LOCUS       CP048291.1             21053 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  CP048291.1 Escherichia coli strain CVM N18EC0432 plasmid
            pN18EC0432-4, complete sequence.
ACCESSION   CP048291
VERSION     CP048291.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 15:51:36
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9777
            Orig. end    :: 30830
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11053]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             397..2298
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MEIVSFKVSQYRSISGEISSDNFNGLTIVGQNNSGKTNLLKAMRV
                     FFEGKFNPDLYDYEKDKPHGVKQGQTSFAVRFTFSESELDDVSEDLSQDDDDDDDDSII
                     ELGVLGEQEEPSNSISFDDGSSKQQESKPTQSRGRKLSLRDRYLQLFNMIDDSRLSSPQ
                     NEVTVHLTISNKNNYFYTVFKGYKRKPEVTSSMYTSVERRFIEKILSSFECVYIPSSKS
                     IDDIYHNLLVPYVRSEVASAMKTSVQVIHDKLLEVSEKITNEMILSGIDDCSFMIKAPP
                     SLDELFGRFEVSIKDTIENVISSKGMGLQCLSLFSSFKSISERKLTLGKKTIWMVEEPE
                     SFLHPSLGRSCNHIFKSLMDVAYVLITTHSLSFVSDEPSKIIELYKDDAGVTKDKKHEK
                     RFNAVASIRENLGVRFSDFFNISSSAVFVEGITDKQYIESILKLTSEHDEFKNRWPFLR
                     SAKVDEFGGVSQLGGFLKGCYEFISKDVPVISVFDGDEAGVKERTRLQSYFGKKQIRFE
                     SNKDYISVRSGFAIEGLFPDDFISDAMETHPSWFIGGKSVDADDVIEPFKVQDNKKTNL
                     LNFFLERCRVQPICGWISRWEKVFNVIDSALRDKSESITNKKRTEDTSGNTSDHQAA"
     CDS             complement(2524..3429)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 208.9; E-value: 1.3e-63)"
                     /gene_kind="other"
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWKDGRRSR
                     HSDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLE
                     RKTAVPPSKRAHTGKVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHWAVT
                     TGGFDSETVQDVMLGAVERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKNT
                     AVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSP
                     REYLRQQASNGLSDNRCLEI"
     CDS             complement(3387..3752)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQ
                     LFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVEYG
                     RAKKWIAHAPLLPGDGE"
     CDS             complement(4039..4218)
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MDFMSILGRCLLLPFPVAMFVGCLFLGIDDRFTGMFMSFIVGCLS
                     WYITKPKPQKAEVA"
     CDS             5145..6179
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MMIQSHPLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQR
                     KGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDY
                     DAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKIL
                     TRKQSRIYTYTLPEKWSDESINWNENKILRPKKLYKNNCAFYGSGKVEGRVIGGNLNTL
                     TGIWGSEWMPEIRNGDILFIEDSRKSIATVERLFSMLKLNRVFDKVSAIILGKHELFDC
                     AGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNISITEQYL
                     STEK"
     CDS             complement(6236..8005)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 134.7;
                     E-value: 4.9e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_19"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 3.5e-21, bitscore:
                     67.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQKITPSKIVKHARELIIKGIESGDNSFVIFDVDGALERLEHYR
                     CQLKSFFPNSSIAYSYKSNNLAQWCQIISGKGLYAEVCSVDEMNLAKRDGFNRIVFDGP
                     LKKTSELLKAIEIGALIEVDNIDECKRLNELCKLHKLTCRIHLRLSHYYDDNLSRFGLS
                     ESEAINLLEMLISKSEYLILDGFHLHVGSNLPNAEKICKAIIQYHELILRYMPDDGTLN
                     LGSGIPADSFSASSDNPTPCPEVFFSSIYDTIKNCFGTVCDKWNYIFEPGRHLVEDFGY
                     FIGKVISTKNRYGVKVAQTNIGINWIPSIRNWDHSFTLFHNHNHISDDKSDEYIIAGFN
                     CFECDCLFPSVILPSNLSDYLFSVRGCGAYDMQTGNQWTRNLYAVYTITNDVVNISRIH
                     RRELDFRKYDVSLTPSGIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVN
                     NISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQ
                     GKGIVTNAINKLIQEYGDSGVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNG
                     VSYDQNIYSKVIG"
     CDS             complement(7990..8793)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 60.2; E-value:
                     3.5e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MTIKHAEELTEEVILNMNYPDFVALMQQDNTPPGAEYTIDYWIKH
                     GCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKY
                     YVADACDLPFEDNSFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKIS
                     DKLINDVYNAINFRPNPLWTLEYWYQFFSERFTLVSEENHEMESQSEDELKADIYDYIF
                     NRNEFTKGLNGSLQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK"
     CDS             complement(8790..10004)
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MNTANILSVNYGAYNAIRMLIGVYHAAFLISTGVTISQLAVLQIV
                     FSVTVLILDFPLSVIADRFYRKQVVVSGVFFTILFYPLCIQSPDMLALVFSEIFYAIGI
                     CCISGAIEGWVLSALDGRNEKFTLCAHLCERVSSFGSVITGAVGILVVYFYDSYKSGYI
                     VSFFLMFVVFIVFLCVKTNGSGGEKEARDSIIKQAKESIGLITGSYNGTYFLSITCMFT
                     LGIQVIYHFWQPIMLSGESIGSLSKRELITLLMCHIGAFSMQYIANYLMPKIDVRCKLY
                     ILVCTLCSFLSSIACILLFMLITDNNVVLGVAIFSIIHGMISTIPVGAQNIFISRLNGN
                     YKNIISGALGLVSLSCRVASISVLGVISVLPGNMPVTTYIFISAIACVLCGCLFLMWSF
                     KKEMV"
     CDS             complement(10001..11053)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_22"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 2.2e-20,
                     bitscore: 64.5, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 9.5e-48, bitscore: 154.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYILGRYVKIARYGSGGLVGGGGKEQYVEDLALWENIIKTAYCF
                     ITPSSYTAALETVNIPEKDFSNCFRFLKENFFIIPGEYNNSTENNRYSRNFLHYQSYGA
                     NPVLVQDKLKDAKVVILGCGGIGNHVSVILATSGIGEIILIDNDQIENTNLTRQVLFSE
                     NDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKVPEADIWVVSADHPFNLINW
                     VNKYCVRANQPYINAGYVNDIAVFGPLYVPGKTGCYECQKVVADLYGSEKENIDHKIKL
                     INSRFKPATFAPVNNVAAALCAADVIKFIGKYSEPLSLNKRIGIWSDEIKIHSQNMGRS
                     PVCSVCGNRM"
     CDS             complement(12304..12711)
                     /locus_tag="ctg1_23"
                     /transl_table=11
                     /translation="MSLTLPLMYFQTGADLSKITHHEVHYQDGFVQQAWLQPEIQLFVV
                     CIARKKGSRREIKGGMAVLTSIPASNGAELAKALDNVMRQSDELRPLAGKDENVFIPAR
                     IGISGEEPPTEQELLSVFYQQCLKHGSWGSA"
     CDS             complement(12766..13230)
                     /locus_tag="ctg1_24"
                     /transl_table=11
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNVV
                     IEERREDAEREAAERAERERKRQELLQLIAGEGFSPEELLGLSEEAPKSRKKTLPKAPP
                     KYQFEENGETKYWSGRGRAPKPIAEALAGGRSLDEFIIKKDASSSAGDEQ"
     CDS             complement(13246..13452)
                     /locus_tag="ctg1_25"
                     /transl_table=11
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAADH
                     RRAELVMNKLYDKVPSGVWKYVH"
     CDS             complement(13449..15602)
                     /locus_tag="ctg1_26"
                     /transl_table=11
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHII
                     ESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHAGD
                     PDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKALARS
                     VADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFYYTMT
                     GVFQRGADVLRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDDKKTAA
                     PLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQFSEAPQV
                     IDALKSVFPQPLDIDSSRKSKAFNSAKVTAHTAIIPTSSVPDVNALSTDERNVYLAIAQ
                     HYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAEITDEGESEDNDDSA
                     FELLCKIRTGETLTTKEVVVNEKKTTPLPLFTEASLLAALVRVADFVTDPTIKKLLKDK
                     DKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDALPGIAVNPDM
                     TALWSEKQSAIENGDLTVEQFINELYGELTGMISDVDLGKMKIEPVAPAGQFQHLDSPC
                     PSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTDLIKGFKKKSGGT
                     YDTVLVLEDKKTGKLGFPARAKK"
     CDS             complement(15607..16182)
                     /locus_tag="ctg1_27"
                     /transl_table=11
                     /translation="MQYALFDGFERKFLLDALEFGVLKDWKENPVKELPDIDESAHPFH
                     VCYGGYLLNPGVSDSDISRKIKDQTGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGHQK
                     IVPFTALIKADECIISKIASYSGFAVTAFLRIKDQDIATNILNREGIFAFNGCERRFRH
                     PVSEDNWQQVISEERAIRCAKRLIQCKG"
     CDS             complement(16186..17448)
                     /locus_tag="ctg1_28"
                     /transl_table=11
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRKN
                     RKIYSNLDIEPVASTVVHTGSSPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIRFI
                     LNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKLGYYDGVYYHGKARKEE
                     IENAMRFSVHPKFDELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIAKALG
                     AKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGADTPRN
                     VAGTYVIFSTNYPKRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPEDVEIDLKE
                     LGAVLDRTTPAEIKEIINIAIGMIRGTKNELSVDVIKNARAFLKGTLDLSVQEADEDIE
                     EREELYKKNGAQPDYLSYLED"
     CDS             complement(17530..18039)
                     /locus_tag="ctg1_29"
                     /transl_table=11
                     /translation="MKIILITFIFLFTVFQSANAGGIPGVFTLNLEIQGKVIRVLDGDT
                     IEVLQDKQDKKPVRIRLANIDAPEKKQAFGCWSANQLKALLAAQPVTVTYTQRDRYGRI
                     IGRVFTTNGTDASRFMVKSGAAWVYERYNADESLPALQREAQEQKRGLWADSNPVPPWE
                     WRHKQN"
     CDS             complement(18118..18345)
                     /locus_tag="ctg1_30"
                     /transl_table=11
                     /translation="MKPLVYAMILSLTTFSAFAKQNSANSQKTGASNMERQSYENTDAG
                     KKQAEWMKGKLVKSDCSPAMNRIGWSEGCK"
     CDS             complement(18374..19699)
                     /locus_tag="ctg1_31"
                     /transl_table=11
                     /translation="MKVTKSIIAVLLCLSAGSAYADCEYYLTGNKETLNISDCVDGVKG
                     IANSALSNSQNAQNVANGAASTAQNAQSVANNAASTAQNAQTAANKVQTTANEANSAAQ
                     NALNTANTAQNTANSANTVAQNAQSTANQAIQDAAEKAEAAEKNANNYTDNKITDAKNE
                     LNTNIDSAKNDAINSSNNYTDSKISDTKTELNANIDKAKNDAISSSNSYTDSKISDTKT
                     ELNASIDKAKNDAFSSSNSYTDNKISDTKTELNASIDKAKNDAISSSNSYTDNKISDTK
                     TELNTNINNAKNEAISTSNNYTDKKYQQGISYTNEKYEQSIQYAQNAADKAEQNANNYT
                     DNRFSQLSNQSNQRFEQLNSKIERAEKRLNAGIAGVTAISSIPYVAENSFSYGIGVGNY
                     QNGNAIAAGIQYKTLLNTNVRLNVSWDSSHNTVLGAGFAGGW"
     CDS             complement(19800..20102)
                     /locus_tag="ctg1_32"
                     /transl_table=11
                     /translation="MKRICKGLIVIFTVSCFIAPTYAADPCKSVFCLYGKAVGSSGGSE
                     CSSAEKDFFKNVEKKKGKIRWGKTFDLRKNFLNQCSTADPAAISLIMSKFGRVRG"
     CDS             complement(20099..20512)
                     /locus_tag="ctg1_33"
                     /transl_table=11
                     /translation="MKKILMISILVLTACSSPPEPPQVEWEKMPEVMNTQIMNWKPTSG
                     VIKSDNINSPWSKVLPDFKPENHLYDDSVFYAVAHSEKIVVRTSSFDSYWSAKDWLRKN
                     GATGVIEYQPLKRWLNNDYVEIYLSRINIQRLL"
ORIGIN
        1 gaatcatgta atccaggtag cgaggactac accaattata tgcggttgca taatattgta
       61 agcctgacat cctcccctga attgcgaatc tatgcttttg atactcagtc caaagtatcg
      121 caatttatcc tgctcagaaa gcccaacgaa ccagaggtta ttgattcctg tcgcaatgcc
      181 gcgagaaacg ccgtttctgt gcttcagggg gcagtgagtg ctgaattgct tcaggataaa
      241 gcagcacttc aggacaaaca acatgcatgg tgggctttct ggcgaaaata aagcagaaca
      301 gtggaggaag agccatttct ccaagtagcg aaggacagtt aaagccttgg gaaaaaatgt
      361 cgataatccg agcaacattc tatcgtagga agaaaaatgg aaatagtatc atttaaagtt
      421 tctcagtata ggtctatttc aggggagata tcctctgata actttaatgg attaaccatt
      481 gttgggcaaa acaacagtgg taaaacaaac ctattaaaag ctatgagggt tttttttgaa
      541 ggaaaattta atcctgactt atatgactat gaaaaagata agccacatgg tgttaagcaa
      601 ggacaaacta gttttgctgt aagatttact ttttctgaaa gtgagctaga tgatgtctct
      661 gaggatttga gccaagacga tgatgatgac gatgatgact cgattattga acttggtgtt
      721 ttaggggagc aagaagaacc tagtaattct atttcatttg atgatggcag ctctaaacaa
      781 caagaatcaa aaccaactca atcaagaggc agaaagctaa gtttgagaga tagatatttg
      841 cagctattta acatgattga tgactccagg ttaagttcac ctcaaaacga agtgaccgta
      901 catctgacaa tatctaataa aaacaattac ttctacactg tctttaaagg ttacaagagg
      961 aaacctgaag taacttcctc catgtataca tctgttgaaa gaaggttcat agaaaaaata
     1021 ctttctagtt ttgagtgtgt gtatatacca tcgtcaaaaa gtattgatga tatatatcat
     1081 aatctattag ttccatatgt taggagtgaa gtagcttcag ccatgaaaac atcggttcaa
     1141 gtgattcatg ataaactgtt ggaagtttct gaaaagataa caaatgaaat gattctaagc
     1201 ggtatagatg actgtagctt tatgattaaa gctccgccat ctcttgatga gttatttggt
     1261 cgctttgagg tttcaataaa agatactatt gagaatgtga tatcgagtaa aggtatgggg
     1321 ctacaatgct tatctttatt ttcttcattt aaatctattt cagagagaaa acttactcta
     1381 ggtaagaaaa cgatttggat ggttgaggag cctgagtctt tcttgcatcc ctcattaggc
     1441 cggtcatgta atcacatttt caaatcactg atggatgttg cttatgttct tattacaact
     1501 cattccttat catttgtcag tgatgagcca agtaagatca ttgagttata taaagatgac
     1561 gccggtgtta caaaagacaa aaagcatgaa aaaagattta atgcagttgc aagcataaga
     1621 gaaaatcttg gggtcagatt ttctgatttc tttaacatat caagtagtgc agttttcgtt
     1681 gaaggtatca ccgacaaaca atatatagaa tcaatattga aattgacatc tgaacatgat
     1741 gagtttaaga acagatggcc ttttctgagg agtgctaaag ttgatgagtt tggtggagtc
     1801 agtcaacttg gaggattctt gaaagggtgc tacgagttta tttctaaaga tgtccccgta
     1861 atatctgttt ttgacggtga tgaagctggg gtcaaagaaa gaaccagatt acaaagctac
     1921 tttggtaaaa aacaaattag atttgagtca aataaagact atatttctgt aagaagtggt
     1981 tttgctattg aaggcctctt ccctgacgat ttcatttctg acgcaatgga aacccatccg
     2041 tcgtggttta tcggaggaaa atctgttgat gccgatgatg taattgaacc attcaaagtg
     2101 caagataata aaaaaactaa cttattaaat ttcttcctgg aaagatgtcg tgttcaacct
     2161 atatgcggtt ggatttctcg gtgggaaaag gtgtttaacg tcatagactc agccttgcga
     2221 gataaaagtg aatccatcac aaacaaaaaa cgaaccgaag atacttccgg taacacttca
     2281 gatcatcaag ctgcataatc gattgtgtac accaaggttg cacatacacc tgattaatca
     2341 agagtgagac cataacaagc ctatatcaga taacagccct cttcataaga gggctgtctt
     2401 tttcgcgggc atcgtacttg ggtttcactt ggaaaatgga aaacatccta cgctaagagc
     2461 gttttttaaa caaccggctt gttggttttt acgagatact gtgcagttga agtggatttg
     2521 cccctatatt tccagacacc tgttatcact taacccatta ctggcctgct gccgcagata
     2581 ttcccgtggc gagcgataac ccagtgcact atgcggatgc cattcgttat aatgctcgaa
     2641 cgcctctgca aggttctttg ctgccgttaa cccgtctggt ttaggcatga tactgatgta
     2701 gtcacgcttt atcgttttca cgaagctctc tgctatgccg ttactctccg gactccgcac
     2761 cgccgtgttc ttcggttcaa gccccaacat ccgggcaaac tgccgtgttt cattagcccg
     2821 gtagcatgaa ccattatccg tcagccactc tactggagac gccggaagct cgttgccgaa
     2881 gcggcgttcc accgctccca gcatgacgtc ctgtactgtt tcactgtcga agccgcccgt
     2941 agtgactgcc cagtgcagtg cctcacggtc acagcagtcc agcgcgaacg tgactcgcag
     3001 tttttctccg ttatcacagc ggaactcgaa cccgtcagag caccatcgtt gattgctttc
     3061 tttcacggcc actttgccag tatgtgcccg tttcgatggc ggtacagcgg tttttcgctc
     3121 aagcaacagc gcattctggc gcatgatccg gtaaacacgt ttggcattga tcgcaggcat
     3181 accatcaagt tcggcctgtc tgcgaagcag cgcccatacc cgacgataac catacgtggg
     3241 cagctctccg ataacatggt gtatacggag aagcacatcc gtatcatctg agtgacggct
     3301 gcggcgacca tctttccagt catcggttcg tctgagaatt acgtgcaact gcgcacgcga
     3361 cacccggaga caacggctga ctaagcttac tccccatccc cgggcaataa gggcgcgtgc
     3421 gctatccact tttttgcacg cccgtattca acggcttctt taaggagttc attttccatc
     3481 gtttttttgc cgagcaggcg ctggagttct ttaatctgct tcatggcagc agcaagttca
     3541 gaggcaggaa cgacctgctc tcctgcggcc acagcagtaa gacttccctc ctggtattgc
     3601 ttgcgccaga gaaataactg gctggctgcc acaccgtgtt gccgggcaac aagggagacc
     3661 gtcattcccg gttcaaaact ctgctgaaca atagcgatct tttcctgtgt agtacgccgt
     3721 ctgcgtttct ccggtcctaa gacatcaatc atctgctctc caatgactag tctaaaaact
     3781 agtattaaga ctatcactta tttaagtgat attggttgtc tggagattca gggggccagt
     3841 ctatgaagga acaagataaa ggaattaaag accctttagt accatacttt catgaaattt
     3901 tcccatattt tcttttagat cgtgcaacag cgaaaagacg taggaattgg cttgattagc
     3961 cgcaatacta tttctggaca gaatgagtgt atatccaagt cgggcgagga attaaacgag
     4021 gggcgtaaaa aaggccgctt acgcgacctc agccttttgc ggttttggct tggtgatata
     4081 ccacgataga caaccgacaa taaaactcat gaacattcca gtaaaacgat catcaatgcc
     4141 tagaaacagg caaccgacaa acatcgcaac agggaaagga agaagtaaac agcgccccaa
     4201 aatgctcata aaatccataa atcctccttt gttaaagggc aggaagcggt tcacttcctg
     4261 cccttagtta cgtttccgct gtcatcagtc gatgaactgg cgaatcagtt ccagaattgc
     4321 aatcagcgcg tttgcaacgg cgaccacagc cctgagaacg atgattaaca aattaatcat
     4381 ccgtttctcc agtaaaactg gaggaaatca ccgttgctta ctcatacact gcctgtcaca
     4441 acggctctct cgcattgtta ggtgtagagt gacctcctcc tgccagagca ccgaatacag
     4501 caccacctgt ttatccagcc aggactttaa aatcgttcat acccgcagat acgggaagag
     4561 caggattgca agtcaactac atgactaact gactgattat acgctacaca aaacacccgt
     4621 tacaccacta aatgtggttc cttaaccaca tttagttgct ttacagcacc atagtgaata
     4681 aaatgtaaac gttaggtgta gagtaacctt ctccagtcag agccaccaac tcagggctgg
     4741 aaaacacaaa aaagcccgat taccagtcgg gtttttttgt gcctgtcgtt cggctgtact
     4801 tccgtttttt ccccttcatt tgagggattt ttctttcatt ttttgttgcg gccaatactg
     4861 ctgatcgcgt tggccaacag atcaatgccg ttatcggcgt tttcatgaat ccattttttt
     4921 cagtaagttg cagcacaaca gatgattaaa aaagctatca gtttttttga tggatacagt
     4981 agtggcggtg cgctacgtga aatctgaggc ttttcggggg ggattggacg agaaaattta
     5041 cgagagaaca ctgcgatttt caaaaaaagc ccataaactg aaagtgctac tgacatatct
     5101 caaaacgggt tcattttgac actaaatgga aaggaaaaat cctcatgatg atacaatctc
     5161 atccactact ggccgctccc ctggcagtag gagatacaat tggtttcttt tcatcatctg
     5221 ctccggcaac agttactgca aaaaatcgtt tttttcgggg agttgagttt cttcagagaa
     5281 agggatttaa gctggtatca gggaagctta ccggtaaaac agatttttat cgttcaggta
     5341 ctattaaaga aagagctcaa gaatttaatg agttagtcta caatcctgat attacctgta
     5401 taatgtcaac gatcggtgga gataacagta attcactgct accgtttctg gactatgatg
     5461 ctatcattgc aaaccccaaa attatcatag gttactcaga tacaactgct ttattagcag
     5521 gaatatatgc aaaaacaggg ttaataacat tctatggacc agctcttatt ccttcgtttg
     5581 gtgaacatcc acctcttgtg gatataacat atgaatcatt tattaaaata ctaacaagaa
     5641 aacaatcaag aatatatacc tacacattac ctgaaaagtg gagtgatgag agcataaact
     5701 ggaatgaaaa caagatatta aggcctaaga aactatataa aaacaactgt gccttttatg
     5761 gttccggaaa agttgagggg cgtgtaattg gaggaaatct aaatactttg acaggtatat
     5821 gggggagtga atggatgcct gaaattcgga atggagatat attgtttatt gaggacagtc
     5881 ggaaaagcat tgcaacagtt gaacgattat tctctatgct aaagcttaat cgcgtgtttg
     5941 ataaagttag tgcaataata ctcgggaaac atgagctttt tgattgtgca ggaagtaaac
     6001 gcagaccata tgaagtatta acagaggtat tagatgggaa acagattcct gtactggatg
     6061 gatttgattg ttcacataca catccaatgc taactcttcc acttggtgta aaattagcta
     6121 ttgactttga caacaaaaat atatctataa cagaacaata tctatctacc gagaaataaa
     6181 tattatcatc tcacagacat aaacaaaatg gcgtagaata ctacgccata cagcattaac
     6241 caattacttt tgaataaata ttttgatcgt atgatacacc gttgagtatt tctgcttttt
     6301 gcagaacacc ttctaaggtg aagccacacc tcaatgccgt ggcattactt tttttattat
     6361 caacaataca ttttataaca aatcttttta taacgcccga atccccatac tcctgtatca
     6421 gtttatttat ggcattggtt acaatcccct ttccctgaaa gttagcgcct aaccaatagc
     6481 caatatatgc tgttttattg gcatggtcaa taatattaaa cgatacaacg ccagctatct
     6541 tagttttgta tttaataaag aggattaatg ctttttcatt ctggttatca atcattgatt
     6601 gctcaatgaa agaaacagaa tcagaaatgt tattaacaaa cgctggccat gccatgcttt
     6661 taatgaaatt tattttgttt tgattaatga gcaaatataa ctcttcagcg tattttaacg
     6721 ctggatacaa taatgtaatc tcatcattta cttttattcc tgatggcgta agagatacat
     6781 catacttccg gaaatcaagt tctcttctgt gaatccttga tatattaaca acatcatttg
     6841 ttatggtata tacagcataa agattacgcg tccactggtt tcctgtttgc atatcataag
     6901 caccacaccc tcgaacagaa aataaataat cagataagtt actgggaaga ataactgaag
     6961 gaaacaagca atcacattca aagcaattga atccagcaat aatatactca tcagatttat
     7021 catctgaaat atggttatga ttatgaaaca atgtaaatga atggtcccaa tttctgatcg
     7081 aaggtatcca gtttatacca atgttagttt gagcaacttt aacaccatac ctgtttttag
     7141 tactaataac tttccctata aagtagccaa agtcttcgac cagatgtcta cctggttcaa
     7201 aaatatagtt ccatttatca catacagtac cgaagcaatt ttttattgta tcatatatcg
     7261 atgagaaaaa tacctccgga catggagttg ggttatcact ggatgctgag aaagaatctg
     7321 caggtatccc actaccaaga ttaagagtgc catcatctgg catataccta agaatcaact
     7381 catgatactg tataatagct ttacatattt tttccgcatt gggtagatta gagccaacat
     7441 gtaaatggaa cccgtctaaa atgagatact ctgacttact gatcaacatc tccagtaaat
     7501 taatagcctc actttcagat aagccaaatc ttgataaatt atcatcatag taatgcgata
     7561 atctcaaatg aattctacat gtcaacttat gcaatttaca tagttcatta agtcttttac
     7621 attcatcaat attgtcaact tcaattaatg ccccaatctc tattgccttt aatagttcac
     7681 tcgttttttt taaagggcca tcaaaaacaa tccggttaaa accgtctctt ttagcgaggt
     7741 tcatttcatc aacagagcac acctctgcat acaaaccttt acctgagata atctggcacc
     7801 attgtgccag attatttgac ttatatgaat atgcgatact gctgttgggg aaaaaactct
     7861 taagttgaca cctgtaatgt tccagacgct ccagagctcc atctacatca aaaatgacaa
     7921 atgagttatc acccgattca atccccttaa taattaactc ccgggcatgt ttaacaattt
     7981 tagatggtgt tattttttgc gccatatttg caatgtaact ccctgataat ctctttggat
     8041 atttaatggt ctgcgtattt ttaaaaatct ttcaaaaaat acattctgaa gtgaaccatt
     8101 caaacctttt gtaaactcat ttctattgaa aatgtaatca taaatatcgg cttttaactc
     8161 atcttcactt tgagattcca tctcatgatt ttcttctgaa accagagtaa atctttcaga
     8221 aaaaaactga taccagtatt ccaaagtcca caaaggattg ggtctgaaat ttattgcatt
     8281 atatacatca ttgataagtt tatctgatat tttacgcctg taataaaaat ttgaaatgca
     8341 catgcttccc atgtggttta aacatcgatg agtttcattc aaagctatta accgattttg
     8401 tataaatgca aaattacatc caccgagaac atgtgtaaaa gagttatctt caaatggtaa
     8461 atcacaagca tcagctacat aatatttcaa taaattatta gccttaagct tttttgcctt
     8521 ttcatttgcg accattacag ctgattcaga tatatcaata ccctctgcag atgcaccttc
     8581 ttttttgaag cattcacgtg aactaaaacc cgtggaacat gctaaatcta ataggtgaga
     8641 ctttttgtta atacatccat gcttaatcca gtagtctatg gtgtactctg ctccaggagg
     8701 agtgttatcc tgttgcatca gagcaacaaa atcagggtaa ttcatattta aaatgacttc
     8761 ttccgtcaat tcttcagcat gtttaatcgt cataccatct cctttttaaa ggaccacatt
     8821 aagaacaaac aaccacacag tacacatgca attgcagaga taaatatata agtggtgaca
     8881 ggcatattac ctggtaatac agatataact cccaacacag aaatggaagc aacacgacat
     8941 gaaagagaaa caagaccaag agctcccgaa ataatattct tataattgcc attaagtctg
     9001 cttatgaata tattctgtgc tccaacaggt attgttgaaa tcatcccatg gattatagag
     9061 aaaatagcta caccgagaac aacattatta tctgttatta acataaatag taaaatacag
     9121 gcgattgaac taagaaatga acataatgta caaacaagta tataaagttt acaccttaca
     9181 tctatctttg gcataagata gtttgctata tattgcattg aaaatgcacc aatatgacac
     9241 atcagtaaag ttataagctc tctttttgat aatgagccaa tactttcccc agataacata
     9301 attggctgcc aaaaatgata aattacctgt ataccaagtg taaacataca tgttatagat
     9361 aaaaaatatg tcccattata acttcctgtt atcaatccaa tactctcttt tgcttgttta
     9421 ataatactat ctcgtgcttc tttttcaccc ccactgccgt tagtttttac acataaaaaa
     9481 acgataaaga caacaaacat caagaagaac gatactatat agccagattt ataagaatca
     9541 tagaagtaga caactaatat tccaacagca ccagttatca cactcccaaa ggaagatacc
     9601 ctttcgcata aatgagcaca taaggtaaat ttttcatttc taccatccag agcacttaac
     9661 acccatccct ctatagcccc agatatacaa caaataccaa tggcataaaa tatttcagaa
     9721 aaaaccaatg ccagcatatc aggagactga atacaaagag ggtaaaataa aatagtaaaa
     9781 aatacgccac taactacaac ctgtttcctg taaaatctgt ctgcaatgac agataaagga
     9841 aaatcaagaa tcagcactgt cacagaaaaa acgatctgta aaacagcaag ttgagatata
     9901 gtgacacctg tagatataag aaatgctgca tggtagacac caattaacat acgtatagca
     9961 ttataagctc catagttcac agataaaata tttgcagtat tcacattcta tttccacaca
    10021 cagagcaaac aggcgaacgg cccatatttt gggaatgtat ttttatttca tctgaccaga
    10081 tgcctattct tttattaagt gataatggct cggagtattt tccaatgaac ttaattacgt
    10141 ctgccgcaca taatgcagcg gcaacattat tcacaggtgc aaatgttgct ggtttaaatc
    10201 tgctattgat tagcttaatc ttatgatcaa tgttttcctt ttctgaacca tatagatctg
    10261 ccacgacttt ttggcactca taacatcctg ttttaccagg aacatataat ggaccaaaga
    10321 ctgcaatatc attaacatac ccagcattta tatagggctg atttgctcta acgcaatatt
    10381 tattaaccca gttgatcaga ttaaatggat gatctgcaga aacaacccat atatcagctt
    10441 ctggtacctt atgaagatca gtgtaatcgt ttatattcaa agcgatttca gacaccgaaa
    10501 tttcagagtt tctttttaat aactcgcgtt ttataacttc tgttttattt ttaccgacat
    10561 cattctctga aaataaaacc tgccttgtca aatttgtatt ttctatttga tcattatcaa
    10621 ttagtataat ttcgccaata ccagacgttg cgagtataac agatacatga tttcctatac
    10681 ccccacaacc aagaattact accttagcat cttttagttt atcttgcaca agaacagggt
    10741 tagcaccata actttgataa tgtaaaaagt tacgagagta acgattattc tcagtagagt
    10801 tattatactc accaggtata ataaagaaat tttccttaag gaacctaaag caattagaga
    10861 aatctttttc aggtatattg acagtttcca acgctgcagt ataactcgat ggggttatga
    10921 aacaatatgc ggtttttata atattttccc aaagcgctaa atcctcaaca tattgctcct
    10981 ttccgcctcc accaactaat ccaccgctcc cgtatcgagc aattttgaca tagcgaccca
    11041 atatataatc cataaataaa cctcgcagat aaattttgta tgccaccctg tacagggtgg
    11101 catttaatgg acatttatat tttgccatta gtttgcatta ccagtacgca ttctacgcct
    11161 cctattactg tgattaattc acaagtgttt ttatcactat aaaaaacaat attcctcatg
    11221 aaaatataca aacatagatt catttcacaa aaaaagaaca gcacaatcat attatttgcg
    11281 gttatacatt tttattctaa aatttattaa tttatatatt tagacataaa taaccataca
    11341 gaatataatc atctacgttt aaaccatttt gtactaaaaa tttgatacat ccatcgttca
    11401 ttacattaga aaccaataat cctgattacc agtcacgttg agaagccact caatgagcgg
    11461 tggtgcgcta cgtgaaatct gaggtttttc gggtcggatt ggacacgaga atttatgaga
    11521 aagaatcagg aaatgccacg aaaatggaga ttaattttcg atgaaaggca gctcgcaatc
    11581 accgcattca atattcactc cggacttccc ccagacagca gcaccacacc ccgacactga
    11641 tatttgactt tgttcctttt tagcttgtcc tcaaaagccg caacaaacag atcgttatca
    11701 ttgctcccgt tctacggtga cactgacagc accggcttcg atatcaatcc cggttcagca
    11761 ttttgatgtg cttgagcaag tagtttcccg ccattgatcg atgacggcgg ccatctcttt
    11821 tagttgttca acctggacag ggaagcgatc aaaccagctc aaagcaaatt taccctgaaa
    11881 cagttccagt gtgacgcgct ggaacgtaat cagacactcg gggagttcac cgtcaaaaag
    11941 gcgctggtcc tggttataga aatcaaacgc ctattgtagc tcgctgtagc gcgttctgtg
    12001 gctatcgtca tcatcgacaa cccagcattt cgcgccgtca tattcattgc cactttctgc
    12061 aataaacacg ttctcttcag tatctaccgc tatcactctg gggcgctcat gctgaggggc
    12121 gcggagaata tttttccagc aatacacctt cccgtcccaa atcagaatca cacccgaatc
    12181 tgcgtgctcc gggttgtgct gacgccatac cctggcaata tcaagcctag gaagagcctc
    12241 gagcgcgtaa tattgctggc aagaaaggta agcagggggt atccctgctt tatgtaccag
    12301 aaatcaggca ctgccccatg agccatgttt caggcattgc tggtaaaaga cacttagaag
    12361 ctcttgctct gttggcggtt cttcgccaga aattccaatt ctggctggga taaatacgtt
    12421 ttcgtctttc cctgccagtg gccgcaactc atcagactgg cgcataacgt tatccaacgc
    12481 ttttgccaac tccgctccat tgctggccgg aatactggta agaacggcca ttccaccttt
    12541 aatctcgcga cgggagcctt ttttcctggc gatacacaca acaaatagct gtatttcagg
    12601 ttgcaaccat gcctgctgaa caaagccgtc ctgatagtgc acttcatgat gtgtgatttt
    12661 gctgagatct gcacctgtct ggaaatacat taatggtaat gtcagactca aaacatcctc
    12721 ctgtttatca aaaaagtctc ctgcgtaaac cagaagctta ttatattact gttcgtcgcc
    12781 agcagagctg gaagcatctt ttttgatgat aaactcatca agagagcgac cgcctgccag
    12841 tgcttcagct atcggttttg gcgcacgtcc acgaccagac cagtatttcg tttcaccatt
    12901 ttcttcaaat tgatacttgg gtggcgcttt tggtaacgtt tttttacgtg attttggtgc
    12961 ttcttcggac agaccaagca gttcttccgg tgagaaaccc tctccggcga ttaactgaag
    13021 cagttcctga cgtttccgtt cacgctctgc tcgttcagcc gcttcacgtt cagcatcttc
    13081 acgacgttct tcaataacaa cgttgagctt ttcctgcatt tcgagcaact gctcaaaatc
    13141 aatctcacgg gcaaacacac gcaatgaacg aatattcatc atagtccggc tgataatgcc
    13201 gtattcatct tctttagtca gttcgctcat aattaatcct cttgtttaat ggacgtactt
    13261 ccatacgccg gaaggaacct tatcataaag tttattcatc accagttctg cacggcggtg
    13321 atctgcggca gaataaaatg cctctgattc tgataaaggc agcttgtaac ggttaatctc
    13381 aataactttt tcaagagtat ctcttgatgt acattttctt aactgaaaaa gccattcctg
    13441 ctttgttttc acttcttagc ccttgccgga aaacccagct tccctgtttt cttatcctca
    13501 aggacaagaa ctgtatcata cgttccacca cttttctttt taaatccctt aatcaaatcg
    13561 gttttccctg atttaaccag tttttcggcc tgtgcctggg tgattttctt accagaaaac
    13621 tcactccaga ttttaaattc acatccggta cagaaataac ctttcggcct gataacaata
    13681 tgtttaccac aggaagggca gggagagtcc aggtgttgaa actgccctgc tggcgcaacg
    13741 ggttcaatct tcatcttgcc caggtcaaca tcagaaatca tgcctgtcag ttcaccgtac
    13801 agctcattaa taaactgttc aaccgtcagg tcgccatttt caatggcaga ctgtttttca
    13861 gaccataatg ctgtcatatc aggattaacc gctatacctg gcagggcatc aataagcgca
    13921 tatccggtat cagtcggaat aagtttccct ttttccagcg tgatatagtt tctcttcttc
    13981 agcgtttcca gaatggctgc acgggtagct ggcgtaccaa taccgccatg ttcatctttt
    14041 ttgtctttat ccttatcttt cagtaatttt ttaatcgtgg gatcagtgac aaaatccgcg
    14101 acacgaacaa gcgcagcaag caaggaggct tcggtgaata acggcagcgg tgttgttttc
    14161 ttctcattaa caacaacttc ttttgtcgtc agtgtttctc ctgtgcgaat tttacagagc
    14221 agttcaaaag cggaatcatc attatcttct gattcacctt cgtctgtgat ttccgcgcca
    14281 agaaacgcct caaatccgct gtcagttgtt tttctggcac gggcatagaa cgactcatca
    14341 ccacactgaa tggcaaccga tacttcctgg tatgcttttt caggcatgaa ctgaacaaga
    14401 tagtgttgtg cgatcgccag gtaaacattg cgctcgtcgg tgctgagtgc gttaacatca
    14461 ggcacactgg aggtcgggat tatcgcagta tgcgcagtca cctttgcact gttaaacgct
    14521 ttgcttttac gtgaagaatc aatatccagc ggctgaggaa agactgattt cagggcatcg
    14581 ataacctgcg gcgcttcact gaattgttca tcagaaagat atgagcaatc tgagcggtta
    14641 taagtaattg ctttatattt ttcacgtagt tgttgcgtaa tatccagcgt tttttgtgcc
    14701 gtcattttaa acttcttgtt catgtattgc tggagtctga ccaggttaaa cggcaacggc
    14761 gcagccgttt ttttatcatc agttgctgct gcttcaactg tagccggttt tcctgcaagg
    14821 gatgctgccg ttccgtctgc ccacgcctta tcaagtaatt tacggtcggt cagcggagca
    14881 aattcacctg gtttccagtt cgccctgaga acatcagcac cacgctgaaa aactccggtc
    14941 atggtgtagt aaaaactgga tttatggttc tggttagcac gggtacgatt cacaatcagg
    15001 ccaagaacgg gtgtctggac gcgcccgaca gacagaacgc cctgatatcc tctggctttt
    15061 gcaggaatgg tgtaagcacg cgtcatggag aatccataga cggcatcggc aactgaacgc
    15121 gccagcgcct taaggtaaag ccctttgaaa tcacgattat ctttaagatt tgccagtgcc
    15181 tttttcactg ccggaagcgt gttgtcgttt atcagaacgc gcttcacggg ttttgtgttt
    15241 cctgcatatt ccaggacttc atcaacaagt agctgtccct catcatcagg atcgccagcg
    15301 tgaacaattt cagtcacgtc tccacgtctg ataagttcga gaatcgtttt aacctgtttt
    15361 gctgcacttt caacaggctg atacttcacg ggataaagac gtaaaggaag cgtttcaacc
    15421 ttccaggctt tgtattcagg attatagttt tccggcggtt gtgattcgat aatatgacca
    15481 aaacagttcg tcacaatggc gttatcactt tcaaaccagc catcatggcg ggtaaaattg
    15541 ccaccaagtg ccttaacaat atcatttgct actgcgggtt tttctgcgat aaaaagtctc
    15601 attttgttat cctttacatt gaattaatct ttttgcacaa cggatagcac gttcttctga
    15661 tattacctgt tgccagttat cttcacttac tggatgtctg aatctgcgtt cacagccatt
    15721 aaaagcaaaa atcccctcac ggttaagtat attcgttgcg atatcctggt ctttaattct
    15781 caaaaaggct gttacggcaa aaccagaata cgaagcaatt tttgaaatga tgcattcatc
    15841 agcttttatt aacgctgtaa aaggaactat cttctgatga ccacacgaaa ttaaagggag
    15901 ggtgtgaata tcataataag ctattgaatg acaatccata cgggtatcat caatagctgc
    15961 cagccagaat cctgtctggt cttttatttt tctgctaata tcagaatctg atacaccagg
    16021 gtttaataaa tatccaccat aacagacatg gaaggggtga gcagattcat caatatcagg
    16081 aagttctttt accggatttt ctttccagtc tttcagaaca ccaaattcaa gagcatccag
    16141 caaaaacttt cgttcaaatc catcaaacaa tgcatattgc atgtgttaat cctccaggta
    16201 acttaaatag tcaggttgcg ccccgttctt tttataaagc tcttcccttt cctctatatc
    16261 ttcatctgct tcctgcacgc tcagatcaag ggttcctttc aaaaaggcac gagcattttt
    16321 tattacatcc actgataatt catttttggt tccgcgaatc attccgattg cgatattaat
    16381 aatttccttg atttcagccg gagtcgttct gtccagcact gcgccaagct ctttaaggtc
    16441 aatttctaca tcttctggta agtacatttt ggcgcaagcg gcagcggctt tggttctgaa
    16501 agcacctaca gagattatcc tgtcaattcg acctggacgt tttctaatac gtgggtcgat
    16561 acgttttgga tagtttgtag aaaagatcac atatgttcct gcgacatttc gcggtgtatc
    16621 agctccatca agaaaactta acgttccggc atcagcccga taaagttcat caacctcttc
    16681 agctataata atgacgggta ttttcttctg agcagcagcg tagcaaacat ctttaaagta
    16741 atcgtcggca taaacaaaaa catacttatc ctgatacttt gcccccaaag cttttgcgat
    16801 agttgtcttg cctgttcctg gggggccagt aaagagcact ttacgcatac ctgactgacc
    16861 ataccgggta tagaaatcaa tatcagaaaa gaactgatta aagtcgtttt ccagctcgtc
    16921 aaattttgga tgaactgaga aacgcatagc attttcaatt tcctcctttc ttgccttacc
    16981 gtgataataa acaccatcat agtacccaag tttccagata cctttacgtg gtaatgagcg
    17041 gtttaattta gcgcgacctg cctcgcaaag attgtggagc attgacatac ttttagtagt
    17101 cccaacggcg tactccatcc tgactttaga gttaagaatg aagcgaataa tatgaacaac
    17161 ttcattttga ccaagatgaa tcctgtatgc accagaacca tctttgaaca taagtttttt
    17221 aattctcccg gctttagcca taacagggct acttcccgta tgaacaacgg ttgaagcaac
    17281 aggttcgata tccagattcg aataaatttt acggttcttt ctgtttataa aaatctctgc
    17341 cactttagga tagtaatcac aatcctttac gacagttcca aaattatctt caccgtaata
    17401 ttctttgtga agccgtaaag cctgctctac cagagttaat ttacccataa gcgcaccatg
    17461 tatatttaaa accgtgacac tgcctgaaat ttatttaagg tagtggaggg gttggacaag
    17521 caacgcgcgt cagttctgtt tatgtcgcca ttcccacggt ggaaccggat tactgtcagc
    17581 ccataaacct cgtttttgtt cctgcgcttc ccgttgcaga gccggtaatg actcatccgc
    17641 gttgtaacgt tcatataccc atgcagcacc agacttaacc ataaagcggc tggcatcggt
    17701 gccgttcgtc gtgaacacac gaccgataat gcgtccgtag cggtctctct gcgtatacgt
    17761 cacagtaaca ggctgtgctg caagcagagc tttaagctga tttgctgacc agcacccgaa
    17821 agcctgtttt ttctccggtg catcgatgtt tgccaggcga atcctgacag gctttttgtc
    17881 ctgtttgtcc tgtaaaactt cgatggtatc gccatcgaga acacgaataa ctttcccctg
    17941 gatttccagg tttaatgtga aaacaccagg tattccacct gcatttgcag actgaaaaac
    18001 agtaaacaga aaaataaatg ttattaatat aattttcata aaatactaac gcccttcggt
    18061 tgttcaaccc cgcaaatcca gattaaaatc tgaaatctgc gaggttatca ttgatgatta
    18121 cttacaacct tctgaccagc caatacgatt catagctgga gaacaatcag atttaactaa
    18181 tttacctttc atccattcag cttgtttttt ccccgcatcg gtattctcat agctttgtct
    18241 ttccatatta cttgcaccag ttttctgact gttagccgag ttctgttttg caaaagcaga
    18301 aaaggtcgtc agtgacagaa tcattgcata aaccaatggt ttcattttta tctcctttca
    18361 catagataat ttattaccag ccacccgcaa aacctgcgcc aagtacagtg ttatgagatg
    18421 aatcccatga aacattaagg cgcacgtttg tgtttaataa cgttttatat tgaatgcctg
    18481 ctgcaatcgc atttccattc tgataattac caacaccaat accatatgag aaactatttt
    18541 cagcaacata cgggattgat gatattgctg ttacacctgc aataccggca ttaaggcgtt
    18601 tttccgcacg ttcaatttta ctgtttaatt gttcgaaccg ctgatttgac tgattgctta
    18661 actgactgaa tcggttatct gtatagttat tcgcattttg ttcagcttta tcggctgcat
    18721 tttgagcata ctgtatgctt tgctcatatt tttcattggt ataactgata ccttgttgat
    18781 atttcttatc cgtatagttg tttgatgtgc tgattgcctc attttttgca ttgttgatat
    18841 tggtattcag ctctgttttc gtgtcactga ttttattgtc agtgtagcta tttgatgaac
    18901 tgatcgcgtc gttcttcgcc ttgtcaatac tggcattcag ctccgtcttc gtgtcactga
    18961 ttttattgtc agtgtaactg ttggacgaac tgaacgcatc gttctttgcc ttatcgatac
    19021 tggcgttcag ttctgtcttc gtgtcactga ttttactgtc agtgtaactg ttggatgaac
    19081 tgatcgcgtc gttctttgcc ttatcaatat tggcattcag ttctgtcttc gtgtcactga
    19141 ttttgctgtc ggtgtagttg ttcgacgaat tgatcgcgtc atttttcgca ctatcaatat
    19201 tcgtattgag ttcatttttg gcatcagtaa ttttattgtc tgtatagttg tttgcgttct
    19261 tttctgccgc ttcagctttt tctgccgcat cctggattgc ctggttagct gtcgattgag
    19321 cattttgagc aaccgtattg gcagagttcg ctgtgttttg cgcggtattc gccgtattca
    19381 gtgcgttctg tgccgctgaa ttggcctcat ttgctgttgt ctgcacttta ttcgcggctg
    19441 tttgcgcgtt ttgtgcagta gacgcagcat tattcgcgac agactgcgca ttttgggctg
    19501 tagaagcagc accatttgca acattttgtg cattctgtga gtttgacagc gcactattgg
    19561 ctatgccttt taccccatcg acacaatccg aaatattaag agtctcctta ttacctgtaa
    19621 ggtaatactc acaatctgca tatgcactac cagcagataa gcacaataaa acagctataa
    19681 tagatttggt tactttcatt tctaacctca gtgattgtaa ctaatcatca cattccgttg
    19741 gcgcggtatg tgatacttgc agtcccctga tacccgttgg cgcgggtatc aggttttaat
    19801 cagcctctga cgcgaccaaa cttactcatg atcagtgaga ttgcagccgg gtctgccgtt
    19861 gaacactgat ttaaaaaatt cttacggaga tcaaatgttt taccccagcg gattttcccc
    19921 tttttctttt caacattttt aaaaaaatcc ttttctgcac tgctgcactc actccctcca
    19981 ctactaccga cagctttacc ataaagacaa aaaacggatt tacagggatc agcggcatac
    20041 gttggcgcta taaaacagga cacagtaaaa attacgatta gacctttgca tatccttttc
    20101 atagtaacct ctgaatattt attcttgaca gataaatttc aacatagtca ttattcaacc
    20161 atctttttag tggctgatat tcaataacac ctgttgcacc attttttctt agccagtctt
    20221 tcgctgacca gtaactatca aaagaagatg tccttacaac tattttttca gaatgggcaa
    20281 cggcataaaa aacagaatca tcgtaaagat ggttttctgg tttaaaatca ggcaacacct
    20341 tactccatgg ggaatttata ttatctgatt taataacacc ggatgttggt ttccagttca
    20401 ttatttgtgt attcataact tcaggcattt tttcccattc aacctgtggc ggttcaggtg
    20461 gagaggaaca ggctgtgagg acaagaatac tgatcataag tatttttttc atagcaaaac
    20521 ctcagactcc agctctccta cggagagcat tttttctttt gacggatatt taagcccttt
    20581 cacaccaaat atttttttcg tcttatttag tttcatcgtc aatgatgcca gtttaggact
    20641 gaccttcatt aacctgtcca taaaatacgg atcaaggtaa taaagtgcct tttctgcttt
    20701 aacagggttc tcccccttca ggatgataaa ctcttcttta aagtccagcg ttcccagttc
    20761 ctgtggaagc accagtgctc ttcgggcttc actttctgat tcgccctgtg aagttgatcg
    20821 tccccggttc ttgcttgtgc tctttgatgt agtggtaata tacccaagtt tttctgatat
    20881 cttcgcggca tcatcctctt cactgacagc atagataata cggcagggat gagcactcat
    20941 cagtgttttg gctccctcaa taccatagat ttcatttagc tgactgatat tctgataaat
    21001 tgtcagcagt ttaagtttga aacctgcaat ataccctgat ccctttttaa taa
//
