LOCUS       CP050284.1             16223 bp    DNA              UNK 01-JAN-1980
DEFINITION  CP050284.1 Klebsiella pneumoniae strain 9949 plasmid unnamed4,
            complete sequence.
ACCESSION   CP050284
VERSION     CP050284.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 15:53:06
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(159..1646)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
     CDS             2291..2536
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
     CDS             2810..3181
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
     CDS             3178..3543
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
     CDS             3718..3996
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
     CDS             3984..4298
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
     CDS             4462..4890
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
     CDS             4916..5095
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
     CDS             complement(5122..5652)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
     protocluster    5338..16223
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10337:11735]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10338..11735
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    5338..16223
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          5338..16223
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(5659..6390)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
     CDS             complement(6390..7985)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLVAGVLL
                     ARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNALADFS
                     TEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRCVRDFG
                     DAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLVAGFNL
                     SETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLITKLENV
                     ADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARDEFRRW
                     PHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFVKTTVL
                     DNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQKEARPL
                     FDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEYLPPAD
                     GGGPKADDDFAGLY"
     CDS             complement(9068..9196)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MEKRHRRGPAVLPHMLVPCLSTESVGNFVCVRSARRSLTPGA"
     CDS             complement(10071..10328)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
     CDS             complement(10338..11735)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_14"
                     /sec_met_domain="Cloacin (E-value: 1.5e-110, bitscore:
                     358.1, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFGLPALATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLW
                     GIAIYGVLPSEIAKDDPKMMSKIMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKD
                     ERQHIAVVAGRPMSVPVVDAKPTKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVA
                     EKGDSRPAGFTAGGNSREAVIRFPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAW
                     DAAHPEEGLKRDYDKAKAELDAEDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAE
                     ANKDDFVTYNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALT
                     GAMESRKQKEKKAKDAENKLNEEKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPK
                     TPKQGGGGKRARWYGDKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPK
                     RNIKKYL"
     CDS             complement(12127..13614)
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MMYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRT
                     QSRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMD
                     YAGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKIL
                     NAVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIR
                     FTEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWA
                     HQWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEF
                     GRFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLR
                     RRWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTT
                     WTKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
     CDS             14259..14504
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
     CDS             14778..15149
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
     CDS             15146..15511
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
     CDS             15686..15964
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
     CDS             15952..16221
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTV"
ORIGIN
        1 caccattatg tcccagacct gaattacccg gacctcgacc gtctccacca ctcataccgt
       61 tttcctcttt gacatttaaa acaataaatt aaagccaaca tgtcgcggta gggatacccg
      121 ttaccggata cccccgcaca gatcccggcg tgcgcgattt acgcaccggg ctcctgcctc
      181 gggtgtctgg cggtgaaccg ctccacaggc catggatgaa gaacccgaac ccttggtagc
      241 catgcggctg ccagtttgtt tgctttcgtc caggtcgtat catccttctg gctcctgcgc
      301 ctgagcgccc ggcgccagag gtttgttacg tgtgtcctga acttctgcat ggtggggaag
      361 ttgcccggta ccgagtgata gttcaggtat ccctgaacca ctctcctgag ccattttccc
      421 tgttcgggga ttgagtaatg ccagcgcctt cgcagaccgt ctttgatggc tttcagagtt
      481 gccgtcatcc gatcccggcg ggtctttcgt atcagcatga acctgccgtt gcgatctttc
      541 ccgctgatgt gcgtgaaccc gaggaagttg aacgtttctg gtttgccttt tcccctgatg
      601 gcacggtttt cggcagcgaa gcggccgaac tccatcagac gggttttctc cgggtgaacc
      661 gtgagtccga actccctcag tctgcgctgc atggctatac ggaagcgccg ggcatcgtat
      721 cgtttgtcga acccgatgac gatgtcatcg gcgtatctga ccattaccac attgcctgtg
      781 gcatagcgac gtcgccactg atgcgcccac agatcgaaga cgtagtggag gtatatgttt
      841 gccagcagcg gtgagatgac cgcaccctgt ggggtgcctt cctccgttgc tcgccattga
      901 ccctcctccg acgtcccggc tgtgagccac ttacgtatga gcctgattac cctccggtcg
      961 ccgatccgat gctctgtgaa cctgatcagc cattcgtggc tcaccctgtc gaagaactga
     1021 ctgatgtcgg catccagtac ccagtttacg ttagtgcgta ccagccctgt ggccagtgcg
     1081 tccagtgcat cgtgctggct tcgcccgggt ctgaacccgt atgagaaccc cataaagtcg
     1141 ttttcataga ctgcgttcag gattttcacc agcgcatact ggacgatctt gtcctccagc
     1201 gaggcgatgc cgagcgggcg ttgttttcca tccgcttttg ggatgtagtg acgcctgccg
     1261 ggctgcgccc tgtagctgcc ctgatgtagc ctccggtgca gatctgttat gttgttcttc
     1321 atgtttccgg cgtagtccat ccacctgatg ccatccactc cggcggccgc tttcctgctc
     1381 agggagagga atgcggcttc cagtgcttcg actgtcagca ggtggaacaa tgctgtaaac
     1441 cgttctttct tccgctgctt cgcagcttcc cgcacgcgtg acagcctctg tgacatgctt
     1501 tcccggctct gtgtccggcg catgtgtggc tgttccgcgt tccccttggc cccgctcctt
     1561 cgctccactg actccgctcc tttcgggttg ttcgcctgct tcgccgctac tatgagcgag
     1621 tccgacttct cctctccgta catcaccggc tatgactcct cgtcttcccg gtgcgggcca
     1681 tctccgacac tggcagatgg tcagagggga gatctcccgg ttcccgcgta gagatcgtat
     1741 tgacatgcca gggtctcaga ccccgccggg tccatgtggc actcgcagtg tcgcacccta
     1801 tgatgttgcc ttccgttaac agtacaacgt cggcacccgg taatttaata tacatttcgt
     1861 ggctcaatgg ctggcctgtc aacacccctg tcaacgcttc gccccatacc tcgcggtatg
     1921 caacgcatga ctcggggacc ttgtggattg ctggtccttc aatggtcggg gactttcacc
     1981 ccttgatctc taaccggtct cccggcgcac actgtacata tacacagtat aattattacc
     2041 ttactcctcc cgttttcagg tgtcaatata tgagattagt tctcatcttc aggcacaaaa
     2101 aagcgcccgg agccacctgt aagcagatcg cgtcttttcc cgaaaatttc tcatggcaac
     2161 aaattttatt atttaagaca ttcatcacac ttacatttca gatggtatag acacatctga
     2221 aagctaactg gcatgaggag aggacctgcg gttaaactgt tcgggaaacc tgagacgccc
     2281 ggaggccact atgacgcacc tgaaactgac tcccgctgaa gaaaagcgcc tggcggacgc
     2341 ctttgtcgct caggcactgg ccatgggcct gaaagggaac aaaacgctgc caaaggcggt
     2401 aaaacaacag gtgcgggaaa gggtgcttcg tgccattcag gacgaacgtg aagccaggcg
     2461 ggcgcaggaa atgcgtcggg agaaatacga ggctacggaa accaccttca cctggcagcc
     2521 acagcgccgc cggtaagggg tatttaccat aacgtcgcat tgcccgcacc gctcagacgg
     2581 tctgagggcg tttccggcgg ctacgggata aaacaggcaa caaaccaccc ggaaaaccgc
     2641 cggaaacgcg cccggtaaat tgtaacccgc tgcatgccta tgcacgcaac tgcatggcgg
     2701 gccgtttggt gtaaaaacga tacgataagc cgtgtttatg taaatgaacg tggccgtaaa
     2761 gagtgacaaa tatacatgta acatttttta ctgacaggtc atcaacccga tgcgtttaat
     2821 accctttatc ctgctggcat tgtgcagccc cttactcctg acggcctgta agcattccac
     2881 cacccagccg ccgaaaattt atactctgga taagtcatct aaaatcagta gctacgctgc
     2941 ggccatcaag accgctgttg aaatgcagat gtttgaacca gaggcctatg cgggaaaaat
     3001 gtgcaccgtg cggatatcca tacaacgtga tggcactctg aacagcgcca ttgctgaagg
     3061 aggagatccg aaactctgta aagcagcaat atcagccgtt acccacgcca aaattccgcc
     3121 ggcaccggat gaaaatacct ggcaaatatt caaaaacgcc cctctggatt tcagaccatg
     3181 aaagctttta ctctgacagt gctggcggcc atgttcctca ctccggtaca tgcgatacca
     3241 ctaaaacccg taaccacact gcagccaacc tacccggtac aggccgcagc aaaacgcatc
     3301 gaaggtcagg tgaccgccac gtttgatatt ctggacgatg gacgagtgga caacgtgtcg
     3361 cttaccggct gtcacctttt ttttcgggaa acgctgacgg caatgaggca ctggctatat
     3421 cccgcagggc acccggcaat gcgacaggtt ataaattttg aattcagtct gaaaaatgac
     3481 ggcttacagg atccgcgacc agtcaccacc caaaagctca atgatgatgg ttgccgccag
     3541 taacaggtcc tttaacccgc aggctgcaat agtcctggat gatgagtgag cctgtagcag
     3601 ccctgattag tggaagcgaa gctgaaaaat gggcagcaaa agccgtattt ctggcaaata
     3661 gcgccgccac ggattaaagt agtcatgtgt aatacatatg actacaaagg ggcttttatg
     3721 tcatcagcaa catccatcag gctcgatgaa gaacttaagg accggctgaa aacgctggcc
     3781 gatgaccggc accgctcagc gcacgcgcta atgctggagg caatcaccga atacatcgac
     3841 cgggaagaga agcgcagcca gtacctgcgg gacggacagg ccgcatggca gcactatcag
     3901 gaaacgggtc tgcaccttac tgcggaagaa gcggaagcct ggataagtac ctggggaact
     3961 gagaacgagc aggatgctcc gccatgccac aggtaacgat ttccgcgctg gcacagcgcg
     4021 atttacaacg ccttcaggac tttctcaaaa ccaaaaatcg gctggcagcc agaaaaggag
     4081 gtgaggtgat cgtccgggct atccagcaac tgaaaacatt gccagacatt ggccgcccgg
     4141 tgccgtttct gccgctggaa tataaggaac tggtgatcgg gtttggcgac agtggctatg
     4201 tgatgctcta ccgccacgac cgggaaatgg accagattgt gatcgtcacc gtcaggcatc
     4261 agaaagaatc cgggtatccg ggggcagaca gcctctaata accgatgacg ggggcgcaat
     4321 tcattgcgtg gccgtcgccg gtttgacaag cgcagcgcgt cagaaaacca catcctgaac
     4381 ggaaaaacgg gtaaaattca gcgatacatt taccgtgaga aattacacac ctttcacacc
     4441 cgataaaatc aggggtatac agtggcgaaa acattgctca acctttcaca ggcagcacaa
     4501 gccgcgggca ttaccagaag aacgctatac aatcatgtaa aacagggaaa ggttaccgtg
     4561 tcacgtgacg ggaaaaacaa ccctgtcgtg gatgtgtcag aactgatccg tgtatacgga
     4621 aatgtgaata tccctgagaa acaaattccc ggcatttcac accgtgaaaa tacacaaaaa
     4681 aatttcccac aggaacagct tctggcaatg caaaaggaac tggccgatct ccggcaggct
     4741 gtcaccctga tgctggaaga taaaacatcc cgggaagaag aacgccgcca gcacgatgat
     4801 gagcgccgga aactccaggc cgaagtggac agattgacaa cagaactgac acagaagaaa
     4861 aaacgcttct ggtccggctg gtttagctga gaacttaccg aagggaatgg agaacatgac
     4921 gaagcaggaa aaaactgccc tcaatatggc taaattcatt aaggatcagt cgctgctgtt
     4981 gctggaaaag ctgaacgagc tggacatgga taccccggcc gacatgtgcg aacggcttca
     5041 cgaggatgcg gaaacactct ggcaggtgat gcgggataag ctcggggaag aataacagca
     5101 ccggccatgc cggtgctggc gttatttttt gccgaacggc caccaccggc gggcgggttt
     5161 gtcctccggc agttcaggca ccggcacgtt aaaatagcgg ctgttatatt cccgcatcag
     5221 ctccgctttc agcttctcgt tcaccgcgct ttccccgtgc cgctcgctga ccacctcaat
     5281 catcgcgtta atctgctccg gtgagcactt cccggcatca accacctgca caccgttctc
     5341 gatggcgaac cgctccacct ttcgatagag gtaatcacac agcttcattc ctgtgggttt
     5401 gtcccgttcc cattgcggat tttcaccggt gaaaaagtac gtggcttttt cgtcgctgtt
     5461 gagccgctcg tcatacatcc cgatggattt catcatcgcc agatgctggg cccggtcgac
     5521 aaaacagaaa acatacgccc cggtctgcca ggcgagcacc accatgtctt ccagatgctc
     5581 gctggttggc ataatgcagc gctcgccgtc tttgtcttcc acgtcctcaa taaataccat
     5641 gtacagcgcc ataatccctc actccgttgt cataaattta aagcacgcga acagcctctc
     5701 ccggtccagc tccaccgttt tgcgggcctc gccggtctgt ggattcacga tttcatccac
     5761 cgccagaatc gcccgctgta cccggacaag cgtcggccgg tcagggcaga tgtaccagat
     5821 ttcatcgatg ccgttcgccc ggcggttgaa cagatacccg gacaccactt cctgataccg
     5881 cctgcggctc ttgacggtgc gctctacctc aaatgccacc gttctgccgt ccagctccgc
     5941 cagcgcgtcc ggcactttca tccctttcag ggccatacgg tgcaggtacc gccagccggt
     6001 ggccccccgg ccctccatgg agaggcgcag ggactgcacg gccagccggt gcggcagctg
     6061 cgccgccgac acccttgacg gctgaaacgg aataacgtcc gtcagcggct cgtcctcgtc
     6121 gaacgagaac gccaccccgt gcggcgtcag cccccacacg ctgacctgac ggccgtcaac
     6181 cgggtatttc gcccggacca gcagcccttt cgccaccaga ctgtccagga agcggtaaac
     6241 cggctgtacc gccgcaatcc ccagccgtcg cgcaaccagc tccgccgtgg aacacagctc
     6301 ttcccgcagc cagcgcaggg tcagccgtgt tttctccgcg ttccgcgcct gccgcttcgc
     6361 gtggctgacg ttgtactgct ccagtgtcat cagtaaagcc ccgcaaaatc atcatccgct
     6421 tttggtccgc cgccgtcggc cggaggcagg tactccgcca gcgggtccgt tttcgccagc
     6481 accgggaagg ttttcagcga aatttcccgg cgctcaaccc gcagcgggct gctgaacgcc
     6541 agccgcgcca cgcccagccc ggtcatcacc gcgaacccgt caggcaggtg ttgcagggtg
     6601 ttcacgtcaa acagcggccg cgcctccttc tggatgaagc tgtcgccgct gatgtgctcc
     6661 acgttccccg cctcccggct ggcccggcgg cgctccacgt ccacccggat ctccccggtc
     6721 tggcccgccg cccactgcgc ggactcctgg ctggccgcgc gatagaacca gcggatcggc
     6781 gtgttatcca gtaccgtggt tttcacaaaa tcagcgggca gatcctgccc gcactgaccg
     6841 aagtcgccca gcgactggtg cgcgagcagc aggttgcagt cccggctgcg cagcgtcccc
     6901 agcgcgttca gcacgtactt cgacagcaga tatttaatct catcgagcat gatgctcgcg
     6961 tgcggccacc tccggaactc atcccgcgca atgatgattt gcgcgcagcg ggcaaacagc
     7021 atcttctgca cccggatcac cgcctcatcg tccatcgagc cgatgacgta caggcagccg
     7081 ccgccgttga ttatccccgc cacatcgata ccgctgtccg tctgcaggac gctcaggtcg
     7141 gccacgttct ccagcttggt gatcagcccc ttcacgtcct ttttcagggc ctccggcaac
     7201 gcgtacgccg ccgccagcac ctgctgaatg tttgccccct gcgggaactg ctccgcaatc
     7261 agcttcgccg ctttctgctc gctgatgcgg tagtggtccg ccacgtcgcc ggtctcactc
     7321 aggttaaacc cggcaaccag cagattcttc agggcgtact ggtcgagatc gcggaacaga
     7381 ttcagctgcg ccggtttccc cggccgcaga tccagcaggg tgaagtccgg gcagtgcgcc
     7441 cggaagacgt gcggcgccca cgcgtcccct ttggggtcga agtacaccac agcgtccccg
     7501 aaatcgcgta cgcagcgaat gagcgcgttg gtggccatcg cgctcttgcc gctcccgggc
     7561 aggccgagga tctgaatatt ggtcttgcgc caggtatcac gagggaccag caccggctgg
     7621 ccctgctcat ccttacccag aaacaccgcc tgctgtttcc gggcctgctc cgtggaaaaa
     7681 tcggccagcg cgttaaccgg taccggctcc ccgaaatgca ggtggcggac gtctgtcatt
     7741 tctccggtcc gctggctgct gcgccggctc tcctgattca gtttcgcgtt caccgcctcg
     7801 tcagcggccg caaaatgacc atcaagcagc aggaacgcca gcagccgcgc cagaaggacg
     7861 ccggcgacaa gccctccggc acaccaggct atcccgaaca ggttagccgg ctgcagcagg
     7921 taataatctg cgttcgcata gaggtccggg cgcaggacgg tttctcccca gctctcgata
     7981 aacacggcga caaccagccc cccagaaggg ccagaccggc agcgccggtc agccagtacg
     8041 cgtagttcca gacatgtcgc cgtgccctga ccatccgccc gggtgaatcc agcgaggcca
     8101 gcaccgaaaa tggcacagtc cggttattat cgcgcttata gcgatcggca tactcccgcc
     8161 gcgccttatg gctcagcccc acaaaacgca ttcggccggc ccagagttca gccagaccga
     8221 aaaacaggcc gataaccaga aaaaaaccgg ccagactgta atactcccgg tacagccagc
     8281 tgacccacgg gtaaatctgc cgggccagct ccgggatatg ccactgccag gcaagcgaat
     8341 ccgtattaaa catgcaatct ctctccttca gacgacgggt ttaccggcgt gatgcgcagc
     8401 ccccgctgca caagccgcgg acatgcccca aggcatggcg gcggcggtca cgtccgtggt
     8461 gattgcgttc agctttcacc gcggaggcca gcctctttcc gccccatgcg gaaaaggcgc
     8521 agccccggag gaacaacgag cacgccccag cgtgtgagag gaaaaggcgg caccccagtg
     8581 cggtcttttc cggtgttccg gcccccgtca gagttcgcca tagcgagcgg ctgaccaccc
     8641 gcaaaatcag gagcagcttt gctgcttcgt caggtgcgtc cagcaccgtg gatttttgtg
     8701 ggtggtcagg cgtgagcctg acgggggccg ggtgaatttc tggcgtggcc ggcgtccagc
     8761 cggacagagc cagaaagagg ggaaaagacc gtgcgtcggt ggcgtccagc cagcgtaagc
     8821 aaggtctttt cccctgaagt cagccacgcc ccagcgggga tgacttgcat ttctccgcaa
     8881 ggagaaaaaa gcaacagaga taggttaacg taaaatgttc agcgaaaaac cgacatggtt
     8941 cacctatcct gataattgat cgtcagggaa tagaaagact taatcagggg acaatatccc
     9001 acatcagcgc gtccggtgac cgtcttgcag gtgccgggga aattgcgcct cctcgctcac
     9061 tcggtcgcta cgctccgggc gtgagactgc ggcgggcgct gcggacacat acaaagttac
     9121 ccacagattc cgtggataag caggggacta acatgtgagg caaaacggca gggccgcgcc
     9181 ggtggcgttt ttccataggc tccgccctcc tgccagagtt cacataaaca gacgcttttt
     9241 cggtgcatct gtgggagccg tgaggctcaa ccatgaatct gacagtacgg gcgaaacccg
     9301 acaggactta aagatcccca ccgtttccgg taggtcgctc cctcttgcgc tctcctgttc
     9361 cgaccctgcc gtttaccgga tacctgtccg ccgttctccc ttgcgggaag tgtggcgctt
     9421 tctcatagct cacacactgg tatctcggct cggtgtaggt cgttcgctcc aagctgggct
     9481 gtaagcaaga actccccgtt cagcccgact gctgcgcctt atccggtaac tgttcacttg
     9541 agtccaaccc gggaaagcac gcaaaacgcc actggcagca gccattggta actgggagtt
     9601 cgcagaggat ttgtttagct aaacacgcgg ttgctcttga agtgtgcgcc aaagtccggc
     9661 tacactggaa ggacagattt ggttgctgtg ctctgcgaaa gccagttacc acggttaagc
     9721 agttccccaa ctgacttaac cttcgatcaa accacctccc caggtggttt tttcgtttac
     9781 agggcaaaag attacgcgca gaaaaaaagg atctcaagaa gatcctttga tcttttctac
     9841 tgaaccgcga tccccgtcag ttcagaggag gacgatggtg ccaccgttcc gccctgaaca
     9901 tcccggatat aatttgcctg acatgcggcc agaagaaagc cagcaacaat caatataaaa
     9961 agaaaaatag tctttacctt tttcatatac tttccctgta tttaaagact ccggcattca
    10021 tccctgaaca ccggaagtca gtatttcaaa tcatccttga taattttttg ttaccagtta
    10081 ccgtcccgat aatcaaaagc tatataacaa ttatccacat caggttttat ttgattttta
    10141 aaaaatggct gtagtaaagg aacccattct ttcttcaaat caaactcacc attattaata
    10201 ttatccttta aaggcattcc caagctttca atgacagaac catcgtcacc aaagtcttta
    10261 gaatactctt cccctttaaa ctcttcagtt ttcttatcaa accatgtcaa acgtaattta
    10321 agccccatat ttacctctca aagatatttt ttaatgttcc gttttggatc tggcccttta
    10381 acctgcttac ccgttttggg atcaaatgcg cctaggtgtt cgccatcact ggcacgatac
    10441 ccttcaagct caccgtgctg ggaatcccat tcataaattt tacgtttttt atcgccatac
    10501 catcgggccc gcttaccacc accaccttgt ttaggtgttt taggatcacc tcgctttaac
    10561 tctccaagtc cctttatgtc ttctgtttta ggtactggat gataatcatg gccgtagtct
    10621 ttagtcccct tgcgaggctt gttcttttcc tcatttaact tattttctgc atccttcgct
    10681 tttttctcct tttgtttccg gctctccatc gccccggtaa gtgcagcctt atctctggat
    10741 aaggattcat tcattgcgtt taaagatgcc tgagccgctt ttaatttctc attctgattc
    10801 tgaatatcct tatcaagata gcgaacctga tcctgccacc cggagccata ttcatgaggc
    10861 gggttataag tcacaaaatc atctttattt gcctctgcct cttttacctt tttatcggct
    10921 tcctgaacag cagcccttgc accggggagc gccttctctg tcgatgcaat gcggctgttt
    10981 aaggtcgcaa tatttttatc ttcggcatcc agctcagctt tcgctttatc atagtctctt
    11041 ttcagcccct cttccggatg agcggcgtcc catgcctgct ggcgacgctt ttcttcctcc
    11101 tgacgctgtt ttacctgtgc cggggtaaga acatctgtca ccgacacata aaccggcttc
    11161 tgtccggtct ctttcgggaa acgaataacg gcctcacggg agttaccacc ggctgtaaaa
    11221 ccagccggac gtgaatcacc tttttcagca acaatgcctt ttggcggggc tttcgctgtc
    11281 ggaacacctt tcggtacgct cacctgcaga gacgggagac ccggaatcga cacactgaat
    11341 acccccggac gttttgtcgg tttcgcatcc accacaggga cactcattgg ccgacctgcg
    11401 acaaccgcaa tatgctgccg ctcatccttc accacatcca caacccgttg tctgacacga
    11461 accgtcgcct ggtccagtgg taaagtactt gccggagtct ccgtcaccgc atcggccggt
    11521 aatgacgtca taatttttga catcattttc ggatcatctt ttgcaatctc agaaggcagc
    11581 acaccgtaga tcgcaatccc ccacagacca aacttaaacg gccccttcag ggcagccagc
    11641 acatcagcaa cggcggccga caacgcatcg ccggaaactg ataaagccag tccttcagcc
    11701 cccggagtag ccagggcagg cagaccgaag gccatcgcag tggccgaaga ctgtccgcca
    11761 ccagagctac cgctatgatt gccgctgtta ccaccattac caccgggttt actcccgccg
    11821 ttaccaaact ccccggatta tagttatgaa tatctccatt cggcgtatgc gtcgtacccc
    11881 agcccggccc gctgtttgga tccgtaccac cacctgatga agggccacct ttaccagacg
    11941 taccgttcac attcccactg gcctgaccac cattatgtcc cagacctgaa ttacccggac
    12001 ctcgaccgtc tccaccactc ataccgtttt cctctttgac atttaaaaca ataaattaaa
    12061 gccaacatgt cgcggtaggg atacccgtta ccggataccc cccgcacaga tcccggcgtg
    12121 cgcgatttac gcaccgggct cctgcctcgg gtgtctggcg gtgaaccgct ccacaggcca
    12181 tggatgaaga acccgaaccc ttggtagcca tgcggctgcc agtttgtttg ctttcgtcca
    12241 ggtcgtatca tccttctggc tcctgcgcct gagcgcccgg cgccagaggt ttgttacgtg
    12301 tgtcctgaac ttctgcatgg tggggaagtt gcccggtacc gagtgatagt tcaggtatcc
    12361 ctgaaccact ctcctgagcc attttccctg ttcggggatt gagtaatgcc agcgccttcg
    12421 cagaccgtct ttgatggctt tcagagttgc cgtcatccga tcccggcggg tctttcgtat
    12481 cagcatgaac ctgccgttgc gatctttccc gctgatgtgc gtgaacccga ggaagttgaa
    12541 cgtttctggt ttgccttttc ccctgatggc acggttttcg gcagcgaagc ggccgaactc
    12601 catcagacgg gttttctccg ggtgaaccgt gagtccgaac tccctcagtc tgcgctgcat
    12661 ggctatacgg aagcgccggg catcgtatcg tttgtcgaac ccgatgacga tgtcatcggc
    12721 gtatctgacc attaccacat tgcctgtggc atagcgacgt cgccactgat gcgcccacag
    12781 atcgaagacg tagtggaggt atatgtttgc cagcagcggt gagatgaccg caccctgtgg
    12841 ggtgccttcc tccgttgctc gccattgacc ctcctccgac gtcccggctg tgagccactt
    12901 acgtatgagc ctgattaccc tccggtcgcc gatccgatgc tctgtgaacc tgatcagcca
    12961 ttcgtggctc accctgtcga agaactgact gatgtcggca tccagtaccc agtttacgtt
    13021 agtgcgtacc agccctgtgg ccagtgcgtc cagtgcatcg tgctggcttc gcccgggtct
    13081 gaacccgtat gagaacccca taaagtcgtt ttcatagact gcgttcagga ttttcaccag
    13141 cgcatactgg acgatcttgt cctccagcga ggcgatgccg agcgggcgtt gttttccatc
    13201 cgcttttggg atgtagtgac gcctgccggg ctgcgccctg tagctgccct gatgtagcct
    13261 ccggtgcaga tctgttatgt tgttcttcat gtttccggcg tagtccatcc acctgatgcc
    13321 atccactccg gcggccgctt tcctgctcag ggagaggaat gcggcttcca gtgcttcgac
    13381 tgtcagcagg tggaacaatg ctgtaaaccg ttctttcttc cgctgcttcg cagcttcccg
    13441 cacgcgtgac agcctctgtg acatgctttc ccggctctgt gtccggcgca tgtgtggctg
    13501 ttccgcgttc cccttggccc cgctccttcg ctccactgac tccgctcctt tcgggttgtt
    13561 cgcctgcttc gccgctacta tgagcgagtc cgacttctcc tctccgtaca tcaccggcta
    13621 tgactcctcg tcttcccggt gcgggccatc tccgacactg gcagatggtc agaggggaga
    13681 tctcccggtt cccgcgtaga gatcgtattg acatgccagg gtctcagacc ccgccgggtc
    13741 catgtggcac tcgcagtgtc gcaccctatg atgttgcctt ccgttaacag tacaacgtcg
    13801 gcacccggta atttaatata catttcgtgg ctcaatggct ggcctgtcaa cacccctgtc
    13861 aacgcttcgc cccatacctc gcggtatgca acgcatgact cggggacctt gtggattgct
    13921 ggtccttcaa tggtcgggga ctttcacccc ttgatctcta accggtctcc cggcgcacac
    13981 tgtacatata cacagtataa ttattacctt actcctcccg ttttcaggtg tcaatatatg
    14041 agattagttc tcatcttcag gcacaaaaaa gcgcccggag ccacctgtaa gcagatcgcg
    14101 tcttttcccg aaaatttctc atggcaacaa attttattat ttaagacatt catcacactt
    14161 acatttcaga tggtatagac acatctgaaa gctaactggc atgaggagag gacctgcggt
    14221 taaactgttc gggaaacctg agacgcccgg aggccactat gacgcacctg aaactgactc
    14281 ccgctgaaga aaagcgcctg gcggacgcct ttgtcgctca ggcactggcc atgggcctga
    14341 aagggaacaa aacgctgcca aaggcggtaa aacaacaggt gcgggaaagg gtgcttcgtg
    14401 ccattcagga cgaacgtgaa gccaggcggg cgcaggaaat gcgtcgggag aaatacgagg
    14461 ctacggaaac caccttcacc tggcagccac agcgccgccg gtaaggggta tttaccataa
    14521 cgtcgcattg cccgcaccgc tcagacggtc tgagggcgtt tccggcggct acgggataaa
    14581 acaggcaaca aaccacccgg aaaaccgccg gaaacgcgcc cggtaaattg taacccgctg
    14641 catgcctatg cacgcaactg catggcgggc cgtttggtgt aaaaacgata cgataagccg
    14701 tgtttatgta aatgaacgtg gccgtaaaga gtgacaaata tacatgtaac attttttact
    14761 gacaggtcat caacccgatg cgtttaatac cctttatcct gctggcattg tgcagcccct
    14821 tactcctgac ggcctgtaag cattccacca cccagccgcc gaaaatttat actctggata
    14881 agtcatctaa aatcagtagc tacgctgcgg ccatcaagac cgctgttgaa atgcagatgt
    14941 ttgaaccaga ggcctatgcg ggaaaaatgt gcaccgtgcg gatatccata caacgtgatg
    15001 gcactctgaa cagcgccatt gctgaaggag gagatccgaa actctgtaaa gcagcaatat
    15061 cagccgttac ccacgccaaa attccgccgg caccggatga aaatacctgg caaatattca
    15121 aaaacgcccc tctggatttc agaccatgaa agcttttact ctgacagtgc tggcggccat
    15181 gttcctcact ccggtacatg cgataccact aaaacccgta accacactgc agccaaccta
    15241 cccggtacag gccgcagcaa aacgcatcga aggtcaggtg accgccacgt ttgatattct
    15301 ggacgatgga cgagtggaca acgtgtcgct taccggctgt cacctttttt ttcgggaaac
    15361 gctgacggca atgaggcact ggctatatcc cgcagggcac ccggcaatgc gacaggttat
    15421 aaattttgaa ttcagtctga aaaatgacgg cttacaggat ccgcgaccag tcaccaccca
    15481 aaagctcaat gatgatggtt gccgccagta acaggtcctt taacccgcag gctgcaatag
    15541 tcctggatga tgagtgagcc tgtagcagcc ctgattagtg gaagcgaagc tgaaaaatgg
    15601 gcagcaaaag ccgtatttct ggcaaatagc gccgccacgg attaaagtag tcatgtgtaa
    15661 tacatatgac tacaaagggg cttttatgtc atcagcaaca tccatcaggc tcgatgaaga
    15721 acttaaggac cggctgaaaa cgctggccga tgaccggcac cgctcagcgc acgcgctaat
    15781 gctggaggca atcaccgaat acatcgaccg ggaagagaag cgcagccagt acctgcggga
    15841 cggacaggcc gcatggcagc actatcagga aacgggtctg caccttactg cggaagaagc
    15901 ggaagcctgg ataagtacct ggggaactga gaacgagcag gatgctccgc catgccacag
    15961 gtaacgattt ccgcgctggc acagcgcgat ttacaacgcc ttcaggactt tctcaaaacc
    16021 aaaaatcggc tggcagccag aaaaggaggt gaggtgatcg tccgggctat ccagcaactg
    16081 aaaacattgc cagacattgg ccgcccggtg ccgtttctgc cgctggaata taaggaactg
    16141 gtgatcgggt ttggcgacag tggctatgtg atgctctacc gccacgaccg ggaaatggac
    16201 cagattgtga tcgtcaccgt cag
//
