LOCUS       AP014952.1             12799 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  AP014952.1 Klebsiella oxytoca plasmid pKO_JKo3_1 DNA, complete
            genome, strain: JKo3.
ACCESSION   AP014952
VERSION     AP014952.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 17:15:48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 69426
            Orig. end    :: 82225
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12799
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7799]"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7799
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     cand_cluster    1..12799
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12799
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="1"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     CDS             1662..2387
                     /locus_tag="ctg1_84"
                     /transl_table=11
                     /translation="MRAQHTFPGATDRWLHRLLTWAPGQTDMIKTVALVLMVTDHTGLL
                     LAGNNEVMRLLGRGCFPLFGLAWGMNLARHAEIRQSQLNSLWGWALVAQVSFMLIGYPW
                     YSGNILFAFAVTGQVLRWVSQPSWYYTLPAAGLLVAWIPLSTASYGMAGVGMLTASWLL
                     CRAQHAQERLGYGVLWALMVLLMNMHDVSESVAGLAIALLTLMVCSSAGERVKRFWPRQ
                     FFVMFYAVHLAVLGIVVTM"
     CDS             2544..3140
                     /locus_tag="ctg1_85"
                     /transl_table=11
                     /translation="MSEEKRPVLSLKRKPAENSTAPAEATPAPGVVRRKKVVVVSSPPA
                     WKAKKEKLEKVKQAAEAAARNAAPVPVKAVKTPPPVRYLRLLPPEQAIMTLKAFWPQLF
                     DGNSPRLLATGMREQLFADIVNRDLPLSHKQVIKCLKSLTRSAGYLSRMKEGAARYDLQ
                     GNAVATVTAGEAQYASERMMKELLRTERMRSQSAG"
     CDS             3160..3507
                     /locus_tag="ctg1_86"
                     /transl_table=11
                     /translation="MDFEARKQKALAIMASCKMWKSNYAPLLIRLLWRLGINIPPLPFA
                     PLWQVFGVMTGSFSVGYGLWMYWMVWRAQGMPPLFACKISLIAGVLFGLTMALFHLWRR
                     KVNKLPDWKDL"
     CDS             3978..4622
                     /locus_tag="ctg1_87"
                     /transl_table=11
                     /translation="MFKYFILRTQQQLFCYFCGIVLAMVVMLLFPSVLRGSGFYLLLSS
                     VALFWAGLALYTRHIDRMRKPEVTPLVSIRDGIQVVAEVPRHEKARLEWEILRDDEVFR
                     QQRWELTGLTGRVISRGLLYTPAVMLGGIGILAWGSPQDAIRLINALRNMPAAELVHQI
                     GFVLCLFLQISVISVLIADVVAGRGLPNVFRRALLDRLPAEFCLIRRGTER"
     CDS             4619..4729
                     /locus_tag="ctg1_88"
                     /transl_table=11
                     /translation="MRKTTGLTISAIAREFNTTRQTILRVRAAMEDSNPL"
     CDS             complement(5001..6392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176:alkyl hydroperoxide reductase subunit (Score:
                     55.3; E-value: 7.4e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_89"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.7e-16, bitscore:
                     53.0, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 5.4e-14, bitscore:
                     46.3, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKFDVIVVGAGPAGMSAAIRMRTFGLSVLVVDEQPGPGGQLWR
                     NIEGVAGSPLGQILGKEYESGASVAADFRACGAVYEPNTQVWQLEPSWRVFLRRDGKTE
                     SVEAKEIVLATGAQERPAPFPGWTLPGVMPVGGAQILLKNARQIPEGPTWVVGSGPLPI
                     LYMAQVIRAGGTIEGWLDTSAPGEWRRALPWLREAFWGRKDILKGLVWLNQIKRSGTRR
                     IRGIQSFRALGEGRLQELEYTLSSGVTRRVSVNAVLVHEGVVPSVHVTRSLGLQHHWSH
                     QQNCLVPTLDIWGRGSIAGISVAGDGAGIGGGLAACTRGEIVALGIALRAGLLAQKKAD
                     ALALPLRLRLKKLLGIRPMLDALYPPPQRLVSPADETIVCRCEELTAGDIRRAAALASP
                     GINQLKAFTRAGMGPCQGRQCGYTIANIIASEQKRQVTQQDFYRIRPPLKPVTLGEIIS
                     LQVDD"
     CDS             complement(6389..6688)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_90"
                     /sec_met_domain="Fer2_4 (E-value: 7.6e-22, bitscore: 71.1,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRKLNQPAGSQKLVIYIDGVATEAEAGETVAAVLLRQSKLMSRT
                     TPVQMSERAPYCMMGVCFDCLAVVNGQGSVQTCLVTVEDNMHVERQMGRRSLNK"
     CDS             complement(6672..7799)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 190.9;
                     E-value: 6.7e-58)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_91"
                     /sec_met_domain="DAO (E-value: 6.8e-49, bitscore: 161.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQREYDLIVVGAGMTGAAIAWGLSKLPLRVLMLDAEDTDLRAAKA
                     NFGLVWSAGKGLGDPAYQRLSVEAVSQWPAFARELEDESGLTLNYENNGGLEFCLSEEE
                     FSNFSREMSEWIAQMPELSHPVQMLRRSELNARFPDIRLGKDVVGACFGPTDGHVNPLR
                     LLSALHKAFLLRGGFIQNNSRVRQISSLADGGFEVITEHASFRSGQVLLAAGLGNVTLA
                     PMVGLEAPVAPLRGQLLVTERLASFLPLPSGEIRQTAEGTVMIGATHEDVGFDLSTTTA
                     GATRMAARAIKTLPALSGAKIVRQWSALRIMTPDGSPVYASSVTCPGAHLAVCHSGVTL
                     ASFHASQYARILASGDTYPDSLSPFHYGRFHVQEA"
     CDS             8550..9380
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091:glutamine-binding lipoprotein glnH (Score: 195;
                     E-value: 2e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_92"
                     /transl_table=11
                     /translation="MKFAIATLFAAAAFSTFSTYAQDTIQIATEGAYKPWSFVNDSGKL
                     DGFEIDLTNALCARIKAECKVSAQNWDGMIPALKSGKFDAIVAAMTITPKRQEVIGFSE
                     AYAASPNTFMVLKDGPLANMKSTGKTFDLSDAGNMADAELANMARELRGKTVGVQVSTT
                     AASFLHDKLKGVEVREYKTFDESELDLLAGRVDAVMANITVLSDALKRKDASIAQLAGP
                     TLVGSPFNSVAIGLRKEDAALKSQLDAGIKSLRDDGTIKKLSEKWFGVDLSPRS"
     CDS             complement(9580..10491)
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 137.1; E-value: 1.2e-41)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_93"
                     /transl_table=11
                     /translation="MHQTHRLNLRQVEAFRAVMLTGQITAAAELMFVTQPAVSRLIADF
                     ERATNLHLFDRRGNRLLPTPAAFTLMREVQSAFVGLDRIGRAAQDIGRNFAGTLRIFAM
                     PALAAGMLARYVGRFVRGRKGLHVSLEAATSPAVIEKVASGDAELGYVDFQFNRAGMLC
                     RQRSIDAVVALPQGHPLAEKMVLTRSDLIGENIIEVDPGSTYSKRLSLILEGIERTSTI
                     ETNQSLTACSIVLEGGAIAVIDHFAASEFLDRGLIIRRFEPSLEAGFTELSAVESRRGD
                     LTTEFSDGFWRFLQEELMLPKE"
     CDS             10774..11493
                     /gene_functions="transport (smcogs) SMCOG1096:polar amino
                     acid ABC transporter, inner membrane (Score: 188.4;
                     E-value: 2.4e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_94"
                     /transl_table=11
                     /translation="MSIFELFSFGEGGWGYLLLSALITTLGLAIAGMCLGAVFGICGAL
                     SALSGIHVLQALTRVYTTIMRGIPDLLVVYLFYFGSSSALTAIAHLFGAKGFVGAPEFA
                     IGVFALGIVSGAYLTEVFRGAIQAIDKGEIEAALAFGMRLRQRMVRIVLPLAFRHALSG
                     IGNVWQMVLKETALLSVIGVVELMRQSQIAGGSTHKYFTFYLAAALIYFAISWISGRGF
                     ARAEKYTMRSLNRNSGQ"
     CDS             11496..12215
                     /gene_functions="transport (smcogs) SMCOG1096:polar amino
                     acid ABC transporter, inner membrane (Score: 208.2;
                     E-value: 2.1e-63)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_95"
                     /transl_table=11
                     /translation="MLNEATFIYEMFIRMLPGIPLTLQLAATSIACGGCLGLVLALMRT
                     SGWALLDAFARAYIALFRGTPLLVQIYLIYYGLSQYPELRSSVLWPLLRQPWWCAVLAM
                     SLNTAAYVAEIIRGSIITVPRGQVEAAMACGMSTVLMYRRIIIPQALVRMLPAYGNEII
                     LMVKATALASTITLMEVTGLAAQAISETYRPVEVFAAAGVIYLGLNFLMVSIIRLLEKK
                     TSTEASSGKQTLKRSYF"
ORIGIN
        1 taccggacgg accccggagg cacagtcgca gacgctggtg atcacccatc tgaataagga
       61 ccggcgggcg ctgaacagtc tgatccatga cgcacggcgg gagaacgggg aaaccggcaa
      121 agaggaaatc accctgccgg tgctggtcac gagtaacatc cgtgacggtg aactgcgcaa
      181 actgtcgacc tggacggctc acaaggaggc ggtggcgctg gttgataacg tataccaccg
      241 tatcagcaag gtggataagg ataatcagct gatcaccctg acagacagtg aaggaaagga
      301 gcgatttatc tcaccccggg aggcatcggc agaaggcgtc acgctctatc gtcaggaaaa
      361 gatcaccgtg tctcaggggg accgaatgcg cttcagcaaa agtgacccgg agcgcggcta
      421 tgtggccaac agtatctggg aagtgcagtc tgtttcgggt gacagtgtca cgctgtctga
      481 tggcaaaatc acccgtacgc tgaccccgaa ggcggagcag gcacagcagc atatcgacct
      541 cgcctacgcc atcaccgccc acggcgccca gggggccagc gaaccgtatg ccatcgcgct
      601 ggaaggggtg gccggtggtc gggaacagat ggccagcttt gagtctgcct atgtggcttt
      661 atcccgcatg aaacagcatg ttcaggtcta caccgacaac cgtgagggct ggataaaggc
      721 catcaagcat tcacctgaga aagcgacggc gcacgatatt cttgaacccc gtaacgaccg
      781 ggcggtgaaa acagccgatc tgctgttcgg gcgggcaagg ccactggatg aaaccgccgc
      841 gggccgggca gccctgcagc agtccggtct ggcacaggga agttcaccag gaaaattcat
      901 ttctccgggg aaaaagtacc ctcagccgca tgtggcgctg ccggcatttg ataaaaacgg
      961 gaaagccgcc ggtatctggc tcagcccgct gaccgatcgg gacggacggc tggaggctat
     1021 cggcggagag ggacgaatta tgggcaatga agacgcccgg ttcgtggcgc tgcagaacag
     1081 ccgcaacgga gaaagcctgc tggccgggaa tatgggggag ggcgtcagaa tggcccgcga
     1141 caatcccgat acgggggtgg tggtgcggct ggccggtgat gaccgcccct ggaaccccgg
     1201 ggccatgacc ggtgggcggg tatgggctga accggcgccg gtggctccgg taccgcaggc
     1261 cggggctgac attatcctcc cgccagaggt actggcacag cgggcggcag aagaacagca
     1321 gcgccgggaa atggaaaaac aggcggaaca gactgcccgg gaagtggccg gggaggcgcg
     1381 taaagccggc gagccggcgg accgggtgaa agaggttatc ggggacgtca ttcgcggact
     1441 ggagcgtgac cggccgggta cggagaaaac gacgctaccg gatgatcctc agttccggcg
     1501 ccaggaggag gcgattcagc aggtggcctc agaacgtctg cagcgtgagc gtctgcaggc
     1561 tgtggagcgg gacatggttc gtgaccttaa ccgcgagaaa acactcgggg gcgactgacg
     1621 cgcctgcggc ttgtctgccg gagcgctaaa aggaaaaaaa catgagagca caacacacat
     1681 ttccaggtgc gacagaccgc tggcttcatc gcctgctgac ctgggcaccg ggacaaacgg
     1741 atatgattaa aacggtcgca ctggtactga tggtgactga ccacaccggc ttactgctgg
     1801 ccggaaacaa tgaagtgatg cgcctgctgg gacggggctg ttttccgctg ttcggtctgg
     1861 catggggaat gaatctggcc cggcacgcgg aaatacgcca gtcgcagctg aacagcctgt
     1921 ggggctgggc gctggtcgcc caggtgtcgt ttatgctcat cgggtacccg tggtattccg
     1981 ggaatattct gtttgccttt gccgtcacgg gccaggtcct gcggtgggtc agccagccgt
     2041 cctggtatta caccctcccg gcggctggac tgctggtcgc ctggataccc ctgtcaaccg
     2101 ccagctacgg catggccgga gtgggcatgc tcaccgccag ctggctgctt tgtcgcgcac
     2161 agcatgcaca ggaacggctg ggatacgggg tgctgtgggc cctcatggtg ttgctgatga
     2221 atatgcatga cgtgagtgaa tcagtggccg ggctggcgat tgcgctgctg acgctgatgg
     2281 tgtgctcatc tgccggagaa cgtgtgaaac gcttctggcc gcggcagttc ttcgtgatgt
     2341 tctatgcggt gcacctggcg gtactcggta ttgtcgtcac gatgtaaaaa aaaaccggac
     2401 acaggtccgg ggggcgggca cattgcccgt aaacgtgaca aaggggacat catcgttgtg
     2461 tccactgcat tgcgtggtga aacgatgata ccgttagcgt atcgtatagc acagacctgt
     2521 agcttttatt gatatggccc cttatgagtg aagaaaaacg ccctgtactg agcctgaaac
     2581 gaaaaccggc ggagaacagt acggcccccg cagaggcaac ccctgctcct ggtgtggtgc
     2641 gccgaaagaa ggtcgtggtg gtctcgtccc cgccggcctg gaaggcaaaa aaagagaaac
     2701 ttgagaaggt taaacaagcg gccgaagccg ccgcgcgcaa cgctgcgccg gtgccggtta
     2761 aagcggtaaa gacgccacct ccggtgcgtt atcttcgcct gctgccgccg gaacaggcca
     2821 ttatgacgct gaaggcattc tggccacagc tgttcgacgg aaactcaccc cgtctgctgg
     2881 caacgggcat gcgcgaacag ctgtttgccg acattgtgaa ccgtgacctg ccgctgtcgc
     2941 ataaacaggt gattaagtgc ctgaagagtc tgacccggtc tgcgggctat ctgtcccgga
     3001 tgaaggaggg agccgcccgc tatgatctgc aggggaacgc cgtcgcgacc gtcactgcag
     3061 gggaagcgca gtacgccagc gagcgcatga tgaaagaact cctgcgaact gagcgtatgc
     3121 ggagccagtc agctggctga atacaatcga ggagaggaaa tggattttga agcgcggaaa
     3181 caaaaggcgc tggcgataat ggccagctgt aagatgtgga aaagcaatta tgcaccgctt
     3241 ctgatacgac tgttgtggcg gctggggata aacattcccc cgctgccgtt tgctccgctc
     3301 tggcaggttt ttggcgtgat gacaggctct ttctccgtcg gatacggact gtggatgtac
     3361 tggatggtgt ggcgggccca ggggatgcca cccctgttcg cttgcaaaat cagtcttatc
     3421 gcgggcgtat tatttggcct gacgatggca ctgtttcatc tttggcggcg aaaggtgaat
     3481 aaattacctg actggaaaga tttataacgg aataaatata ggctgtcagg tgggggatat
     3541 tcccgatctg acagattcca catcctctta aaaaacatta accctgtatg gtgcggttat
     3601 tatatgtgac tgcgtccgta ctggtgttac tcttgtccgg aaaggtctgt tgtttttctt
     3661 attgtctcat agtcagaaaa atatattcaa acgaaagaga ggtaaaaggg tgaaaggcgt
     3721 tgtggctgag gcgtgtgtgt tgcccaggta tgggcaggcg cgaagaatta caagccgttc
     3781 ggtatactga atggccgatt cgggactgcc tcgtccccgg ggtatgtgac gtttataagt
     3841 gctcaatttt caatttaaat catccacttt cagaatttaa ctgatttcaa tattttcatt
     3901 gcatcacgac gggtgattta tgaaatgcac aggcattctt atcgagcgct aattatcaaa
     3961 tggaaaggaa tgttactatg tttaaatatt ttattctgcg cacacagcag cagctgttct
     4021 gttatttctg cggtatcgtg cttgcgatgg ttgttatgct cctgttccct tctgttttac
     4081 gggggagtgg gttttatctg cttttatcgt ctgttgcgct gttctgggca ggccttgccc
     4141 tttatacccg tcacatcgac cggatgagaa agccagaggt cacaccgctg gtcagtattc
     4201 gcgacggtat tcaggtggtg gccgaggtgc cgcgccatga aaaggcccga ctggaatggg
     4261 aaatactccg ggatgatgag gtgtttcgcc agcaaaggtg ggagcttact ggcctgaccg
     4321 gacgggttat cagccggggg ctgttgtata cgccggcggt gatgctgggc ggtatcggta
     4381 ttctcgcctg gggttcccca caggatgcca tccggctgat taatgctctt cgtaatatgc
     4441 ctgctgcgga actggtgcat cagattggtt ttgtcctgtg cctcttcctg cagattagcg
     4501 tcatatcagt tctgattgct gatgttgtag ccgggagagg attaccgaat gtatttcgcc
     4561 gcgcgttgct cgacaggctg ccggcagagt tctgccttat cagaagaggg acagaaagat
     4621 gaggaagacg acaggtctaa ccatcagcgc gattgcccgt gaattcaata ctacacgaca
     4681 gaccattctc agagtaagag cggcaatgga agactctaac cctttgtaga taattgcttt
     4741 ttcaatgaat cgcgccgttt atgctcttgt gcttgatgcc cgcgggtagg agttagtact
     4801 taaaggtata ggtcaatttc gccggaacac ttgcgctgga atgggataaa gatgagatgt
     4861 gccgcgctcg ctgatatctg aaaactgacg aagggcaaca tcactttata tccttaaaat
     4921 aaaagaaaag ccgaccatag gtcggctacg caaattagcg atgcagcgaa catacattta
     4981 aaacatcata tatggagcat ttagtcgtct acttgtagag agataatttc acccaacgtg
     5041 acaggtttca gcggtggtcg aatacggtaa aaatcctgct gcgtaacctg acgtttctgt
     5101 tctgaggcga tgatattggc aatggtgtat ccacattgcc tgccctgaca ggggcccatg
     5161 cccgcgcgtg taaacgcctt cagctggttt atgcccggtg aggccagagc ggccgcccgc
     5221 cggatgtcgc cggcggtgag ttcttcgcac cggcacacaa tggtttcgtc cgccggtgag
     5281 accagacgct gaggaggcgg gtaaagggca tcaagcatgg ggcgaatccc cagcagtttc
     5341 ttcaacctta accgtaacgg cagtgccagc gcatctgcct ttttctgcgc cagaaggccg
     5401 gcccggagag caatgcccag cgccacaatt tcgccgcgtg tacaggccgc cagtccgccg
     5461 ccaataccgg cgccgtctcc ggcaacagag atgccagcaa tactgcctct tccccagata
     5521 tcaagcgtgg gcaccaggca gttctgctga tgactccagt gatgttgcaa ccccagcgat
     5581 cgcgtcacgt gaacagacgg gacaacacct tcgtgcacaa gcacggcatt cacgctgacc
     5641 cgtcgggtca caccactgga aagggtatat tccagttcct gaagacggcc ttcacccagc
     5701 gcgcggaaag actgaatgcc acgaatgcga cgcgtaccgg agcgctttat ctggttcagc
     5761 cagacgagac ctttgagaat gtctttacga ccccagaatg cctccctgag ccagggaagc
     5821 gcacggcgcc attctccggg cgcgctggta tcgagccagc cctctatagt gccgcctgcc
     5881 cggataacct gagccatgta aagaatggga aggggaccac tcccgacgac ccaggtcggg
     5941 ccttcaggta tctgtctggc atttttcagc aggatctgtg cgccgcccac cggcattacg
     6001 ccgggcagcg tccatcccgg gaacggcgca ggtctttcct gtgcgccggt ggccagaaca
     6061 atctctttgg cctcaacgga ttcagttttc ccgtccctgc gaagaaatac ccgccatgaa
     6121 ggctctaact gccagacctg ggtgttgggc tcataaacgg ctccacaggc cctgaaatca
     6181 gctgccactg aagcacctga ttcatactct ttacccagga tctgtcccag aggcgaaccg
     6241 gcaacacctt caatattgcg ccagagctgg ccgcccggtc ccggctgttc atccacgacc
     6301 agcactgaca gtccgaacgt ccgcatccgg atcgccgcac tcattcctgc cggtcccgcg
     6361 ccaacgacaa tcacatcaaa tttgcggctc atttgttcag actccggcgg cccatctggc
     6421 gctcaacatg catattgtcc tcaacggtga ccagacaggt ctgaaccgat ccctgtccgt
     6481 taaccacggc cagacagtca aaacagacgc ccatcatgca gtaaggggcc cgttcgctca
     6541 tctgtaccgg cgtggtccgg ctcatcagtt tgctctggcg tagcaggacg gcagcgacgg
     6601 tttcgcctgc ttccgcttcc gttgccactc cgtcgatata gataacaagc ttttgagagc
     6661 cggctggctg attaagcttc ctgaacatgg aaccgtccgt aatgaaaagg tgaaaggctg
     6721 tccgggtagg tgtcgcctga tgccaggatc cgcgcgtact ggctggcgtg gaaagacgcc
     6781 agggtgacgc cggagtggca cacggcaaga tgcgcgcccg ggcaggttac agaagaggca
     6841 tataccgggc tgccgtctgg cgtcatgatc cgcagagcgg accactgccg gactattttt
     6901 gcgcctgaga gcgcaggcag tgtctttatc gctctcgccg ccatacgggt tgcaccggca
     6961 gtggttgtcg agaggtcaaa ccccacatct tcatgcgtgg caccgatcat cacggttcct
     7021 tcagcagtct gacgaatttc gcctgatggc agtggaagga acgatgccag cctttctgtg
     7081 acaagcaact ggccgcgaag gggggcgacg ggagcttcaa gccccaccat tggtgccagc
     7141 gttacgttac ccagccctgc agccagcagg acttgacccg aacggaaact cgcatgctct
     7201 gtgatgacct caaagccacc gtctgcaagg gatgaaatct gtctgacgcg gctgttattc
     7261 tgaataaagc caccgcgcag tagaaaggct ttatgaagcg ccgaaagcag gcgcagtgga
     7321 ttgacgtgtc cgtcagtcgg gccgaaacac gcacccacaa cgtctttgcc cagcctgata
     7381 tcgggaaagc gggcgttcag ttcgctgcgg cgtaacatct ggactggatg cgagagttcc
     7441 ggcatctgag caatccactc actcatctca cgggaaaagt tggaaaattc ttcttcgctc
     7501 aggcaaaact ccagcccacc attattttca taattgaggg tgagcccgct ttcgtcttcg
     7561 agctcccggg caaaggcggg ccattgtgag accgcctcca cggagaggcg ctgataggcc
     7621 ggatccccaa gccctttacc tgctgaccag acgagaccaa agttcgcttt agcggcccgg
     7681 agatccgtgt cttcggcatc cagcatcaga acgcgaagcg gcagctttga tagtccccag
     7741 gcgatagctg cgccagtcat accagcaccc acaactatca ggtcatactc acgttgcatt
     7801 atgcggagtt cctacaggct gaataataaa cagtgctgct gtctggtact gaacgagtaa
     7861 acggccaagg gtagtccact ggccttgagt aaaagacaac aaattgtccg ggtcttttac
     7921 agtgttttct cgggagccca gaaatacagg tgctgcgtga caggatgctt gcgaggttat
     7981 acagcttcgg caccgcagtc atggatatga aacagcgtga agaatgccaa ttcaaatgag
     8041 tttcagaagg actttcatgc gtaaatgtta tgcatgcatt aaaccgggct aggccttgct
     8101 gaatacagtt atttaatcgt tgttttttca aagaaaaatt cataatttct tcagggcaat
     8161 aaaaaatcat acttgttgct gagggccata gtgttttctt atctgacgaa tgagttaaag
     8221 aaaagctcgt tactgaatgt ttttgaggga tgagtctatc attctgatat taattgatat
     8281 ttgtcccatg aaacctgact ggacacattg tattagtttc gggcataaca ttcactcatg
     8341 acagccatct tattttttat tattcagtaa acaggcttcg tggcaacact gctgacaggt
     8401 tttaaacgtt aatgaaacca tgaaaaagac taatttcacg aaattattct tcccaataaa
     8461 accgcatctg taaaaaaaca actttaaaca aggcacggtc aataagccgc actgactttc
     8521 tattttattc aacatgaaag gccataatta tgaaatttgc tattgcaacc ctgtttgctg
     8581 ctgctgcgtt ttcaactttt tcaacttatg cgcaggatac tattcagatt gctactgaag
     8641 gggcttataa accttggtcg ttcgtcaatg acagcggcaa gctggatggt tttgaaattg
     8701 acctcacaaa tgcgctttgc gcacgaatta aggctgaatg caaagtatca gctcagaact
     8761 gggatgggat gatcccggca ctcaaatcag gcaagtttga tgcgatcgta gcggcaatga
     8821 cgattacgcc aaagcgacag gaagttatcg gattttccga agcttacgca gcgtcaccta
     8881 atacgtttat ggtgctaaaa gatggtcctc ttgcgaacat gaaatcgacc ggaaaaacgt
     8941 tcgatctgtc agacgctgga aacatggctg atgcagaact ggctaatatg gcacgggaac
     9001 tcaggggaaa aacggttggc gttcaggtgt ccacaacagc ggcctctttc ctgcacgaca
     9061 aattaaaagg ggtagaggtt cgtgaatata aaacgtttga tgagtctgaa cttgatttgc
     9121 ttgccggacg cgttgacgca gtcatggcaa acatcaccgt attgagtgat gcgctcaaac
     9181 ggaaagatgc aagtattgcc cagcttgccg gtcctacgct ggtggggtcg ccgtttaact
     9241 ctgttgcaat aggactgcgt aaagaagatg ctgcactgaa atctcagctg gatgccggaa
     9301 ttaaatctct gcgtgacgac ggcacaatta aaaaactcag tgagaaatgg ttcggggtgg
     9361 atctttctcc tcgctcctga gatgaagagt gttgctgcaa ttttaaatca gcaggctggc
     9421 gcacgtcgtc agcctgttaa ccttcatatc ctgattctcc cgcgctgggc tgttcgaaaa
     9481 tactccctgc atgttcattt aagaggagga tgaatgcacc cgataagcac actggactct
     9541 ttcatagtat ttagttatga ccctctcgct ggatgcgcgc tactctttgg ggagcatcag
     9601 ctcttcctgt aaaaatctcc agaatccatc tgaaaactcc gttgtcaaat caccccggcg
     9661 ggattccacc gcgctaagct ccgtgaaacc cgcttcaaga gagggttcaa aacgtctgat
     9721 gatcagtcct ctgtccagaa actcggatgc agcaaagtgg tcgataacgg caatagcccc
     9781 accttcgagc acgattgaac aggccgtcag tgactggttg gtttcaatcg ttgatgtgcg
     9841 ttcgataccc tcaagaatca gactcagtct ttttgaatag gttgagccgg gatccacttc
     9901 gatgatgttt tcaccaataa gatcgctgcg ggtcagcacc attttttcag ccagcgggtg
     9961 gccttgcggc agggccacca cggcatcaat tgaacgctgg cgacaaagca tacctgcacg
    10021 gttgaactga aaatccacat agcccagttc agcatcaccc gaggcgactt tttcgataac
    10081 agcgggtgac gtcgctgctt cgagagagac gtgcagacct tttcggcccc ggacaaagcg
    10141 ccctacatag cgcgcaagca tacccgctgc cagagctggc atggcaaata ttcgcagcgt
    10201 accggcgaag ttacgaccaa tatcctgcgc cgcacgtcct atccggtcca gtcccacaaa
    10261 ggcactctgt acttcccgca ttaacgtgaa cgcagccggc gtcggaagca gccggttgcc
    10321 gcgccgatca aacagatgaa gattagttgc cctttcaaaa tcggcaatca gccggctgac
    10381 ggcgggctga gtcacaaaca tgagctcggc cgcggcggtt atctgtcctg tcagcattac
    10441 tgcccggaat gcttcgacct gtcttagatt taggcggtgc gtctggtgca taacatctcc
    10501 ttatgacgca attctcctgt accggtaaaa tccttgaatc ctgtgagcag agatctgtaa
    10561 agctacaggt gaatacagta aggaggagtt gaggtcataa ataatcagta ttcagctcaa
    10621 actaacacca aaatcccacg tgattcaatg tgtaatagga agcataatat ttagtaatgc
    10681 aaggtcggca aattttgatt tttcacattc gccattccgt tgcaacactg ctgtaacagt
    10741 gaataagcat ttgtgcaata cgaaggttga gctatgtcga tatttgaact tttctcgttc
    10801 ggagagggag ggtggggtta tctgctgctg agtgcgttga taaccacgct tggcctcgct
    10861 atcgcaggga tgtgcctggg tgcagtgttt ggcatttgtg gcgcgctttc tgccttatct
    10921 ggcatacacg tgttgcaagc cttgacccgt gtttacacca ctattatgag gggcattccc
    10981 gatctgctcg ttgtttattt gttttacttc gggtcatcaa gcgctctgac agcgatagca
    11041 catttgttcg gggcaaaggg atttgtcgga gcgccggaat ttgccattgg cgtctttgcg
    11101 ctggggattg tttcgggtgc ttaccttacg gaagttttcc gtggagcgat tcaggctatc
    11161 gataaaggtg aaatagaggc tgcgctggct tttggcatgc gccttcgcca gcgaatggtt
    11221 cggattgttc tgccacttgc cttccgacat gcactgtccg ggattggtaa tgtctggcag
    11281 atggttctga aagaaacggc gttgctgtct gtcattggcg tggtcgaact tatgcgacag
    11341 tcgcaaattg ccggcggttc aacgcacaaa tattttacgt tctacctggc ggccgcgctg
    11401 atttacttcg ctatttcatg gatatcaggg cgtggttttg cccgcgcaga aaaatatacc
    11461 atgcgatccc ttaaccgcaa ttcagggcaa taaacatgct aaacgaagcc acgttcatct
    11521 atgaaatgtt tattcgcatg ctgcccggta ttcctctgac actgcagctt gcagcaacgt
    11581 ctattgcatg cggtggttgc cttgggctgg tgctggccct gatgcgaacc tcaggctggg
    11641 cattgctgga tgcatttgcg cgtgcctaca tcgccctttt ccgtggaacc ccacttcttg
    11701 tccagattta cctgatttat tacggtctga gccagtaccc tgagctgcgg tccagtgtgc
    11761 tttggccgct cctgcgccag ccatggtggt gtgctgttct ggcgatgtca ctgaatacgg
    11821 cagcgtacgt cgcggagatt attcgcggct caattatcac cgtgccaaga gggcaggttg
    11881 aagccgccat ggcttgtggc atgagcaccg tactgatgta ccgccgcatc attatcccac
    11941 aggctctggt tcgcatgctc ccagcatatg gcaatgaaat catcctgatg gtgaaagcca
    12001 ccgccctggc ctcaacaatc acgctgatgg aggtcacggg gcttgcagca caggcgattt
    12061 cagaaaccta tcgcccggtc gaagtttttg ccgctgccgg tgttatttat ctgggactga
    12121 atttcctgat ggtcagcatt attcggttgc ttgagaaaaa gacctcaacg gaggcatcgt
    12181 ccgggaaaca aacgctcaaa cgaagctatt tctgatttcg ccaacccggt gatgtttaca
    12241 gccgggagtt taccggcacg ctgcgttcca gcgtgccgat tgaaaccaac atcacaaaaa
    12301 aatcaggaca gtaaaatgaa actagccctt gccacactca ttgccattct ctccgcagca
    12361 gcagttcctg cacaggctca ggacaccatt aaaattgcaa ccgaagcctc ttttgccccc
    12421 tggtccttta ccaacgcatc aggaaagctt gatggatttg aaattgaatt tgcagatgcg
    12481 ctgtgcaccc gtattcaagc gaagtgcctg gtcagcaacc agagctggga tggtctgatc
    12541 ccctcgctga atgccggaaa atacgatgcg attgttgcct ctatgagcat tacgccgaaa
    12601 cgcctggagg ttattgactt ctcttcacct tacgctgcct ccactaactc gttcctggtt
    12661 ttaaatggaa gccctgcagg cgatttagac tccaccggca tcaacctggg tctggaagcg
    12721 gataaagaaa aagctgataa agccatcgga attatcgata aacaactgag tggaaaaatc
    12781 gttggggtac aggcttcaa
//
