LOCUS       AP027224.1             12181 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  AP027224.1 Enterococcus faecium JARB-OU2352 plasmid pJAOU2352_3 DNA,
            complete sequence.
ACCESSION   AP027224
VERSION     AP027224.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 20:07:04
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 128
            Orig. end    :: 12309
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12181
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:11410]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..11410
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12181
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12181
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             160..408
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIRM
                     LYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKK"
     CDS             863..1309
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MSWTDENEPTINNEPTSYEELELAFAKLQKKYEENNELLRLNNRK
                     LDRLEETMTNTLKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDSQVKK
                     FHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     CDS             1316..2005
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLPG
                     VIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTTCY
                     EEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQTEEA
                     CYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKSVKEW
                     LDQQQQN"
     CDS             2848..3792
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVRF
                     TFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKINGD
                     VENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFAYFS
                     KEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGYQFTF
                     KPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELLQQIKQ
                     LEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     CDS             3813..4346
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKVV
                     LRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLREQL
                     ALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATETMD
                     EQTKNWKKWWQLWK"
     CDS             4337..4531
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MEMKKEILMTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKL
                     NPNYYNSQNEEVFVEKLDK"
     CDS             5001..5225
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_8"
                     /sec_met_domain="Bacteriocin_II (E-value: 2.7e-22,
                     bitscore: 68.5, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEKC
                     WVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     CDS             5244..5531
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKSV
                     GEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     CDS             5888..6361
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MSFSELYLLYLFRYNGIANDTSVGRTERVGLMSEQNQYLASNHSK
                     KYTYRSEPKQISFRVSESEFAKLKQSAEALQMSVPAFVKAKAQNARLVTPKVAPDIAQA
                     IARDLAKAGGNINQIAKWCNTHQHDVDPGDAQRLSENLKIMQKELQKIWQQLK"
     CDS             6343..7257
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIRM
                     LYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHNHI
                     VINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKLKEK
                     NEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKKKVRS
                     NKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTTEQPEI
                     RPTRRNHDQHVERGADYQQELSF"
     CDS             7502..8191
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLPG
                     VIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTTCY
                     EEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQTEEA
                     CYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKSVKEW
                     LDQQQQN"
     CDS             9035..9979
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVRF
                     TFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKINGD
                     VENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFAYFS
                     KEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGYQFTF
                     KPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELLQQIKQ
                     LEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     CDS             10098..10532
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MIAKNERGYKVVLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAY
                     IPNKNVVANKLLDQLREENEFLREQLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQE
                     QLQLTYTEESSENSSTTLSEATETMDEQTKNWKKWWQLWK"
     CDS             10523..10651
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MEMKKEILMTKKHLLFGSILLGILSFSPMLLSVANKGNKKGN"
     CDS             11186..11410
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_16"
                     /sec_met_domain="Bacteriocin_II (E-value: 2.7e-22,
                     bitscore: 68.5, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEKC
                     WVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     CDS             11370..11717
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MVGLIMVHGHLEGSGREVIIMDFTKEEKLLNAISKVYNEATIDDY
                     PDLKEKLFLYSKEISEGKSVGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQV
                     YRGWASIGIWS"
ORIGIN
        1 agacattgct caggcaatcg cgcgcgattt agccaaagct ggcgggaata tcaatcaaat
       61 tgccaagtgg tgcaacacac accaacacga cgttgatcct ggcgacgccc aacgcttatc
      121 cgaaaaccta aaaatcatgc aaaaggagct acaaaagata tggcaacagt taaagtaagc
      181 cgaaccactt cttgtagccg agcgatcaat tacgccgaac cacgagcaac cgtcaaaaca
      241 gggataaact gtgacattga ttatgccaaa agcgaaatga aacaaattcg catgctgtat
      301 ggaaaagacg atcgtgtaca agcacactta ttgatccagt cttttcgacc aggagaaatt
      361 accgctgaaa aagccaatca actaggggca gagtatgcga aaaaatagcc cctgaccacc
      421 aaatcgcgat ttacacacat acagacaaag accatattca taaccacatt gtcattaact
      481 ccgtcaatct ggaaactggg aacaaatttc aagcccatgg tcaagcattt ttaaacaaat
      541 gttatgacct aaatgacgag atttgtcttg aacatgactt aacaatcact gaacgaggaa
      601 gaaacccgaa aaacgaacca tgtctgaaat caaattaaaa gaaaaaatga acctgtttgg
      661 aaagacgaaa ttcggtttgc gattgatcaa acaatgaaaa acaaaaaaac tcgaacgtat
      721 aaccaatttt gtgattctct taaaacattc ggcattcatt gcttgaatcg tgggaaaaat
      781 tttacttacg aattgatcca caaaaagaaa aaagtacgat ccaacaaact aggaaaggat
      841 tacgaaaagg agacgatttt acatgagctg gacagacgag aacgagccta caatcaacaa
      901 cgaaccaacg agctacgaag agctcgagct agcattcgcg aaactgcaaa agaagtacga
      961 agagaacaac gaactcttac gactgaacaa ccggaaatta gaccgactcg aagaaaccat
     1021 gaccaacacg ttgaaagagg agcagactac caacaagaat tatcgttcta aaacgttaca
     1081 agacatagaa aatgaaataa agaaacaacg tgcttttctt gcaccttata ccaaagaaag
     1141 aatacaaact acaattgatt cacaagtcaa aaaattccac catgcgctat taaaccagcg
     1201 aaataaagaa cagaaaaaag taattatgca gcgatcaatg gatattcttg cccccttatg
     1261 ttgcttaatc atgacactgt tagccttttg gctggtatgg ggagaataaa tagaaatggc
     1321 attctattta ccctatctac tcatttttgc cagtatttta ggaattattt ggcttagcta
     1381 taaggcttat caaacaagat attcattaaa aggctctaaa attcgattta agaggttttt
     1441 attgccaggg gttatattta cattatcaat cgttttaagt ggtttattcg gcgttttaga
     1501 gggaaataaa cgtatttcaa gaagtatttt attaggggat atcactcaaa agtatgaagc
     1561 agcatgtgat aaaaagaaaa aggagcaagt gttaacacaa aaaatggaag agtttaccac
     1621 ttgttatgag gaaatgaacg atatttttgt gaatcaagaa aaacgtttga cggataaaaa
     1681 catggaaaaa ctcactcgtc tttatcaaaa cttgccagaa aaacagcaaa aagaggttca
     1741 agacaactat gagcgaacca aaaaagacgt gcaatatttt aaagatacgc agacagaaga
     1801 agcttgttat aatttattca gtgatacaat ccctttttca actagtgaac aggaacgaaa
     1861 agaacggcaa caatcagtta cctacgaacg ttataaagca ctgcttcagc aagcaacgaa
     1921 catacaaaat ccaacgaaaa aagaaacggc attaaattat ctaaaaagtg tcaaggaatg
     1981 gttagatcag caacagcaaa attgaatttg atcggcaatc atgttaaact aaacatgcaa
     2041 atgatcaaac attagataca cgaaagcccc agagaggtcg gattctctgg ggcttttttt
     2101 caggttgatg tcgcctttat tgattttact tcttgtttcg gttattcaac caataactga
     2161 ataaagagac acaaacttct ataagaaggg ggcaaatgaa caattcaaac attagataca
     2221 cctccttcca gtcgcaagac tgtcggatag gcgacaagtt attatatctt aaaaaattaa
     2281 acttgtgtgg tgtttttaag tatcgcttat tttagggttg ttagggcttg ccctgaccgc
     2341 ctgtaaggcg ctttaaagct agataaggat ttttatccaa gactgtctta aaacggctta
     2401 gataagcatt cagaaccgct caaaggcctc tttaccaaca tgtttttagc aaaggagcct
     2461 ttaggcgact gcgcagtaca atgtgagagc gtagcgatca cacctttttg gcgaccgtag
     2521 gaagcaaggt tttggattgg cagttttgaa aaatgcgcga acctgtttaa agaaaaaaga
     2581 agtggttttt aggcgggaaa attagccccc tctttttata tctcttttta aacctctttt
     2641 taaacctctt taccgtaagc tgtgtcctta ctctaccaat ggatacagaa tgttatgaag
     2701 gacattttgt ctgtttatga aggacatttt gtctgtttat gaaggacatt ttgtctgttt
     2761 atgaaggaca ttttgtctgt ttgaacgtca aatatgaatg tcttgacatt taaaaaatgt
     2821 cattcataat tggattgagg tgattatatg gctaatgaga ttgtaaaata ccaccatgaa
     2881 ttaaatacaa ttcctttaag aaaatttaca ccggttgaaa tgaatttgtt tttttccatc
     2941 gtgtctagaa tgcgtgaaaa aggggataag acagttcgtt ttacgtttga ccaactaaaa
     3001 gatttaagta actacaaagc aactgcaaat gtacgatttg tagaagattt aaaagcaact
     3061 tatgaaaaaa tcttatcttt acgctttggt cgtagaagtg agtctgggct ttcttacgat
     3121 atgtttgtaa tgtttacaga atttaaaatc aacggggacg tagaaaatcc ttacgtagat
     3181 atacgaattt acgaaaaagc actgcctttg ttaaataatt tagacgagtg ggtacgctat
     3241 tctttacaac aattcaacga gctacaaagt ggctatgcaa agactatgtt tcgtctgtta
     3301 aagcaataca gaaccaaagg tttcgcatat ttctccaaag aagactttct tgaattatta
     3361 gatattccta aaagttataa gcaacctgat atagataaac gagttataaa acctatacgt
     3421 caagaactaa ctgcaatctt caaaggacta acaatcaaaa agaaatacgg aaaaggacgg
     3481 ggaaaacctg ttattggcta tcaatttacg ttcaaacctg agatcaaaaa agcagacgac
     3541 tttaacaaac atgcaccaac caaagaagac caaaataaag cattggcttt agctgataaa
     3601 caaaaagaat acgaagaacc cgctacaaca attaacgaaa aaatcaaaca gaagaaacga
     3661 gaacttgaac tcctccaaca aatcaaacaa ctagaaaaag agaaaaaagc tcttgaaaaa
     3721 caaacagagt ccgcactttc ggaaaaagag aaaaaaagtt tattatctga tttagataat
     3781 ttattccagt agcaacctag gaggcaacca gtatgcaacc acaagaaacc tttacaataa
     3841 aggaattgtc agatcttttt aagatgagta ggcaagcaat atcgaaacat atccaaaaat
     3901 tagattcttc catgatagct aaaaatgagc gtggttataa ggttgtattg cgttctggag
     3961 tattgcaact tgctcgcaac ttagacaatc aaaggttgct agataagttg cataaacatg
     4021 aacaaaacaa cgataaaaat gcttatatac caaacaaaaa cgtggttgca aacaagttgc
     4081 tagatcagtt gcgtgaagaa aatgaatttt tacgagaaca acttgccctc aaagagcaaa
     4141 ataattctca tatacaaaaa ctactcgacc agcaacaaca actcaccctg caagccaacc
     4201 aacaaatcga aaaacttcag gagcaactgc agttgactta tacggaagag tcttcagaga
     4261 atagttcaac gactctttct gaagcaacag aaacaatgga cgaacaaaca aagaattgga
     4321 aaaaatggtg gcagctatgg aaatgaagaa ggaaatactt atgacaaaaa aacacttgct
     4381 attcggttct atcctactag gaatattaag ctttagccca atgttattat cagtggccaa
     4441 caaaggaaat aaaaaagggg aactaaaact caatcctaat tactacaaca gtcaaaatga
     4501 ggaagtattt gtagaaaaac ttgataaata agaaaagact gctcgtacga gcagtctttc
     4561 tgaaagagat tatcctatta ttaaccttag aaaagaataa taaatgaata tgagatatgt
     4621 aaaaagcata acaaacacaa acaaaaataa caagtattta aaaaatgacc gatcaatatt
     4681 cacaaagaat tagaaagaaa caaccgcaga aaaccaagcc ttaaaaagag cttttaacct
     4741 agaccaataa aaattcacaa aatcagcgcc tggatccctt ggtacaggcg ttacttggta
     4801 gtatacacat tatgtctact agctgtttaa ataactgatc ttataatttt atttaaacga
     4861 ttatgaattc aaaactactt tttatgacgt taatcattgt tatataataa attgttatat
     4921 aataaaatgt tatataataa aattactaag attatttaat ataacaagca attttaaaaa
     4981 aacgaaaagg aaaaacaatc atgaaaaaga aagtattaaa acattgtgtt attctaggaa
     5041 tattaggaac ttgtctagct ggcatcggta caggaataaa agttgatgca gctacttact
     5101 atggaaatgg tctttattgt aacaaagaaa aatgttgggt agattggaat caagctaaag
     5161 gagaaattgg aaaaattatt gttaatggtt gggttaatca tggtccatgg gcacctagaa
     5221 ggtagtggta ggaggttatt ataatggatt ttactaaaga agaaaaactt ttaaatgcaa
     5281 ttagtaaagt atacaatgaa gcaactatag atgactatcc tgacttaaaa gaaaagctct
     5341 ttctttattc taaagaaatc agtgagggaa aaagtgttgg tgaagttagt atgaaattaa
     5401 gtagttttct tggaagatat attttaaaac ataaatttgg attacctaaa tctttaatag
     5461 aattacaaga aattgttagt aaggaatctc aagtatatag aggatgggct tctattggta
     5521 tttggagtta attctttgga ataaaatgaa aatgggactg aagaatcaat tctgattcat
     5581 cagtcccata aattatagag ccgaaaaatt atcatattta tagatttatt aatagtaaat
     5641 ggcataagaa tctttgaaca acgaaaaaaa tgtagctcta cctaattatt gatttgcaac
     5701 aatttcaccg aaggtgaaac aagcgaaact ttacaaaaag tggctagcat ttgctagtct
     5761 tttttgtatt gtggagagtg ggggggaggg ggattcaagg gggagcttgc gcccctttga
     5821 caagcggtta tttgcaccaa atacgtaggt atttggctag caaatataga gcttgccaag
     5881 ccctttagtg agctttagtg agctttactt attgtacctt tttaggtaca atggtattgc
     5941 gaacgatacg tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaata
     6001 tttggctagc aatcattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt
     6061 tcgagtgagc gaatccgaat ttgcaaagct gaagcagtca gctgaagctt tgcaaatgag
     6121 tgtgccggct ttcgtgaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc
     6181 gccagacatt gctcaggcaa tcgcgcgcga tttagccaaa gctggcggga atatcaatca
     6241 aattgccaag tggtgcaaca cacaccaaca cgacgttgat cctggcgacg cccaacgctt
     6301 atccgaaaac ctaaaaatca tgcaaaagga gctacaaaag atatggcaac agttaaagta
     6361 agccgaacca cttcttgtag ccgagcgatc aattacgccg aaccacgagc aaccgtcaaa
     6421 acagggataa actgtgacat tgattatgcc aaaagcgaaa tgaaacaaat tcgcatgctg
     6481 tatggaaaag acgatcgtgt acaagcacac ttattgatcc agtcttttcg accaggagaa
     6541 attaccgctg aaaaagccaa tcaactaggg gcagagtatg cgaaaaaaat agcccctgac
     6601 caccaaatcg cgatttacac acatacagac aaagaccata ttcataacca cattgtcatt
     6661 aactccgtca atctggaaac tgggaacaaa tttcaagccc atggtcaagc atttttaaac
     6721 aaatgttatg acctaaatga cgagatttgt cttgaacatg acttaacaat cactgaacga
     6781 gggaagaaac ccgaaaaacg aaccatgtct gaaatcaaat taaaagaaaa aaatgaacct
     6841 gtttggaaag acgaaattcg gtttgcgatt gatcaaacaa tgaaaaacaa aaaaactcga
     6901 acgtataacc aattttgtga ttctcttaaa acattcggca ttcattgctt gaatcgtggg
     6961 aaaaatttta cttacgaatt gatccacaaa aagaaaaaag tacgatccaa caaactagga
     7021 aaggattacg aaaaggagac gattttacat gagctggaca gacgagaacg agcctacaat
     7081 caacaacgaa ccaacgagct acgaagagct cgagctagca ttcgcgaaac tgcaaaagaa
     7141 gtacgaagag aacaacgaac tcttacgact gaacaaccgg aaattagacc gactcgaaga
     7201 aaccatgacc aacacgttga aagaggagca gactaccaac aagaattatc gttctaaaac
     7261 gttacaagac atagaaaatg aaataaagaa acaacgtgct tttcttgcac cttataccaa
     7321 agaaagaata caaactacaa ttgattcaca agtcaaaaaa ttccaccatg cgctattaaa
     7381 ccagcgaaat aaagaacaga aaaaagtaat tatgcagcga tcaatggata ttcttgcccc
     7441 cttatgttgc ttaatcatga cactgttagc cttttggctg gtatggggag aataaataga
     7501 aatggcattc tatttaccct atctactcat ttttgccagt attttaggaa ttatttggct
     7561 tagctataag gcttatcaaa caagatattc attaaaaggc tctaaaattc gatttaagag
     7621 gtttttattg ccaggggtta tatttacatt atcaatcgtt ttaagtggtt tattcggcgt
     7681 tttagaggga aataaacgta tttcaagaag tattttatta ggggatatca ctcaaaagta
     7741 tgaagcagca tgtgataaaa agaaaaagga gcaagtgtta acacaaaaaa tggaagagtt
     7801 taccacttgt tatgaggaaa tgaacgatat ttttgtgaat caagaaaaac gtttgacgga
     7861 taaaaacatg gaaaaactca ctcgtcttta tcaaaacttg ccagaaaaac agcaaaaaga
     7921 ggttcaagac aactatgagc gaaccaaaaa agacgtgcaa tattttaaag atacgcagac
     7981 agaagaagct tgttataatt tattcagtga tacaatccct ttttcaacta gtgaacagga
     8041 acgaaaagaa cggcaacaat cagttaccta cgaacgttat aaagcactgc ttcagcaagc
     8101 aacgaacata caaaatccaa cgaaaaaaga aacggcatta aattatctaa aaagtgtcaa
     8161 ggaatggtta gatcagcaac agcaaaattg aatttgatcg gcaatcatgt taaactaaac
     8221 atgcaaatga tcaaacatta gatacacgaa agccccagag aggtcggatt ctctggggct
     8281 ttttttcagg ttgatgtcgc ctttattgat tttacttctt gtttcggtta ttcaaccaat
     8341 aactgaataa agagacacaa acttctataa gaagggggca aatgaacaat tcaaacatta
     8401 gatacacctc cttccagtcg caagactgtc ggataggcga caagttatta tatcttaaaa
     8461 aattaaactt gtgtggtgtt tttaagtatc gcttatttta gggttgttag ggcttgccct
     8521 gaccgcctgt aaggcgcttt aaagctagat aaggattttt atccaagact gtcttaaaac
     8581 ggcttagata agcattcaga accgctcaaa ggcctcttta ccaacatgtt tttagcaaag
     8641 gagcctttag gcgactgcgc agtacaatgt gagagcgtag cgatcacacc tttttggcga
     8701 ccgtaggaag caaggttttg gattggcagt tttgaaaaat gcgcgaacct gtttaaagaa
     8761 aaaagaagtg gtttttaggc gggaaaatta gcccccctct ttttatatct ctttttaaac
     8821 ctctttttaa acctctttac cgtaagctgt gtccttactc taccaatgga tacagaatgt
     8881 tatgaaggac attttgtctg tttatgaagg acattttgtc tgtttatgaa ggacattttg
     8941 tctgtttatg aaggacattt tgtctgtttg aacgtcaaat atgaatgtct tgacatttaa
     9001 aaaatgtcat tcataattgg attgaggtga ttatatggct aatgagattg taaaatacca
     9061 ccatgaatta aatacaattc ctttaagaaa atttacaccg gttgaaatga atttgttttt
     9121 ttccatcgtg tctagaatgc gtgaaaaagg ggataagaca gttcgtttta cgtttgacca
     9181 actaaaagat ttaagtaact acaaagcaac tgcaaatgta cgatttgtag aagatttaaa
     9241 agcaacttat gaaaaaatct tatctttacg ctttggtcgt agaagtgagt ctgggctttc
     9301 ttacgatatg tttgtaatgt ttacagaatt taaaatcaac ggggacgtag aaaatcctta
     9361 cgtagatata cgaatttacg aaaaagcact gcctttgtta aataatttag acgagtgggt
     9421 acgctattct ttacaacaat tcaacgagct acaaagtggc tatgcaaaga ctatgtttcg
     9481 tctgttaaag caatacagaa ccaaaggttt cgcatatttc tccaaagaag actttcttga
     9541 attattagat attcctaaaa gttataagca acctgatata gataaacgag ttataaaacc
     9601 tatacgtcaa gaactaactg caatcttcaa aggactaaca atcaaaaaga aatacggaaa
     9661 aggacgggga aaacctgtta ttggctatca atttacgttc aaacctgaga tcaaaaaagc
     9721 agacgacttt aacaaacatg caccaaccaa agaagaccaa aataaagcat tggctttagc
     9781 tgataaacaa aaagaatacg aagaacccgc tacaacaatt aacgaaaaaa tcaaacagaa
     9841 gaaacgagaa cttgaactcc tccaacaaat caaacaacta gaaaaagaga aaaaagctct
     9901 tgaaaaacaa acagagtccg cactttcgga aaaagagaaa aaaagtttat tatctgattt
     9961 agataattta ttccagtagc aacctaggag gcaaccagta tgcaaccaca agaaaccttt
    10021 acaataaagg aattgtcaga tcttttaaga tgagtaggca agcaatatcg aaacatatcc
    10081 aaaaattaga ttcttccatg atagctaaaa atgagcgtgg ttataaggtt gtattgcgtt
    10141 ctggagtatt gcaacttgct cgcaacttag acaatcaaag gttgctagat aagttgcata
    10201 aacatgaaca aaacaacgat aaaaatgctt atataccaaa caaaaacgtg gttgcaaaca
    10261 agttgctaga tcagttgcgt gaagaaaatg aatttttacg agaacaactt gccctcaaag
    10321 agcaaaataa ttctcatata caaaaactac tcgaccagca acaacaactc accctgcaag
    10381 ccaaccaaca aatcgaaaaa cttcaggagc aactgcagtt gacttatacg gaagagtctt
    10441 cagagaatag ttcaacgact ctttctgaag caacagaaac aatggacgaa caaacaaaga
    10501 attggaaaaa atggtggcag ctatggaaat gaagaaggaa atacttatga caaaaaaaca
    10561 cttgctattc ggttctatcc tactaggaat attaagcttt agcccaatgt tattatcagt
    10621 ggccaacaaa ggaaataaaa aggggaacta aaactcaatc ctaattacta caacagtcaa
    10681 aatgaggaag tatttgtaga aaaacttgat aaataagaaa agactgctcg tacgagcagt
    10741 ctttctgaaa gagattatcc tattattaac cttagaaaag aataataaat gaatatgaga
    10801 tatgtaaaaa gcataacaaa cacaaacaaa aataacaagt atttaaaaaa tgaccgatca
    10861 atattcacaa agaattagaa agaaacaacc gcagaaaacc aagccttaaa aagagctttt
    10921 aacctagacc aataaaaatt cacaaaatca gcgcctggat cccttggtac aggcgttact
    10981 tggtagtata cacattatgt ctactagctg tttaaataac tgatcttata attttattta
    11041 aacgattatg aattcaaaac tactttttat gacgttaatc attgttatat aataaattgt
    11101 tatataataa aatgttatat aataaaatta ctaagattat ttaatataac aagcaatttt
    11161 aaaaaaacga aaaggaaaaa caatcatgaa aaagaaagta ttaaaacatt gtgttattct
    11221 aggaatatta ggaacttgtc tagctggcat cggtacagga ataaaagttg atgcagctac
    11281 ttactatgga aatggtcttt attgtaacaa agaaaaatgt tgggtagatt ggaatcaagc
    11341 taaaggagaa attggaaaaa ttattgttaa tggttgggtt aatcatggtc catgggcacc
    11401 tagaaggtag tggtagggag gttattataa tggattttac taaagaagaa aaacttttaa
    11461 atgcaattag taaagtatac aatgaagcaa ctatagatga ctatcctgac ttaaaagaaa
    11521 agctctttct ttattctaaa gaaatcagtg agggaaaaag tgttggtgaa gttagtatga
    11581 aattaagtag ttttcttgga agatatattt taaaacataa atttggatta cctaaatctt
    11641 taatagaatt acaagaaatt gttagtaagg aatctcaagt atatagagga tgggcttcta
    11701 ttggtatttg gagttaattc tttggaataa aatgaaaatg ggactgaaga atcaattctg
    11761 attcatcagt cccataaatt atagagccga aaaattatca tatttataga tttattaata
    11821 gtaaatggca taagaatctt tgaacaacga aaaaaatgta gctctaccta attattgatt
    11881 tgcaacaatt tcaccgaagg tgaaacaagc gaaactttac aaaaagtggc tagcatttgc
    11941 tagtcttttt tgtattgtgg agagtggggg gagggggatt caaggggagc ttgcgcccct
    12001 ttgacaagcg gttatttgca ccaaatacgt aggtatttgg ctagcaaata tagagcttgc
    12061 caagcccttt agtgagcttt agtgagcttt acttattgta cctttttagg tacaatggta
    12121 ttgcgaacga tacgtccgta ggacgtactg aaagggtggg acttatgagc gaacaaaatc
    12181 a
//
