CP001179.1 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

CP001179.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	210,631	268,865

CP001179.1 - Region 1 - NRPS

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Location: 210,631 - 268,865 nt. (total: 58,235 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene overview

NRPS/PKS domains

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 210630 - 268865:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - D-Ala) + (Val)

Direct lookup in NORINE database: strict or relaxed

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NRPS/PKS substrate predictions

ctg1_225

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CAL_domain (215..652): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 26.3
shikimic_acid: 0.0
NH2: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1842..2226): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWLGGTFK
Nearest Stachelhaus code(s):: Val DAFWLGGTFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg1_226

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AMP-binding (126..563): X

nrpys: Kic

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GICWVGTSGK
Nearest Stachelhaus code(s):: Kic GICWVGTSGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1796..2196): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVANIALIYK
Nearest Stachelhaus code(s):: Ala DVANIALIYK (100% 8Å match)
Stachelhaus code match:: 100% (strong)