccatc aatgatactt tcaaggttct catcctgggt
    14761 taactttgtt ttagggcgac tgccctgctg cgtaacatcg ttgctgctcc ataacatcaa
    14821 acatcgaccc acggcgtaac gcgcttgctg cttggatgtc cgaggcatag actgtacaaa
    14881 aaaacagtca taacaagcca tgaaaaccgc cactgcgccg ttaccaccgc tgcgttcggt
    14941 caaggttctg gaccagttgc gtgagcgcat acgctacttg cattacagtt tacgaaccga
    15001 acaggcttat gtccactggg ttcgtgcctt catccgtttc cacggtgtgc gtcacccggc
    15061 aaccttgggc agcagcgaag tcgaggcatt tctgtcctgg ctggcgaacg agcgcaaggt
    15121 ttcggtctcc acgcatcgtc aggcattggc ggccttgctg ttcttctacg gcaaggtgct
    15181 gtgcacggat ctgccctggc ttcaggagat cggaagacct cggccgtcgc ggcgcttgcc
    15241 ggtggtgctg accccggatg aagtggttcg catcctcggt tttctggaag gcgagcatcg
    15301 tttgttcgcc cagcttctgt atggaacggg catgcggatc agtgagggtt tgcaactgcg
    15361 ggtcaaggat ctggatttcg atcacggcac gatcatcgtg cgggagggca agggctccaa
    15421 ggatcgggcc ttgatgttac ccgagagctt ggcacccagc ctgcgcgagc agctgtcgcg
    15481 tgcacgggca tggtggctga aggaccaggc cgagggccgc agcggcgttg cgcttcccga
    15541 cgcccttgag cggaagtatc cgcgcgccgg gcattcctgg ccgtggttct gggtttttgc
    15601 gcagcacacg cattcgaccg atccacggag cggtgtcgtg cgtcgccatc acatgtatga
    15661 ccagaccttt cagcgcgcct tcaaacgtgc cgtagaacaa gcaggcatca cgaagcccgc
    15721 cacaccgcac accctccgcc actcgttcgc gacggccttg ctccgcagcg gttacgacat
    15781 tcgaaccgtg caggatctgc tcggccattc cgacgtctct acgacgatga tttacacgca
    15841 tgtgctgaaa gttggcggtg ccggagtgcg ctcaccgctt gatgcgctgc cgcccctcac
    15901 tagtgagagg tagggcagcg caagtcaatc ctggcggatt cactacccct gcgcgaaggc
    15961 catcggtgcc gcatcgaacg gccggttgcg gaaagtcctc cctgcgtccg ctgatggccg
    16021 gcagcagccc gtcgttgcct gatggatcca acccctccgc tgctatagtg cagtcggctt
    16081 ctgacgttca gtgcagccgt cttctgaaaa cgacaaacag ccagaaaggc tgttacaggc
    16141 gatttgatct gcaacctatt ggttaaatta atgtatcaaa aacgatggtt tttgtgacag
    16201 tcttgaaaag tcctgacttc tcccgaaaaa tgactcccct catgtaacaa aactcgttac
    16261 tgtatcaaca taacaataac cccataacta attagcgaga aaagaatgaa aatcggctat
    16321 gcacgtaaat ctacgggcac tgttgcaaat agtcggtggt gataaactta tcatcccctt
    16381 ttgctgatgg agctgcacat gaacccattc aaaggccggc attttcagcg tgacatcatt
    16441 ctgtgggccg tacgctggta ctgcaaatac ggcatcagtt accgtgagct gcaggagatg
    16501 ctggctgaac gcggagtgaa tgtcgatcac tccacgattt accgctgggt tcagcgttat
    16561 gcgcctgaaa tggaaaaacg gctgcgctgg tactggcgta acccttccga tctttgcccg
    16621 tggcacatgg atgaaaccta cgtgaaggtc aatggccgct gggcgtatct gtaccgggcc
    16681 gtcgacagcc ggggccgcac tgtcgatttt tatctctcct cccgtcgtaa cagcaaagct
    16741 gcataccggt ttctgggtaa aatcctcaac aacgtgaaga agtggcagat cccgcgattc
    16801 atcaacacgg ataaagcgcc cgcctatggt cgcgcgcttg ctctgctcaa acgcgaaggc
    16861 cggtgcccgt ctgacgttga acaccgacag attaagtacc ggaacaacgt gattgaatgc
    16921 gatcatggca aactgaaacg gataatcggc gccacgctgg gatttaaatc catgaagacg
    16981 gcttacgcca ccatcaaagg tattgaggtg atgcgtgcac tacgcaaagg ccaggcctca
    17041 gcattttatt atggtgatcc cctgggcgaa atgcgcctgg taagcagagt ttttgaaatg
    17101 taaggccttt gaataagaca aaaggctgcc tcatcgctaa ctttgcaaca gtgccagctg
    17161 cgggccgctc ccgccgcgaa ggacgtgctc gacgccatcg aggtgctgcg cggcatgaac
    17221 agcgacaacg cccgcaaggt gcccgccgac gcgccgaccg agttcatcaa gccgcgctgg
    17281 cagaagctgg tcatgaccga caccggcatc gaccggcgct actacgaact gtgcgcgctg
    17341 tcggagatga agaacgcgtt gcgttccggc gacatctggg tgcaggggtc gcgccagttc
    17401 aaggacttcg aggactacct ggtgccgccc gcgaaattcg ccagcctcaa gcaggccagc
    17461 gaattgccgc tggccgtggc caccgactgc aaccggtacc tgaacgaccg gctgacgctg
    17521 ctggaaacac agcttgccac cgtcaaccgt atggcgacgg ccaacgagct gccggacgcc
    17581 atcatcaccg agtcaggctt gaagatcacg ccgctcgacg cggcggtacc cgacaccgcc
    17641 caagcgctga tcgaccagac ggcaatgatc ctgccgcacg tcaagatcac cgaactgctg
    17701 ctggaggtgg acgaatggac gggcttcact cggcatttcg cgcatctgaa atcgggcgac
    17761 ccggccaaag acaagaacct gttgctgacc acgatcctcg ccgacgcgat caacctgggc
    17821 ctgaccaaga tggcggagtc ttgccccggc acgacctacg ccaagctggc ttggctgcaa
    17881 gcctggcaca tccgcgacga aacctacggg gcggcgctgg ccgatctggt caacgcacag
    17941 ttccgccatc ccttcgccga gcactggggc gacggcacca cctcatcgtc ggacggccag
    18001 aacttccgca ccggcagcaa ggccgagagc accggccaca tcaacccgaa atacgggagc
    18061 agcccagggc ggacgttcta cacccacatt tctgaccagt acgcgccatt tcacaccaag
    18121 gtcgtgaacg tcggcgtgcg cgattcgacc tacgtgctcg acggcctgct gtaccacgag
    18181 tccgacttgc ggatcgagga gcattacacc gacacggcgg gcttcaccga tcacgtcttc
    18241 gccctgatgc acctcctggg cttccgcttc gcgccgcgca tccgcgacct gggcgacacc
    18301 aagctctaca tcccgaaggg cgacgccgcc tatgacgcgc tgaaacccat gatcggcggc
    18361 acgctcaaca tcaagcacgt ccgcgcccat tgggacgaaa tcctgcggct ggccacctcg
    18421 atcaagcagg gcacggtgac ggcctccctg atgctccgaa agctcggcag ctacccacgc
    18481 cagaacggcc tggccgtggc gctccgcgag ctgggccgca tcgagcgcac gctgttcatc
    18541 ctggactggc tgcaaagcgt ggaactgcgc cgccgcgtgc atgccggcct gaacaagggc
    18601 gaggcgcgca atgcgctggc cagggcagtg tttttcaacc gcctgggtga aatccgcgac
    18661 cgcagtttcg agcagcagcg ctaccgggct agcggcctca atctggtaac ggctgccgtc
    18721 gtgttgtgga acacggtcta tctggaacgg gctgcgcacg cgctgcgtgg caacggccat
    18781 gccgttgatg acgcgctgtt gcagtacctg tcgccgctcg gttgggagca catcaacctc
    18841 accggcgatt acctctggcg cagcagcgcc aagatcggcg cgggcaagtt caggccgcta
    18901 cgaccgctgc aaccggctta gcgtgcttta tttaatgaga tggtcactcc ctccttccca
    18961 gtactatgct gaggacaggc tttcattcgg agaaccatca tggaaaacat tgcgcttatt
    19021 ggtatcgatc tgggtaagaa ctctttccat attcattgtc aggatcatcg tgggaaggcc
    19081 gtttaccgta aaaaattcac ccgaccaaag ctaatcgaat ttctggcgac atgcccggca
    19141 acaaccatcg cgatggaagc ctgtggcggt tctcacttta tggcacgcaa gctggaagag
    19201 ttagggcatt ttccaaagct gatatcaccg caatttgtcc gcccattcgt taaaagcaac
    19261 aaaaatgact tcgttgatgc tgaagctatc tgtgaagcag catcacgtcc atctatgcgt
    19321 ttcgtgcagc ccagaaccga atctcagcag gcaatgcgag ctctgcatcg tgtccgtgaa
    19381 tccctggttc aggataaggt gaaaacaact aatcagatgc atgcttttct gctggaattt
    19441 ggtatcagcg ttccgcgagg tgctgccgtt attagtcgac tgagtaccct tcttgaggac
    19501 agtagtttgc ctctttatct cagccagtta ctgctgaaat tacaacagca ttatcactat
    19561 cttgttgagc agattaaaga tctggaatct cagttgaaac gaaagttgga cgaagatgag
    19621 gttggacagc gcttgctgag tattccctgc gttggaacgc tgactgccag tactatttca
    19681 actgagattg gcgacgggaa gcagtacgcc agcagccgtg actttgcggc ggcaacaggg
    19741 ctggtacccc gacagtacag cacgggaggt cggacgacat tgttagggat tagcaagcgg
    19801 ggcaacaaaa agatccgaac tttgttggtt cagtgtgcca gggtattcat acaaaaactg
    19861 gaacaccagt ctggcaagtt ggccgactgg gtcagggagt tgttgtgtcg gaaaagcaac
    19921 tttgtcgtca cctgtgctct ggcaaacaag ctggccagaa tagcctgggc actgacggcg
    19981 cgacagcaaa cttacgaagc ataaaggcag aaatacacca gtttaaacaa tcattcatct
    20041 ggttttgcga atactgatat tgatgatact aacggcccac cggcctgttg aggaacctgt
    20101 aaaacggaaa ggctcattga agccgtatat tttctggagg ttcatcaggc gcggaactca
    20161 tcgaggcgcg ggaataaaat cccattcaga cgccggatag attcaagcaa gccaacttgt
    20221 cgtcaaaatc ggtgttgcaa aaacgggagt gaccatagat tccgttttct gaggcgaccc
    20281 ccacatagag accttcccgg tcattcactt tgtagagttt gtccctgggc ttgagattgc
    20341 gcagcttggt atcggtcagc atgtaccttg tccttcttcg tctccgatac ccactctatt
    20401 gtaaacaaga catttttatc ttttatattc aatggcttat tttcctgcta attggtaata
    20461 ccatgaaaaa taccatgctc agaaaaggct taacaatatt ttgaaaaatt gcctactgag
    20521 cgctgccgca cagctccata ggccgctttc ctggctttgc ttccagatgt atgctattct
    20581 gctcctgcag ctaatggatc accgcaaaca ggttactcgc ctggggattc cctttcgacc
    20641 cgagcatccg tatgagactc atgctcgatt attattatta tagaagcccc catgaataaa
    20701 tcgctcatca ttttcggcat cgtcaacata acctcggaca gtttctccga tggaggccgg
    20761 tatctggcgc cagacgcagc cattgcgcag gcgcgtaagc tgatggccga gggggcagat
    20821 gtgatcgacc tcggtccggc atccagcaat cccgacgccg cgcctgtttc gtccgacaca
    20881 gaaatcgcgc gtatcgcgcc ggtgctggac gcgctcaagg cagatggcat tcccgtctcg
    20941 ctcgacagtt atcaacccgc gacgcaagcc tatgccttgt cgcgtggtgt ggcctatctc
    21001 aatgatattc gcggttttcc agacgctgcg ttctatccgc aattggcgaa atcatctgcc
    21061 aaactcgtcg ttatgcattc ggtgcaagac gggcaggcag atcggcgcga ggcacccgct
    21121 ggcgacatca tggatcacat tgcggcgttc tttgacgcgc gcatcgcggc gctgacgggt
    21181 gccggtatca aacgcaaccg ccttgtcctt gatcccggca tggggttttt tctgggggct
    21241 gctcccgaaa cctcgctctc ggtgctggcg cggttcgatg aattgcggct gcgcttcgat
    21301 ttgccggtgc ttctgtctgt ttcgcgcaaa tcctttctgc gcgcgctcac aggccgtggt
    21361 ccgggggatg tcggggccgc gacactcgct gcagagcttg ccgccgccgc aggtggagct
    21421 gacttcatcc gcacacacga gccgcgcccc ttgcgcgacg ggctggcggt attggcggcg
    21481 ctgaaagaaa ccgcaagaat tcgttaactg cacattcggg atatttctct atattcgcgc
    21541 ttcatcagaa aactgaagga acctccattg aatcgaacta atattttttt tggtgaatcg
    21601 cattctgact ggttgcctgt cagaggcgga gaatctggtg attttgtttt tcgacgtggt
    21661 gacgggcatg ccttcgcgaa aatcgcacct gcttcccgcc gcggtgagct cgctggagag
    21721 cgtgaccgcc tcatttggct caaaggtcga ggtgtggctt gccccgaggt catcaactgg
    21781 caggaggaac aggagggtgc atgcttggtg ataacggcaa ttccgggagt accggcggct
    21841 gatctgtctg gagcggattt gctcaaagcg tggccgtcaa tggggcagca acttggcgct
    21901 gttcacagcc tatcggttga tcaatgtccg tttgagcgca ggctgtcgcg aatgttcgga
    21961 cgcgccgttg atgtggtgtc ccgcaatgcc gtcaatcccg acttcttacc ggacgaggac
    22021 aagagtacgc cgcagctcga tcttttggct cgtgtcgaac gagagctacc ggtgcggctc
    22081 gaccaagagc gcaccgatat ggttgtttgc catggtgatc cctgcatgcc gaacttcatg
    22141 gtggacccta aaactcttca atgcacgggt ctgatcgacc ttgggcggct cggaacagca
    22201 gatcgctatg ccgatttggc actcatgatt gctaacgccg aagagaactg ggcagcgcca
    22261 gatgaagcag agcgcgcctt cgctgtccta ttcaatgtat tggggatcga agcccccgac
    22321 cgcgaacgcc ttgccttcta tctgcgattg gaccctctga cttggggttg atgttcatgc
    22381 cgcctgtttt tcctgctcat tggcacgttt cgcaacctgt tctcattgcg gacacctttt
    22441 ccagcctcgt ttggaaagtt tcattgccag acgggactcc tgcaatcgtc aagggattga
    22501 aacctataga agacattgct gatgaactgc gcggggccga ctatctggta tggcgcaatg
    22561 ggaggggagc agtccggttg ctcggtcgtg agaacaatct gatgttgctc gaatatgccg
    22621 gggagcgaat gctctctcac atcgttgccg agcacggcga ctaccaggcg accgaaattg
    22681 cagcgga
//
